Rattus norvegicus

107 known processes

Pde3b

phosphodiesterase 3B, cGMP-inhibited

Pde3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription dna templatedGO:00063513770.154
regulation of rna biosynthetic processGO:20011413810.114
rna biosynthetic processGO:00327743800.114
rna metabolic processGO:00160704060.112
catabolic processGO:00090563510.105
secretionGO:00469033070.092
nitrogen compound transportGO:00717052290.088
organophosphate metabolic processGO:00196373700.087
response to extracellular stimulusGO:00099913800.084
response to nutrientGO:00075842480.083
regulation of rna metabolic processGO:00512523910.082
neuron developmentGO:00486662860.078
anatomical structure morphogenesisGO:00096532980.077
Human
cellular component movementGO:00069282480.075
positive regulation of transportGO:00510502450.074
regulation of phosphate metabolic processGO:00192203490.071
response to nutrient levelsGO:00316673700.071
carboxylic acid metabolic processGO:00197522890.070
cellular catabolic processGO:00442482950.069
positive regulation of signalingGO:00230562700.064
negative regulation of macromolecule metabolic processGO:00106052600.063
tissue developmentGO:00098882520.063
regulation of ion transportGO:00432692450.061
cellular response to oxygen containing compoundGO:19017013860.059
Mouse
cell morphogenesis involved in differentiationGO:00009041190.059
single organism catabolic processGO:00447122830.058
nucleoside phosphate metabolic processGO:00067532830.057
nucleobase containing small molecule metabolic processGO:00550863160.057
single organism reproductive processGO:00447022970.056
Rat
regulation of molecular functionGO:00650093980.054
negative regulation of metabolic processGO:00098923310.053
Human
ribose phosphate metabolic processGO:00196932350.052
organic acid metabolic processGO:00060822920.051
cellular response to endogenous stimulusGO:00714953770.051
Mouse
brain developmentGO:00074202470.051
locomotionGO:00400112370.051
regulation of intracellular signal transductionGO:19025312180.051
aromatic compound catabolic processGO:00194391680.050
regulation of signal transductionGO:00099663180.050
heterocycle catabolic processGO:00467001670.049
cellular component assemblyGO:00226073600.049
regulation of phosphorus metabolic processGO:00511743490.048
regulation of nucleic acid templated transcriptionGO:19035063800.048
positive regulation of nitrogen compound metabolic processGO:00511733340.048
negative regulation of cell deathGO:00605482290.047
Rat
purine containing compound metabolic processGO:00725212530.045
regulation of secretionGO:00510462240.043
anion transportGO:00068201780.043
positive regulation of biosynthetic processGO:00098913190.042
regulation of cell proliferationGO:00421273590.042
positive regulation of cell deathGO:00109421840.042
purine nucleoside metabolic processGO:00422781690.042
oxoacid metabolic processGO:00434362900.041
cellular response to peptideGO:19016531330.041
Mouse
purine ribonucleoside metabolic processGO:00461281680.040
organic cyclic compound catabolic processGO:19013611750.040
transmembrane transportGO:00550854120.040
positive regulation of cell proliferationGO:00082842490.039
intracellular signal transductionGO:00355563140.039
ribonucleotide catabolic processGO:00092611360.039
response to corticosteroidGO:00319602350.039
purine nucleotide catabolic processGO:00061951360.038
nucleotide metabolic processGO:00091172790.038
organophosphate catabolic processGO:00464341480.038
cation transportGO:00068123820.038
cellular amino acid metabolic processGO:00065201070.038
response to growth factorGO:00708481890.038
response to inorganic substanceGO:00100353770.037
central nervous system developmentGO:00074173110.037
chemical homeostasisGO:00488782920.037
Mouse
regulation of transcription dna templatedGO:00063553740.037
single organism biosynthetic processGO:00447113420.037
protein complex assemblyGO:00064612630.037
cellular component biogenesisGO:00440853680.036
neuron differentiationGO:00301823680.036
homeostatic processGO:00425923310.036
Mouse
neuron projection developmentGO:00311752730.035
nucleic acid templated transcriptionGO:00976593790.035
purine nucleotide metabolic processGO:00061632290.035
agingGO:00075682410.035
divalent metal ion transportGO:00708381320.035
ion transmembrane transportGO:00342203650.035
regulation of protein metabolic processGO:00512462890.035
ribonucleotide metabolic processGO:00092592310.035
secretion by cellGO:00329402480.035
cellular nitrogen compound catabolic processGO:00442701630.034
response to estrogenGO:00436272320.034
positive regulation of phosphate metabolic processGO:00459372620.034
positive regulation of gene expressionGO:00106282440.034
purine nucleoside triphosphate metabolic processGO:00091441410.034
purine ribonucleoside triphosphate catabolic processGO:00092071220.034
response to acid chemicalGO:00011012220.033
positive regulation of cellular biosynthetic processGO:00313282950.033
ribonucleoside triphosphate metabolic processGO:00091991410.033
cell projection organizationGO:00300303020.033
positive regulation of developmental processGO:00510942830.033
nucleoside triphosphate catabolic processGO:00091431230.033
nucleotide catabolic processGO:00091661390.033
cellular ketone metabolic processGO:0042180510.032
multi organism reproductive processGO:00447032620.032
Rat
regulation of cellular protein metabolic processGO:00322682670.032
cellular response to peptide hormone stimulusGO:00713751200.031
Mouse
purine ribonucleotide catabolic processGO:00091541360.031
carbohydrate derivative metabolic processGO:19011353460.031
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
organic substance catabolic processGO:19015753160.030
regulation of apoptotic processGO:00429813350.030
Rat
cell projection morphogenesisGO:00488581230.030
reproductionGO:00000032450.029
Rat
cellular response to organonitrogen compoundGO:00714171970.029
Mouse
regulation of cellular ketone metabolic processGO:0010565270.029
cellular chemical homeostasisGO:00550822470.029
cellular cation homeostasisGO:00300031800.029
response to mechanical stimulusGO:00096121340.029
carbohydrate derivative catabolic processGO:19011361470.029
positive regulation of cell communicationGO:00106472710.029
glycosyl compound catabolic processGO:19016581260.029
positive regulation of cellular protein metabolic processGO:00322701670.029
positive regulation of multicellular organismal processGO:00512403870.029
positive regulation of rna biosynthetic processGO:19026801970.028
defense responseGO:00069521940.028
positive regulation of rna metabolic processGO:00512542030.028
sensory perceptionGO:00076001010.028
purine ribonucleoside catabolic processGO:00461301240.028
negative regulation of cellular metabolic processGO:00313242810.028
positive regulation of cellular component organizationGO:00511302000.027
organelle organizationGO:00069962660.027
regulation of transcription from rna polymerase ii promoterGO:00063572340.027
monocarboxylic acid metabolic processGO:00327871520.027
glycosyl compound metabolic processGO:19016571820.027
cell motilityGO:00488702020.027
regulation of cell developmentGO:00602842630.027
positive regulation of secretion by cellGO:19035321280.027
response to glucocorticoidGO:00513842230.027
neuron projection morphogenesisGO:00488121220.027
regulation of multicellular organismal developmentGO:20000263760.026
Human
regulation of neuron differentiationGO:00456642080.026
ribonucleoside triphosphate catabolic processGO:00092031220.026
calcium ion homeostasisGO:00550741620.026
nucleoside phosphate catabolic processGO:19012921400.026
negative regulation of apoptotic processGO:00430661810.026
Rat
regulation of cell differentiationGO:00455953200.026
macromolecular complex assemblyGO:00650032730.026
ribonucleoside metabolic processGO:00091191740.026
endocytosisGO:0006897840.026
urogenital system developmentGO:0001655780.025
cellular metal ion homeostasisGO:00068751720.025
metal ion transportGO:00300012890.025
circulatory system developmentGO:00723591340.025
Human
carbohydrate metabolic processGO:00059751300.025
purine nucleoside triphosphate catabolic processGO:00091461220.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.024
circulatory system processGO:00030131830.024
purine ribonucleotide metabolic processGO:00091502270.024
regulation of cellular component organizationGO:00511283680.024
cellular response to lipidGO:00713962010.024
nucleoside catabolic processGO:00091641260.024
positive regulation of transcription dna templatedGO:00458931970.024
cell part morphogenesisGO:00329901230.024
cellular response to nitrogen compoundGO:19016992100.024
Mouse
regulation of phosphorylationGO:00423252480.024
growthGO:00400071650.024
protein phosphorylationGO:00064683450.024
nucleoside triphosphate metabolic processGO:00091411440.024
response to woundingGO:00096112540.023
head developmentGO:00603222470.023
cell cell signalingGO:00072673350.023
regulation of programmed cell deathGO:00430673410.023
Rat
response to peptide hormoneGO:00434342780.023
Mouse
positive regulation of response to stimulusGO:00485842850.023
cellular homeostasisGO:00197252520.023
purine nucleoside catabolic processGO:00061521240.023
cellular calcium ion homeostasisGO:00068741600.023
apoptotic processGO:00069153810.023
Rat
regulation of catalytic activityGO:00507903040.023
cellular response to stressGO:00335542690.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
regulation of cellular amino acid metabolic processGO:000652120.022
programmed cell deathGO:00125013920.022
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.022
hormone transportGO:00099141210.022
regulation of metal ion transportGO:00109591180.022
negative regulation of cellular protein metabolic processGO:00322691060.022
regulation of secretion by cellGO:19035302080.022
negative regulation of programmed cell deathGO:00430691830.022
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.021
insulin like growth factor receptor signaling pathwayGO:004800930.021
cellular amine metabolic processGO:0044106380.021
positive regulation of molecular functionGO:00440932300.021
regulation of system processGO:00440572080.021
regulation of lipid metabolic processGO:0019216680.021
Human
negative regulation of gene expressionGO:00106291990.021
regulation of hormone levelsGO:00108171870.021
organonitrogen compound catabolic processGO:19015651790.021
positive regulation of secretionGO:00510471400.021
regulation of transmembrane transportGO:00347621220.021
regulation of catabolic processGO:00098941130.021
Human
neurological system processGO:00508772190.020
single organism carbohydrate metabolic processGO:00447231180.020
organic acid transportGO:00158491160.020
positive regulation of cytosolic calcium ion concentrationGO:00072041220.020
cellular response to insulin stimulusGO:0032869810.020
Mouse
positive regulation of phosphorus metabolic processGO:00105622620.020
cellular response to organic cyclic compoundGO:00714072020.020
cofactor metabolic processGO:0051186950.020
axon developmentGO:0061564960.020
regulation of cell projection organizationGO:00313441750.020
response to monosaccharideGO:00342841590.019
macromolecule localizationGO:00330362520.019
cellular component morphogenesisGO:00329891550.019
response to ethanolGO:00454711620.019
protein localizationGO:00081041910.019
ribonucleoside catabolic processGO:00424541260.019
transcription from rna polymerase ii promoterGO:00063662520.019
multicellular organismal reproductive processGO:00486092330.019
Rat
ion homeostasisGO:00508012120.019
purine ribonucleoside triphosphate metabolic processGO:00092051400.019
regulation of transporter activityGO:0032409500.019
regulation of nucleotide catabolic processGO:0030811650.019
positive regulation of catalytic activityGO:00430851840.019
regulation of peptide hormone secretionGO:0090276800.019
gtp catabolic processGO:0006184710.019
lipid biosynthetic processGO:00086101280.019
enzyme linked receptor protein signaling pathwayGO:00071671160.019
cellular ion homeostasisGO:00068731840.019
response to carbohydrateGO:00097431830.019
response to oxygen levelsGO:00704822650.019
positive regulation of phosphorylationGO:00423271770.019
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.019
positive regulation of neuron differentiationGO:00456661260.019
organonitrogen compound biosynthetic processGO:19015661670.019
regulation of nervous system developmentGO:00519602640.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
response to glucoseGO:00097491360.019
tube developmentGO:0035295890.019
hormone secretionGO:00468791150.019
amine metabolic processGO:0009308380.018
divalent inorganic cation transportGO:00725111340.018
purine containing compound catabolic processGO:00725231380.018
regenerationGO:00310991630.018
positive regulation of protein modification processGO:00314011420.018
negative regulation of signalingGO:00230571570.018
calcium ion transportGO:00068161310.018
cell migrationGO:00164771970.018
dephosphorylationGO:0016311980.018
regulation of hormone secretionGO:00468831060.018
positive regulation of protein metabolic processGO:00512471780.018
regulation of cellular localizationGO:00603412630.018
positive regulation of hormone secretionGO:0046887650.018
regulation of hydrolase activityGO:00513361430.018
inflammatory responseGO:00069541500.018
cell morphogenesisGO:00009021420.018
positive regulation of nucleotide metabolic processGO:0045981910.018
positive regulation of intracellular signal transductionGO:19025331380.017
divalent inorganic cation homeostasisGO:00725071650.017
regulation of protein modification processGO:00313991940.017
response to oxidative stressGO:00069791860.017
regulation of anatomical structure morphogenesisGO:00226031410.017
Human
reproductive processGO:00224143720.017
Rat
cell morphogenesis involved in neuron differentiationGO:00486671060.017
positive regulation of protein phosphorylationGO:00019341350.017
negative regulation of transportGO:00510511360.017
positive regulation of neurogenesisGO:00507691650.017
protein oligomerizationGO:00512591910.017
gamete generationGO:00072761240.017
Rat
response to hypoxiaGO:00016662310.017
regulation of neuron projection developmentGO:00109751610.017
protein complex subunit organizationGO:00718223020.017
response to hexoseGO:00097461440.017
guanosine containing compound metabolic processGO:1901068740.017
lipid metabolic processGO:00066292830.016
protein complex biogenesisGO:00702712630.016
developmental process involved in reproductionGO:00030061590.016
Rat
regulation of cellular catabolic processGO:00313291010.016
cell growthGO:00160491040.016
cation homeostasisGO:00550801950.016
positive regulation of cellular amine metabolic processGO:003324030.016
multicellular organism reproductionGO:00325042330.016
Rat
organophosphate biosynthetic processGO:00904071430.016
nucleobase containing compound catabolic processGO:00346551520.016
gtp metabolic processGO:0046039720.016
cellular response to growth factor stimulusGO:00713631620.016
negative regulation of cellular biosynthetic processGO:00313271610.016
metal ion homeostasisGO:00550651860.016
response to alkaloidGO:00432791320.016
macromolecule catabolic processGO:0009057580.016
inorganic ion transmembrane transportGO:00986602290.016
cellular response to hormone stimulusGO:00328702470.016
Mouse
response to cytokineGO:00340972150.015
muscle structure developmentGO:0061061870.015
nucleoside metabolic processGO:00091161790.015
cell adhesionGO:00071551100.015
Human
multicellular organism growthGO:003526410.015
negative regulation of signal transductionGO:0009968830.015
regulation of neurogenesisGO:00507672470.015
positive regulation of peptide hormone secretionGO:0090277500.015
guanosine containing compound catabolic processGO:1901069710.015
regulation of protein localizationGO:0032880810.015
response to decreased oxygen levelsGO:00362932370.015
positive regulation of neuron projection developmentGO:0010976990.015
organic anion transportGO:00157111320.015
positive regulation of cellular amino acid metabolic processGO:004576410.014
heart developmentGO:0007507720.014
cellular response to cytokine stimulusGO:00713451270.014
regulation of homeostatic processGO:00328441010.014
regulation of cell growthGO:0001558850.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
response to molecule of bacterial originGO:00022371940.014
regulation of membrane potentialGO:00423911100.014
vesicle mediated transportGO:00161921810.014
amine transportGO:0015837570.014
alpha amino acid metabolic processGO:1901605710.014
regulation of nucleoside metabolic processGO:0009118660.014
localization of cellGO:00516742020.014
response to metal ionGO:00100382530.014
gland developmentGO:00487321550.014
positive regulation of cell differentiationGO:00455972170.014
regulation of anatomical structure sizeGO:00900661350.014
eye morphogenesisGO:004859240.014
positive regulation of catabolic processGO:0009896780.014
g protein coupled receptor signaling pathwayGO:00071862420.013
signal releaseGO:00230611450.013
response to other organismGO:00517072200.013
intracellular transportGO:00469071850.013
regulation of ion transmembrane transporter activityGO:0032412480.013
response to estradiolGO:00323551640.013
regulation of ion transmembrane transportGO:00347651210.013
muscle cell proliferationGO:0033002840.013
regulation of purine nucleotide catabolic processGO:0033121650.013
negative regulation of protein metabolic processGO:00512481140.013
kidney developmentGO:0001822670.013
peptide secretionGO:0002790860.013
blood circulationGO:00080151830.013
regulation of fat cell differentiationGO:004559830.013
monosaccharide metabolic processGO:0005996610.013
cellular protein localizationGO:00346131220.013
positive regulation of signal transductionGO:00099671750.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
positive regulation of programmed cell deathGO:00430681570.013
ribonucleoside monophosphate metabolic processGO:0009161880.013
peptidyl amino acid modificationGO:00181931260.013
regulation of blood circulationGO:19035221100.013
dna metabolic processGO:0006259960.013
ossificationGO:0001503700.013
negative regulation of biosynthetic processGO:00098901680.013
monovalent inorganic cation transportGO:00156721720.013
carbohydrate derivative biosynthetic processGO:19011371240.012
positive regulation of nucleoside metabolic processGO:0045979550.012
hepaticobiliary system developmentGO:0061008900.012
response to ketoneGO:19016541820.012
positive regulation of nervous system developmentGO:00519621780.012
regulation of peptide transportGO:0090087870.012
response to biotic stimulusGO:00096072260.012
cellular lipid metabolic processGO:00442552080.012
ras protein signal transductionGO:0007265290.012
nucleoside monophosphate metabolic processGO:0009123930.012
protein heterooligomerizationGO:0051291890.012
regulation of nucleotide metabolic processGO:00061401170.012
small gtpase mediated signal transductionGO:0007264360.012
organ morphogenesisGO:0009887750.012
nucleotide biosynthetic processGO:0009165980.012
positive regulation of cell projection organizationGO:00313461110.012
regulation of proteasomal protein catabolic processGO:006113640.012
renal system developmentGO:0072001670.012
negative regulation of transcription dna templatedGO:00458921160.012
peptide transportGO:0015833970.012
organ growthGO:0035265240.012
reactive oxygen species metabolic processGO:0072593370.012
neurotransmitter gated ion channel clusteringGO:007257830.011
cellular macromolecule localizationGO:00707271220.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
negative regulation of phosphate metabolic processGO:0045936800.011
negative regulation of cell proliferationGO:00082851190.011
respiratory system developmentGO:0060541450.011
negative regulation of phosphorus metabolic processGO:0010563800.011
cell type specific apoptotic processGO:00972851340.011
response to vitaminGO:00332731310.011
regulation of establishment of protein localizationGO:0070201690.011
sexual reproductionGO:00199531480.011
Rat
single organism behaviorGO:00447081300.011
carboxylic acid transportGO:00469421150.011
negative regulation of organ growthGO:004662130.011
sensory perception of painGO:0019233730.011
regulation of transmembrane transporter activityGO:0022898490.011
regulation of body fluid levelsGO:0050878900.011
positive regulation of hydrolase activityGO:0051345860.011
spermatogenesisGO:0007283990.011
response to low density lipoprotein particleGO:005509840.011
response to peptideGO:19016522920.011
Mouse
regulation of cell migrationGO:00303341280.011
palate developmentGO:006002120.011
regulation of cellular amine metabolic processGO:003323880.011
carbohydrate homeostasisGO:0033500750.011
Mouse
cellular response to external stimulusGO:00714961180.011
macromolecular complex subunit organizationGO:00439333390.011
negative regulation of heart growthGO:006111730.011
reproductive system developmentGO:00614581280.011
positive regulation of growthGO:0045927550.011
cellular response to alcoholGO:0097306870.011
regulation of developmental growthGO:0048638450.011
small molecule biosynthetic processGO:00442831240.011
cellular response to oxygen levelsGO:0071453600.011
single organism intracellular transportGO:19025821660.011
cation transmembrane transportGO:00986552630.010
regulation of locomotionGO:00400121480.010
organ regenerationGO:00311001010.010
negative regulation of cardiac muscle cell proliferationGO:006004420.010
response to testosteroneGO:0033574550.010
negative regulation of phosphorylationGO:0042326570.010
positive regulation of isotype switchingGO:004583010.010
steroid metabolic processGO:0008202730.010
mesenchymal cell proliferationGO:001046340.010
developmental growthGO:00485891000.010
positive regulation of cell developmentGO:00107201760.010
response to coldGO:0009409290.010
defense response to gram negative bacteriumGO:005082930.010
positive regulation of fat cell differentiationGO:004560020.010

Pde3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.047
disease of metabolismDOID:001466700.029
sensory system diseaseDOID:005015500.015
central nervous system diseaseDOID:33100.011
inherited metabolic disorderDOID:65500.011