IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Dak

dihydroxyacetone kinase 2 homolog (S. cerevisiae)

(Aliases: RGD1311026,MGC114371)

RGD: 1311026
Ensembl: ENSRNOG00000020704
Entrez: 361730
UniProtKB: Q4KLZ6

Process Predictions
Disease Predictions

Dak biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
carboxylic acid metabolic process	GO:0019752	289	0.249
single organism biosynthetic process	GO:0044711	342	0.221
organic acid metabolic process	GO:0006082	292	0.210
oxoacid metabolic process	GO:0043436	290	0.169
alpha amino acid metabolic process	GO:1901605	71	0.165
single organism catabolic process	GO:0044712	283	0.165
cellular response to peptide hormone stimulus	GO:0071375	120	0.151
organic acid biosynthetic process	GO:0016053	83	0.095
nucleobase containing small molecule metabolic process	GO:0055086	316	0.093
carbohydrate metabolic process	GO:0005975	130	0.093
organophosphate metabolic process	GO:0019637	370	0.084
small molecule biosynthetic process	GO:0044283	124	0.082
response to hypoxia	GO:0001666	231	0.081
cellular response to peptide	GO:1901653	133	0.080
response to peptide	GO:1901652	292	0.078
organic substance catabolic process	GO:1901575	316	0.075
carbohydrate catabolic process	GO:0016052	40	0.074
response to decreased oxygen levels	GO:0036293	237	0.068
catabolic process	GO:0009056	351	0.064
response to monosaccharide	GO:0034284	159	0.061
cellular amino acid metabolic process	GO:0006520	107	0.061
cellular response to insulin stimulus	GO:0032869	81	0.061
oxidation reduction process	GO:0055114	304	0.059
ribose phosphate metabolic process	GO:0019693	235	0.056
purine nucleotide metabolic process	GO:0006163	229	0.055
nucleoside metabolic process	GO:0009116	179	0.054
neuron development	GO:0048666	286	0.054
single organism carbohydrate metabolic process	GO:0044723	118	0.054
cellular response to organonitrogen compound	GO:0071417	197	0.054
monosaccharide metabolic process	GO:0005996	61	0.054
purine ribonucleotide metabolic process	GO:0009150	227	0.051
response to extracellular stimulus	GO:0009991	380	0.051
purine containing compound metabolic process	GO:0072521	253	0.051
carbohydrate derivative metabolic process	GO:1901135	346	0.049
carboxylic acid biosynthetic process	GO:0046394	83	0.049
ribonucleotide metabolic process	GO:0009259	231	0.049
tissue development	GO:0009888	252	0.049
response to glucose	GO:0009749	136	0.046
urea metabolic process	GO:0019627	5	0.045
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.045
purine ribonucleoside metabolic process	GO:0046128	168	0.045
coenzyme metabolic process	GO:0006732	86	0.045
cellular response to hormone stimulus	GO:0032870	247	0.045
response to peptide hormone	GO:0043434	278	0.043
organelle organization	GO:0006996	266	0.043
cellular ketone metabolic process	GO:0042180	51	0.043
intestinal absorption	GO:0050892	3	0.042
response to hexose	GO:0009746	144	0.042
regulation of vesicle mediated transport	GO:0060627	81	0.041
regulation of phosphorus metabolic process	GO:0051174	349	0.041
monocarboxylic acid metabolic process	GO:0032787	152	0.040
programmed cell death	GO:0012501	392	0.039
response to estrogen	GO:0043627	232	0.039
atp metabolic process	GO:0046034	72	0.038
nitrogen cycle metabolic process	GO:0071941	5	0.037
nucleotide biosynthetic process	GO:0009165	98	0.037
generation of precursor metabolites and energy	GO:0006091	62	0.036
fatty acid metabolic process	GO:0006631	99	0.036
lipid metabolic process	GO:0006629	283	0.036
cellular catabolic process	GO:0044248	295	0.035
response to carbohydrate	GO:0009743	183	0.035
nucleoside phosphate metabolic process	GO:0006753	283	0.035
nucleoside phosphate biosynthetic process	GO:1901293	102	0.035
cellular response to oxygen containing compound	GO:1901701	386	0.034
organophosphate biosynthetic process	GO:0090407	143	0.034
ribonucleoside metabolic process	GO:0009119	174	0.033
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.033
multicellular organismal reproductive process	GO:0048609	233	0.033
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.033
response to purine containing compound	GO:0014074	126	0.033
single organism carbohydrate catabolic process	GO:0044724	40	0.032
glucose metabolic process	GO:0006006	52	0.032
nucleoside monophosphate metabolic process	GO:0009123	93	0.032
response to molecule of bacterial origin	GO:0002237	194	0.032
regulation of programmed cell death	GO:0043067	341	0.032
organonitrogen compound biosynthetic process	GO:1901566	167	0.031
negative regulation of metabolic process	GO:0009892	331	0.031
organic anion transport	GO:0015711	132	0.031
regulation of apoptotic process	GO:0042981	335	0.031
regulation of cell development	GO:0060284	263	0.031
purine nucleoside metabolic process	GO:0042278	169	0.031
organic cyclic compound catabolic process	GO:1901361	175	0.030
organonitrogen compound catabolic process	GO:1901565	179	0.030
monocarboxylic acid biosynthetic process	GO:0072330	48	0.030
carboxylic acid catabolic process	GO:0046395	49	0.030
nucleotide metabolic process	GO:0009117	279	0.030
cellular component biogenesis	GO:0044085	368	0.030
response to nutrient	GO:0007584	248	0.028
purine ribonucleotide biosynthetic process	GO:0009152	81	0.028
glycosyl compound metabolic process	GO:1901657	182	0.028
chromosome segregation	GO:0007059	2	0.027
response to oxygen levels	GO:0070482	265	0.027
regulation of catalytic activity	GO:0050790	304	0.027
heterocycle catabolic process	GO:0046700	167	0.027
positive regulation of response to stimulus	GO:0048584	285	0.026
cellular amine metabolic process	GO:0044106	38	0.026
cellular response to nitrogen compound	GO:1901699	210	0.026
cellular component assembly	GO:0022607	360	0.026
regulation of cellular component organization	GO:0051128	368	0.026
response to lipopolysaccharide	GO:0032496	191	0.026
regeneration	GO:0031099	163	0.026
response to insulin	GO:0032868	133	0.026
cofactor metabolic process	GO:0051186	95	0.026
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.025
alpha amino acid biosynthetic process	GO:1901607	23	0.025
reproductive process	GO:0022414	372	0.025
regulation of molecular function	GO:0065009	398	0.025
response to external biotic stimulus	GO:0043207	221	0.025
purine nucleotide biosynthetic process	GO:0006164	83	0.025
regulation of neurogenesis	GO:0050767	247	0.025
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.025
regulation of nervous system development	GO:0051960	264	0.024
gland development	GO:0048732	155	0.024
response to metal ion	GO:0010038	253	0.024
positive regulation of nervous system development	GO:0051962	178	0.024
positive regulation of phosphorus metabolic process	GO:0010562	262	0.024
regulation of cellular amino acid metabolic process	GO:0006521	2	0.023
actin filament based process	GO:0030029	86	0.023
response to nutrient levels	GO:0031667	370	0.023
nucleoside triphosphate metabolic process	GO:0009141	144	0.023
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.023
hormone metabolic process	GO:0042445	69	0.023
regulation of cellular ketone metabolic process	GO:0010565	27	0.023
positive regulation of cell death	GO:0010942	184	0.023
protein phosphorylation	GO:0006468	345	0.022
nucleotide catabolic process	GO:0009166	139	0.022
positive regulation of neurogenesis	GO:0050769	165	0.022
cellular response to endogenous stimulus	GO:0071495	377	0.021
cytoskeleton organization	GO:0007010	111	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.021
regulation of cellular amine metabolic process	GO:0033238	8	0.021
amine metabolic process	GO:0009308	38	0.021
response to organophosphorus	GO:0046683	102	0.021
response to camp	GO:0051591	91	0.021
hexose metabolic process	GO:0019318	58	0.021
response to bacterium	GO:0009617	200	0.021
epithelium development	GO:0060429	96	0.021
hepaticobiliary system development	GO:0061008	90	0.021
ribonucleotide biosynthetic process	GO:0009260	85	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.020
positive regulation of developmental process	GO:0051094	283	0.020
transmembrane transport	GO:0055085	412	0.020
protein oligomerization	GO:0051259	191	0.020
cellular nitrogen compound catabolic process	GO:0044270	163	0.020
macromolecule localization	GO:0033036	252	0.019
regulation of phosphate metabolic process	GO:0019220	349	0.019
positive regulation of cellular biosynthetic process	GO:0031328	295	0.019
cellular amino acid biosynthetic process	GO:0008652	32	0.019
establishment of protein localization	GO:0045184	141	0.019
regulation of nucleotide metabolic process	GO:0006140	117	0.019
positive regulation of cellular amine metabolic process	GO:0033240	3	0.019
regulation of signal transduction	GO:0009966	318	0.019
nicotinamide nucleotide metabolic process	GO:0046496	28	0.018
aromatic compound catabolic process	GO:0019439	168	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.018
macromolecular complex subunit organization	GO:0043933	339	0.018
positive regulation of phosphorylation	GO:0042327	177	0.018
response to wounding	GO:0009611	254	0.018
neuron projection development	GO:0031175	273	0.018
liver development	GO:0001889	90	0.018
regulation of neuron projection development	GO:0010975	161	0.018
neuron differentiation	GO:0030182	368	0.018
positive regulation of cell development	GO:0010720	176	0.017
cellular response to external stimulus	GO:0071496	118	0.017
organic acid catabolic process	GO:0016054	49	0.017
multi organism reproductive process	GO:0044703	262	0.017
cell projection morphogenesis	GO:0048858	123	0.017
positive regulation of catalytic activity	GO:0043085	184	0.017
positive regulation of multicellular organismal process	GO:0051240	387	0.017
cellular amino acid catabolic process	GO:0009063	21	0.017
ras protein signal transduction	GO:0007265	29	0.017
organ morphogenesis	GO:0009887	75	0.017
response to inorganic substance	GO:0010035	377	0.017
cellular carbohydrate metabolic process	GO:0044262	72	0.017
ribose phosphate biosynthetic process	GO:0046390	87	0.017
glycosyl compound catabolic process	GO:1901658	126	0.017
protein complex biogenesis	GO:0070271	263	0.017
cellular response to cytokine stimulus	GO:0071345	127	0.017
cellular modified amino acid metabolic process	GO:0006575	61	0.017
response to ketone	GO:1901654	182	0.017
response to glucocorticoid	GO:0051384	223	0.016
positive regulation of programmed cell death	GO:0043068	157	0.016
olfactory behavior	GO:0042048	2	0.016
rna metabolic process	GO:0016070	406	0.016
macromolecular complex assembly	GO:0065003	273	0.016
purine containing compound biosynthetic process	GO:0072522	85	0.016
regulation of cellular protein metabolic process	GO:0032268	267	0.016
lipid catabolic process	GO:0016042	46	0.016
lipid biosynthetic process	GO:0008610	128	0.016
purine containing compound catabolic process	GO:0072523	138	0.016
reproductive structure development	GO:0048608	128	0.016
positive regulation of neuron projection development	GO:0010976	99	0.016
positive regulation of cell differentiation	GO:0045597	217	0.016
positive regulation of cellular component organization	GO:0051130	200	0.016
regulation of cell projection organization	GO:0031344	175	0.016
nucleoside monophosphate biosynthetic process	GO:0009124	28	0.016
vesicle mediated transport	GO:0016192	181	0.016
anatomical structure morphogenesis	GO:0009653	298	0.016
oligopeptide transport	GO:0006857	4	0.016
nucleobase containing compound catabolic process	GO:0034655	152	0.015
homeostatic process	GO:0042592	331	0.015
regulation of hydrolase activity	GO:0051336	143	0.015
negative regulation of innate immune response	GO:0045824	4	0.015
intracellular transport	GO:0046907	185	0.015
response to estradiol	GO:0032355	164	0.015
apoptotic process	GO:0006915	381	0.015
heart morphogenesis	GO:0003007	3	0.015
appendage morphogenesis	GO:0035107	4	0.015
chemical homeostasis	GO:0048878	292	0.015
isoprenoid metabolic process	GO:0006720	45	0.015
dna metabolic process	GO:0006259	96	0.015
regulation of purine nucleotide metabolic process	GO:1900542	115	0.015
toxin catabolic process	GO:0009407	1	0.015
protein complex assembly	GO:0006461	263	0.015
negative regulation of neurogenesis	GO:0050768	78	0.014
multicellular organism growth	GO:0035264	1	0.014
protein localization	GO:0008104	191	0.014
positive regulation of apoptotic process	GO:0043065	154	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.014
ribonucleotide catabolic process	GO:0009261	136	0.014
transcription from rna polymerase ii promoter	GO:0006366	252	0.014
cellular response to stress	GO:0033554	269	0.014
circadian rhythm	GO:0007623	88	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.014
reproduction	GO:0000003	245	0.014
biological adhesion	GO:0022610	110	0.014
regulation of hormone levels	GO:0010817	187	0.014
carbohydrate derivative catabolic process	GO:1901136	147	0.014
positive regulation of phosphate metabolic process	GO:0045937	262	0.014
intracellular protein transport	GO:0006886	79	0.014
single organism organelle organization	GO:1902589	180	0.014
purine nucleotide catabolic process	GO:0006195	136	0.014
regulation of transferase activity	GO:0051338	123	0.014
cellular hormone metabolic process	GO:0034754	49	0.014
olfactory learning	GO:0008355	1	0.014
rna biosynthetic process	GO:0032774	380	0.013
response to ethanol	GO:0045471	162	0.013
negative regulation of biosynthetic process	GO:0009890	168	0.013
regulation of kinase activity	GO:0043549	117	0.013
monocarboxylic acid catabolic process	GO:0072329	28	0.013
mapk cascade	GO:0000165	140	0.013
regulation of protein phosphorylation	GO:0001932	183	0.013
acrosome assembly	GO:0001675	3	0.013
regulation of catabolic process	GO:0009894	113	0.013
protein homooligomerization	GO:0051260	91	0.013
endocytosis	GO:0006897	84	0.013
meiotic cell cycle process	GO:1903046	3	0.013
nucleoside phosphate catabolic process	GO:1901292	140	0.013
embryo development	GO:0009790	49	0.013
cellular component morphogenesis	GO:0032989	155	0.013
response to oxidative stress	GO:0006979	186	0.013
regulation of protein metabolic process	GO:0051246	289	0.013
cellular response to oxidative stress	GO:0034599	76	0.013
cellular lipid metabolic process	GO:0044255	208	0.013
regulation of phosphorylation	GO:0042325	248	0.013
regulation of neuron death	GO:1901214	115	0.013
negative regulation of cellular metabolic process	GO:0031324	281	0.013
embryonic skeletal system morphogenesis	GO:0048704	3	0.012
cell projection organization	GO:0030030	302	0.012
purine ribonucleoside biosynthetic process	GO:0046129	21	0.012
purine ribonucleotide catabolic process	GO:0009154	136	0.012
divalent metal ion transport	GO:0070838	132	0.012
response to vitamin	GO:0033273	131	0.012
dephosphorylation	GO:0016311	98	0.012
growth	GO:0040007	165	0.012
purine nucleoside monophosphate biosynthetic process	GO:0009127	20	0.012
negative regulation of cellular protein metabolic process	GO:0032269	106	0.012
multicellular organism reproduction	GO:0032504	233	0.012
nucleoside catabolic process	GO:0009164	126	0.012
anion transport	GO:0006820	178	0.012
cellular macromolecule localization	GO:0070727	122	0.012
response to temperature stimulus	GO:0009266	94	0.012
cell adhesion	GO:0007155	110	0.012
positive regulation of gene expression	GO:0010628	244	0.012
lipid storage	GO:0019915	1	0.012
chemosensory behavior	GO:0007635	2	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.012
metal ion transport	GO:0030001	289	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.012
purine nucleoside catabolic process	GO:0006152	124	0.012
positive regulation of cell projection organization	GO:0031346	111	0.012
second messenger mediated signaling	GO:0019932	51	0.012
axis specification	GO:0009798	4	0.011
cellular protein localization	GO:0034613	122	0.011
transmission of nerve impulse	GO:0019226	42	0.011
organophosphate catabolic process	GO:0046434	148	0.011
steroid biosynthetic process	GO:0006694	48	0.011
intracellular signal transduction	GO:0035556	314	0.011
purine ribonucleoside catabolic process	GO:0046130	124	0.011
positive regulation of molecular function	GO:0044093	230	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
cellular response to organic cyclic compound	GO:0071407	202	0.011
cell cycle	GO:0007049	101	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.011
vitamin transport	GO:0051180	14	0.011
response to transition metal nanoparticle	GO:1990267	122	0.011
ribonucleoside catabolic process	GO:0042454	126	0.011
positive regulation of biosynthetic process	GO:0009891	319	0.011
response to radiation	GO:0009314	137	0.011
positive regulation of protein phosphorylation	GO:0001934	135	0.011
negative regulation of cell communication	GO:0010648	158	0.011
regulation of cell growth	GO:0001558	85	0.011
response to other organism	GO:0051707	220	0.011
central nervous system development	GO:0007417	311	0.011
regulation of carbohydrate metabolic process	GO:0006109	41	0.011
regulation of cell proliferation	GO:0042127	359	0.011
regulation of intracellular signal transduction	GO:1902531	218	0.011
carboxylic acid transport	GO:0046942	115	0.011
negative regulation of response to stimulus	GO:0048585	155	0.011
cellular response to reactive oxygen species	GO:0034614	55	0.011
regulation of anatomical structure size	GO:0090066	135	0.011
negative regulation of macromolecule metabolic process	GO:0010605	260	0.010
anterior posterior pattern specification	GO:0009952	1	0.010
actin cytoskeleton organization	GO:0030036	73	0.010
negative regulation of cell proliferation	GO:0008285	119	0.010
negative regulation of gene expression	GO:0010629	199	0.010
positive regulation of protein metabolic process	GO:0051247	178	0.010
positive regulation of intracellular signal transduction	GO:1902533	138	0.010
regulation of nucleic acid templated transcription	GO:1903506	380	0.010
limb morphogenesis	GO:0035108	4	0.010
ornithine metabolic process	GO:0006591	3	0.010
pyruvate metabolic process	GO:0006090	27	0.010
nucleic acid templated transcription	GO:0097659	379	0.010
developmental process involved in reproduction	GO:0003006	159	0.010
positive regulation of signaling	GO:0023056	270	0.010
multicellular organismal signaling	GO:0035637	44	0.010
lipid oxidation	GO:0034440	30	0.010
brain development	GO:0007420	247	0.010
response to biotic stimulus	GO:0009607	226	0.010
cellular homeostasis	GO:0019725	252	0.010

Dak disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.023
musculoskeletal system disease	DOID:17	0.023
disease of metabolism	DOID:0014667	0.017
inherited metabolic disorder	DOID:655	0.017
cardiovascular system disease	DOID:1287	0.012

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IMP

Rattus norvegicus

Dak

Dak biological process predictions

Dak disease predictions

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