Rattus norvegicus

108 known processes

Pde3a

phosphodiesterase 3A, cGMP inhibited

(Aliases: RNPDE3A)

Pde3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of secretionGO:00510471400.621
positive regulation of signalingGO:00230562700.555
cell migrationGO:00164771970.513
cation transportGO:00068123820.507
regulation of ion transportGO:00432692450.491
regulation of secretionGO:00510462240.473
Rat
regulation of cellular localizationGO:00603412630.466
Rat
positive regulation of multicellular organismal processGO:00512403870.460
Mouse
response to molecule of bacterial originGO:00022371940.441
neurological system processGO:00508772190.395
intracellular signal transductionGO:00355563140.382
Human
cell cell signalingGO:00072673350.369
Rat
response to other organismGO:00517072200.313
protein localizationGO:00081041910.296
immune system processGO:00023762040.278
positive regulation of transportGO:00510502450.267
positive regulation of cell communicationGO:00106472710.265
regulation of cellular protein metabolic processGO:00322682670.246
reproductive processGO:00224143720.242
cell motilityGO:00488702020.228
response to bacteriumGO:00096172000.228
sensory perceptionGO:00076001010.225
positive regulation of secretion by cellGO:19035321280.225
positive regulation of locomotionGO:00400171020.223
negative regulation of response to stimulusGO:00485851550.216
regulation of locomotionGO:00400121480.214
positive regulation of response to stimulusGO:00485842850.207
immune responseGO:00069551040.207
positive regulation of nervous system developmentGO:00519621780.199
response to ethanolGO:00454711620.190
positive regulation of cell motilityGO:2000147970.184
signal releaseGO:00230611450.175
Rat
positive regulation of intracellular signal transductionGO:19025331380.171
lipid biosynthetic processGO:00086101280.170
regulation of molecular functionGO:00650093980.169
regulation of synaptic transmissionGO:00508041410.169
single organism behaviorGO:00447081300.166
cellular response to cytokine stimulusGO:00713451270.165
regulation of nervous system developmentGO:00519602640.165
regulation of hormone secretionGO:00468831060.165
Rat
secretion by cellGO:00329402480.163
Rat
regulation of metal ion transportGO:00109591180.159
regulation of secretion by cellGO:19035302080.154
Rat
cellular response to endogenous stimulusGO:00714953770.149
Human
reproductive system developmentGO:00614581280.148
positive regulation of protein metabolic processGO:00512471780.146
cellular component movementGO:00069282480.137
protein phosphorylationGO:00064683450.136
transcription dna templatedGO:00063513770.136
response to lipopolysaccharideGO:00324961910.135
synaptic transmissionGO:00072682350.135
positive regulation of phosphorylationGO:00423271770.134
reproductionGO:00000032450.134
chemical homeostasisGO:00488782920.133
regulation of exocytosisGO:0017157370.132
regulation of phosphorus metabolic processGO:00511743490.129
muscle contractionGO:0006936880.126
immune effector processGO:0002252530.126
regulation of phosphorylationGO:00423252480.124
organic hydroxy compound metabolic processGO:19016151150.123
response to woundingGO:00096112540.123
regulation of cell differentiationGO:00455953200.121
Mouse
signal transduction by phosphorylationGO:00230141440.120
regulation of rna metabolic processGO:00512523910.120
response to estrogenGO:00436272320.119
neuron developmentGO:00486662860.116
multicellular organism reproductionGO:00325042330.114
hormone secretionGO:00468791150.111
Rat
positive regulation of phosphorus metabolic processGO:00105622620.111
regulation of protein phosphorylationGO:00019321830.110
regulation of immune system processGO:00026821230.110
positive regulation of cellular protein metabolic processGO:00322701670.109
regulation of hormone levelsGO:00108171870.107
Rat
apoptotic processGO:00069153810.106
positive regulation of neurogenesisGO:00507691650.106
regulation of neuron deathGO:19012141150.105
regulation of anatomical structure morphogenesisGO:00226031410.103
regulation of phosphate metabolic processGO:00192203490.100
sensory perception of painGO:0019233730.098
transcription from rna polymerase ii promoterGO:00063662520.098
g protein coupled receptor signaling pathwayGO:00071862420.096
organic substance catabolic processGO:19015753160.096
response to biotic stimulusGO:00096072260.094
lipid metabolic processGO:00066292830.093
positive regulation of cell differentiationGO:00455972170.090
Mouse
response to nutrient levelsGO:00316673700.090
positive regulation of cellular component movementGO:00512721020.089
response to carbohydrateGO:00097431830.089
positive regulation of immune system processGO:0002684900.088
localization of cellGO:00516742020.088
divalent metal ion transportGO:00708381320.088
positive regulation of cell developmentGO:00107201760.087
Mouse
regulation of intracellular signal transductionGO:19025312180.085
regulation of immunoglobulin productionGO:000263740.085
multicellular organismal reproductive processGO:00486092330.085
response to transforming growth factor betaGO:0071559460.084
Human
multi organism reproductive processGO:00447032620.083
regulation of anatomical structure sizeGO:00900661350.081
amine metabolic processGO:0009308380.081
developmental inductionGO:003112820.080
regulation of peptide secretionGO:0002791820.080
Rat
macromolecule localizationGO:00330362520.080
regulation of apoptotic processGO:00429813350.079
peptide hormone secretionGO:0030072840.079
Rat
regulation of neurogenesisGO:00507672470.079
acid secretionGO:0046717480.077
nitrogen compound transportGO:00717052290.077
Rat
erk1 and erk2 cascadeGO:0070371480.077
response to organophosphorusGO:00466831020.076
regulation of cellular component movementGO:00512701500.076
single organism reproductive processGO:00447022970.074
regulation of protein metabolic processGO:00512462890.074
ion homeostasisGO:00508012120.073
positive regulation of cell migrationGO:0030335960.071
lymphocyte activationGO:0046649430.071
insulin secretionGO:0030073690.070
Rat
response to nicotineGO:0035094510.070
response to extracellular stimulusGO:00099913800.070
membrane organizationGO:0061024940.069
hormone transportGO:00099141210.069
Rat
locomotionGO:00400112370.069
cell type specific apoptotic processGO:00972851340.069
sex differentiationGO:00075481130.068
neuropeptide signaling pathwayGO:0007218290.067
regulation of peptide hormone secretionGO:0090276800.067
Rat
leukocyte activation involved in immune responseGO:0002366160.067
positive regulation of phosphate metabolic processGO:00459372620.067
response to external biotic stimulusGO:00432072210.065
nucleic acid templated transcriptionGO:00976593790.064
regulation of homeostatic processGO:00328441010.064
phasic smooth muscle contractionGO:001482130.064
secretionGO:00469033070.064
Rat
response to growth factorGO:00708481890.064
Human
muscle system processGO:00030121150.063
homeostatic processGO:00425923310.063
regulation of transmembrane transportGO:00347621220.063
cellular response to organic cyclic compoundGO:00714072020.062
Human
cellular component biogenesisGO:00440853680.061
positive regulation of developmental processGO:00510942830.060
Mouse
organic hydroxy compound biosynthetic processGO:1901617510.060
cellular response to hormone stimulusGO:00328702470.060
cellular divalent inorganic cation homeostasisGO:00725031620.060
neuron deathGO:00709971270.059
regulation of programmed cell deathGO:00430673410.059
monocarboxylic acid metabolic processGO:00327871520.059
regulation of blood vessel sizeGO:0050880890.058
response to alkaloidGO:00432791320.058
mapk cascadeGO:00001651400.058
regulation of rna biosynthetic processGO:20011413810.058
positive regulation of signal transductionGO:00099671750.056
rna metabolic processGO:00160704060.056
negative regulation of signalingGO:00230571570.056
Rat
regulation of signal transductionGO:00099663180.056
response to decreased oxygen levelsGO:00362932370.056
vascular process in circulatory systemGO:0003018960.055
Human
response to peptide hormoneGO:00434342780.055
development of primary sexual characteristicsGO:00451371070.055
second messenger mediated signalingGO:0019932510.055
Human
positive regulation of molecular functionGO:00440932300.054
divalent inorganic cation transportGO:00725111340.053
cation transmembrane transportGO:00986552630.053
circulatory system processGO:00030131830.053
Human
calcium ion transportGO:00068161310.053
cellular metal ion homeostasisGO:00068751720.052
programmed cell deathGO:00125013920.052
female pregnancyGO:00075651220.051
organophosphate metabolic processGO:00196373700.051
regulation of membrane potentialGO:00423911100.051
biological adhesionGO:00226101100.050
regulation of organ formationGO:000315620.049
metal ion transportGO:00300012890.049
cellular amine metabolic processGO:0044106380.049
small molecule biosynthetic processGO:00442831240.049
neuron projection developmentGO:00311752730.049
neuron differentiationGO:00301823680.049
cell projection morphogenesisGO:00488581230.048
amine transportGO:0015837570.048
single organism intracellular transportGO:19025821660.048
reproductive structure developmentGO:00486081280.048
regulation of kinase activityGO:00435491170.048
calcium mediated signalingGO:0019722230.048
gonad developmentGO:00084061040.047
regulation of ion transmembrane transportGO:00347651210.047
negative regulation of cell deathGO:00605482290.047
regulation of tube sizeGO:0035150890.047
carboxylic acid metabolic processGO:00197522890.046
regulation of calcium ion transportGO:0051924770.045
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.045
behaviorGO:00076102050.045
organic anion transportGO:00157111320.044
cellular response to steroid hormone stimulusGO:0071383930.044
response to cocaineGO:0042220390.043
transmembrane transportGO:00550854120.043
cardiovascular system developmentGO:00723581340.043
regulation of vesicle mediated transportGO:0060627810.043
positive regulation of mapk cascadeGO:0043410920.042
axon developmentGO:0061564960.042
myeloid leukocyte differentiationGO:0002573200.042
response to oxygen levelsGO:00704822650.042
positive regulation of blood circulationGO:1903524650.042
regulation of cell developmentGO:00602842630.041
Mouse
cell projection organizationGO:00300303020.041
positive regulation of protein modification processGO:00314011420.041
developmental process involved in reproductionGO:00030061590.041
cellular ketone metabolic processGO:0042180510.041
establishment of protein localizationGO:00451841410.040
positive regulation of gene expressionGO:00106282440.040
central nervous system developmentGO:00074173110.040
response to ketoneGO:19016541820.040
ossificationGO:0001503700.040
leukocyte mediated immunityGO:0002443280.039
leukocyte differentiationGO:0002521300.039
ion transmembrane transportGO:00342203650.039
regulation of response to stressGO:00801341260.039
negative regulation of metabolic processGO:00098923310.039
single organism carbohydrate metabolic processGO:00447231180.039
metal ion homeostasisGO:00550651860.039
organ inductionGO:000175910.038
gamete generationGO:00072761240.038
regulation of mapk cascadeGO:00434081160.038
alcohol biosynthetic processGO:0046165380.037
regulation of multicellular organismal developmentGO:20000263760.037
vesicle mediated transportGO:00161921810.037
cellular response to glucocorticoid stimulusGO:0071385680.037
protein transportGO:00150311320.036
positive regulation of biosynthetic processGO:00098913190.036
positive regulation of kinase activityGO:0033674770.036
single organism biosynthetic processGO:00447113420.036
cellular protein localizationGO:00346131220.036
positive regulation of synaptic transmissionGO:0050806620.036
positive regulation of cytosolic calcium ion concentrationGO:00072041220.035
protein complex biogenesisGO:00702712630.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
learning or memoryGO:0007611900.035
regulation of protein modification processGO:00313991940.035
steroid biosynthetic processGO:0006694480.034
response to metal ionGO:00100382530.034
cellular ion homeostasisGO:00068731840.034
cellular cation homeostasisGO:00300031800.034
negative regulation of transportGO:00510511360.034
Rat
cognitionGO:0050890920.034
response to inorganic substanceGO:00100353770.034
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.034
negative regulation of neuron deathGO:1901215690.034
cellular homeostasisGO:00197252520.034
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.033
inorganic cation transmembrane transportGO:00986622020.033
response to campGO:0051591910.033
single organism cellular localizationGO:19025801020.033
defense responseGO:00069521940.033
negative regulation of programmed cell deathGO:00430691830.033
regulation of transferase activityGO:00513381230.033
positive regulation of cellular component organizationGO:00511302000.033
regulation of peptide transportGO:0090087870.033
Rat
macromolecular complex subunit organizationGO:00439333390.032
circulatory system developmentGO:00723591340.032
regulation of cell motilityGO:20001451310.032
cellular response to stressGO:00335542690.032
positive regulation of hormone secretionGO:0046887650.032
regulation of catalytic activityGO:00507903040.032
response to estradiolGO:00323551640.032
positive regulation of neuron differentiationGO:00456661260.032
sequestering of calcium ionGO:005120880.032
response to hypoxiaGO:00016662310.032
calcium ion homeostasisGO:00550741620.032
glial cell differentiationGO:0010001650.031
response to xenobiotic stimulusGO:0009410230.031
regulation of cell proliferationGO:00421273590.031
cellular component assemblyGO:00226073600.031
protein complex assemblyGO:00064612630.031
positive regulation of protein phosphorylationGO:00019341350.031
tumor necrosis factor biosynthetic processGO:004253310.031
cellular chemical homeostasisGO:00550822470.030
protein complex subunit organizationGO:00718223020.030
organic acid metabolic processGO:00060822920.030
negative regulation of ion transmembrane transportGO:0034766160.030
positive regulation of leukocyte degranulationGO:004330240.030
negative regulation of secretion by cellGO:1903531720.030
Rat
female sex differentiationGO:0046660590.030
response to insulinGO:00328681330.030
positive regulation of transferase activityGO:0051347810.029
negative regulation of response to external stimulusGO:0032102370.029
positive regulation of immune responseGO:0050778420.029
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.029
alcohol metabolic processGO:0006066770.029
carbohydrate metabolic processGO:00059751300.029
response to hexoseGO:00097461440.029
regulation of transcription from rna polymerase ii promoterGO:00063572340.029
negative regulation of apoptotic processGO:00430661810.029
inorganic ion transmembrane transportGO:00986602290.029
hematopoietic or lymphoid organ developmentGO:0048534360.029
regulation of leukocyte mediated immunityGO:0002703190.029
organophosphate biosynthetic processGO:00904071430.029
regulation of mononuclear cell proliferationGO:0032944260.029
regulation of cellular ketone metabolic processGO:0010565270.028
regulation of cellular amine metabolic processGO:003323880.028
cell morphogenesis involved in neuron differentiationGO:00486671060.028
blood circulationGO:00080151830.027
Human
dephosphorylationGO:0016311980.027
cellular response to transforming growth factor beta stimulusGO:0071560410.027
Human
digestive system developmentGO:0055123410.027
neurotransmitter transportGO:0006836420.027
regulation of insulin secretionGO:0050796650.027
Rat
multi multicellular organism processGO:00447061380.027
acute inflammatory responseGO:0002526580.027
negative regulation of ion transportGO:0043271510.027
wound healingGO:00420601220.027
positive regulation of macromolecule biosynthetic processGO:00105572470.027
positive regulation of cell deathGO:00109421840.027
positive regulation of peptide secretionGO:0002793520.026
sensory organ developmentGO:0007423740.026
positive regulation of cellular biosynthetic processGO:00313282950.026
positive regulation of homeostatic processGO:0032846490.026
positive regulation of exocytosisGO:0045921190.026
exocytosisGO:0006887600.026
regulation of response to external stimulusGO:00321011060.026
regulation of lipid metabolic processGO:0019216680.026
cell morphogenesisGO:00009021420.026
jak stat cascadeGO:0007259260.025
phospholipid metabolic processGO:0006644610.025
response to toxic substanceGO:00096361330.025
intracellular protein transportGO:0006886790.025
response to foodGO:0032094270.025
macromolecular complex assemblyGO:00650032730.025
negative regulation of nervous system developmentGO:0051961790.025
regulation of protein kinase activityGO:00458591050.025
negative regulation of response to woundingGO:1903035230.024
negative regulation of macromolecule metabolic processGO:00106052600.024
negative regulation of chronic inflammatory responseGO:000267720.024
regulation of defecationGO:200029210.024
glucose homeostasisGO:0042593750.024
glycerolipid metabolic processGO:0046486670.024
brain developmentGO:00074202470.023
cellular response to corticosteroid stimulusGO:0071384690.023
regulation of pancreatic stellate cell proliferationGO:200022920.023
regulation of neuron differentiationGO:00456642080.023
regulation of immune effector processGO:0002697320.023
cytosolic calcium ion homeostasisGO:00514801400.023
divalent inorganic cation homeostasisGO:00725071650.023
oxoacid metabolic processGO:00434362900.023
positive regulation of cellular component biogenesisGO:0044089550.023
cellular macromolecule localizationGO:00707271220.023
negative regulation of biosynthetic processGO:00098901680.023
epithelium developmentGO:0060429960.023
visual learningGO:000854280.023
organ formationGO:004864530.023
response to nutrientGO:00075842480.023
regulation of transcription dna templatedGO:00063553740.023
intracellular transportGO:00469071850.022
hemopoiesisGO:0030097340.022
regulation of sodium ion transmembrane transporter activityGO:200064940.022
cell morphogenesis involved in differentiationGO:00009041190.022
single organism membrane organizationGO:0044802740.022
rna biosynthetic processGO:00327743800.022
single organism organelle organizationGO:19025891800.022
peptide secretionGO:0002790860.022
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.022
response to monosaccharideGO:00342841590.021
peptidyl tyrosine phosphorylationGO:0018108720.021
sexual reproductionGO:00199531480.021
positive regulation of catalytic activityGO:00430851840.021
immune system developmentGO:0002520410.021
regulation of ion transmembrane transporter activityGO:0032412480.021
gamma aminobutyric acid transportGO:001581280.021
organelle organizationGO:00069962660.021
Mouse
negative regulation of homeostatic processGO:0032845470.021
cell part morphogenesisGO:00329901230.021
response to glucocorticoidGO:00513842230.021
amide transportGO:00428861050.020
Rat
regulation of response to woundingGO:1903034690.020
digestive tract developmentGO:0048565390.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
regulation of neurological system processGO:0031644430.020
positive regulation of transcription dna templatedGO:00458931970.020
regulation of cellular component organizationGO:00511283680.020
Mouse
regulation of cellular amino acid metabolic processGO:000652120.020
inflammatory responseGO:00069541500.020
ras protein signal transductionGO:0007265290.020
regulation of catabolic processGO:00098941130.020
negative regulation of multicellular organismal processGO:00512412030.020
reactive nitrogen species metabolic processGO:200105710.020
head developmentGO:00603222470.019
regulation of transmembrane transporter activityGO:0022898490.019
ovulation cycle processGO:0022602500.019
cellular response to peptideGO:19016531330.019
synaptic transmission cholinergicGO:0007271110.019
enzyme linked receptor protein signaling pathwayGO:00071671160.019
positive regulation of cell proliferationGO:00082842490.019
regulation of sensory perceptionGO:0051931290.019
taxisGO:0042330670.019
growthGO:00400071650.019
negative regulation of neuron differentiationGO:0045665620.019
regulation of transporter activityGO:0032409500.018
regulation of epithelial cell proliferationGO:0050678490.018
memoryGO:0007613540.018
choline transportGO:001587140.018
anatomical structure morphogenesisGO:00096532980.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
heterocycle catabolic processGO:00467001670.018
regulation of erk1 and erk2 cascadeGO:0070372410.018
cellular response to oxygen levelsGO:0071453600.018
response to purine containing compoundGO:00140741260.018
myeloid cell differentiationGO:0030099220.018
positive regulation of leukocyte activationGO:0002696300.018
cellular carbohydrate metabolic processGO:0044262720.018
immunoglobulin mediated immune responseGO:001606440.018
peptide transportGO:0015833970.018
Rat
response to oxidative stressGO:00069791860.018
vasoconstrictionGO:0042310540.018
negative regulation of cellular metabolic processGO:00313242810.018
regulation of organic acid transportGO:0032890350.018
tube developmentGO:0035295890.018
sarcoplasmic reticulum calcium ion transportGO:007029680.018
cytokine productionGO:0001816610.017
small gtpase mediated signal transductionGO:0007264360.017
regulation of amine transportGO:0051952540.017
positive regulation of cell projection organizationGO:00313461110.017
endoplasmic reticulum to cytosol transportGO:190351340.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
positive regulation of insulin secretionGO:0032024360.017
macromolecule catabolic processGO:0009057580.017
cellular response to nitrogen compoundGO:19016992100.017
Human
myeloid cell activation involved in immune responseGO:0002275130.017
synaptic transmission glutamatergicGO:0035249330.017
development of primary female sexual characteristicsGO:0046545560.017
cellular amino acid metabolic processGO:00065201070.017
response to painGO:0048265110.017
regulation of organelle organizationGO:0033043800.016
Mouse
steroid metabolic processGO:0008202730.016
agingGO:00075682410.016
male sex differentiationGO:0046661640.016
male gamete generationGO:0048232990.016
regulation of system processGO:00440572080.016
cellular response to oxygen containing compoundGO:19017013860.016
Human
peptidyl tyrosine modificationGO:0018212720.016
cellular response to lipidGO:00713962010.016
regulation of neuron apoptotic processGO:0043523830.016
regulation of ion homeostasisGO:2000021630.016
carbohydrate homeostasisGO:0033500750.016
cytokine biosynthetic processGO:004208930.016
negative regulation of molecular functionGO:00440921330.016
regulation of cell morphogenesisGO:0022604770.016
cytoskeleton organizationGO:00070101110.016
neuron apoptotic processGO:0051402880.016
response to glucoseGO:00097491360.016
positive regulation of cellular amine metabolic processGO:003324030.016
regulation of cytokine biosynthetic processGO:004203530.015
regulation of neuron projection developmentGO:00109751610.015
response to ammonium ionGO:0060359710.015
negative regulation of cell differentiationGO:0045596990.015
carbohydrate derivative metabolic processGO:19011353460.015
male gonad developmentGO:0008584590.015
positive regulation of response to foodGO:003209730.015
catabolic processGO:00090563510.015
cellular biogenic amine metabolic processGO:0006576300.015
regulation of developmental growthGO:0048638450.015
negative regulation of calcium ion importGO:009028120.015
regulation of protein catabolic processGO:0042176160.015
adult locomotory behaviorGO:000834440.015
negative regulation of neurogenesisGO:0050768780.015
dendrite developmentGO:0016358720.015
spermatogenesisGO:0007283990.015
regulation of cell adhesionGO:0030155520.014
regulation of intracellular transportGO:0032386650.014
regulation of muscle contractionGO:0006937530.014
hormone biosynthetic processGO:0042446250.014
regulation of leukocyte degranulationGO:004330060.014
learningGO:0007612330.014
tolerance induction dependent upon immune responseGO:000246120.014
hair cell differentiationGO:003531520.014
regulation of cellular component biogenesisGO:0044087860.014
positive regulation of peptide hormone secretionGO:0090277500.014
response to radiationGO:00093141370.014
rho protein signal transductionGO:0007266110.014
innate immune responseGO:0045087350.014
organic hydroxy compound transportGO:0015850770.014
cell cell signaling involved in cell fate commitmentGO:004516820.014
positive regulation of epithelial cell proliferationGO:0050679320.014
regulation of cation channel activityGO:2001257230.014
insecticide metabolic processGO:001714340.014
regulation of actin filament based processGO:0032970420.014
regulation of cell migrationGO:00303341280.014
single organism cell adhesionGO:0098602460.014
monoamine transportGO:0015844430.014
regulation of sensory perception of painGO:0051930290.013
reactive oxygen species metabolic processGO:0072593370.013
negative regulation of cell communicationGO:00106481580.013
Rat
regulation of cell projection organizationGO:00313441750.013
protein oligomerizationGO:00512591910.013
positive regulation of apoptotic processGO:00430651540.013
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.013

Pde3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.027
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
central nervous system diseaseDOID:33100.020
disease of cellular proliferationDOID:1456600.015