Rattus norvegicus

0 known processes

Sh2b1

SH2B adaptor protein 1

(Aliases: Sh2bpsm1,Sh2-b,Sh2b)

Sh2b1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nucleic acid templated transcriptionGO:19035063800.276
transcription dna templatedGO:00063513770.181
intracellular signal transductionGO:00355563140.176
regulation of rna biosynthetic processGO:20011413810.156
regulation of phosphorus metabolic processGO:00511743490.149
nucleic acid templated transcriptionGO:00976593790.134
rna biosynthetic processGO:00327743800.133
regulation of rna metabolic processGO:00512523910.130
positive regulation of signal transductionGO:00099671750.129
regulation of transcription dna templatedGO:00063553740.125
regulation of signal transductionGO:00099663180.125
rna metabolic processGO:00160704060.123
positive regulation of nitrogen compound metabolic processGO:00511733340.122
regulation of intracellular signal transductionGO:19025312180.118
positive regulation of gene expressionGO:00106282440.104
regulation of cellular localizationGO:00603412630.098
mapk cascadeGO:00001651400.091
transcription from rna polymerase ii promoterGO:00063662520.091
protein phosphorylationGO:00064683450.088
positive regulation of transcription dna templatedGO:00458931970.087
negative regulation of macromolecule metabolic processGO:00106052600.082
regulation of mapk cascadeGO:00434081160.078
regulation of phosphorylationGO:00423252480.073
regulation of phosphate metabolic processGO:00192203490.072
negative regulation of nitrogen compound metabolic processGO:00511721610.070
regulation of canonical wnt signaling pathwayGO:006082840.069
heart morphogenesisGO:000300730.066
positive regulation of signalingGO:00230562700.066
negative regulation of transcription dna templatedGO:00458921160.065
positive regulation of rna metabolic processGO:00512542030.062
negative regulation of cellular metabolic processGO:00313242810.062
tissue developmentGO:00098882520.062
positive regulation of intracellular signal transductionGO:19025331380.058
positive regulation of transferase activityGO:0051347810.057
regulation of protein modification processGO:00313991940.056
positive regulation of response to stimulusGO:00485842850.056
protein complex biogenesisGO:00702712630.053
neurological system processGO:00508772190.053
cellular response to endogenous stimulusGO:00714953770.053
signal transduction by phosphorylationGO:00230141440.052
regulation of system processGO:00440572080.051
establishment of tissue polarityGO:000716420.051
positive regulation of nucleobase containing compound metabolic processGO:00459353190.051
positive regulation of phosphorus metabolic processGO:00105622620.050
positive regulation of biosynthetic processGO:00098913190.049
organelle organizationGO:00069962660.049
protein localizationGO:00081041910.047
positive regulation of protein metabolic processGO:00512471780.047
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.047
negative regulation of cell communicationGO:00106481580.046
protein transportGO:00150311320.046
positive regulation of macromolecule biosynthetic processGO:00105572470.045
enzyme linked receptor protein signaling pathwayGO:00071671160.045
negative regulation of nucleic acid templated transcriptionGO:19035071170.045
positive regulation of phosphorylationGO:00423271770.045
multi multicellular organism processGO:00447061380.044
negative regulation of rna metabolic processGO:00512531230.044
negative regulation of gene expressionGO:00106291990.044
negative regulation of signalingGO:00230571570.044
regulation of transcription from rna polymerase ii promoterGO:00063572340.044
negative regulation of rna biosynthetic processGO:19026791180.040
positive regulation of secretion by cellGO:19035321280.040
negative regulation of cellular biosynthetic processGO:00313271610.040
positive regulation of nucleic acid templated transcriptionGO:19035081970.040
mesoderm developmentGO:000749820.039
negative regulation of signal transductionGO:0009968830.039
g protein coupled receptor signaling pathwayGO:00071862420.039
regulation of transferase activityGO:00513381230.039
regulation of kinase activityGO:00435491170.039
regulation of multicellular organismal developmentGO:20000263760.039
positive regulation of molecular functionGO:00440932300.038
regulation of molecular functionGO:00650093980.038
homeostatic processGO:00425923310.037
locomotionGO:00400112370.037
macromolecule localizationGO:00330362520.036
secretionGO:00469033070.036
positive regulation of cellular biosynthetic processGO:00313282950.036
anterior posterior pattern specificationGO:000995210.036
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.036
tube developmentGO:0035295890.036
regulation of cellular protein metabolic processGO:00322682670.036
single organism reproductive processGO:00447022970.035
immune system processGO:00023762040.035
positive regulation of multicellular organismal processGO:00512403870.035
cellular component movementGO:00069282480.035
cellular component assemblyGO:00226073600.034
positive regulation of phosphate metabolic processGO:00459372620.034
regulation of cell differentiationGO:00455953200.034
central nervous system developmentGO:00074173110.034
amine metabolic processGO:0009308380.034
positive regulation of transportGO:00510502450.034
positive regulation of cellular protein metabolic processGO:00322701670.034
positive regulation of protein phosphorylationGO:00019341350.034
negative regulation of metabolic processGO:00098923310.033
cellular amino acid metabolic processGO:00065201070.032
renal system developmentGO:0072001670.032
negative regulation of protein metabolic processGO:00512481140.032
negative regulation of cell differentiationGO:0045596990.032
digestive system developmentGO:0055123410.032
neuron projection developmentGO:00311752730.032
cellular response to oxygen containing compoundGO:19017013860.031
positive regulation of neurogenesisGO:00507691650.031
regulation of protein metabolic processGO:00512462890.031
response to metal ionGO:00100382530.031
transforming growth factor beta receptor signaling pathwayGO:0007179180.031
cell adhesionGO:00071551100.031
cell morphogenesis involved in differentiationGO:00009041190.031
positive regulation of nervous system developmentGO:00519621780.031
response to woundingGO:00096112540.030
cell cell signalingGO:00072673350.030
cellular component biogenesisGO:00440853680.030
cellular response to lipidGO:00713962010.030
proteolysisGO:00065081750.030
positive regulation of mapk cascadeGO:0043410920.029
negative regulation of multicellular organismal processGO:00512412030.029
peptidyl amino acid modificationGO:00181931260.029
secretion by cellGO:00329402480.028
regulation of protein phosphorylationGO:00019321830.028
positive regulation of protein modification processGO:00314011420.028
positive regulation of cellular component organizationGO:00511302000.028
neuron developmentGO:00486662860.028
regulation of protein kinase activityGO:00458591050.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.027
regulation of cell proliferationGO:00421273590.027
catabolic processGO:00090563510.027
establishment of protein localizationGO:00451841410.027
positive regulation of kinase activityGO:0033674770.026
protein complex assemblyGO:00064612630.026
cell projection organizationGO:00300303020.026
axon developmentGO:0061564960.026
neuron differentiationGO:00301823680.026
cellular amine metabolic processGO:0044106380.026
response to growth factorGO:00708481890.026
motor neuron axon guidanceGO:000804510.026
regulation of cellular amino acid metabolic processGO:000652120.025
regulation of map kinase activityGO:0043405530.025
positive regulation of protein kinase activityGO:0045860730.025
reproductive system developmentGO:00614581280.025
positive regulation of map kinase activityGO:0043406460.025
negative regulation of response to stimulusGO:00485851550.024
cellular response to growth factor stimulusGO:00713631620.024
positive regulation of rna biosynthetic processGO:19026801970.024
negative regulation of macromolecule biosynthetic processGO:00105581480.024
regulation of catalytic activityGO:00507903040.024
positive regulation of cell differentiationGO:00455972170.024
regulation of cell projection organizationGO:00313441750.024
negative regulation of transportGO:00510511360.024
tube formationGO:003514830.024
head developmentGO:00603222470.024
cardiovascular system developmentGO:00723581340.023
regulation of smooth muscle cell proliferationGO:0048660750.023
female pregnancyGO:00075651220.023
regulation of nucleotide metabolic processGO:00061401170.023
regulation of protein transportGO:0051223680.023
protein complex subunit organizationGO:00718223020.023
gastrulationGO:000736920.023
positive regulation of protein serine threonine kinase activityGO:0071902520.023
regulation of cellular amine metabolic processGO:003323880.022
regulation of cell developmentGO:00602842630.022
regulation of cellular ketone metabolic processGO:0010565270.022
organ morphogenesisGO:0009887750.022
muscle system processGO:00030121150.022
embryonic skeletal system developmentGO:004870630.022
response to ketoneGO:19016541820.022
negative regulation of developmental processGO:00510931250.022
single organism organelle organizationGO:19025891800.022
positive regulation of developmental processGO:00510942830.022
skeletal system developmentGO:0001501410.022
tube morphogenesisGO:0035239230.021
negative regulation of biosynthetic processGO:00098901680.021
response to estradiolGO:00323551640.021
single organism cellular localizationGO:19025801020.021
anatomical structure morphogenesisGO:00096532980.021
reproductive processGO:00224143720.021
synaptic transmissionGO:00072682350.021
neuron deathGO:00709971270.021
circulatory system processGO:00030131830.021
calcium ion homeostasisGO:00550741620.020
brain developmentGO:00074202470.020
negative regulation of cellular protein metabolic processGO:00322691060.020
oxoacid metabolic processGO:00434362900.020
organ formationGO:004864530.020
negative regulation of canonical wnt signaling pathwayGO:009009040.020
regulation of stem cell differentiationGO:200073620.020
blood circulationGO:00080151830.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
carboxylic acid metabolic processGO:00197522890.019
organic substance catabolic processGO:19015753160.019
multi organism reproductive processGO:00447032620.019
cellular protein localizationGO:00346131220.019
spindle organizationGO:000705120.019
cell type specific apoptotic processGO:00972851340.019
forebrain developmentGO:0030900980.019
inflammatory responseGO:00069541500.019
regulation of cellular catabolic processGO:00313291010.018
cellular response to hormone stimulusGO:00328702470.018
nuclear transportGO:0051169490.018
regulation of embryonic developmentGO:004599520.018
mitotic spindle organizationGO:000705220.018
response to cytokineGO:00340972150.018
vesicle mediated transportGO:00161921810.018
ribose phosphate metabolic processGO:00196932350.018
gliogenesisGO:0042063930.018
cellular response to peptideGO:19016531330.018
programmed cell deathGO:00125013920.018
epithelium developmentGO:0060429960.017
regulation of secretion by cellGO:19035302080.017
digestive tract developmentGO:0048565390.017
macromolecular complex subunit organizationGO:00439333390.017
regulation of homeostatic processGO:00328441010.017
cardiac chamber developmentGO:000320510.017
carbohydrate derivative metabolic processGO:19011353460.017
positive regulation of cell developmentGO:00107201760.017
regulation of programmed cell deathGO:00430673410.017
circulatory system developmentGO:00723591340.017
multicellular organismal reproductive processGO:00486092330.017
regulation of anatomical structure sizeGO:00900661350.017
positive regulation of catalytic activityGO:00430851840.017
response to inorganic substanceGO:00100353770.017
response to glucocorticoidGO:00513842230.017
cellular catabolic processGO:00442482950.017
organic acid metabolic processGO:00060822920.017
behaviorGO:00076102050.017
regulation of secretionGO:00510462240.016
response to peptide hormoneGO:00434342780.016
ras protein signal transductionGO:0007265290.016
axonogenesisGO:0007409710.016
heart developmentGO:0007507720.016
positive regulation of cell proliferationGO:00082842490.016
regulation of protein localizationGO:0032880810.016
regulation of apoptotic processGO:00429813350.016
gland developmentGO:00487321550.016
cognitionGO:0050890920.016
response to corticosteroidGO:00319602350.016
cellular calcium ion homeostasisGO:00068741600.016
regulation of establishment of protein localizationGO:0070201690.016
multicellular organism reproductionGO:00325042330.016
macromolecular complex assemblyGO:00650032730.016
wnt signaling pathway planar cell polarity pathwayGO:006007120.016
regulation of neuron projection developmentGO:00109751610.015
cellular response to organic cyclic compoundGO:00714072020.015
positive regulation of programmed cell deathGO:00430681570.015
agingGO:00075682410.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.015
response to acid chemicalGO:00011012220.015
negative regulation of molecular functionGO:00440921330.015
cellular ketone metabolic processGO:0042180510.015
reproductive structure developmentGO:00486081280.015
cellular response to stressGO:00335542690.015
mechanoreceptor differentiationGO:004249020.015
cellular component morphogenesisGO:00329891550.015
peptidyl tyrosine phosphorylationGO:0018108720.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
positive regulation of cellular amine metabolic processGO:003324030.015
taxisGO:0042330670.015
regulation of anatomical structure morphogenesisGO:00226031410.015
regulation of membrane potentialGO:00423911100.015
response to transforming growth factor betaGO:0071559460.014
neuron projection morphogenesisGO:00488121220.014
cytosolic calcium ion homeostasisGO:00514801400.014
glial cell differentiationGO:0010001650.014
purine containing compound metabolic processGO:00725212530.014
metal ion transportGO:00300012890.014
embryonic pattern specificationGO:000988010.014
regulation of protein import into nucleusGO:0042306240.014
purine ribonucleoside metabolic processGO:00461281680.014
regulation of neurogenesisGO:00507672470.014
purine nucleotide metabolic processGO:00061632290.014
cellular macromolecular complex assemblyGO:0034622580.014
cell fate determinationGO:000170920.014
embryonic skeletal system morphogenesisGO:004870430.014
inner ear receptor cell differentiationGO:006011320.014
cellular response to abiotic stimulusGO:0071214850.014
regulation of establishment of planar polarityGO:009017520.014
epithelial cell differentiationGO:0030855710.014
positive regulation of synaptic transmissionGO:0050806620.014
activation of protein kinase activityGO:0032147470.014
cellular response to organonitrogen compoundGO:00714171970.013
nucleosome organizationGO:003472810.013
biological adhesionGO:00226101100.013
cyclic nucleotide metabolic processGO:0009187800.013
cell motilityGO:00488702020.013
smooth muscle cell proliferationGO:0048659770.013
salivary gland developmentGO:000743130.013
regulation of nervous system developmentGO:00519602640.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
synaptic vesicle transportGO:0048489230.013
chromosome organizationGO:0051276360.013
cell part morphogenesisGO:00329901230.013
regulation of muscle contractionGO:0006937530.013
reproductionGO:00000032450.013
muscle organ morphogenesisGO:004864410.013
localization of cellGO:00516742020.013
protein localization to organelleGO:0033365570.013
protein targetingGO:0006605610.013
nucleotide biosynthetic processGO:0009165980.013
protein oligomerizationGO:00512591910.013
rhythmic processGO:00485111560.012
small gtpase mediated signal transductionGO:0007264360.012
protein autophosphorylationGO:0046777660.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
axis specificationGO:000979840.012
apoptotic processGO:00069153810.012
cell cycleGO:00070491010.012
positive regulation of apoptotic processGO:00430651540.012
response to radiationGO:00093141370.012
chemical homeostasisGO:00488782920.012
macromolecule catabolic processGO:0009057580.012
single organism membrane organizationGO:0044802740.012
regulation of nucleocytoplasmic transportGO:0046822280.012
divalent metal ion transportGO:00708381320.012
single organism intracellular transportGO:19025821660.012
single organism behaviorGO:00447081300.012
cell morphogenesisGO:00009021420.012
regulation of neuron apoptotic processGO:0043523830.012
non canonical wnt signaling pathwayGO:003556730.011
cardiac ventricle developmentGO:000323110.011
cellular response to nitrogen compoundGO:19016992100.011
protein import into nucleusGO:0006606350.011
nucleobase containing small molecule metabolic processGO:00550863160.011
positive regulation of neuron differentiationGO:00456661260.011
regulation of protein secretionGO:0050708280.011
negative regulation of cell deathGO:00605482290.011
muscle cell proliferationGO:0033002840.011
positive regulation of secretionGO:00510471400.011
cellular macromolecule localizationGO:00707271220.011
kidney developmentGO:0001822670.011
intracellular transportGO:00469071850.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
morphogenesis of embryonic epitheliumGO:001633130.011
cellular response to steroid hormone stimulusGO:0071383930.011
inner ear morphogenesisGO:004247210.011
cartilage developmentGO:0051216220.011
regulation of stress activated mapk cascadeGO:0032872230.011
nucleocytoplasmic transportGO:0006913480.011
nucleotide metabolic processGO:00091172790.011
regulation of protein serine threonine kinase activityGO:0071900640.011
purine ribonucleotide metabolic processGO:00091502270.011
regulation of b cell differentiationGO:004557710.011
regulation of blood vessel sizeGO:0050880890.011
sex differentiationGO:00075481130.011
gtp metabolic processGO:0046039720.011
cytoplasmic transportGO:00164821150.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
response to peptideGO:19016522920.011
cellular response to peptide hormone stimulusGO:00713751200.011
positive regulation of protein transportGO:0051222410.010
regulation of catabolic processGO:00098941130.010
response to dexamethasoneGO:0071548490.010
urogenital system developmentGO:0001655780.010
regulation of response to stressGO:00801341260.010
regulation of fat cell differentiationGO:004559830.010
peptidyl tyrosine modificationGO:0018212720.010
sensory organ developmentGO:0007423740.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
protein targeting to nucleusGO:0044744350.010
lipid metabolic processGO:00066292830.010
dephosphorylationGO:0016311980.010
positive regulation of cell projection organizationGO:00313461110.010
rna localizationGO:000640340.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
cellular chemical homeostasisGO:00550822470.010
protein secretionGO:0009306340.010
regulation of ion transportGO:00432692450.010

Sh2b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011
gastrointestinal system cancerDOID:311900.011