Rattus norvegicus

71 known processes

Top1

topoisomerase (DNA) I

(Aliases: Ab2-086)

Top1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein complex subunit organizationGO:00718223020.130
reproductive processGO:00224143720.116
sexual reproductionGO:00199531480.104
growthGO:00400071650.096
synaptic growth at neuromuscular junctionGO:005112410.084
positive regulation of phosphorus metabolic processGO:00105622620.081
oxoacid metabolic processGO:00434362900.073
multi organism reproductive processGO:00447032620.067
reproductionGO:00000032450.062
receptor localization to synapseGO:009712020.062
axonogenesisGO:0007409710.059
axis specificationGO:000979840.057
regulation of protein modification processGO:00313991940.053
regulation of phosphate metabolic processGO:00192203490.053
intracellular signal transductionGO:00355563140.053
cellular amino acid metabolic processGO:00065201070.052
regulation of phosphorus metabolic processGO:00511743490.051
cell cycleGO:00070491010.051
macromolecular complex subunit organizationGO:00439333390.049
protein phosphorylationGO:00064683450.049
response to extracellular stimulusGO:00099913800.048
single organism reproductive processGO:00447022970.044
cell projection morphogenesisGO:00488581230.044
cellular protein localizationGO:00346131220.043
cellular component biogenesisGO:00440853680.040
homeostatic processGO:00425923310.040
positive regulation of growthGO:0045927550.040
cell projection organizationGO:00300303020.038
regulation of catalytic activityGO:00507903040.035
muscle contractionGO:0006936880.035
developmental process involved in reproductionGO:00030061590.034
organelle organizationGO:00069962660.034
carbohydrate derivative metabolic processGO:19011353460.034
nucleoside triphosphate catabolic processGO:00091431230.033
positive regulation of phosphorylationGO:00423271770.033
organic acid metabolic processGO:00060822920.033
response to alkaloidGO:00432791320.032
macromolecular complex assemblyGO:00650032730.032
positive regulation of response to stimulusGO:00485842850.032
multicellular organism reproductionGO:00325042330.031
cell part morphogenesisGO:00329901230.031
neuron projection developmentGO:00311752730.031
regulation of protein phosphorylationGO:00019321830.031
protein complex biogenesisGO:00702712630.030
positive regulation of signalingGO:00230562700.030
positive regulation of signal transductionGO:00099671750.029
actin filament based processGO:0030029860.029
neurological system processGO:00508772190.028
purine nucleotide metabolic processGO:00061632290.028
regulation of protein metabolic processGO:00512462890.028
positive regulation of cell communicationGO:00106472710.028
cation transportGO:00068123820.026
response to ethanolGO:00454711620.026
gamete generationGO:00072761240.026
vesicle mediated transportGO:00161921810.026
regulation of growthGO:00400081050.026
response to radiationGO:00093141370.026
negative regulation of cellular metabolic processGO:00313242810.026
regulation of molecular functionGO:00650093980.025
positive regulation of neurogenesisGO:00507691650.025
carboxylic acid metabolic processGO:00197522890.025
leukocyte activationGO:0045321760.025
regulation of intracellular signal transductionGO:19025312180.025
positive regulation of intracellular signal transductionGO:19025331380.024
locomotor rhythmGO:004547510.024
organ regenerationGO:00311001010.024
protein complex assemblyGO:00064612630.023
proteolysisGO:00065081750.023
microtubule organizing center organizationGO:003102310.023
cell morphogenesis involved in differentiationGO:00009041190.023
regulation of signal transductionGO:00099663180.023
negative regulation of receptor internalizationGO:000209120.022
neuron projection morphogenesisGO:00488121220.022
rna biosynthetic processGO:00327743800.022
multicellular organismal reproductive processGO:00486092330.022
regulation of cellular amino acid metabolic processGO:000652120.022
neuron differentiationGO:00301823680.021
divalent metal ion transportGO:00708381320.021
centrosome organizationGO:005129710.021
cellular response to stressGO:00335542690.021
neuron developmentGO:00486662860.021
behaviorGO:00076102050.021
cytoskeleton organizationGO:00070101110.021
axon developmentGO:0061564960.021
cellular amine metabolic processGO:0044106380.020
multicellular organism growthGO:003526410.020
gastrulationGO:000736920.020
cellular ion homeostasisGO:00068731840.020
muscle system processGO:00030121150.020
carbohydrate metabolic processGO:00059751300.020
chemical homeostasisGO:00488782920.020
protein oligomerizationGO:00512591910.020
positive regulation of phosphate metabolic processGO:00459372620.020
single organism behaviorGO:00447081300.020
meiotic cell cycle processGO:190304630.020
spindle organizationGO:000705120.020
ureteric bud developmentGO:0001657140.020
negative regulation of peptidase activityGO:0010466380.019
regulation of establishment of protein localizationGO:0070201690.019
positive regulation of gene expressionGO:00106282440.019
cellular catabolic processGO:00442482950.019
regulation of membrane potentialGO:00423911100.019
reproductive system developmentGO:00614581280.019
positive regulation of neuron differentiationGO:00456661260.019
cellular response to external stimulusGO:00714961180.018
regulation of apoptotic processGO:00429813350.018
positive regulation of neuron projection developmentGO:0010976990.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
regulation of phosphorylationGO:00423252480.018
cellular homeostasisGO:00197252520.018
positive regulation of cellular protein metabolic processGO:00322701670.018
cation homeostasisGO:00550801950.018
peristalsisGO:003043220.018
embryonic axis specificationGO:000057810.018
neuronal ion channel clusteringGO:004516130.018
anterior posterior pattern specificationGO:000995210.018
divalent inorganic cation homeostasisGO:00725071650.018
nucleoside phosphate metabolic processGO:00067532830.018
negative regulation of protein metabolic processGO:00512481140.017
regulation of cellular amine metabolic processGO:003323880.017
response to cytokineGO:00340972150.017
positive regulation of protein modification processGO:00314011420.017
cellular component movementGO:00069282480.017
regulation of immune system processGO:00026821230.017
cell morphogenesisGO:00009021420.017
amine metabolic processGO:0009308380.017
positive regulation of molecular functionGO:00440932300.016
negative regulation of apoptotic processGO:00430661810.016
multicellular organismal signalingGO:0035637440.016
response to nutrient levelsGO:00316673700.016
behavioral response to ethanolGO:004814910.016
small gtpase mediated signal transductionGO:0007264360.016
muscle structure developmentGO:0061061870.016
regulation of cellular localizationGO:00603412630.016
rna metabolic processGO:00160704060.016
lymphocyte activationGO:0046649430.016
transmembrane transportGO:00550854120.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
synaptic transmissionGO:00072682350.015
regulation of protein transportGO:0051223680.015
negative regulation of phagocytosisGO:005076540.015
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.015
regulation of nervous system developmentGO:00519602640.015
anatomical structure morphogenesisGO:00096532980.015
positive regulation of protein metabolic processGO:00512471780.015
regulation of cellular protein metabolic processGO:00322682670.015
ribose phosphate metabolic processGO:00196932350.014
dna metabolic processGO:0006259960.014
negative regulation of cellular biosynthetic processGO:00313271610.014
positive regulation of transportGO:00510502450.014
negative regulation of cell deathGO:00605482290.014
cell cycle processGO:0022402570.014
secretion by cellGO:00329402480.014
receptor clusteringGO:0043113130.014
regulation of rna biosynthetic processGO:20011413810.014
reproductive structure developmentGO:00486081280.014
negative regulation of gene expressionGO:00106291990.014
cell cell signalingGO:00072673350.013
calcium ion homeostasisGO:00550741620.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
metal ion homeostasisGO:00550651860.013
gland developmentGO:00487321550.013
regulation of nucleotide metabolic processGO:00061401170.013
negative regulation of arp2 3 complex mediated actin nucleationGO:003431610.013
positive regulation of protein kinase activityGO:0045860730.013
regulation of multicellular organismal developmentGO:20000263760.013
positive regulation of developmental growthGO:0048639290.013
brain developmentGO:00074202470.013
cellular response to endogenous stimulusGO:00714953770.013
negative regulation of lymphocyte activationGO:0051250100.013
dendrite morphogenesisGO:0048813430.013
head developmentGO:00603222470.013
regulation of cellular component organizationGO:00511283680.013
purine containing compound metabolic processGO:00725212530.013
cellular component assemblyGO:00226073600.013
positive regulation of cell proliferationGO:00082842490.013
regulation of cell proliferationGO:00421273590.013
cell motilityGO:00488702020.013
response to transition metal nanoparticleGO:19902671220.013
regulation of kinase activityGO:00435491170.013
positive regulation of biosynthetic processGO:00098913190.013
regulation of protein processingGO:0070613500.013
protein deubiquitinationGO:001657940.013
embryonic pattern specificationGO:000988010.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
actin cytoskeleton organizationGO:0030036730.012
biological adhesionGO:00226101100.012
positive regulation of multicellular organismal processGO:00512403870.012
organophosphate metabolic processGO:00196373700.012
regulation of neurogenesisGO:00507672470.012
dendritic spine organizationGO:0097061120.012
neurotransmitter gated ion channel clusteringGO:007257830.012
alpha amino acid metabolic processGO:1901605710.012
negative regulation of endopeptidase activityGO:0010951360.012
regulation of mapk cascadeGO:00434081160.012
potassium ion transportGO:0006813970.012
cellular macromolecular complex assemblyGO:0034622580.012
regulation of hormone levelsGO:00108171870.012
positive regulation of protein phosphorylationGO:00019341350.012
regulation of secretion by cellGO:19035302080.011
positive regulation of cellular amine metabolic processGO:003324030.011
response to testosteroneGO:0033574550.011
negative regulation of catalytic activityGO:00430861030.011
sensory perceptionGO:00076001010.011
negative regulation of proteolysisGO:0045861410.011
positive regulation of synapse assemblyGO:0051965120.011
negative regulation of macromolecule metabolic processGO:00106052600.011
deoxyribose phosphate metabolic processGO:001969290.011
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031060.011
transmission of nerve impulseGO:0019226420.011
secretionGO:00469033070.011
male gamete generationGO:0048232990.011
regulation of transferase activityGO:00513381230.011
cellular amino acid catabolic processGO:0009063210.011
embryo developmentGO:0009790490.011
regulation of programmed cell deathGO:00430673410.011
catabolic processGO:00090563510.011
locomotionGO:00400112370.011
cellular response to nitrogen compoundGO:19016992100.010
single organism biosynthetic processGO:00447113420.010
regulation of neuron differentiationGO:00456642080.010
neuron deathGO:00709971270.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
cellular component morphogenesisGO:00329891550.010
nucleotide metabolic processGO:00091172790.010
positive regulation of nervous system developmentGO:00519621780.010
positive regulation of mapk cascadeGO:0043410920.010
purine ribonucleoside metabolic processGO:00461281680.010
positive regulation of apoptotic processGO:00430651540.010
positive regulation of secretion by cellGO:19035321280.010
regenerationGO:00310991630.010
rho protein signal transductionGO:0007266110.010
positive regulation of transferase activityGO:0051347810.010
cellular process involved in reproduction in multicellular organismGO:0022412350.010

Top1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org