Rattus norvegicus

17 known processes

Wfs1

Wolfram syndrome 1 homolog (human)

Wfs1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component biogenesisGO:00440853680.083
regulation of cell proliferationGO:00421273590.082
regulation of nucleic acid templated transcriptionGO:19035063800.080
cellular component assemblyGO:00226073600.070
cell motilityGO:00488702020.069
single organism biosynthetic processGO:00447113420.066
nucleic acid templated transcriptionGO:00976593790.065
rna metabolic processGO:00160704060.064
carboxylic acid metabolic processGO:00197522890.064
catabolic processGO:00090563510.063
organic acid metabolic processGO:00060822920.063
locomotionGO:00400112370.061
cell cell signalingGO:00072673350.061
organic substance catabolic processGO:19015753160.059
neuron differentiationGO:00301823680.056
protein complex biogenesisGO:00702712630.055
regulation of rna metabolic processGO:00512523910.053
regulation of locomotionGO:00400121480.050
central nervous system developmentGO:00074173110.050
nucleoside phosphate metabolic processGO:00067532830.049
cell projection organizationGO:00300303020.049
oxoacid metabolic processGO:00434362900.049
organonitrogen compound catabolic processGO:19015651790.049
rna biosynthetic processGO:00327743800.048
cellular response to oxygen containing compoundGO:19017013860.048
regulation of rna biosynthetic processGO:20011413810.047
carbohydrate derivative metabolic processGO:19011353460.047
response to metal ionGO:00100382530.044
transcription dna templatedGO:00063513770.044
macromolecular complex assemblyGO:00650032730.044
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.043
protein complex assemblyGO:00064612630.041
head developmentGO:00603222470.040
nucleoside phosphate catabolic processGO:19012921400.040
secretionGO:00469033070.039
neuron projection developmentGO:00311752730.038
regulation of signal transductionGO:00099663180.038
localization of cellGO:00516742020.037
positive regulation of response to stimulusGO:00485842850.036
response to oxygen levelsGO:00704822650.036
anion transportGO:00068201780.035
ion transmembrane transportGO:00342203650.035
regulation of phosphate metabolic processGO:00192203490.035
nucleoside metabolic processGO:00091161790.035
regulation of apoptotic processGO:00429813350.034
carbohydrate derivative catabolic processGO:19011361470.034
nucleobase containing small molecule metabolic processGO:00550863160.034
positive regulation of nitrogen compound metabolic processGO:00511733340.034
positive regulation of phosphorus metabolic processGO:00105622620.032
neuron projection morphogenesisGO:00488121220.032
single organism catabolic processGO:00447122830.032
cellular component movementGO:00069282480.031
regulation of transcription dna templatedGO:00063553740.031
regulation of catalytic activityGO:00507903040.031
apoptotic processGO:00069153810.031
ribonucleoside metabolic processGO:00091191740.031
ribose phosphate metabolic processGO:00196932350.031
blood circulationGO:00080151830.030
regulation of cellular ketone metabolic processGO:0010565270.030
lipid metabolic processGO:00066292830.030
cellular ketone metabolic processGO:0042180510.030
purine ribonucleotide catabolic processGO:00091541360.030
purine containing compound catabolic processGO:00725231380.030
regulation of cellular amino acid metabolic processGO:000652120.029
synaptic transmissionGO:00072682350.029
response to nutrient levelsGO:00316673700.029
negative regulation of rna biosynthetic processGO:19026791180.029
macromolecular complex subunit organizationGO:00439333390.029
purine ribonucleotide metabolic processGO:00091502270.028
organophosphate metabolic processGO:00196373700.028
organic cyclic compound catabolic processGO:19013611750.028
negative regulation of signalingGO:00230571570.028
aromatic compound catabolic processGO:00194391680.028
response to inorganic substanceGO:00100353770.028
response to decreased oxygen levelsGO:00362932370.028
regulation of cellular component organizationGO:00511283680.027
positive regulation of phosphate metabolic processGO:00459372620.027
cell migrationGO:00164771970.027
regulation of cell developmentGO:00602842630.027
transcription from rna polymerase ii promoterGO:00063662520.027
tissue developmentGO:00098882520.027
cellular catabolic processGO:00442482950.027
purine nucleotide catabolic processGO:00061951360.027
anterior posterior pattern specificationGO:000995210.027
nucleobase containing compound catabolic processGO:00346551520.027
response to peptide hormoneGO:00434342780.027
transmembrane transportGO:00550854120.026
brain developmentGO:00074202470.026
protein oligomerizationGO:00512591910.026
circulatory system processGO:00030131830.026
regulation of hormone levelsGO:00108171870.026
response to growth factorGO:00708481890.026
signal releaseGO:00230611450.026
negative regulation of cell communicationGO:00106481580.026
cellular amino acid metabolic processGO:00065201070.025
monocarboxylic acid metabolic processGO:00327871520.025
purine nucleotide metabolic processGO:00061632290.025
homeostatic processGO:00425923310.025
purine nucleoside triphosphate metabolic processGO:00091441410.025
regulation of nervous system developmentGO:00519602640.025
regulation of catabolic processGO:00098941130.025
nucleotide metabolic processGO:00091172790.025
chemical homeostasisGO:00488782920.025
positive regulation of biosynthetic processGO:00098913190.025
regulation of phosphorus metabolic processGO:00511743490.025
protein complex subunit organizationGO:00718223020.025
inorganic cation transmembrane transportGO:00986622020.025
negative regulation of metabolic processGO:00098923310.024
purine ribonucleoside metabolic processGO:00461281680.024
purine nucleoside metabolic processGO:00422781690.024
positive regulation of signalingGO:00230562700.024
negative regulation of rna metabolic processGO:00512531230.024
positive regulation of cellular biosynthetic processGO:00313282950.024
response to extracellular stimulusGO:00099913800.024
regulation of anatomical structure sizeGO:00900661350.024
regulation of secretionGO:00510462240.023
response to estrogenGO:00436272320.023
nucleoside triphosphate metabolic processGO:00091411440.023
secretion by cellGO:00329402480.023
regulation of cellular catabolic processGO:00313291010.023
amine metabolic processGO:0009308380.022
nucleotide catabolic processGO:00091661390.022
glycosyl compound metabolic processGO:19016571820.022
ribonucleotide metabolic processGO:00092592310.022
positive regulation of developmental processGO:00510942830.022
positive regulation of neurogenesisGO:00507691650.022
purine containing compound metabolic processGO:00725212530.022
regulation of cellular localizationGO:00603412630.022
reproductive processGO:00224143720.022
glycosyl compound catabolic processGO:19016581260.022
ribonucleoside catabolic processGO:00424541260.021
regulation of cell motilityGO:20001451310.021
positive regulation of multicellular organismal processGO:00512403870.021
positive regulation of molecular functionGO:00440932300.021
negative regulation of biosynthetic processGO:00098901680.021
regulation of secretion by cellGO:19035302080.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
negative regulation of gene expressionGO:00106291990.021
regulation of molecular functionGO:00650093980.021
regulation of protein metabolic processGO:00512462890.021
negative regulation of cell proliferationGO:00082851190.021
response to nutrientGO:00075842480.021
positive regulation of cell differentiationGO:00455972170.021
negative regulation of nucleic acid templated transcriptionGO:19035071170.021
single organism cellular localizationGO:19025801020.020
cellular lipid metabolic processGO:00442552080.020
gland developmentGO:00487321550.020
regulation of ion transportGO:00432692450.020
response to acid chemicalGO:00011012220.020
multicellular organism growthGO:003526410.020
regulation of phosphorylationGO:00423252480.020
negative regulation of transcription dna templatedGO:00458921160.020
organophosphate catabolic processGO:00464341480.020
regulation of neurogenesisGO:00507672470.020
forebrain developmentGO:0030900980.020
cellular amine metabolic processGO:0044106380.020
cellular response to nitrogen compoundGO:19016992100.020
neuron developmentGO:00486662860.020
programmed cell deathGO:00125013920.020
organic anion transportGO:00157111320.020
negative regulation of macromolecule metabolic processGO:00106052600.020
response to peptideGO:19016522920.020
regulation of programmed cell deathGO:00430673410.020
nucleoside triphosphate catabolic processGO:00091431230.020
purine ribonucleoside triphosphate metabolic processGO:00092051400.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
regulation of neuron differentiationGO:00456642080.020
regulation of cell differentiationGO:00455953200.020
regenerationGO:00310991630.019
negative regulation of nitrogen compound metabolic processGO:00511721610.019
positive regulation of catabolic processGO:0009896780.019
positive regulation of protein metabolic processGO:00512471780.019
negative regulation of cellular biosynthetic processGO:00313271610.019
macromolecule localizationGO:00330362520.019
oxidation reduction processGO:00551143040.019
inorganic ion transmembrane transportGO:00986602290.019
cell morphogenesisGO:00009021420.019
agingGO:00075682410.019
positive regulation of cell developmentGO:00107201760.019
organic acid transportGO:00158491160.019
regulation of cellular amine metabolic processGO:003323880.019
small gtpase mediated signal transductionGO:0007264360.019
cation transportGO:00068123820.019
protein transportGO:00150311320.019
cell projection morphogenesisGO:00488581230.019
positive regulation of cell proliferationGO:00082842490.019
positive regulation of protein phosphorylationGO:00019341350.018
anion transmembrane transportGO:0098656770.018
ribonucleotide catabolic processGO:00092611360.018
regulation of intracellular signal transductionGO:19025312180.018
response to monosaccharideGO:00342841590.018
regulation of nucleotide metabolic processGO:00061401170.018
nitrogen compound transportGO:00717052290.018
positive regulation of cell communicationGO:00106472710.018
guanosine containing compound metabolic processGO:1901068740.018
heterocycle catabolic processGO:00467001670.018
single organism organelle organizationGO:19025891800.018
multicellular organism reproductionGO:00325042330.018
intracellular transportGO:00469071850.017
response to external biotic stimulusGO:00432072210.017
developmental process involved in reproductionGO:00030061590.017
heart morphogenesisGO:000300730.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
multi organism reproductive processGO:00447032620.017
intracellular signal transductionGO:00355563140.017
rhythmic processGO:00485111560.017
single organism reproductive processGO:00447022970.017
response to toxic substanceGO:00096361330.017
regulation of protein modification processGO:00313991940.017
regulation of multicellular organismal developmentGO:20000263760.017
cellular component morphogenesisGO:00329891550.017
regulation of cell migrationGO:00303341280.017
cardiac chamber developmentGO:000320510.017
cellular response to hormone stimulusGO:00328702470.017
axon developmentGO:0061564960.017
response to glucoseGO:00097491360.017
regulation of protein phosphorylationGO:00019321830.017
regulation of cellular protein metabolic processGO:00322682670.016
regulation of cellular component movementGO:00512701500.016
monovalent inorganic cation transportGO:00156721720.016
regulation of purine nucleotide catabolic processGO:0033121650.016
positive regulation of gene expressionGO:00106282440.016
response to ketoneGO:19016541820.016
positive regulation of nervous system developmentGO:00519621780.016
cellular response to endogenous stimulusGO:00714953770.016
peptide secretionGO:0002790860.016
response to carbohydrateGO:00097431830.016
neurological system processGO:00508772190.016
regulation of neuron projection developmentGO:00109751610.016
positive regulation of cellular amine metabolic processGO:003324030.016
positive regulation of signal transductionGO:00099671750.016
negative regulation of transportGO:00510511360.016
response to purine containing compoundGO:00140741260.016
ras protein signal transductionGO:0007265290.016
positive regulation of transportGO:00510502450.016
positive regulation of gtpase activityGO:0043547470.016
regulation of hydrolase activityGO:00513361430.016
positive regulation of neuron differentiationGO:00456661260.015
negative regulation of cellular metabolic processGO:00313242810.015
axis specificationGO:000979840.015
cation transmembrane transportGO:00986552630.015
response to estradiolGO:00323551640.015
lipid biosynthetic processGO:00086101280.015
positive regulation of cell deathGO:00109421840.015
positive regulation of locomotionGO:00400171020.015
response to hypoxiaGO:00016662310.015
cellular response to growth factor stimulusGO:00713631620.015
cellular response to organic cyclic compoundGO:00714072020.015
cellular nitrogen compound catabolic processGO:00442701630.015
response to woundingGO:00096112540.015
cellular response to lipidGO:00713962010.015
cellular homeostasisGO:00197252520.015
multicellular organismal reproductive processGO:00486092330.015
action potentialGO:0001508540.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
lipid modificationGO:0030258520.015
response to mechanical stimulusGO:00096121340.015
response to campGO:0051591910.015
regulation of body fluid levelsGO:0050878900.014
regulation of purine nucleotide metabolic processGO:19005421150.014
single organism behaviorGO:00447081300.014
response to organophosphorusGO:00466831020.014
defense responseGO:00069521940.014
positive regulation of phosphorylationGO:00423271770.014
regulation of gtp catabolic processGO:0033124580.014
cellular response to external stimulusGO:00714961180.014
regulation of peptide hormone secretionGO:0090276800.014
regulation of peptide transportGO:0090087870.014
regulation of synaptic transmissionGO:00508041410.014
carbohydrate metabolic processGO:00059751300.014
reproductionGO:00000032450.014
nucleoside catabolic processGO:00091641260.014
regulation of nucleoside metabolic processGO:0009118660.014
anatomical structure morphogenesisGO:00096532980.014
response to retinoic acidGO:0032526630.014
response to biotic stimulusGO:00096072260.014
purine nucleoside catabolic processGO:00061521240.013
glycogen metabolic processGO:0005977230.013
carboxylic acid transportGO:00469421150.013
positive regulation of rna metabolic processGO:00512542030.013
response to hexoseGO:00097461440.013
appendage morphogenesisGO:003510740.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
positive regulation of transcription dna templatedGO:00458931970.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
negative regulation of response to stimulusGO:00485851550.013
cellular protein localizationGO:00346131220.013
telencephalon developmentGO:0021537620.013
insulin like growth factor receptor signaling pathwayGO:004800930.013
response to interleukin 1GO:0070555550.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
positive regulation of catalytic activityGO:00430851840.013
peptidyl amino acid modificationGO:00181931260.013
regulation of peptide secretionGO:0002791820.013
regulation of system processGO:00440572080.013
positive regulation of cellular component organizationGO:00511302000.013
peptide transportGO:0015833970.013
sexual reproductionGO:00199531480.013
regulation of canonical wnt signaling pathwayGO:006082840.013
response to glucocorticoidGO:00513842230.013
embryonic pattern specificationGO:000988010.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
positive regulation of macromolecule biosynthetic processGO:00105572470.012
ovulation cycleGO:0042698670.012
response to bacteriumGO:00096172000.012
positive regulation of programmed cell deathGO:00430681570.012
regulation of blood vessel sizeGO:0050880890.012
cell cycleGO:00070491010.012
sodium ion transportGO:0006814820.012
reactive nitrogen species metabolic processGO:200105710.012
gliogenesisGO:0042063930.012
positive regulation of cellular catabolic processGO:0031331710.012
positive regulation of apoptotic processGO:00430651540.012
immune system processGO:00023762040.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
wound healingGO:00420601220.012
cellular macromolecule localizationGO:00707271220.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
heart contractionGO:0060047570.012
response to corticosteroidGO:00319602350.012
cell growthGO:00160491040.012
regulation of cell projection organizationGO:00313441750.012
protein phosphorylationGO:00064683450.012
monocarboxylic acid transportGO:0015718520.012
regulation of transferase activityGO:00513381230.012
single organism intracellular transportGO:19025821660.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of cellular component movementGO:00512721020.011
response to lipopolysaccharideGO:00324961910.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
positive regulation of nucleotide metabolic processGO:0045981910.011
cell morphogenesis involved in differentiationGO:00009041190.011
negative regulation of multicellular organismal processGO:00512412030.011
purine nucleoside monophosphate metabolic processGO:0009126840.011
negative regulation of protein import into nucleus translocationGO:003315910.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
behaviorGO:00076102050.011
actin filament based processGO:0030029860.011
neuromuscular synaptic transmissionGO:000727420.011
guanosine containing compound catabolic processGO:1901069710.011
cytoplasmic transportGO:00164821150.011
cell part morphogenesisGO:00329901230.011
heart processGO:0003015570.011
single organism carbohydrate metabolic processGO:00447231180.011
regulation of tube sizeGO:0035150890.011
response to vitaminGO:00332731310.011
positive regulation of secretionGO:00510471400.011
regulation of transmembrane transportGO:00347621220.011
response to other organismGO:00517072200.011
regulation of neurotransmitter levelsGO:0001505420.011
regulation of nucleotide catabolic processGO:0030811650.011
hormone transportGO:00099141210.011
response to starvationGO:0042594590.011
positive regulation of cell motilityGO:2000147970.011
regulation of hormone secretionGO:00468831060.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
negative regulation of secretionGO:0051048820.011
insulin secretionGO:0030073690.011
muscle structure developmentGO:0061061870.011
response to ethanolGO:00454711620.011
regulation of behaviorGO:0050795610.010
defense response to gram negative bacteriumGO:005082930.010
regulation of membrane potentialGO:00423911100.010
muscle cell proliferationGO:0033002840.010
cellular response to cytokine stimulusGO:00713451270.010
pallium developmentGO:0021543420.010
camera type eye developmentGO:0043010480.010
motor neuron axon guidanceGO:000804510.010
response to transition metal nanoparticleGO:19902671220.010
response to cytokineGO:00340972150.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
embryo developmentGO:0009790490.010
positive regulation of mapk cascadeGO:0043410920.010
negative regulation of signal transductionGO:0009968830.010
peptide hormone secretionGO:0030072840.010
response to reactive oxygen speciesGO:00003021200.010
rho protein signal transductionGO:0007266110.010

Wfs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
disease of metabolismDOID:001466700.019
cardiovascular system diseaseDOID:128700.017
inherited metabolic disorderDOID:65500.016
musculoskeletal system diseaseDOID:1700.015
central nervous system diseaseDOID:33100.011