Rattus norvegicus

0 known processes

Bik

BCL2-interacting killer (apoptosis-inducing)

(Aliases: Biklk,Blk)

Bik biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna biosynthetic processGO:00327743800.167
regulation of rna metabolic processGO:00512523910.092
regulation of cell proliferationGO:00421273590.090
regulation of transcription dna templatedGO:00063553740.083
positive regulation of nucleobase containing compound metabolic processGO:00459353190.080
positive regulation of multicellular organismal processGO:00512403870.079
nucleic acid templated transcriptionGO:00976593790.078
oxoacid metabolic processGO:00434362900.078
transcription dna templatedGO:00063513770.075
transcription from rna polymerase ii promoterGO:00063662520.069
regulation of nucleic acid templated transcriptionGO:19035063800.064
positive regulation of nitrogen compound metabolic processGO:00511733340.063
regulation of rna biosynthetic processGO:20011413810.063
cation homeostasisGO:00550801950.063
wnt signaling pathway planar cell polarity pathwayGO:006007120.063
positive regulation of cell proliferationGO:00082842490.060
rna metabolic processGO:00160704060.055
limb morphogenesisGO:003510840.054
organophosphate metabolic processGO:00196373700.053
positive regulation of biosynthetic processGO:00098913190.050
positive regulation of cellular biosynthetic processGO:00313282950.049
prostate gland epithelium morphogenesisGO:006074020.048
regulation of protein metabolic processGO:00512462890.047
chemical homeostasisGO:00488782920.047
divalent inorganic cation homeostasisGO:00725071650.046
regulation of apoptotic processGO:00429813350.045
calcium ion homeostasisGO:00550741620.045
positive regulation of signalingGO:00230562700.045
regulation of transcription from rna polymerase ii promoterGO:00063572340.044
gland developmentGO:00487321550.044
embryonic appendage morphogenesisGO:003511340.044
single organism reproductive processGO:00447022970.043
cellular response to stressGO:00335542690.042
negative regulation of macromolecule metabolic processGO:00106052600.041
rhythmic processGO:00485111560.040
regulation of cell differentiationGO:00455953200.040
carboxylic acid metabolic processGO:00197522890.039
neuron differentiationGO:00301823680.039
carbohydrate derivative metabolic processGO:19011353460.039
appendage morphogenesisGO:003510740.039
reproductive processGO:00224143720.038
cellular component movementGO:00069282480.038
positive regulation of developmental processGO:00510942830.037
regulation of epithelial cell proliferationGO:0050678490.037
multi organism reproductive processGO:00447032620.037
cellular divalent inorganic cation homeostasisGO:00725031620.037
cellular chemical homeostasisGO:00550822470.037
nucleobase containing small molecule metabolic processGO:00550863160.037
negative regulation of cell differentiationGO:0045596990.036
response to acid chemicalGO:00011012220.036
cellular response to lipidGO:00713962010.036
regulation of multicellular organismal developmentGO:20000263760.036
negative regulation of developmental processGO:00510931250.036
regulation of cellular amine metabolic processGO:003323880.036
anatomical structure morphogenesisGO:00096532980.036
cellular ketone metabolic processGO:0042180510.035
cellular homeostasisGO:00197252520.035
organic acid metabolic processGO:00060822920.035
agingGO:00075682410.034
positive regulation of protein modification processGO:00314011420.034
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.034
nucleoside phosphate metabolic processGO:00067532830.034
cellular component biogenesisGO:00440853680.034
cellular cation homeostasisGO:00300031800.033
positive regulation of macromolecule biosynthetic processGO:00105572470.033
cellular amino acid metabolic processGO:00065201070.033
negative regulation of cell deathGO:00605482290.033
positive regulation of molecular functionGO:00440932300.033
cellular amine metabolic processGO:0044106380.032
localization of cellGO:00516742020.032
positive regulation of apoptotic processGO:00430651540.032
amine metabolic processGO:0009308380.032
metal ion homeostasisGO:00550651860.031
cellular ion homeostasisGO:00068731840.031
regulation of protein phosphorylationGO:00019321830.031
organ morphogenesisGO:0009887750.030
response to ketoneGO:19016541820.030
macromolecular complex assemblyGO:00650032730.030
regulation of cellular amino acid metabolic processGO:000652120.030
regulation of phosphorus metabolic processGO:00511743490.030
regulation of cellular component organizationGO:00511283680.030
tube developmentGO:0035295890.030
cytosolic calcium ion homeostasisGO:00514801400.030
lipid metabolic processGO:00066292830.030
negative regulation of multicellular organismal processGO:00512412030.030
central nervous system developmentGO:00074173110.029
cell migrationGO:00164771970.029
positive regulation of phosphorus metabolic processGO:00105622620.029
regulation of cellular ketone metabolic processGO:0010565270.028
homeostatic processGO:00425923310.028
positive regulation of protein metabolic processGO:00512471780.028
protein phosphorylationGO:00064683450.028
regulation of protein modification processGO:00313991940.027
reproductive structure developmentGO:00486081280.027
positive regulation of transcription dna templatedGO:00458931970.027
regulation of phosphate metabolic processGO:00192203490.026
anatomical structure formation involved in morphogenesisGO:0048646830.026
positive regulation of response to stimulusGO:00485842850.026
anterior posterior pattern specificationGO:000995210.026
ion homeostasisGO:00508012120.026
cellular metal ion homeostasisGO:00068751720.026
intracellular signal transductionGO:00355563140.026
gonad developmentGO:00084061040.026
negative regulation of nucleobase containing compound metabolic processGO:00459341530.025
response to ethanolGO:00454711620.025
positive regulation of cell deathGO:00109421840.025
metal ion transportGO:00300012890.025
regulation of anatomical structure morphogenesisGO:00226031410.025
positive regulation of cellular protein metabolic processGO:00322701670.025
regulation of cellular protein metabolic processGO:00322682670.025
embryonic limb morphogenesisGO:003032640.025
response to peptideGO:19016522920.025
response to inorganic substanceGO:00100353770.025
positive regulation of cell differentiationGO:00455972170.024
regulation of establishment of planar polarityGO:009017520.024
response to lipopolysaccharideGO:00324961910.024
positive regulation of phosphorylationGO:00423271770.024
regulation of bmp signaling pathwayGO:003051020.024
cellular calcium ion homeostasisGO:00068741600.024
cell motilityGO:00488702020.024
positive regulation of phosphate metabolic processGO:00459372620.024
multicellular organismal reproductive processGO:00486092330.024
cellular response to endogenous stimulusGO:00714953770.024
positive regulation of cell developmentGO:00107201760.024
intracellular transportGO:00469071850.023
single organism biosynthetic processGO:00447113420.023
programmed cell deathGO:00125013920.023
organelle organizationGO:00069962660.023
eye morphogenesisGO:004859240.023
positive regulation of rna biosynthetic processGO:19026801970.023
regulation of nervous system developmentGO:00519602640.023
negative regulation of metabolic processGO:00098923310.023
negative regulation of programmed cell deathGO:00430691830.023
multicellular organism reproductionGO:00325042330.023
negative regulation of cell developmentGO:0010721820.022
protein complex assemblyGO:00064612630.022
regulation of cell developmentGO:00602842630.022
protein complex subunit organizationGO:00718223020.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
calcium ion transportGO:00068161310.022
regulation of programmed cell deathGO:00430673410.022
ribose phosphate metabolic processGO:00196932350.022
cell projection organizationGO:00300303020.022
reproductive system developmentGO:00614581280.022
female sex differentiationGO:0046660590.021
regulation of synaptic transmissionGO:00508041410.021
regulation of neurogenesisGO:00507672470.021
regulation of phosphorylationGO:00423252480.021
positive regulation of protein phosphorylationGO:00019341350.021
prostate gland morphogenesisGO:006051220.021
negative regulation of rna metabolic processGO:00512531230.021
epithelium developmentGO:0060429960.021
macromolecular complex subunit organizationGO:00439333390.021
negative regulation of biosynthetic processGO:00098901680.021
purine nucleotide metabolic processGO:00061632290.021
regulation of ion transportGO:00432692450.021
positive regulation of cellular amine metabolic processGO:003324030.020
response to extracellular stimulusGO:00099913800.020
epithelial cell proliferationGO:0050673540.020
positive regulation of rna metabolic processGO:00512542030.020
circadian rhythmGO:0007623880.020
digestive system developmentGO:0055123410.020
single organism organelle organizationGO:19025891800.020
axis specificationGO:000979840.020
positive regulation of cellular component movementGO:00512721020.020
response to estrogenGO:00436272320.020
heart morphogenesisGO:000300730.020
locomotionGO:00400112370.020
cation transportGO:00068123820.020
response to estradiolGO:00323551640.020
carbohydrate derivative biosynthetic processGO:19011371240.020
positive regulation of cellular amino acid metabolic processGO:004576410.019
nucleotide metabolic processGO:00091172790.019
establishment of tissue polarityGO:000716420.019
cellular catabolic processGO:00442482950.019
multi multicellular organism processGO:00447061380.019
negative regulation of transportGO:00510511360.019
negative regulation of gene expressionGO:00106291990.019
immune system processGO:00023762040.019
regenerationGO:00310991630.019
cellular component morphogenesisGO:00329891550.018
cellular response to oxygen containing compoundGO:19017013860.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
regulation of hydrolase activityGO:00513361430.018
response to oxygen levelsGO:00704822650.018
negative regulation of nervous system developmentGO:0051961790.018
neurological system processGO:00508772190.018
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
response to woundingGO:00096112540.018
divalent inorganic cation transportGO:00725111340.017
negative regulation of transcription dna templatedGO:00458921160.017
reproductionGO:00000032450.017
female pregnancyGO:00075651220.017
positive regulation of cell migrationGO:0030335960.017
cell cell signalingGO:00072673350.017
cellular component assemblyGO:00226073600.017
non canonical wnt signaling pathwayGO:003556730.017
vasculature developmentGO:0001944700.017
cardiovascular system developmentGO:00723581340.017
inorganic ion transmembrane transportGO:00986602290.017
brain developmentGO:00074202470.017
response to retinoic acidGO:0032526630.017
positive regulation of neurogenesisGO:00507691650.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
regulation of cell migrationGO:00303341280.016
regulation of cell motilityGO:20001451310.016
single organism intracellular transportGO:19025821660.016
ribonucleoside metabolic processGO:00091191740.016
camera type eye developmentGO:0043010480.016
positive regulation of catalytic activityGO:00430851840.016
growthGO:00400071650.016
regulation of signal transductionGO:00099663180.016
catabolic processGO:00090563510.016
ribonucleotide metabolic processGO:00092592310.016
apoptotic processGO:00069153810.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
b cell differentiationGO:003018320.016
development of primary female sexual characteristicsGO:0046545560.016
cellular protein localizationGO:00346131220.016
cellular macromolecule localizationGO:00707271220.016
development of primary sexual characteristicsGO:00451371070.016
protein localizationGO:00081041910.016
developmental process involved in reproductionGO:00030061590.016
cell cycleGO:00070491010.016
regulation of growthGO:00400081050.016
organophosphate biosynthetic processGO:00904071430.015
response to decreased oxygen levelsGO:00362932370.015
metestrusGO:006021010.015
blood vessel developmentGO:0001568690.015
purine ribonucleotide metabolic processGO:00091502270.015
regulation of organelle organizationGO:0033043800.015
cell morphogenesisGO:00009021420.015
sensory organ developmentGO:0007423740.015
embryonic pattern specificationGO:000988010.015
neuron projection developmentGO:00311752730.015
positive regulation of nervous system developmentGO:00519621780.015
blood circulationGO:00080151830.015
wound healingGO:00420601220.015
bmp signaling pathwayGO:003050940.015
neuron developmentGO:00486662860.015
cellular response to lipopolysaccharideGO:0071222550.015
cell morphogenesis involved in differentiationGO:00009041190.015
positive regulation of locomotionGO:00400171020.015
epithelial cell differentiationGO:0030855710.015
response to molecule of bacterial originGO:00022371940.015
ion transmembrane transportGO:00342203650.015
lung developmentGO:0030324430.015
negative regulation of cell proliferationGO:00082851190.015
sex differentiationGO:00075481130.015
cellular response to fluid shear stressGO:007149840.015
negative regulation of neurogenesisGO:0050768780.015
synaptic transmissionGO:00072682350.015
cellular response to hormone stimulusGO:00328702470.015
negative regulation of cellular metabolic processGO:00313242810.015
response to peptide hormoneGO:00434342780.015
digestive tract developmentGO:0048565390.015
response to vitaminGO:00332731310.014
circulatory system developmentGO:00723591340.014
ras protein signal transductionGO:0007265290.014
ensheathment of neuronsGO:0007272400.014
positive regulation of epithelial cell proliferationGO:0050679320.014
purine containing compound metabolic processGO:00725212530.014
cellular response to abiotic stimulusGO:0071214850.014
dna metabolic processGO:0006259960.014
positive regulation of gene expressionGO:00106282440.014
regulation of neuron differentiationGO:00456642080.014
secretionGO:00469033070.014
negative regulation of apoptotic processGO:00430661810.014
inner ear receptor cell differentiationGO:006011320.014
gliogenesisGO:0042063930.014
regulation of protein kinase activityGO:00458591050.014
response to indole 3 methanolGO:007168020.014
head developmentGO:00603222470.013
sexual reproductionGO:00199531480.013
female gonad developmentGO:0008585530.013
response to glucoseGO:00097491360.013
regulation of molecular functionGO:00650093980.013
regulation of cellular localizationGO:00603412630.013
multicellular organismal signalingGO:0035637440.013
reactive oxygen species metabolic processGO:0072593370.013
cation transmembrane transportGO:00986552630.013
response to oxidative stressGO:00069791860.013
regulation of catalytic activityGO:00507903040.013
positive regulation of signal transductionGO:00099671750.013
positive regulation of programmed cell deathGO:00430681570.013
cell activationGO:0001775970.013
establishment of planar polarityGO:000173610.013
organic cyclic compound catabolic processGO:19013611750.013
multicellular organism growthGO:003526410.013
mesoderm developmentGO:000749820.013
neural crest cell differentiationGO:001403320.013
negative regulation of cell communicationGO:00106481580.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
small molecule biosynthetic processGO:00442831240.013
cellular response to biotic stimulusGO:0071216590.013
morphogenesis of a polarized epitheliumGO:000173810.013
embryonic hindlimb morphogenesisGO:003511620.013
regulation of immune system processGO:00026821230.013
regulation of cell cycleGO:0051726730.013
nucleoside metabolic processGO:00091161790.013
potassium ion transportGO:0006813970.013
regulation of homeostatic processGO:00328441010.012
cytoplasmic transportGO:00164821150.012
nucleoside phosphate biosynthetic processGO:19012931020.012
transmission of nerve impulseGO:0019226420.012
establishment of protein localizationGO:00451841410.012
neuron fate commitmentGO:004866340.012
response to cytokineGO:00340972150.012
cellular response to growth factor stimulusGO:00713631620.012
regulation of vasculature developmentGO:1901342440.012
response to metal ionGO:00100382530.012
monovalent inorganic cation transportGO:00156721720.012
small gtpase mediated signal transductionGO:0007264360.012
gastrulationGO:000736920.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
response to reactive oxygen speciesGO:00003021200.012
regulation of transferase activityGO:00513381230.012
response to glucocorticoidGO:00513842230.012
negative regulation of neuron differentiationGO:0045665620.012
response to growth factorGO:00708481890.012
response to insulinGO:00328681330.012
mechanoreceptor differentiationGO:004249020.012
response to nutrient levelsGO:00316673700.012
spermatogenesisGO:0007283990.012
organonitrogen compound biosynthetic processGO:19015661670.012
purine nucleoside catabolic processGO:00061521240.012
morphogenesis of embryonic epitheliumGO:001633130.011
neural crest cell developmentGO:001403220.011
maintenance of locationGO:0051235170.011
cellular nitrogen compound catabolic processGO:00442701630.011
lipid storageGO:001991510.011
purine nucleoside metabolic processGO:00422781690.011
vasculogenesisGO:000157030.011
response to testosteroneGO:0033574550.011
positive regulation of intracellular signal transductionGO:19025331380.011
sequestering of metal ionGO:005123890.011
response to transition metal nanoparticleGO:19902671220.011
carbohydrate derivative catabolic processGO:19011361470.011
response to hypoxiaGO:00016662310.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
positive regulation of hepatocyte differentiationGO:007036820.011
regulation of membrane potentialGO:00423911100.011
regulation of cell growthGO:0001558850.011
sodium ion transportGO:0006814820.011
inner ear morphogenesisGO:004247210.011
male sex differentiationGO:0046661640.011
cellular response to external stimulusGO:00714961180.011
negative regulation of cellular protein metabolic processGO:00322691060.011
protein complex biogenesisGO:00702712630.011
cell growthGO:00160491040.011
camera type eye morphogenesisGO:004859320.011
cell differentiation involved in kidney developmentGO:006100540.011
regulation of nucleotide metabolic processGO:00061401170.011
regulation of fat cell differentiationGO:004559830.011
tissue developmentGO:00098882520.011
purine ribonucleoside catabolic processGO:00461301240.011
response to external biotic stimulusGO:00432072210.011
proteolysisGO:00065081750.011
regulation of cell morphogenesisGO:0022604770.011
negative regulation of homeostatic processGO:0032845470.011
regulation of tube sizeGO:0035150890.010
negative regulation of molecular functionGO:00440921330.010
hepaticobiliary system developmentGO:0061008900.010
negative regulation of cellular component organizationGO:0051129830.010
peptidyl amino acid modificationGO:00181931260.010
ovulation cycle processGO:0022602500.010
negative regulation of signalingGO:00230571570.010
palate developmentGO:006002120.010
ribonucleoside catabolic processGO:00424541260.010
organic substance catabolic processGO:19015753160.010
regulation of canonical wnt signaling pathwayGO:006082840.010
regulation of developmental growthGO:0048638450.010
negative regulation of rna biosynthetic processGO:19026791180.010
cellular response to alcoholGO:0097306870.010
tube formationGO:003514830.010
negative regulation of cellular biosynthetic processGO:00313271610.010
eye developmentGO:0001654500.010
regulation of system processGO:00440572080.010

Bik disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.023
disease of anatomical entityDOID:700.023
sensory system diseaseDOID:005015500.018
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.011
gastrointestinal system cancerDOID:311900.010
vascular diseaseDOID:17800.010
cardiovascular system diseaseDOID:128700.010