IMP: Integrative Multi-species Prediction

Rattus norvegicus

19 known processes

Dpysl4

dihydropyrimidinase-like 4

(Aliases: Crmp3,Dpys4)

RGD: 2409
Entrez: 25417
Ensembl: ENSRNOG00000027582
UniProtKB: Q62951
UniProtKB: F1LNT0

Process Predictions
Disease Predictions

Dpysl4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
neuron projection development	GO:0031175	273	0.128	Rat
neuron differentiation	GO:0030182	368	0.113
establishment of vesicle localization	GO:0051650	31	0.081	Rat
synaptic transmission	GO:0007268	235	0.076	Rat
neuron development	GO:0048666	286	0.075
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.066
cellular ketone metabolic process	GO:0042180	51	0.058
negative regulation of nervous system development	GO:0051961	79	0.057	Rat
protein oligomerization	GO:0051259	191	0.054	Rat
organic acid metabolic process	GO:0006082	292	0.053	Rat
oxoacid metabolic process	GO:0043436	290	0.052	Rat
macromolecular complex assembly	GO:0065003	273	0.050	Rat
regulation of cellular component organization	GO:0051128	368	0.047	Rat
central nervous system development	GO:0007417	311	0.047	Rat
positive regulation of transport	GO:0051050	245	0.043	Rat
transmembrane transport	GO:0055085	412	0.043
synaptic growth at neuromuscular junction	GO:0051124	1	0.042
brain development	GO:0007420	247	0.040	Rat
axon development	GO:0061564	96	0.040
establishment of synaptic vesicle localization	GO:0097480	23	0.039	Rat
carboxylic acid metabolic process	GO:0019752	289	0.039	Rat
aging	GO:0007568	241	0.038
response to inorganic substance	GO:0010035	377	0.037
cell cell signaling	GO:0007267	335	0.033	Rat
neurotransmitter transport	GO:0006836	42	0.033
nucleobase containing small molecule metabolic process	GO:0055086	316	0.032	Rat
cell morphogenesis involved in differentiation	GO:0000904	119	0.031
vesicle mediated transport	GO:0016192	181	0.031	Rat
regulation of nervous system development	GO:0051960	264	0.031	Rat
regulation of multicellular organismal development	GO:2000026	376	0.031	Rat
establishment of organelle localization	GO:0051656	37	0.030	Rat
positive regulation of cellular component organization	GO:0051130	200	0.030	Rat
learning or memory	GO:0007611	90	0.029
cell projection organization	GO:0030030	302	0.029	Rat
vitamin transport	GO:0051180	14	0.028
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.028
positive regulation of multicellular organismal process	GO:0051240	387	0.027	Rat
regulation of neurogenesis	GO:0050767	247	0.027	Rat
regulation of neuron projection development	GO:0010975	161	0.026	Rat
neurotransmitter secretion	GO:0007269	33	0.025
gliogenesis	GO:0042063	93	0.025
single organism biosynthetic process	GO:0044711	342	0.025
neuron projection morphogenesis	GO:0048812	122	0.024
negative regulation of neurogenesis	GO:0050768	78	0.024	Rat
regulation of locomotion	GO:0040012	148	0.024	Rat
regulation of synaptic transmission	GO:0050804	141	0.024
axis specification	GO:0009798	4	0.023
cellular component assembly	GO:0022607	360	0.023	Rat
regulation of synaptic plasticity	GO:0048167	70	0.023
response to glucocorticoid	GO:0051384	223	0.022
protein complex biogenesis	GO:0070271	263	0.022	Rat
regulation of cell projection organization	GO:0031344	175	0.022	Rat
regulation of phosphorus metabolic process	GO:0051174	349	0.022
cellular amino acid metabolic process	GO:0006520	107	0.022	Rat
motor neuron axon guidance	GO:0008045	1	0.022
vesicle localization	GO:0051648	33	0.022	Rat
neuromuscular synaptic transmission	GO:0007274	2	0.022
secretion	GO:0046903	307	0.022	Rat
regulation of cellular ketone metabolic process	GO:0010565	27	0.021
negative regulation of cell development	GO:0010721	82	0.021	Rat
cellular response to growth factor stimulus	GO:0071363	162	0.021
cation transport	GO:0006812	382	0.020
response to corticosteroid	GO:0031960	235	0.020
regulation of neurotransmitter levels	GO:0001505	42	0.020
negative regulation of multicellular organismal process	GO:0051241	203	0.020	Rat
synaptic vesicle transport	GO:0048489	23	0.020	Rat
cell projection morphogenesis	GO:0048858	123	0.019
positive regulation of cellular amine metabolic process	GO:0033240	3	0.019
positive regulation of neuron projection development	GO:0010976	99	0.019	Rat
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.019
positive regulation of nervous system development	GO:0051962	178	0.019	Rat
regulation of phosphate metabolic process	GO:0019220	349	0.018
heart morphogenesis	GO:0003007	3	0.018
axon guidance	GO:0007411	24	0.018
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.017
neuronal action potential	GO:0019228	35	0.017
monovalent inorganic cation transport	GO:0015672	172	0.017
head development	GO:0060322	247	0.017	Rat
regulation of vesicle mediated transport	GO:0060627	81	0.017
positive regulation of molecular function	GO:0044093	230	0.017
cellular response to oxygen containing compound	GO:1901701	386	0.017
cell cycle	GO:0007049	101	0.017
secretion by cell	GO:0032940	248	0.017	Rat
ion transmembrane transport	GO:0034220	365	0.017
dephosphorylation	GO:0016311	98	0.016
regulation of cell development	GO:0060284	263	0.016	Rat
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.016
response to growth factor	GO:0070848	189	0.016
cgmp biosynthetic process	GO:0006182	15	0.016
cellular component morphogenesis	GO:0032989	155	0.015
regulation of molecular function	GO:0065009	398	0.015
cell junction maintenance	GO:0034331	1	0.015
growth	GO:0040007	165	0.015
regulation of protein metabolic process	GO:0051246	289	0.015
regulation of cellular amine metabolic process	GO:0033238	8	0.015
adult locomotory behavior	GO:0008344	4	0.015
synaptic vesicle exocytosis	GO:0016079	15	0.014
protein heterooligomerization	GO:0051291	89	0.014
axonogenesis	GO:0007409	71	0.014
cellular chemical homeostasis	GO:0055082	247	0.014
carbohydrate derivative metabolic process	GO:1901135	346	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.014
neurological system process	GO:0050877	219	0.014
cell morphogenesis	GO:0000902	142	0.014
cellular response to hormone stimulus	GO:0032870	247	0.014
negative regulation of metabolic process	GO:0009892	331	0.014
protein phosphorylation	GO:0006468	345	0.014
organic hydroxy compound transport	GO:0015850	77	0.014
ribonucleotide metabolic process	GO:0009259	231	0.013
regulation of cellular amino acid metabolic process	GO:0006521	2	0.013
programmed cell death	GO:0012501	392	0.013
regulation of kinase activity	GO:0043549	117	0.013
single organism behavior	GO:0044708	130	0.013
reproductive process	GO:0022414	372	0.013
nucleotide metabolic process	GO:0009117	279	0.013
cellular homeostasis	GO:0019725	252	0.013
rna metabolic process	GO:0016070	406	0.013
monocarboxylic acid metabolic process	GO:0032787	152	0.013
regulation of cellular localization	GO:0060341	263	0.013	Rat
cellular component biogenesis	GO:0044085	368	0.013	Rat
positive regulation of neurogenesis	GO:0050769	165	0.013	Rat
regulation of anatomical structure morphogenesis	GO:0022603	141	0.013
signal release	GO:0023061	145	0.012
positive regulation of cell development	GO:0010720	176	0.012	Rat
anatomical structure morphogenesis	GO:0009653	298	0.012
positive regulation of cell projection organization	GO:0031346	111	0.012	Rat
macromolecular complex subunit organization	GO:0043933	339	0.012	Rat
negative regulation of neuron differentiation	GO:0045665	62	0.012	Rat
somatic stem cell division	GO:0048103	2	0.012
nucleoside phosphate metabolic process	GO:0006753	283	0.012
regulation of ion transport	GO:0043269	245	0.012	Rat
negative regulation of cellular metabolic process	GO:0031324	281	0.012
asymmetric stem cell division	GO:0098722	2	0.012
positive regulation of apoptotic process	GO:0043065	154	0.012
cation transmembrane transport	GO:0098655	263	0.012
regulation of rna biosynthetic process	GO:2001141	381	0.012
response to ketone	GO:1901654	182	0.012
protein complex subunit organization	GO:0071822	302	0.012	Rat
neuromuscular process	GO:0050905	2	0.012
male gamete generation	GO:0048232	99	0.012
activation of protein kinase b activity	GO:0032148	3	0.012
negative regulation of macromolecule metabolic process	GO:0010605	260	0.012
spermatogenesis	GO:0007283	99	0.012
positive regulation of cell death	GO:0010942	184	0.012
chemotaxis	GO:0006935	66	0.011
nucleoside metabolic process	GO:0009116	179	0.011
purine containing compound metabolic process	GO:0072521	253	0.011
regulation of rna metabolic process	GO:0051252	391	0.011
cellular component movement	GO:0006928	248	0.011	Rat
regulation of cell proliferation	GO:0042127	359	0.011
response to metal ion	GO:0010038	253	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.011
cell part morphogenesis	GO:0032990	123	0.011
positive regulation of programmed cell death	GO:0043068	157	0.011
regulation of neuron differentiation	GO:0045664	208	0.011	Rat
cytoskeleton dependent cytokinesis	GO:0061640	2	0.011
protein autophosphorylation	GO:0046777	66	0.011
developmental process involved in reproduction	GO:0003006	159	0.011
organophosphate metabolic process	GO:0019637	370	0.011
sexual reproduction	GO:0019953	148	0.011
positive regulation of neuron differentiation	GO:0045666	126	0.011	Rat
negative regulation of rna metabolic process	GO:0051253	123	0.011
organic substance catabolic process	GO:1901575	316	0.011	Rat
protein localization	GO:0008104	191	0.011
catabolic process	GO:0009056	351	0.011	Rat
negative regulation of developmental process	GO:0051093	125	0.011	Rat
transmission of nerve impulse	GO:0019226	42	0.011
cellular response to stress	GO:0033554	269	0.010
taxis	GO:0042330	67	0.010
response to vitamin	GO:0033273	131	0.010
intracellular signal transduction	GO:0035556	314	0.010
wound healing	GO:0042060	122	0.010
single organism reproductive process	GO:0044702	297	0.010
synapse assembly	GO:0007416	29	0.010
organic cyclic compound catabolic process	GO:1901361	175	0.010	Rat
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.010
exploration behavior	GO:0035640	1	0.010
mechanoreceptor differentiation	GO:0042490	2	0.010
spindle organization	GO:0007051	2	0.010
regulation of cell morphogenesis	GO:0022604	77	0.010
organonitrogen compound biosynthetic process	GO:1901566	167	0.010
response to acid chemical	GO:0001101	222	0.010
negative regulation of catalytic activity	GO:0043086	103	0.010
response to nutrient levels	GO:0031667	370	0.010
locomotion	GO:0040011	237	0.010	Rat

Dpysl4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.016
central nervous system disease	DOID:331	0.016
disease of anatomical entity	DOID:7	0.016
disease of mental health	DOID:150	0.015
substance related disorder	DOID:303	0.015

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