Rattus norvegicus

53 known processes

Cyp2d4

cytochrome P450, family 2, subfamily d, polypeptide 4

(Aliases: Cyp2d22,Cyp2d18,Cyp2d4v2,Cyp2d6,Cyp2d4v1)

Cyp2d4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
linoleic acid metabolic processGO:004365140.970
drug catabolic processGO:004273710.950
Human
fatty acid derivative metabolic processGO:1901568380.887
fluorene metabolic processGO:001891710.886
arachidonic acid metabolic processGO:0019369200.825
drug metabolic processGO:0017144110.769
exogenous drug catabolic processGO:004273810.756
carboxylic acid metabolic processGO:00197522890.746
lauric acid metabolic processGO:004825240.714
organic acid metabolic processGO:00060822920.707
unsaturated fatty acid metabolic processGO:0033559390.664
fatty acid metabolic processGO:0006631990.581
monocarboxylic acid metabolic processGO:00327871520.572
response to peptide hormoneGO:00434342780.563
Rat
carboxylic acid biosynthetic processGO:0046394830.557
oxoacid metabolic processGO:00434362900.549
cellular catabolic processGO:00442482950.517
Human
long chain fatty acid metabolic processGO:0001676320.513
organophosphate metabolic processGO:00196373700.504
single organism biosynthetic processGO:00447113420.441
response to inorganic substanceGO:00100353770.422
Rat
chlorinated hydrocarbon metabolic processGO:004219640.406
Rat
small molecule biosynthetic processGO:00442831240.400
icosanoid metabolic processGO:0006690380.390
steroid metabolic processGO:0008202730.384
Human
alkaloid metabolic processGO:000982030.342
Human Rat
halogenated hydrocarbon metabolic processGO:004219740.333
Rat
organic hydroxy compound metabolic processGO:19016151150.294
sulfur compound metabolic processGO:0006790700.259
biphenyl metabolic processGO:0018879100.243
oxidative demethylationGO:007098920.232
Human
lipid metabolic processGO:00066292830.204
organic acid biosynthetic processGO:0016053830.202
phenol containing compound metabolic processGO:0018958300.199
homeostatic processGO:00425923310.186
catabolic processGO:00090563510.184
Human
benzene containing compound metabolic processGO:0042537220.175
pyridine containing compound metabolic processGO:0072524320.159
Rat
response to peptideGO:19016522920.156
Rat
toxin metabolic processGO:000940490.151
single organism catabolic processGO:00447122830.150
oxidation reduction processGO:00551143040.149
nucleobase containing small molecule metabolic processGO:00550863160.147
positive regulation of phosphate metabolic processGO:00459372620.143
regulation of blood vessel sizeGO:0050880890.142
response to nutrientGO:00075842480.142
response to transition metal nanoparticleGO:19902671220.134
mapk cascadeGO:00001651400.121
positive regulation of molecular functionGO:00440932300.120
lipid biosynthetic processGO:00086101280.118
organic hydroxy compound biosynthetic processGO:1901617510.117
glutathione metabolic processGO:0006749150.116
circulatory system processGO:00030131830.115
response to metal ionGO:00100382530.113
Rat
carbohydrate derivative metabolic processGO:19011353460.113
blood circulationGO:00080151830.106
cellular amino acid metabolic processGO:00065201070.105
icosanoid biosynthetic processGO:0046456180.103
regulation of phosphate metabolic processGO:00192203490.099
cellular modified amino acid metabolic processGO:0006575610.096
epoxygenase p450 pathwayGO:001937310.095
Rat
kidney developmentGO:0001822670.095
nucleotide metabolic processGO:00091172790.090
response to cesium ionGO:001016420.089
Rat
nucleoside phosphate metabolic processGO:00067532830.086
response to vitaminGO:00332731310.083
single organism behaviorGO:00447081300.083
cellular response to peptide hormone stimulusGO:00713751200.082
response to cytokineGO:00340972150.080
response to temperature stimulusGO:0009266940.078
purine containing compound metabolic processGO:00725212530.077
response to biotic stimulusGO:00096072260.076
regulation of phosphorylationGO:00423252480.076
organonitrogen compound biosynthetic processGO:19015661670.074
insecticide metabolic processGO:001714340.073
leukotriene metabolic processGO:000669180.073
positive regulation of intracellular signal transductionGO:19025331380.072
cellular lipid metabolic processGO:00442552080.071
cellular response to hormone stimulusGO:00328702470.070
response to ketoneGO:19016541820.070
Rat
medium chain fatty acid metabolic processGO:005179150.070
nitrogen compound transportGO:00717052290.069
cellular response to xenobiotic stimulusGO:0071466190.069
Rat
reproductive structure developmentGO:00486081280.066
organic cyclic compound catabolic processGO:19013611750.064
female pregnancyGO:00075651220.064
regulation of system processGO:00440572080.063
response to xenobiotic stimulusGO:0009410230.062
Rat Worm
reproductive system developmentGO:00614581280.062
positive regulation of phosphorus metabolic processGO:00105622620.062
response to acid chemicalGO:00011012220.061
Rat
regulation of phosphorus metabolic processGO:00511743490.060
trichloroethylene metabolic processGO:001897910.060
Rat
positive regulation of signalingGO:00230562700.060
positive regulation of catalytic activityGO:00430851840.059
cellular nitrogen compound catabolic processGO:00442701630.058
Human
heterocycle catabolic processGO:00467001670.058
steroid biosynthetic processGO:0006694480.057
response to extracellular stimulusGO:00099913800.056
regulation of multicellular organismal developmentGO:20000263760.055
ribonucleotide metabolic processGO:00092592310.055
liver developmentGO:0001889900.055
Rat
response to estradiolGO:00323551640.054
single organism carbohydrate metabolic processGO:00447231180.054
regulation of cellular localizationGO:00603412630.054
cellular response to peptideGO:19016531330.053
regulation of molecular functionGO:00650093980.053
Human
multi organism reproductive processGO:00447032620.053
naphthalene containing compound metabolic processGO:009042020.052
Rat
response to ionizing radiationGO:0010212590.052
Rat
regulation of lipid metabolic processGO:0019216680.051
response to corticosteroidGO:00319602350.051
response to insecticideGO:0017085210.051
reproductive processGO:00224143720.050
positive regulation of cell communicationGO:00106472710.049
naphthalene metabolic processGO:001893120.049
Rat
cellular ketone metabolic processGO:0042180510.048
aromatic compound catabolic processGO:00194391680.048
gland developmentGO:00487321550.048
Rat
response to testosteroneGO:0033574550.048
Rat
reproductionGO:00000032450.048
vascular process in circulatory systemGO:0003018960.046
organonitrogen compound catabolic processGO:19015651790.046
Human
carbohydrate metabolic processGO:00059751300.046
protein phosphorylationGO:00064683450.046
response to purine containing compoundGO:00140741260.045
response to estrogenGO:00436272320.045
xenobiotic metabolic processGO:0006805190.045
Rat
regulation of apoptotic processGO:00429813350.044
positive regulation of transportGO:00510502450.044
cellular amino acid biosynthetic processGO:0008652320.044
regulation of signal transductionGO:00099663180.043
alpha amino acid metabolic processGO:1901605710.043
regulation of ion transportGO:00432692450.042
regulation of transferase activityGO:00513381230.042
response to external biotic stimulusGO:00432072210.042
response to sulfur dioxideGO:001047730.042
Rat
coumarin metabolic processGO:000980450.041
Human Rat
central nervous system developmentGO:00074173110.041
regulation of protein modification processGO:00313991940.041
response to amino acidGO:0043200750.040
catechol containing compound biosynthetic processGO:000971390.040
chemosensory behaviorGO:000763520.039
positive regulation of blood circulationGO:1903524650.038
calcitriol biosynthetic process from calciolGO:003637820.038
negative regulation of metabolic processGO:00098923310.038
Human
intracellular signal transductionGO:00355563140.037
positive regulation of mapk cascadeGO:0043410920.037
lipid catabolic processGO:0016042460.037
developmental growthGO:00485891000.037
positive regulation of response to stimulusGO:00485842850.037
positive regulation of protein modification processGO:00314011420.037
regulation of cell cycle g1 s phase transitionGO:190280670.036
positive regulation of nitrogen compound metabolic processGO:00511733340.036
multicellular organismal reproductive processGO:00486092330.036
dopamine metabolic processGO:0042417120.036
alpha amino acid catabolic processGO:1901606200.036
limbic system developmentGO:0021761380.035
apoptotic processGO:00069153810.035
negative regulation of cellular metabolic processGO:00313242810.035
Human
regulation of intracellular signal transductionGO:19025312180.034
regulation of tube sizeGO:0035150890.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.034
astrocyte activationGO:004814340.033
secretionGO:00469033070.033
cellular response to endogenous stimulusGO:00714953770.033
alcohol metabolic processGO:0006066770.033
nicotinamide nucleotide metabolic processGO:0046496280.033
regulation of rna biosynthetic processGO:20011413810.033
regulation of blood circulationGO:19035221100.033
response to radiationGO:00093141370.032
Rat
cell migrationGO:00164771970.032
acylglycerol metabolic processGO:0006639210.032
Rat
cellular response to insulin stimulusGO:0032869810.031
glycerolipid metabolic processGO:0046486670.031
Rat
cellular protein localizationGO:00346131220.031
ion homeostasisGO:00508012120.030
chemical homeostasisGO:00488782920.030
negative regulation of multicellular organismal metabolic processGO:004425240.030
multicellular organism reproductionGO:00325042330.030
regulation of catalytic activityGO:00507903040.030
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
negative regulation of molecular functionGO:00440921330.029
Human
protein localizationGO:00081041910.029
positive regulation of biosynthetic processGO:00098913190.028
organic substance catabolic processGO:19015753160.028
Human
negative regulation of collagen biosynthetic processGO:003296640.028
positive regulation of cellular protein metabolic processGO:00322701670.028
programmed cell deathGO:00125013920.028
terpenoid metabolic processGO:0006721370.028
Human Rat
regulation of protein metabolic processGO:00512462890.027
rna biosynthetic processGO:00327743800.027
amide transportGO:00428861050.027
regulation of muscle system processGO:0090257790.027
diterpenoid metabolic processGO:0016101330.027
Rat
triglyceride metabolic processGO:0006641210.027
Rat
positive regulation of cellular biosynthetic processGO:00313282950.027
ribonucleoside metabolic processGO:00091191740.027
response to toxic substanceGO:00096361330.027
organophosphate biosynthetic processGO:00904071430.027
regulation of cell developmentGO:00602842630.026
negative regulation of transportGO:00510511360.026
regulation of cellular protein metabolic processGO:00322682670.026
regulation of rna metabolic processGO:00512523910.026
cation transportGO:00068123820.025
purine nucleotide metabolic processGO:00061632290.025
regulation of mapk cascadeGO:00434081160.025
regulation of carbohydrate metabolic processGO:0006109410.025
regulation of leukocyte activationGO:0002694450.025
cellular response to lipidGO:00713962010.025
macromolecule localizationGO:00330362520.025
Worm
agingGO:00075682410.024
Rat Worm
regulation of nucleic acid templated transcriptionGO:19035063800.024
positive regulation of phosphorylationGO:00423271770.024
metal ion homeostasisGO:00550651860.024
cellular response to oxygen containing compoundGO:19017013860.024
negative regulation of cell differentiationGO:0045596990.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
cell projection organizationGO:00300303020.023
regulation of cellular carbohydrate metabolic processGO:0010675390.023
purine ribonucleotide metabolic processGO:00091502270.023
response to insulinGO:00328681330.023
Rat
regulation of cell cycleGO:0051726730.023
rna metabolic processGO:00160704060.023
nicotine metabolic processGO:001893310.023
Rat
regulation of neurogenesisGO:00507672470.023
neuromuscular processGO:005090520.023
alcohol biosynthetic processGO:0046165380.023
amine metabolic processGO:0009308380.023
negative regulation of programmed cell deathGO:00430691830.023
transcription dna templatedGO:00063513770.023
mitotic cell cycleGO:0000278490.023
purine ribonucleoside metabolic processGO:00461281680.023
demethylationGO:007098870.022
Human
negative regulation of cell communicationGO:00106481580.022
neutral lipid metabolic processGO:0006638210.022
Rat
positive regulation of signal transductionGO:00099671750.022
purine nucleoside metabolic processGO:00422781690.022
cellular amine metabolic processGO:0044106380.022
cellular response to glucocorticoid stimulusGO:0071385680.021
nucleoside metabolic processGO:00091161790.021
cellular carbohydrate metabolic processGO:0044262720.021
pyruvate metabolic processGO:0006090270.021
response to glucocorticoidGO:00513842230.021
organic hydroxy compound transportGO:0015850770.021
leydig cell differentiationGO:003332780.021
regulation of transcription dna templatedGO:00063553740.021
regulation of intracellular transportGO:0032386650.020
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.020
response to cadmium ionGO:0046686350.020
regulation of blood pressureGO:0008217830.020
organic acid transportGO:00158491160.020
transmembrane transportGO:00550854120.020
negative regulation of neuron deathGO:1901215690.020
mitotic cell cycle phase transitionGO:0044772200.020
bile acid secretionGO:003278250.020
cellular homeostasisGO:00197252520.020
ribonucleoside triphosphate catabolic processGO:00092031220.020
response to hydrogen peroxideGO:0042542890.020
response to oxidative stressGO:00069791860.019
Rat
regulation of stress activated protein kinase signaling cascadeGO:0070302230.019
secondary alcohol metabolic processGO:190265220.019
actin filament based processGO:0030029860.019
negative regulation of macromolecule metabolic processGO:00106052600.019
positive regulation of hydrolase activityGO:0051345860.019
circadian rhythmGO:0007623880.019
lipid localizationGO:0010876620.019
Worm
regulation of cellular component organizationGO:00511283680.019
positive regulation of rna biosynthetic processGO:19026801970.019
mitotic cell cycle processGO:1903047350.019
neurological system processGO:00508772190.018
endocrine system developmentGO:0035270300.018
regulation of amino acid transportGO:0051955250.018
protein transportGO:00150311320.018
muscle system processGO:00030121150.018
positive regulation of developmental processGO:00510942830.018
cell activationGO:0001775970.018
glycosyl compound metabolic processGO:19016571820.018
catecholamine transportGO:0051937370.018
positive regulation of transcription dna templatedGO:00458931970.018
response to other organismGO:00517072200.018
regulation of cellular ketone metabolic processGO:0010565270.018
cell motilityGO:00488702020.018
cellular response to vitamin eGO:007130630.018
positive regulation of purine nucleotide metabolic processGO:1900544910.018
male sex differentiationGO:0046661640.017
progesterone metabolic processGO:004244880.017
cyclic nucleotide metabolic processGO:0009187800.017
regulation of kinase activityGO:00435491170.017
transcription from rna polymerase ii promoterGO:00063662520.017
response to organophosphorusGO:00466831020.017
isoprenoid metabolic processGO:0006720450.017
Human Rat
g1 s transition of mitotic cell cycleGO:0000082120.017
lipid storageGO:001991510.017
Worm
cellular chemical homeostasisGO:00550822470.017
vasoconstrictionGO:0042310540.017
toxin catabolic processGO:000940710.017
regulation of membrane potentialGO:00423911100.017
negative regulation of apoptotic processGO:00430661810.017
astrocyte developmentGO:001400240.017
cellular response to cytokine stimulusGO:00713451270.017
cell cycle g1 s phase transitionGO:0044843130.017
negative regulation of gene expressionGO:00106291990.016
rhythmic processGO:00485111560.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
developmental process involved in reproductionGO:00030061590.016
purine nucleoside triphosphate metabolic processGO:00091441410.016
cofactor metabolic processGO:0051186950.016
response to nutrient levelsGO:00316673700.016
positive regulation of kinase activityGO:0033674770.016
development of primary sexual characteristicsGO:00451371070.016
apoptotic signaling pathwayGO:0097190270.016
potassium ion transportGO:0006813970.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
sex differentiationGO:00075481130.016
regenerationGO:00310991630.016
negative regulation of cellular component organizationGO:0051129830.016
carbohydrate derivative catabolic processGO:19011361470.016
glucose metabolic processGO:0006006520.016
organic anion transportGO:00157111320.015
nucleotide catabolic processGO:00091661390.015
adrenal gland developmentGO:0030325110.015
positive regulation of mast cell activationGO:003300540.015
hepaticobiliary system developmentGO:0061008900.015
Rat
cell cycleGO:00070491010.015
male gonad developmentGO:0008584590.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.015
response to alkaloidGO:00432791320.015
purine ribonucleotide catabolic processGO:00091541360.015
growthGO:00400071650.015
cation homeostasisGO:00550801950.015
maternal process involved in female pregnancyGO:0060135380.015
gonad developmentGO:00084061040.015
sterol homeostasisGO:005509230.015
negative regulation of cell deathGO:00605482290.015
regulation of nucleotide metabolic processGO:00061401170.015
cellular component biogenesisGO:00440853680.015
cellular response to organonitrogen compoundGO:00714171970.015
cellular cation homeostasisGO:00300031800.015
metal ion transportGO:00300012890.015
nucleic acid templated transcriptionGO:00976593790.015
positive regulation of secretionGO:00510471400.015
respiratory system developmentGO:0060541450.015
dicarboxylic acid transportGO:0006835340.014
fatty acid derivative biosynthetic processGO:1901570180.014
protein oligomerizationGO:00512591910.014
multi multicellular organism processGO:00447061380.014
cellular potassium ion transportGO:0071804720.014
catechol containing compound metabolic processGO:0009712190.014
peptide transportGO:0015833970.014
regulation of purine nucleotide metabolic processGO:19005421150.014
regulation of cellular amine metabolic processGO:003323880.014
ribose phosphate metabolic processGO:00196932350.014
positive regulation of secretion by cellGO:19035321280.014
phospholipid effluxGO:003370010.014
cellular component movementGO:00069282480.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.014
prepulse inhibitionGO:006013410.014
response to monosaccharideGO:00342841590.014
sensory organ developmentGO:0007423740.014
canalicular bile acid transportGO:001572250.014
regulation of protein phosphorylationGO:00019321830.014
action potentialGO:0001508540.014
protein autophosphorylationGO:0046777660.014
small molecule catabolic processGO:0044282590.014
potassium ion transmembrane transportGO:0071805710.014
positive regulation of gene expressionGO:00106282440.014
acid secretionGO:0046717480.014
regulation of cell growthGO:0001558850.014
regulation of hormone levelsGO:00108171870.014
organophosphate catabolic processGO:00464341480.014
cellular response to extracellular stimulusGO:0031668730.014
vitamin d3 metabolic processGO:007064020.013
ras protein signal transductionGO:0007265290.013
defense responseGO:00069521940.013
Worm
positive regulation of epidermis developmentGO:004568410.013
olfactory behaviorGO:004204820.013
neuron deathGO:00709971270.013
regulation of g1 s transition of mitotic cell cycleGO:200004560.013
behavioral response to ethanolGO:004814910.013
positive regulation of protein tyrosine kinase activityGO:006109820.013
response to ddtGO:004668010.013
nucleoside triphosphate metabolic processGO:00091411440.013
negative regulation of amine transportGO:0051953240.013
regulation of anatomical structure sizeGO:00900661350.013
negative regulation of transcription regulatory region dna bindingGO:200067820.013
dephosphorylationGO:0016311980.013
nucleobase containing compound catabolic processGO:00346551520.013
regulation of cell differentiationGO:00455953200.013
stress activated mapk cascadeGO:0051403350.013
development of primary male sexual characteristicsGO:0046546590.013
neuromuscular synaptic transmissionGO:000727420.013
multicellular organismal response to stressGO:0033555250.013
positive regulation of cell differentiationGO:00455972170.013
regulation of stress activated mapk cascadeGO:0032872230.013
regulation of growthGO:00400081050.013
response to mercury ionGO:0046689150.013
serine family amino acid metabolic processGO:0009069120.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
negative regulation of neurogenesisGO:0050768780.013
negative regulation of mitotic cell cycle phase transitionGO:190199130.013
regulation of nervous system developmentGO:00519602640.013
regulation of response to stressGO:00801341260.013
positive regulation of programmed cell deathGO:00430681570.012
nadp metabolic processGO:0006739130.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
negative regulation of collagen metabolic processGO:001071340.012
leukotriene biosynthetic processGO:001937030.012
positive regulation of hormone secretionGO:0046887650.012
cellular response to nitrogen compoundGO:19016992100.012
negative regulation of neuron apoptotic processGO:0043524450.012
cellular alcohol biosynthetic processGO:004410820.012
cellular response to organic cyclic compoundGO:00714072020.012
protein homotetramerizationGO:0051289250.012
response to ethanolGO:00454711620.012
Rat
vitamin d receptor signaling pathwayGO:007056110.012
regulation of peptidase activityGO:0052547550.012
regulation of cellular amino acid metabolic processGO:000652120.012
spindle organizationGO:000705120.012
positive regulation of nucleotide metabolic processGO:0045981910.012
sexual reproductionGO:00199531480.012
cellular macromolecule localizationGO:00707271220.012
response to reactive oxygen speciesGO:00003021200.012
Rat
negative regulation of innate immune responseGO:004582440.012
regulation of secretion by cellGO:19035302080.012
monocarboxylic acid transportGO:0015718520.012
response to antibioticGO:0046677390.012
purine nucleoside catabolic processGO:00061521240.012
regulation of cell projection organizationGO:00313441750.012
b cell differentiationGO:003018320.012
positive regulation of neurogenesisGO:00507691650.012
catecholamine biosynthetic processGO:004242390.012
organ regenerationGO:00311001010.012
protein complex assemblyGO:00064612630.012
regulation of hydrolase activityGO:00513361430.011
regulation of sequence specific dna binding transcription factor activityGO:0051090350.011
single organism reproductive processGO:00447022970.011
phospholipid metabolic processGO:0006644610.011
vitamin d biosynthetic processGO:004236820.011
dna metabolic processGO:0006259960.011
anion transportGO:00068201780.011
adult locomotory behaviorGO:000834440.011
response to hexoseGO:00097461440.011
negative regulation of transcription dna templatedGO:00458921160.011
response to acetateGO:001003430.011
divalent inorganic cation homeostasisGO:00725071650.011
renal system developmentGO:0072001670.011
positive regulation of cellular component organizationGO:00511302000.011
membrane hyperpolarizationGO:0060081110.011
locomotor rhythmGO:004547510.011
intracellular transportGO:00469071850.011
protein targetingGO:0006605610.011
cellular response to alcoholGO:0097306870.011
catecholamine metabolic processGO:0006584190.011
hexose metabolic processGO:0019318580.011
progesterone biosynthetic processGO:000670130.011
positive regulation of protein kinase activityGO:0045860730.011
response to glucoseGO:00097491360.011
response to gonadotropinGO:0034698340.011
eye developmentGO:0001654500.011
positive regulation of inflammatory responseGO:0050729240.011
positive regulation of protein phosphorylationGO:00019341350.011
response to woundingGO:00096112540.011
response to growth factorGO:00708481890.011
purine ribonucleoside catabolic processGO:00461301240.010
signal transduction by phosphorylationGO:00230141440.010
positive regulation of leukocyte degranulationGO:004330240.010
protein homooligomerizationGO:0051260910.010
establishment of protein localizationGO:00451841410.010
response to decreased oxygen levelsGO:00362932370.010
lipid transportGO:0006869610.010
neurotrophin productionGO:003289820.010
macromolecular complex subunit organizationGO:00439333390.010
negative regulation of secretion by cellGO:1903531720.010
mesoderm developmentGO:000749820.010
fat soluble vitamin biosynthetic processGO:004236220.010
exploration behaviorGO:003564010.010
defense response to gram negative bacteriumGO:005082930.010
single organism intracellular transportGO:19025821660.010

Cyp2d4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
central nervous system diseaseDOID:33100.018
cardiovascular system diseaseDOID:128700.012
brain diseaseDOID:93600.012
hypertensionDOID:1076300.010
vascular diseaseDOID:17800.010
artery diseaseDOID:005082800.010