Rattus norvegicus

5 known processes

Sost

sclerosteosis

Sost biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of organ orientationGO:004856110.439
establishment of anatomical structure orientationGO:004856010.129
positive regulation of signalingGO:00230562700.114
regulation of cell differentiationGO:00455953200.110
positive regulation of cell differentiationGO:00455972170.110
apoptotic processGO:00069153810.109
positive regulation of multicellular organismal processGO:00512403870.107
transcription from rna polymerase ii promoterGO:00063662520.105
positive regulation of transcription dna templatedGO:00458931970.101
homeostatic processGO:00425923310.092
chemical homeostasisGO:00488782920.086
tube developmentGO:0035295890.084
positive regulation of cellular component organizationGO:00511302000.077
positive regulation of gene expressionGO:00106282440.076
regulation of apoptotic processGO:00429813350.074
regulation of cell proliferationGO:00421273590.069
response to bacteriumGO:00096172000.068
organonitrogen compound biosynthetic processGO:19015661670.068
cellular ion homeostasisGO:00068731840.068
response to molecule of bacterial originGO:00022371940.068
regulation of multicellular organismal developmentGO:20000263760.067
regulation of nucleic acid templated transcriptionGO:19035063800.065
negative regulation of cell deathGO:00605482290.063
mapk cascadeGO:00001651400.062
positive regulation of nervous system developmentGO:00519621780.062
regulation of cellular component organizationGO:00511283680.061
positive regulation of cell proliferationGO:00082842490.061
neuron developmentGO:00486662860.060
divalent inorganic cation homeostasisGO:00725071650.058
cytosolic calcium ion homeostasisGO:00514801400.057
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.057
rna biosynthetic processGO:00327743800.055
regulation of transcription from rna polymerase ii promoterGO:00063572340.053
cellular chemical homeostasisGO:00550822470.052
cellular response to stressGO:00335542690.049
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.049
inorganic ion transmembrane transportGO:00986602290.049
single organism reproductive processGO:00447022970.049
calcium ion homeostasisGO:00550741620.049
lymphoid progenitor cell differentiationGO:000232020.049
regulation of cell developmentGO:00602842630.048
positive regulation of biosynthetic processGO:00098913190.048
programmed cell deathGO:00125013920.048
negative regulation of transcription dna templatedGO:00458921160.048
single organism biosynthetic processGO:00447113420.047
neurological system processGO:00508772190.047
regulation of catalytic activityGO:00507903040.047
cellular homeostasisGO:00197252520.046
rna metabolic processGO:00160704060.045
positive regulation of developmental processGO:00510942830.045
negative regulation of macromolecule metabolic processGO:00106052600.045
transcription dna templatedGO:00063513770.045
negative regulation of cellular metabolic processGO:00313242810.044
organ morphogenesisGO:0009887750.044
regulation of transcription dna templatedGO:00063553740.044
defense responseGO:00069521940.044
regulation of hormone levelsGO:00108171870.043
negative regulation of metabolic processGO:00098923310.043
positive regulation of phosphate metabolic processGO:00459372620.042
nitrogen compound transportGO:00717052290.041
regulation of molecular functionGO:00650093980.040
cellular divalent inorganic cation homeostasisGO:00725031620.040
cellular component assemblyGO:00226073600.039
positive regulation of nitrogen compound metabolic processGO:00511733340.039
positive regulation of phosphorylationGO:00423271770.039
negative regulation of macromolecule biosynthetic processGO:00105581480.039
positive regulation of cell developmentGO:00107201760.038
anatomical structure morphogenesisGO:00096532980.038
positive regulation of nucleic acid templated transcriptionGO:19035081970.038
cell projection morphogenesisGO:00488581230.038
negative regulation of biosynthetic processGO:00098901680.036
positive regulation of rna metabolic processGO:00512542030.036
regulation of nervous system developmentGO:00519602640.036
positive regulation of cellular biosynthetic processGO:00313282950.036
regulation of neurogenesisGO:00507672470.035
cellular component biogenesisGO:00440853680.035
protein complex assemblyGO:00064612630.035
organophosphate biosynthetic processGO:00904071430.035
peptide biosynthetic processGO:004304330.035
macromolecular complex subunit organizationGO:00439333390.034
positive regulation of cell communicationGO:00106472710.034
response to inorganic substanceGO:00100353770.034
regulation of neuron differentiationGO:00456642080.034
negative regulation of nucleobase containing compound metabolic processGO:00459341530.034
response to oxidative stressGO:00069791860.034
cellular calcium ion homeostasisGO:00068741600.033
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.033
nucleobase containing small molecule metabolic processGO:00550863160.033
response to estrogenGO:00436272320.032
cell projection organizationGO:00300303020.032
positive regulation of macromolecule biosynthetic processGO:00105572470.032
positive regulation of response to stimulusGO:00485842850.032
carbohydrate derivative metabolic processGO:19011353460.032
choline transportGO:001587140.031
neuron differentiationGO:00301823680.031
response to extracellular stimulusGO:00099913800.031
regulation of rna metabolic processGO:00512523910.031
positive regulation of molecular functionGO:00440932300.030
multicellular organismal reproductive processGO:00486092330.030
purine ribonucleotide metabolic processGO:00091502270.030
response to other organismGO:00517072200.030
secretion by cellGO:00329402480.029
response to external biotic stimulusGO:00432072210.029
organophosphate metabolic processGO:00196373700.029
regulation of rna biosynthetic processGO:20011413810.029
response to woundingGO:00096112540.029
regulation of phosphate metabolic processGO:00192203490.029
inflammatory responseGO:00069541500.029
cation homeostasisGO:00550801950.029
negative regulation of rna metabolic processGO:00512531230.028
regulation of myeloid cell differentiationGO:0045637120.028
cell part morphogenesisGO:00329901230.028
negative regulation of rna biosynthetic processGO:19026791180.027
regulation of programmed cell deathGO:00430673410.027
ribonucleotide metabolic processGO:00092592310.027
positive regulation of programmed cell deathGO:00430681570.027
regulation of organelle organizationGO:0033043800.027
carboxylic acid transportGO:00469421150.027
nucleic acid templated transcriptionGO:00976593790.027
positive regulation of phosphorus metabolic processGO:00105622620.026
digestive system developmentGO:0055123410.026
protein complex subunit organizationGO:00718223020.026
response to biotic stimulusGO:00096072260.025
organic anion transportGO:00157111320.025
protein complex biogenesisGO:00702712630.025
positive regulation of intracellular signal transductionGO:19025331380.025
regulation of mapk cascadeGO:00434081160.024
reproductive system developmentGO:00614581280.024
anterior posterior pattern specificationGO:000995210.024
protein homooligomerizationGO:0051260910.024
positive regulation of neuron differentiationGO:00456661260.023
positive regulation of signal transductionGO:00099671750.023
cell morphogenesisGO:00009021420.023
carboxylic acid metabolic processGO:00197522890.023
negative regulation of nitrogen compound metabolic processGO:00511721610.023
response to oxygen levelsGO:00704822650.022
amide biosynthetic processGO:0043604100.022
response to hypoxiaGO:00016662310.022
positive regulation of rna biosynthetic processGO:19026801970.022
catabolic processGO:00090563510.022
negative regulation of cellular biosynthetic processGO:00313271610.022
neuron projection developmentGO:00311752730.021
regulation of phosphorylationGO:00423252480.021
central nervous system developmentGO:00074173110.021
response to lipopolysaccharideGO:00324961910.021
respiratory system developmentGO:0060541450.021
regulation of phosphorus metabolic processGO:00511743490.021
cation transportGO:00068123820.021
regulation of transferase activityGO:00513381230.021
response to decreased oxygen levelsGO:00362932370.021
alcohol metabolic processGO:0006066770.021
cation transmembrane transportGO:00986552630.021
cellular response to endogenous stimulusGO:00714953770.021
organic acid transportGO:00158491160.020
regulation of signal transductionGO:00099663180.020
metanephric s shaped body morphogenesisGO:007228420.020
regulation of membrane potentialGO:00423911100.020
tissue developmentGO:00098882520.020
axis specificationGO:000979840.020
response to growth factorGO:00708481890.020
developmental inductionGO:003112820.019
negative regulation of apoptotic processGO:00430661810.019
negative regulation of multicellular organismal processGO:00512412030.019
negative regulation of programmed cell deathGO:00430691830.019
nucleoside phosphate metabolic processGO:00067532830.019
regulation of ion transmembrane transportGO:00347651210.019
morphogenesis of embryonic epitheliumGO:001633130.019
positive regulation of cellular protein metabolic processGO:00322701670.019
protein phosphorylationGO:00064683450.019
secretionGO:00469033070.019
glucose metabolic processGO:0006006520.019
mesoderm developmentGO:000749820.018
sensory organ developmentGO:0007423740.018
regulation of cell projection organizationGO:00313441750.018
mechanoreceptor differentiationGO:004249020.018
neuron projection morphogenesisGO:00488121220.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
g protein coupled receptor signaling pathwayGO:00071862420.018
cellular amide metabolic processGO:0043603440.018
epithelium developmentGO:0060429960.018
monovalent inorganic cation transportGO:00156721720.018
negative regulation of cell communicationGO:00106481580.018
purine containing compound metabolic processGO:00725212530.018
ion homeostasisGO:00508012120.017
ribose phosphate biosynthetic processGO:0046390870.017
regulation of neuron projection developmentGO:00109751610.017
positive regulation of cytosolic calcium ion concentrationGO:00072041220.017
pancreatic stellate cell proliferationGO:007234320.017
positive regulation of neurogenesisGO:00507691650.017
cellular component morphogenesisGO:00329891550.017
amino acid transportGO:0006865700.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
reproductive processGO:00224143720.017
positive regulation of protein phosphorylationGO:00019341350.017
rhythmic processGO:00485111560.017
negative regulation of growthGO:0045926370.017
metal ion homeostasisGO:00550651860.017
anion transportGO:00068201780.017
macromolecular complex assemblyGO:00650032730.017
developmental process involved in reproductionGO:00030061590.017
cell cell signalingGO:00072673350.017
embryo developmentGO:0009790490.017
cardiovascular system developmentGO:00723581340.017
response to cytokineGO:00340972150.017
reproductionGO:00000032450.017
amine metabolic processGO:0009308380.016
cellular response to oxygen containing compoundGO:19017013860.016
organelle organizationGO:00069962660.016
peptidyl amino acid modificationGO:00181931260.016
cellular response to growth factor stimulusGO:00713631620.016
cell morphogenesis involved in differentiationGO:00009041190.016
behaviorGO:00076102050.016
regulation of intracellular signal transductionGO:19025312180.016
positive regulation of cell deathGO:00109421840.016
regulation of sodium ion transmembrane transporter activityGO:200064940.016
circadian rhythmGO:0007623880.016
s shaped body morphogenesisGO:007205020.016
comma shaped body morphogenesisGO:007204920.016
coronary vasculature morphogenesisGO:006097730.016
myeloid leukocyte differentiationGO:0002573200.015
purine nucleotide metabolic processGO:00061632290.015
positive regulation of protein metabolic processGO:00512471780.015
ion transmembrane transportGO:00342203650.015
monocarboxylic acid transportGO:0015718520.015
tube formationGO:003514830.015
potassium ion transmembrane transportGO:0071805710.015
signal transduction by phosphorylationGO:00230141440.015
response to estradiolGO:00323551640.015
protein oligomerizationGO:00512591910.015
intracellular signal transductionGO:00355563140.015
multicellular organism reproductionGO:00325042330.015
hexose metabolic processGO:0019318580.015
negative regulation of transcription regulatory region dna bindingGO:200067820.015
inorganic cation transmembrane transportGO:00986622020.015
organic hydroxy compound metabolic processGO:19016151150.014
vitamin d receptor signaling pathwayGO:007056110.014
ribose phosphate metabolic processGO:00196932350.014
intracellular receptor signaling pathwayGO:0030522350.014
smooth muscle cell proliferationGO:0048659770.014
tissue morphogenesisGO:0048729220.014
muscle cell proliferationGO:0033002840.014
muscle tissue morphogenesisGO:006041510.014
immune system processGO:00023762040.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
positive regulation of phagocytosis engulfmentGO:006010040.014
adult locomotory behaviorGO:000834440.014
positive regulation of mapk cascadeGO:0043410920.014
nucleotide metabolic processGO:00091172790.014
hair cell differentiationGO:003531520.014
locomotionGO:00400112370.014
heart developmentGO:0007507720.014
cellular catabolic processGO:00442482950.013
gonad developmentGO:00084061040.013
dendrite developmentGO:0016358720.013
locomotor rhythmGO:004547510.013
positive regulation of catalytic activityGO:00430851840.013
response to alkaloidGO:00432791320.013
urogenital system developmentGO:0001655780.013
negative regulation of transportGO:00510511360.013
regulation of system processGO:00440572080.013
single organism behaviorGO:00447081300.013
regenerationGO:00310991630.013
retina morphogenesis in camera type eyeGO:006004210.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
regulation of cellular amine metabolic processGO:003323880.013
muscle contractionGO:0006936880.013
embryonic skeletal system morphogenesisGO:004870430.013
regulation of transcription regulatory region dna bindingGO:200067740.013
cellular cation homeostasisGO:00300031800.013
epithelial cell proliferationGO:0050673540.012
organic acid metabolic processGO:00060822920.012
regulation of fat cell proliferationGO:007034410.012
cellular response to abiotic stimulusGO:0071214850.012
dendrite morphogenesisGO:0048813430.012
amide transportGO:00428861050.012
cellular response to external stimulusGO:00714961180.012
multi organism reproductive processGO:00447032620.012
regulation of growthGO:00400081050.012
ventral spinal cord developmentGO:002151730.012
regulation of endocytosisGO:0030100420.012
regulation of neuron deathGO:19012141150.012
negative regulation of signalingGO:00230571570.012
cellular amine metabolic processGO:0044106380.012
regulation of protein phosphorylationGO:00019321830.012
angiogenesis involved in coronary vascular morphogenesisGO:006097830.012
growthGO:00400071650.012
regulation of leukocyte differentiationGO:1902105200.012
regulation of lipid metabolic processGO:0019216680.012
oxoacid metabolic processGO:00434362900.012
camera type eye morphogenesisGO:004859320.012
cellular response to reactive oxygen speciesGO:0034614550.011
monosaccharide metabolic processGO:0005996610.011
response to monosaccharideGO:00342841590.011
neuron fate commitmentGO:004866340.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
regulation of pancreatic stellate cell proliferationGO:200022920.011
positive regulation of neuron projection developmentGO:0010976990.011
organ formationGO:004864530.011
positive regulation of transportGO:00510502450.011
inner ear morphogenesisGO:004247210.011
transmembrane transportGO:00550854120.011
multicellular organismal homeostasisGO:0048871490.011
negative regulation of molecular functionGO:00440921330.011
negative regulation of collagen biosynthetic processGO:003296640.011
heart morphogenesisGO:000300730.011
leukocyte proliferationGO:0070661290.011
regulation of phagocytosis engulfmentGO:006009940.011
carbohydrate derivative biosynthetic processGO:19011371240.011
regulation of response to external stimulusGO:00321011060.011
regulation of protein modification processGO:00313991940.011
embryonic pattern specificationGO:000988010.011
regulation of secretion by cellGO:19035302080.011
regulation of metal ion transportGO:00109591180.011
regulation of cell cycleGO:0051726730.011
nucleotide biosynthetic processGO:0009165980.011
lung developmentGO:0030324430.011
reproductive structure developmentGO:00486081280.011
head developmentGO:00603222470.011
regulation of cellular ketone metabolic processGO:0010565270.011
respiratory tube developmentGO:0030323430.011
positive regulation of protein modification processGO:00314011420.011
single organism catabolic processGO:00447122830.011
epithelial tube formationGO:007217530.011
response to hexoseGO:00097461440.011
lipid biosynthetic processGO:00086101280.010
positive regulation of apoptotic processGO:00430651540.010
glucose homeostasisGO:0042593750.010
positive regulation of transferase activityGO:0051347810.010
sterol homeostasisGO:005509230.010
glycosyl compound metabolic processGO:19016571820.010
mitotic cell cycleGO:0000278490.010
negative regulation of cell developmentGO:0010721820.010
negative regulation of cell growthGO:0030308330.010
positive regulation of endocytosisGO:0045807280.010
response to reactive oxygen speciesGO:00003021200.010
metal ion transportGO:00300012890.010
response to glucoseGO:00097491360.010
regulation of kinase activityGO:00435491170.010
wound healingGO:00420601220.010
kidney developmentGO:0001822670.010
response to nicotineGO:0035094510.010
regulation of cellular amino acid metabolic processGO:000652120.010
purine nucleoside metabolic processGO:00422781690.010
auditory receptor cell differentiationGO:004249120.010
hematopoietic progenitor cell differentiationGO:000224420.010
organ inductionGO:000175910.010
cellular response to cytokine stimulusGO:00713451270.010

Sost disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
sensory system diseaseDOID:005015500.057
nervous system diseaseDOID:86300.057
eye and adnexa diseaseDOID:149200.027
retinal degenerationDOID:846600.027
retinitis pigmentosaDOID:1058400.027
eye diseaseDOID:561400.027
retinal diseaseDOID:567900.027
cardiovascular system diseaseDOID:128700.019
muscle tissue diseaseDOID:6600.017
heart diseaseDOID:11400.017
muscular diseaseDOID:008000000.017
myopathyDOID:42300.017
musculoskeletal system diseaseDOID:1700.017
cardiomyopathyDOID:005070000.017