Rattus norvegicus

49 known processes

Kctd13

potassium channel tetramerisation domain containing 13

Kctd13 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cell communicationGO:00106472710.317
single organism membrane organizationGO:0044802740.252
cellular macromolecule localizationGO:00707271220.208
regulation of molecular functionGO:00650093980.207
regulation of ion transportGO:00432692450.198
exocytosisGO:0006887600.192
regulation of signal transductionGO:00099663180.181
negative regulation of biosynthetic processGO:00098901680.176
carbohydrate derivative metabolic processGO:19011353460.171
cyclic purine nucleotide metabolic processGO:0052652620.155
ribose phosphate biosynthetic processGO:0046390870.145
macromolecule localizationGO:00330362520.145
cellular protein localizationGO:00346131220.143
organic substance catabolic processGO:19015753160.142
negative regulation of cellular biosynthetic processGO:00313271610.138
purine nucleotide metabolic processGO:00061632290.136
regulation of nucleotide biosynthetic processGO:0030808470.133
positive regulation of phosphorus metabolic processGO:00105622620.131
ribonucleotide biosynthetic processGO:0009260850.128
negative regulation of cellular metabolic processGO:00313242810.128
regulation of phosphate metabolic processGO:00192203490.121
positive regulation of synaptic vesicle endocytosisGO:190024410.120
regulation of transmembrane transportGO:00347621220.118
single organism cellular localizationGO:19025801020.117
regulation of exocytosisGO:0017157370.117
establishment of protein localizationGO:00451841410.117
purine ribonucleotide metabolic processGO:00091502270.116
purine ribonucleotide biosynthetic processGO:0009152810.115
protein localizationGO:00081041910.111
purine containing compound metabolic processGO:00725212530.110
nucleoside phosphate metabolic processGO:00067532830.106
synaptic vesicle endocytosisGO:004848840.105
intracellular protein transportGO:0006886790.104
organophosphate metabolic processGO:00196373700.102
organonitrogen compound biosynthetic processGO:19015661670.100
central nervous system developmentGO:00074173110.099
intracellular transportGO:00469071850.099
regulation of cyclic nucleotide biosynthetic processGO:0030802450.099
purine nucleotide biosynthetic processGO:0006164830.098
ribonucleotide metabolic processGO:00092592310.097
regulation of cyclic nucleotide metabolic processGO:0030799510.097
glutamate receptor signaling pathwayGO:0007215430.096
regulation of phosphorylationGO:00423252480.095
ribose phosphate metabolic processGO:00196932350.095
response to nutrient levelsGO:00316673700.094
cyclic nucleotide metabolic processGO:0009187800.093
regulation of vesicle mediated transportGO:0060627810.093
single organism biosynthetic processGO:00447113420.084
nucleotide biosynthetic processGO:0009165980.082
regulation of kinase activityGO:00435491170.080
nucleobase containing small molecule metabolic processGO:00550863160.079
regulation of catalytic activityGO:00507903040.079
single organism behaviorGO:00447081300.079
intracellular signal transductionGO:00355563140.079
purine containing compound biosynthetic processGO:0072522850.078
synapse organizationGO:0050808460.076
oxoacid metabolic processGO:00434362900.075
positive regulation of synaptic transmissionGO:0050806620.074
positive regulation of transportGO:00510502450.073
negative regulation of metabolic processGO:00098923310.073
camp metabolic processGO:0046058630.073
protein transportGO:00150311320.073
negative regulation of nucleic acid templated transcriptionGO:19035071170.071
organophosphate biosynthetic processGO:00904071430.070
neuron projection developmentGO:00311752730.069
negative regulation of macromolecule biosynthetic processGO:00105581480.069
carbohydrate derivative biosynthetic processGO:19011371240.068
cyclic nucleotide biosynthetic processGO:0009190630.068
regulation of nucleotide metabolic processGO:00061401170.068
negative regulation of gene expressionGO:00106291990.067
regulation of phosphorus metabolic processGO:00511743490.067
vesicle mediated transportGO:00161921810.066
positive regulation of molecular functionGO:00440932300.066
learning or memoryGO:0007611900.065
synaptic vesicle exocytosisGO:0016079150.063
negative regulation of nucleobase containing compound metabolic processGO:00459341530.063
response to glucocorticoidGO:00513842230.063
cation transportGO:00068123820.063
regulation of transferase activityGO:00513381230.063
postsynaptic density protein 95 clusteringGO:009711920.062
regulation of multicellular organismal developmentGO:20000263760.062
regulation of cellular component organizationGO:00511283680.061
membrane organizationGO:0061024940.061
regulation of nucleic acid templated transcriptionGO:19035063800.061
divalent inorganic cation transportGO:00725111340.060
nucleotide catabolic processGO:00091661390.060
positive regulation of phosphate metabolic processGO:00459372620.059
cellular response to hormone stimulusGO:00328702470.058
negative regulation of response to stimulusGO:00485851550.057
regulation of rna biosynthetic processGO:20011413810.057
positive regulation of neuron projection developmentGO:0010976990.056
g protein coupled receptor signaling pathwayGO:00071862420.056
regulation of purine nucleotide biosynthetic processGO:1900371460.056
regulation of camp biosynthetic processGO:0030817380.055
regulation of intracellular signal transductionGO:19025312180.054
synaptic growth at neuromuscular junctionGO:005112410.054
regulation of synaptic vesicle endocytosisGO:190024210.054
positive regulation of cell developmentGO:00107201760.054
growthGO:00400071650.054
negative regulation of macromolecule metabolic processGO:00106052600.053
response to inorganic substanceGO:00100353770.053
regulation of secretion by cellGO:19035302080.053
positive regulation of purine nucleotide metabolic processGO:1900544910.052
positive regulation of multicellular organismal processGO:00512403870.051
regulation of neuron deathGO:19012141150.051
positive regulation of cellular amine metabolic processGO:003324030.051
regulation of ion transmembrane transporter activityGO:0032412480.051
adult locomotory behaviorGO:000834440.051
nucleoside phosphate biosynthetic processGO:19012931020.051
regulation of cellular amino acid metabolic processGO:000652120.050
inorganic cation transmembrane transportGO:00986622020.050
positive regulation of signalingGO:00230562700.049
regulation of transmembrane transporter activityGO:0022898490.048
negative regulation of transportGO:00510511360.048
synaptic vesicle localizationGO:0097479240.048
cellular response to oxygen containing compoundGO:19017013860.048
behaviorGO:00076102050.048
positive regulation of phosphorylationGO:00423271770.048
head developmentGO:00603222470.048
camp biosynthetic processGO:0006171470.047
neurotransmitter gated ion channel clusteringGO:007257830.047
organelle organizationGO:00069962660.047
long term synaptic potentiationGO:0060291210.047
regulation of rna metabolic processGO:00512523910.046
brain developmentGO:00074202470.046
regulation of cellular protein metabolic processGO:00322682670.046
cellular component biogenesisGO:00440853680.046
synaptic transmissionGO:00072682350.046
regulation of cellular localizationGO:00603412630.045
positive regulation of purine nucleotide biosynthetic processGO:1900373360.045
regulation of synaptic transmissionGO:00508041410.043
protein complex subunit organizationGO:00718223020.043
organelle localizationGO:0051640550.043
secretion by cellGO:00329402480.043
aromatic compound catabolic processGO:00194391680.043
rna biosynthetic processGO:00327743800.043
regulation of camp metabolic processGO:0030814430.042
nucleotide metabolic processGO:00091172790.042
divalent metal ion transportGO:00708381320.041
negative regulation of rna metabolic processGO:00512531230.041
regulation of transporter activityGO:0032409500.041
catabolic processGO:00090563510.041
regulation of ion transmembrane transportGO:00347651210.040
regulation of respiratory gaseous exchange by neurological system processGO:000208710.039
positive regulation of protein kinase activityGO:0045860730.039
negative regulation of nitrogen compound metabolic processGO:00511721610.039
calcium ion transportGO:00068161310.039
regulation of calcium ion transportGO:0051924770.039
regulation of protein phosphorylationGO:00019321830.039
cellular amino acid metabolic processGO:00065201070.038
positive regulation of cellular amino acid metabolic processGO:004576410.038
chemosensory behaviorGO:000763520.038
regulation of protein kinase activityGO:00458591050.038
positive regulation of synaptic vesicle recyclingGO:190342310.037
single organism intracellular transportGO:19025821660.037
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.037
single organism catabolic processGO:00447122830.037
regulation of cell developmentGO:00602842630.037
positive regulation of nucleotide metabolic processGO:0045981910.037
protein targetingGO:0006605610.037
regulation of purine nucleotide metabolic processGO:19005421150.037
regulation of respiratory system processGO:004406510.037
negative regulation of cellular component organizationGO:0051129830.036
regulation of lyase activityGO:0051339220.036
neuron differentiationGO:00301823680.036
positive regulation of nervous system developmentGO:00519621780.036
wound healingGO:00420601220.036
negative regulation of phosphorus metabolic processGO:0010563800.036
ion transmembrane transportGO:00342203650.035
regulation of synaptic plasticityGO:0048167700.035
transcription dna templatedGO:00063513770.035
protein localization to membraneGO:0072657360.035
regulation of cell differentiationGO:00455953200.034
response to oxidative stressGO:00069791860.034
nucleobase containing compound catabolic processGO:00346551520.034
reproductive processGO:00224143720.034
cognitionGO:0050890920.034
organic cyclic compound catabolic processGO:19013611750.034
purine ribonucleoside metabolic processGO:00461281680.033
organonitrogen compound catabolic processGO:19015651790.033
carboxylic acid metabolic processGO:00197522890.033
purine nucleoside metabolic processGO:00422781690.033
positive regulation of cell differentiationGO:00455972170.033
regulation of neuron projection developmentGO:00109751610.033
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711320.032
positive regulation of nitrogen compound metabolic processGO:00511733340.032
positive regulation of biosynthetic processGO:00098913190.032
response to radiationGO:00093141370.032
synaptic vesicle transportGO:0048489230.031
synapse assemblyGO:0007416290.031
transmembrane transportGO:00550854120.031
positive regulation of cellular biosynthetic processGO:00313282950.030
cation transmembrane transportGO:00986552630.030
positive regulation of synaptic vesicle transportGO:190280530.030
cellular nitrogen compound catabolic processGO:00442701630.030
positive regulation of secretionGO:00510471400.030
cellular response to stressGO:00335542690.030
cellular component assemblyGO:00226073600.030
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.030
negative regulation of cellular protein metabolic processGO:00322691060.030
lipid metabolic processGO:00066292830.030
response to ethanolGO:00454711620.029
n methyl d aspartate receptor clusteringGO:009711420.029
regulation of neurotransmitter secretionGO:0046928190.029
rna metabolic processGO:00160704060.029
cellular ketone metabolic processGO:0042180510.029
negative regulation of transcription dna templatedGO:00458921160.028
regulation of nervous system developmentGO:00519602640.028
purine ribonucleoside monophosphate metabolic processGO:0009167840.028
ras protein signal transductionGO:0007265290.028
regulation of protein metabolic processGO:00512462890.028
negative regulation of axon guidanceGO:190266830.028
positive regulation of cellular component organizationGO:00511302000.028
positive regulation of protein metabolic processGO:00512471780.028
positive regulation of programmed cell deathGO:00430681570.027
regulation of transcription dna templatedGO:00063553740.027
protein complex assemblyGO:00064612630.027
embryonic pattern specificationGO:000988010.027
positive regulation of neuron differentiationGO:00456661260.027
olfactory behaviorGO:004204820.027
positive regulation of apoptotic processGO:00430651540.026
cellular response to endogenous stimulusGO:00714953770.026
secretionGO:00469033070.026
cytoplasmic transportGO:00164821150.026
regulation of neuron differentiationGO:00456642080.026
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031060.026
nucleic acid templated transcriptionGO:00976593790.026
regulation of neurotransmitter levelsGO:0001505420.025
small gtpase mediated signal transductionGO:0007264360.025
cell cell signalingGO:00072673350.025
programmed cell deathGO:00125013920.025
negative regulation of phosphate metabolic processGO:0045936800.025
negative regulation of signalingGO:00230571570.025
protein phosphorylationGO:00064683450.024
mapk cascadeGO:00001651400.024
axis specificationGO:000979840.024
somatostatin receptor signaling pathwayGO:003816940.024
vesicle organizationGO:0016050290.024
nucleoside metabolic processGO:00091161790.024
positive regulation of developmental processGO:00510942830.024
positive regulation of camp metabolic processGO:0030816310.024
regulation of membrane potentialGO:00423911100.024
positive regulation of cyclic nucleotide metabolic processGO:0030801370.024
protein localization to organelleGO:0033365570.024
negative regulation of rna biosynthetic processGO:19026791180.024
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.023
cell morphogenesis involved in differentiationGO:00009041190.023
negative regulation of camp metabolic processGO:0030815140.023
positive regulation of protein phosphorylationGO:00019341350.023
positive regulation of organelle organizationGO:0010638480.023
protein complex biogenesisGO:00702712630.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
regulation of cellular ketone metabolic processGO:0010565270.022
establishment of organelle localizationGO:0051656370.022
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.022
cellular catabolic processGO:00442482950.022
asymmetric protein localizationGO:000810520.022
ribonucleoside monophosphate metabolic processGO:0009161880.022
single organism organelle organizationGO:19025891800.022
response to growth factorGO:00708481890.022
membrane depolarizationGO:0051899320.022
positive regulation of intracellular signal transductionGO:19025331380.021
purine ribonucleoside catabolic processGO:00461301240.021
embryonic axis specificationGO:000057810.021
regulation of apoptotic processGO:00429813350.021
positive regulation of catalytic activityGO:00430851840.021
regulation of catabolic processGO:00098941130.021
ribonucleoside metabolic processGO:00091191740.021
organophosphate catabolic processGO:00464341480.021
nucleoside triphosphate catabolic processGO:00091431230.021
regulation of inhibitory postsynaptic membrane potentialGO:006008060.021
inorganic ion transmembrane transportGO:00986602290.020
macromolecular complex assemblyGO:00650032730.020
positive regulation of kinase activityGO:0033674770.020
positive regulation of transferase activityGO:0051347810.020
generation of precursor metabolites and energyGO:0006091620.020
calcium ion transmembrane transportGO:0070588700.020
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.020
monocarboxylic acid metabolic processGO:00327871520.020
postsynaptic membrane organizationGO:000194150.020
positive regulation of mapk cascadeGO:0043410920.020
neurotransmitter secretionGO:0007269330.020
response to glucoseGO:00097491360.020
nucleoside catabolic processGO:00091641260.020
organic acid metabolic processGO:00060822920.019
response to cytokineGO:00340972150.019
cellular lipid metabolic processGO:00442552080.019
neuron developmentGO:00486662860.019
olfactory learningGO:000835510.019
regulation of the force of heart contraction by chemical signalGO:000305720.019
regulation of synaptic vesicle recyclingGO:190342110.019
regulation of cellular amine metabolic processGO:003323880.019
glycosyl compound catabolic processGO:19016581260.018
gliogenesisGO:0042063930.018
atp catabolic processGO:0006200540.018
response to corticosteroidGO:00319602350.018
carbohydrate derivative catabolic processGO:19011361470.018
muscle contractionGO:0006936880.018
heterocycle catabolic processGO:00467001670.018
regulation of cyclase activityGO:0031279210.018
positive regulation of nucleotide biosynthetic processGO:0030810360.018
positive regulation of cellular protein metabolic processGO:00322701670.018
purine nucleotide catabolic processGO:00061951360.018
positive regulation of exocytosisGO:0045921190.018
response to estrogenGO:00436272320.018
vesicle localizationGO:0051648330.018
neurological system processGO:00508772190.017
response to extracellular stimulusGO:00099913800.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
positive regulation of cell deathGO:00109421840.017
inflammatory responseGO:00069541500.017
phospholipase c activating serotonin receptor signaling pathwayGO:000720820.017
regulation of adenylate cyclase activityGO:0045761180.017
neuron deathGO:00709971270.017
regulation of postsynaptic membrane potentialGO:0060078250.017
positive regulation of long term synaptic potentiationGO:190027340.017
cell projection organizationGO:00300303020.017
response to metal ionGO:00100382530.017
response to monosaccharideGO:00342841590.017
cgmp biosynthetic processGO:0006182150.017
apoptotic processGO:00069153810.017
negative regulation of neuron deathGO:1901215690.017
cellular homeostasisGO:00197252520.017
regulation of neurogenesisGO:00507672470.017
regulation of endocytosisGO:0030100420.017
positive regulation of transcription dna templatedGO:00458931970.017
positive regulation of protein modification processGO:00314011420.017
developmental growthGO:00485891000.016
nuclear transportGO:0051169490.016
negative regulation of multicellular organismal processGO:00512412030.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
respiratory system processGO:000301630.016
cell growthGO:00160491040.016
positive regulation of signal transductionGO:00099671750.016
regulation of metal ion transportGO:00109591180.016
negative regulation of cell developmentGO:0010721820.016
metal ion transportGO:00300012890.016
reproductionGO:00000032450.016
regulation of protein transportGO:0051223680.016
neurotransmitter transportGO:0006836420.016
regulation of programmed cell deathGO:00430673410.016
regenerationGO:00310991630.016
regulation of secretionGO:00510462240.016
cellular response to organonitrogen compoundGO:00714171970.016
amine metabolic processGO:0009308380.016
negative regulation of circadian sleep wake cycle non rem sleepGO:004232320.016
negative regulation of molecular functionGO:00440921330.016
negative regulation of protein metabolic processGO:00512481140.016
cellular amine metabolic processGO:0044106380.016
negative regulation of neuron differentiationGO:0045665620.015
macromolecular complex subunit organizationGO:00439333390.015
myeloid leukocyte activationGO:0002274360.015
regulation of cell growthGO:0001558850.015
regulation of excitatory postsynaptic membrane potentialGO:0060079180.015
single organism reproductive processGO:00447022970.015
positive regulation of response to stimulusGO:00485842850.015
ribonucleoside catabolic processGO:00424541260.015
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.015
positive regulation of growthGO:0045927550.015
response to hexoseGO:00097461440.015
phospholipid metabolic processGO:0006644610.015
regulation of glutamate receptor signaling pathwayGO:1900449170.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
purine containing compound catabolic processGO:00725231380.015
negative regulation of programmed cell deathGO:00430691830.015
regulation of receptor activityGO:0010469290.015
endocytosisGO:0006897840.015
motor neuron axon guidanceGO:000804510.015
response to carbohydrateGO:00097431830.015
negative regulation of cell deathGO:00605482290.014
forebrain developmentGO:0030900980.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
regulation of respiratory gaseous exchangeGO:004357620.014
detection of temperature stimulusGO:001604840.014
regulation of growthGO:00400081050.014
purine nucleoside catabolic processGO:00061521240.014
regulation of organelle organizationGO:0033043800.014
regulation of hydrolase activityGO:00513361430.014
positive regulation of secretion by cellGO:19035321280.014
protein oligomerizationGO:00512591910.014
neuron neuron synaptic transmissionGO:0007270600.014
macromolecule catabolic processGO:0009057580.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
regulation of nucleoside metabolic processGO:0009118660.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
serotonin receptor signaling pathwayGO:0007210100.014
purine nucleoside triphosphate catabolic processGO:00091461220.014
negative regulation of nervous system developmentGO:0051961790.013
multicellular organismal reproductive processGO:00486092330.013
glycosyl compound metabolic processGO:19016571820.013
regulation of cell proliferationGO:00421273590.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
respiratory gaseous exchangeGO:000758540.013
nucleoside phosphate catabolic processGO:19012921400.013
positive regulation of nucleotide catabolic processGO:0030813530.013
neuron apoptotic processGO:0051402880.013
positive regulation of neurotransmitter secretionGO:000195690.013
establishment of synaptic vesicle localizationGO:0097480230.013
cell part morphogenesisGO:00329901230.013
negative regulation of apoptotic processGO:00430661810.013
positive regulation of cell growthGO:0030307440.013
dna metabolic processGO:0006259960.013
synaptic vesicle recyclingGO:003646550.013
gtp catabolic processGO:0006184710.013
carboxylic acid transportGO:00469421150.013
regulation of tube sizeGO:0035150890.013
nucleoside triphosphate metabolic processGO:00091411440.012
dna integrity checkpointGO:003157020.012
multicellular organism reproductionGO:00325042330.012
positive regulation of neurogenesisGO:00507691650.012
oxidation reduction processGO:00551143040.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
negative regulation of catalytic activityGO:00430861030.012
regulation of dna metabolic processGO:0051052600.012
single organismal cell cell adhesionGO:0016337420.012
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.012
positive regulation of camp biosynthetic processGO:0030819280.012
neuronal ion channel clusteringGO:004516130.012
membrane fusionGO:0061025260.012
response to toxic substanceGO:00096361330.012
glycerolipid metabolic processGO:0046486670.012
cell projection morphogenesisGO:00488581230.012
regulation of purine nucleotide catabolic processGO:0033121650.011
nucleoside monophosphate catabolic processGO:0009125560.011
neuronal action potentialGO:0019228350.011
response to peptideGO:19016522920.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
g protein coupled acetylcholine receptor signaling pathwayGO:000721350.011
establishment of vesicle localizationGO:0051650310.011
regulation of axonogenesisGO:0050770370.011
regulation of erk1 and erk2 cascadeGO:0070372410.011
regulation of receptor mediated endocytosisGO:0048259170.011
receptor clusteringGO:0043113130.011
cellular response to growth factor stimulusGO:00713631620.011
positive regulation of renin secretion into blood streamGO:190013510.011
signal releaseGO:00230611450.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
regulation of protein modification processGO:00313991940.011
cell cycleGO:00070491010.011
negative regulation of purine nucleotide metabolic processGO:1900543230.011
positive regulation of lipid kinase activityGO:009021820.011
multi organism reproductive processGO:00447032620.011
neuromuscular processGO:005090520.011
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.011
developmental process involved in reproductionGO:00030061590.011
protein autophosphorylationGO:0046777660.011
establishment of protein localization to organelleGO:0072594440.011
organelle fusionGO:0048284170.010
glycogen metabolic processGO:0005977230.010
phosphatidylinositol dephosphorylationGO:004685640.010
regulation of synapse assemblyGO:0051963150.010
detection of temperature stimulus involved in sensory perception of painGO:005096540.010
energy derivation by oxidation of organic compoundsGO:0015980460.010
proteolysisGO:00065081750.010
positive regulation of ion transmembrane transportGO:0034767240.010
neuron projection extensionGO:1990138260.010
smooth muscle contractionGO:0006939370.010
somatostatin signaling pathwayGO:003817040.010
negative regulation of nucleotide metabolic processGO:0045980230.010
locomotory exploration behaviorGO:003564110.010
rhythmic synaptic transmissionGO:006002410.010
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.010
involuntary skeletal muscle contractionGO:000301120.010

Kctd13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.027
central nervous system diseaseDOID:33100.027
substance related disorderDOID:30300.017
disease of mental healthDOID:15000.017
substance dependenceDOID:997300.017