Rattus norvegicus

21 known processes

Rock1

Rho-associated coiled-coil containing protein kinase 1

(Aliases: P160Rock)

Rock1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
homeostatic processGO:00425923310.136
reproductive processGO:00224143720.116
Fly
cellular response to oxygen containing compoundGO:19017013860.115
organelle organizationGO:00069962660.091
organ morphogenesisGO:0009887750.089
Fly
cell type specific apoptotic processGO:00972851340.085
Mouse
rna metabolic processGO:00160704060.080
regulation of cell proliferationGO:00421273590.079
regulation of secretion by cellGO:19035302080.078
cellular component assemblyGO:00226073600.078
Mouse Fly
epithelium developmentGO:0060429960.078
Human Mouse Fly
transcription dna templatedGO:00063513770.078
protein complex subunit organizationGO:00718223020.077
Fly
response to estradiolGO:00323551640.075
protein complex biogenesisGO:00702712630.074
regulation of rna metabolic processGO:00512523910.072
multi organism reproductive processGO:00447032620.071
Fly
cellular component movementGO:00069282480.070
Human Mouse Rat Fly
response to inorganic substanceGO:00100353770.069
regulation of rna biosynthetic processGO:20011413810.068
positive regulation of nitrogen compound metabolic processGO:00511733340.068
transcription from rna polymerase ii promoterGO:00063662520.067
positive regulation of nucleobase containing compound metabolic processGO:00459353190.066
positive regulation of biosynthetic processGO:00098913190.066
reproductionGO:00000032450.063
Fly
response to estrogenGO:00436272320.062
nitrogen compound transportGO:00717052290.061
regulation of cell developmentGO:00602842630.061
Fly
cellular response to peptideGO:19016531330.061
locomotionGO:00400112370.057
Human Mouse Rat
intracellular signal transductionGO:00355563140.056
cell migrationGO:00164771970.055
Human Mouse Rat
single organism reproductive processGO:00447022970.055
Fly
cellular homeostasisGO:00197252520.055
anatomical structure morphogenesisGO:00096532980.054
Human Mouse Fly
carbohydrate derivative biosynthetic processGO:19011371240.054
reproductive system developmentGO:00614581280.054
regulation of transcription from rna polymerase ii promoterGO:00063572340.054
divalent inorganic cation transportGO:00725111340.053
macromolecular complex assemblyGO:00650032730.052
negative regulation of macromolecule metabolic processGO:00106052600.051
regulation of cellular component organizationGO:00511283680.051
Mouse Fly
rna biosynthetic processGO:00327743800.051
regulation of hormone levelsGO:00108171870.050
neuron differentiationGO:00301823680.050
Fly
multicellular organism reproductionGO:00325042330.050
Fly
secretion by cellGO:00329402480.049
muscle structure developmentGO:0061061870.049
regulation of neuron differentiationGO:00456642080.048
Fly
eye morphogenesisGO:004859240.048
Fly
brain developmentGO:00074202470.048
macromolecule localizationGO:00330362520.047
Fly
cellular response to endogenous stimulusGO:00714953770.047
cation transportGO:00068123820.046
cell cycleGO:00070491010.046
Fly
cellular response to stressGO:00335542690.046
peptide hormone secretionGO:0030072840.046
cellular catabolic processGO:00442482950.045
protein complex assemblyGO:00064612630.045
gamete generationGO:00072761240.045
Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.045
positive regulation of cyclic nucleotide metabolic processGO:0030801370.044
regulation of membrane potentialGO:00423911100.043
response to hypoxiaGO:00016662310.043
divalent inorganic cation homeostasisGO:00725071650.043
response to peptideGO:19016522920.042
female sex differentiationGO:0046660590.042
negative regulation of signalingGO:00230571570.042
response to decreased oxygen levelsGO:00362932370.041
response to oxidative stressGO:00069791860.041
localization of cellGO:00516742020.040
Human Mouse Rat
negative regulation of multicellular organismal processGO:00512412030.040
Human
positive regulation of cellular component organizationGO:00511302000.039
Mouse Fly
multicellular organismal reproductive processGO:00486092330.039
Fly
central nervous system developmentGO:00074173110.038
negative regulation of gene expressionGO:00106291990.038
response to corticosteroidGO:00319602350.038
regulation of hormone secretionGO:00468831060.038
cellular component biogenesisGO:00440853680.038
Mouse Fly
developmental process involved in reproductionGO:00030061590.037
Fly
development of primary female sexual characteristicsGO:0046545560.037
regulation of nucleic acid templated transcriptionGO:19035063800.037
signal releaseGO:00230611450.036
cell motilityGO:00488702020.035
Human Mouse Rat
negative regulation of metabolic processGO:00098923310.035
response to glucoseGO:00097491360.035
carbohydrate homeostasisGO:0033500750.035
positive regulation of transcription dna templatedGO:00458931970.034
regulation of cellular localizationGO:00603412630.033
cellular chemical homeostasisGO:00550822470.033
regulation of transcription dna templatedGO:00063553740.033
head developmentGO:00603222470.033
reproductive structure developmentGO:00486081280.032
organophosphate metabolic processGO:00196373700.032
positive regulation of gene expressionGO:00106282440.032
response to glucocorticoidGO:00513842230.032
cell projection organizationGO:00300303020.032
Mouse Fly
negative regulation of macromolecule biosynthetic processGO:00105581480.031
carbohydrate metabolic processGO:00059751300.031
response to luteinizing hormoneGO:003469950.031
cellular response to hormone stimulusGO:00328702470.031
response to monosaccharideGO:00342841590.031
cellular component morphogenesisGO:00329891550.031
Mouse Fly
positive regulation of response to stimulusGO:00485842850.031
Fly
apoptotic processGO:00069153810.030
Mouse
response to ketoneGO:19016541820.030
ion homeostasisGO:00508012120.030
regulation of neuron apoptotic processGO:0043523830.030
Mouse
response to anoxiaGO:003405940.030
cation homeostasisGO:00550801950.030
positive regulation of rna metabolic processGO:00512542030.030
neuron projection developmentGO:00311752730.030
Fly
response to oxygen levelsGO:00704822650.029
positive regulation of cell proliferationGO:00082842490.029
positive regulation of cell communicationGO:00106472710.029
nucleic acid templated transcriptionGO:00976593790.029
macromolecular complex subunit organizationGO:00439333390.029
Fly
regulation of cell differentiationGO:00455953200.029
Human Fly
neuron deathGO:00709971270.029
Mouse
negative regulation of cellular metabolic processGO:00313242810.028
single organism carbohydrate metabolic processGO:00447231180.028
cellular response to corticosteroid stimulusGO:0071384690.028
cellular response to steroid hormone stimulusGO:0071383930.027
calcium ion homeostasisGO:00550741620.027
tissue developmentGO:00098882520.027
Human Mouse Fly
male mating behaviorGO:006017930.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
sex differentiationGO:00075481130.026
g protein coupled receptor signaling pathwayGO:00071862420.026
regulation of intracellular signal transductionGO:19025312180.026
Rat
dna metabolic processGO:0006259960.026
purine nucleotide metabolic processGO:00061632290.026
hormone secretionGO:00468791150.026
cellular divalent inorganic cation homeostasisGO:00725031620.026
regulation of multicellular organismal developmentGO:20000263760.025
Human Fly
regulation of cellular protein metabolic processGO:00322682670.025
Fly
alternative mrna splicing via spliceosomeGO:000038040.025
chemical homeostasisGO:00488782920.025
immune system processGO:00023762040.025
Human
regulation of immune system processGO:00026821230.024
positive regulation of nucleotide biosynthetic processGO:0030810360.024
divalent metal ion transportGO:00708381320.024
negative regulation of nucleic acid templated transcriptionGO:19035071170.024
synaptic growth at neuromuscular junctionGO:005112410.024
negative regulation of cellular biosynthetic processGO:00313271610.024
negative regulation of cell deathGO:00605482290.024
Mouse
regulation of neuron projection developmentGO:00109751610.023
Fly
muscle tissue developmentGO:0060537580.023
neuron apoptotic processGO:0051402880.023
Mouse
response to carbohydrateGO:00097431830.023
cell cycle processGO:0022402570.023
Fly
positive regulation of secretionGO:00510471400.023
cellular response to lipidGO:00713962010.023
response to hexoseGO:00097461440.023
regulation of secretionGO:00510462240.023
regulation of cell projection organizationGO:00313441750.022
Fly
positive regulation of nucleotide metabolic processGO:0045981910.022
biological adhesionGO:00226101100.022
Human Mouse Fly
regulation of cell migrationGO:00303341280.022
negative regulation of response to stimulusGO:00485851550.022
negative regulation of transportGO:00510511360.022
Fly
peptide secretionGO:0002790860.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
mapk cascadeGO:00001651400.021
behaviorGO:00076102050.021
carbohydrate derivative metabolic processGO:19011353460.021
cellular carbohydrate metabolic processGO:0044262720.021
synaptic transmissionGO:00072682350.021
positive regulation of cell developmentGO:00107201760.021
female gonad developmentGO:0008585530.021
positive regulation of cytosolic calcium ion concentrationGO:00072041220.021
cell morphogenesisGO:00009021420.021
Mouse Fly
positive regulation of signalingGO:00230562700.021
positive regulation of cellular biosynthetic processGO:00313282950.021
neurological system processGO:00508772190.021
protein oligomerizationGO:00512591910.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
purine nucleotide biosynthetic processGO:0006164830.020
regulation of neuron deathGO:19012141150.020
Mouse
regulation of peptide hormone secretionGO:0090276800.020
regulation of ion transportGO:00432692450.020
regulation of carbohydrate metabolic processGO:0006109410.020
sympathetic nervous system developmentGO:004848510.020
lipid metabolic processGO:00066292830.020
calcium ion transportGO:00068161310.019
ras protein signal transductionGO:0007265290.019
forebrain developmentGO:0030900980.019
axis specificationGO:000979840.019
Fly
negative regulation of transcription dna templatedGO:00458921160.019
regulation of cellular catabolic processGO:00313291010.019
positive regulation of signal transductionGO:00099671750.019
glucose homeostasisGO:0042593750.019
cellular ion homeostasisGO:00068731840.019
positive regulation of calcium ion transportGO:0051928360.019
regulation of nervous system developmentGO:00519602640.019
Fly
cellular metal ion homeostasisGO:00068751720.019
regulation of homeostatic processGO:00328441010.019
regulation of programmed cell deathGO:00430673410.019
Mouse
cellular response to peptide hormone stimulusGO:00713751200.019
positive regulation of peptide hormone secretionGO:0090277500.019
regulation of anatomical structure morphogenesisGO:00226031410.019
Human Fly
vesicle mediated transportGO:00161921810.018
response to metal ionGO:00100382530.018
regulation of phosphate metabolic processGO:00192203490.018
Fly
catabolic processGO:00090563510.018
negative regulation of cellular protein metabolic processGO:00322691060.018
positive regulation of rna biosynthetic processGO:19026801970.018
cellular response to nitrogen compoundGO:19016992100.018
protein localizationGO:00081041910.018
Fly
cell adhesionGO:00071551100.018
Human Mouse
regulation of system processGO:00440572080.018
insulin secretionGO:0030073690.018
heart morphogenesisGO:000300730.018
positive regulation of transportGO:00510502450.018
negative regulation of cell communicationGO:00106481580.018
secretionGO:00469033070.018
defecationGO:003042110.018
positive regulation of catalytic activityGO:00430851840.017
positive regulation of neuron differentiationGO:00456661260.017
transmission of nerve impulseGO:0019226420.017
cellular response to hexose stimulusGO:0071331650.017
agingGO:00075682410.017
reactive oxygen species metabolic processGO:0072593370.017
negative regulation of protein metabolic processGO:00512481140.017
protein heterooligomerizationGO:0051291890.017
single organism cellular localizationGO:19025801020.017
response to radiationGO:00093141370.017
single organism behaviorGO:00447081300.017
actin filament based processGO:0030029860.017
Mouse Rat Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
sexual reproductionGO:00199531480.017
Fly
regulation of behaviorGO:0050795610.017
response to nutrient levelsGO:00316673700.016
small gtpase mediated signal transductionGO:0007264360.016
tube developmentGO:0035295890.016
Fly
hormone biosynthetic processGO:0042446250.016
single organism intracellular transportGO:19025821660.016
positive regulation of ion transportGO:0043270940.016
response to ethanolGO:00454711620.016
response to vitaminGO:00332731310.016
cellular response to organic cyclic compoundGO:00714072020.016
positive regulation of developmental processGO:00510942830.016
positive regulation of secretion by cellGO:19035321280.016
regulation of molecular functionGO:00650093980.016
positive regulation of behaviorGO:0048520380.016
regulation of cell motilityGO:20001451310.016
female mating behaviorGO:006018060.015
leukocyte activationGO:0045321760.015
regulation of apoptotic processGO:00429813350.015
Mouse
cellular macromolecule localizationGO:00707271220.015
Fly
cellular response to glucose stimulusGO:0071333650.015
cellular ketone metabolic processGO:0042180510.015
neuron developmentGO:00486662860.015
Fly
purine ribonucleotide biosynthetic processGO:0009152810.015
cellular calcium ion homeostasisGO:00068741600.015
nucleotide metabolic processGO:00091172790.015
epithelial cell differentiationGO:0030855710.015
Human Mouse Fly
regulation of peptide secretionGO:0002791820.015
response to cytokineGO:00340972150.015
growthGO:00400071650.015
Fly
single organism organelle organizationGO:19025891800.015
Mouse Rat Fly
positive regulation of molecular functionGO:00440932300.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
response to ionizing radiationGO:0010212590.015
regulation of blood vessel sizeGO:0050880890.015
regulation of peptide transportGO:0090087870.015
positive regulation of camp metabolic processGO:0030816310.015
regulation of anatomical structure sizeGO:00900661350.015
regulation of calcium ion transportGO:0051924770.015
sequestering of calcium ionGO:005120880.015
hormone metabolic processGO:0042445690.015
positive regulation of cellular amine metabolic processGO:003324030.015
cellular response to alcoholGO:0097306870.015
proteolysisGO:00065081750.015
cytoplasmic transportGO:00164821150.014
cellular cation homeostasisGO:00300031800.014
regulation of catalytic activityGO:00507903040.014
single organism biosynthetic processGO:00447113420.014
maintenance of locationGO:0051235170.014
Fly
nucleobase containing small molecule metabolic processGO:00550863160.014
response to growth factorGO:00708481890.014
regulation of phosphorus metabolic processGO:00511743490.014
Fly
dephosphorylationGO:0016311980.014
exploration behaviorGO:003564010.014
cellular amino acid metabolic processGO:00065201070.014
developmental growthGO:00485891000.014
Fly
negative regulation of secretionGO:0051048820.014
positive regulation of purine nucleotide biosynthetic processGO:1900373360.014
gonad developmentGO:00084061040.014
cellular response to insulin stimulusGO:0032869810.014
regulation of dna metabolic processGO:0051052600.014
establishment of protein localizationGO:00451841410.014
Fly
nucleoside phosphate metabolic processGO:00067532830.014
positive regulation of intracellular signal transductionGO:19025331380.014
anterior posterior pattern specificationGO:000995210.014
meiotic cell cycle processGO:190304630.014
embryonic pattern specificationGO:000988010.014
chromosome organizationGO:0051276360.014
oxidation reduction processGO:00551143040.014
muscle cell differentiationGO:0042692520.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
rhythmic processGO:00485111560.014
development of primary sexual characteristicsGO:00451371070.013
circulatory system developmentGO:00723591340.013
Human
negative regulation of biosynthetic processGO:00098901680.013
regulation of defense responseGO:0031347680.013
positive regulation of hormone secretionGO:0046887650.013
kidney developmentGO:0001822670.013
amide transportGO:00428861050.013
positive regulation of cell migrationGO:0030335960.013
metal ion transportGO:00300012890.013
organ regenerationGO:00311001010.013
circulatory system processGO:00030131830.013
male gamete generationGO:0048232990.013
dendrite developmentGO:0016358720.013
regulation of nucleotide metabolic processGO:00061401170.013
negative regulation of secretion by cellGO:1903531720.013
organophosphate biosynthetic processGO:00904071430.013
purine containing compound biosynthetic processGO:0072522850.013
regulation of response to external stimulusGO:00321011060.013
multi multicellular organism processGO:00447061380.013
cell activationGO:0001775970.013
cellular response to external stimulusGO:00714961180.013
cell cycle checkpointGO:000007520.013
programmed cell deathGO:00125013920.013
Mouse
erk1 and erk2 cascadeGO:0070371480.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
b cell differentiationGO:003018320.012
steroid metabolic processGO:0008202730.012
deoxyribose phosphate metabolic processGO:001969290.012
regulation of protein metabolic processGO:00512462890.012
Fly
camera type eye morphogenesisGO:004859320.012
regulation of protein serine threonine kinase activityGO:0071900640.012
response to nutrientGO:00075842480.012
spermatogenesisGO:0007283990.012
positive regulation of locomotionGO:00400171020.012
smooth muscle cell apoptotic processGO:003439070.012
regulation of small gtpase mediated signal transductionGO:0051056480.012
Rat
ribose phosphate metabolic processGO:00196932350.012
gastrulationGO:000736920.012
Fly
positive regulation of endothelial cell migrationGO:001059540.012
dna integrity checkpointGO:003157020.012
heart developmentGO:0007507720.012
positive regulation of neurogenesisGO:00507691650.012
ribonucleotide biosynthetic processGO:0009260850.012
positive regulation of phosphorylationGO:00423271770.011
cardiovascular system developmentGO:00723581340.011
Human
regulation of catabolic processGO:00098941130.011
negative regulation of rna metabolic processGO:00512531230.011
cell cell signalingGO:00072673350.011
cellular response to carbohydrate stimulusGO:0071322720.011
urogenital system developmentGO:0001655780.011
cytosolic calcium ion homeostasisGO:00514801400.011
sensory perceptionGO:00076001010.011
negative regulation of neuron deathGO:1901215690.011
Mouse
cellular response to abiotic stimulusGO:0071214850.011
cellular lipid metabolic processGO:00442552080.011
response to reactive oxygen speciesGO:00003021200.011
nucleoside phosphate biosynthetic processGO:19012931020.011
regulation of cellular ketone metabolic processGO:0010565270.011
mrna metabolic processGO:0016071200.011
regulation of cellular amino acid metabolic processGO:000652120.011
artery developmentGO:006084030.011
regulation of map kinase activityGO:0043405530.011
regulation of phosphorylationGO:00423252480.011
Fly
hormone transportGO:00099141210.011
regulation of purine nucleotide metabolic processGO:19005421150.011
metal ion homeostasisGO:00550651860.011
regulation of body fluid levelsGO:0050878900.011
limbic system developmentGO:0021761380.011
sequestering of metal ionGO:005123890.011
mitotic cell cycle processGO:1903047350.011
Fly
organ formationGO:004864530.011
regulation of tube sizeGO:0035150890.011
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.011
response to extracellular stimulusGO:00099913800.011
protein targetingGO:0006605610.011
negative regulation of luteinizing hormone secretionGO:003368540.011
regulation of signal transductionGO:00099663180.011
Rat Fly
regulation of insulin secretionGO:0050796650.011
positive regulation of neuron apoptotic processGO:0043525330.010
cellular response to monosaccharide stimulusGO:0071326670.010
regulation of lipid metabolic processGO:0019216680.010
response to fatty acidGO:0070542650.010
peptide transportGO:0015833970.010
cell growthGO:00160491040.010
cell morphogenesis involved in differentiationGO:00009041190.010
Mouse Fly
amine metabolic processGO:0009308380.010
positive regulation of cell differentiationGO:00455972170.010
cellular glucose homeostasisGO:0001678660.010
regulation of sodium ion transmembrane transporter activityGO:200064940.010
digestive system developmentGO:0055123410.010
Fly
cellular response to growth factor stimulusGO:00713631620.010
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.010

Rock1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.029
cancerDOID:16200.029
gastrointestinal system cancerDOID:311900.022
organ system cancerDOID:005068600.022
disease of anatomical entityDOID:700.022
retinal diseaseDOID:567900.022
eye and adnexa diseaseDOID:149200.022
eye diseaseDOID:561400.022
sensory system diseaseDOID:005015500.022
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.014
colorectal cancerDOID:925600.014
colon cancerDOID:21900.014
intestinal cancerDOID:1015500.014
large intestine cancerDOID:567200.014
colon carcinomaDOID:152000.014