Rattus norvegicus

117 known processes

Keap1

Kelch-like ECH-associated protein 1

(Aliases: Inrf2)

Keap1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription dna templatedGO:00063513770.108
regulation of rna metabolic processGO:00512523910.094
rna biosynthetic processGO:00327743800.083
rna metabolic processGO:00160704060.068
purine ribonucleoside triphosphate metabolic processGO:00092051400.060
positive regulation of nitrogen compound metabolic processGO:00511733340.057
positive regulation of gene expressionGO:00106282440.055
organic substance catabolic processGO:19015753160.054
Human
regulation of apoptotic processGO:00429813350.053
positive regulation of cellular biosynthetic processGO:00313282950.049
cellular response to endogenous stimulusGO:00714953770.048
cellular response to hormone stimulusGO:00328702470.047
positive regulation of transcription dna templatedGO:00458931970.047
regulation of nucleic acid templated transcriptionGO:19035063800.046
regulation of rna biosynthetic processGO:20011413810.046
nucleotide metabolic processGO:00091172790.046
response to inorganic substanceGO:00100353770.045
regulation of transcription dna templatedGO:00063553740.045
ribonucleotide metabolic processGO:00092592310.045
nucleoside phosphate metabolic processGO:00067532830.043
purine nucleoside triphosphate catabolic processGO:00091461220.042
cellular response to oxygen containing compoundGO:19017013860.042
positive regulation of biosynthetic processGO:00098913190.041
programmed cell deathGO:00125013920.041
positive regulation of rna metabolic processGO:00512542030.041
apoptotic processGO:00069153810.040
catabolic processGO:00090563510.040
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.039
carbohydrate derivative metabolic processGO:19011353460.039
nucleic acid templated transcriptionGO:00976593790.039
purine ribonucleotide metabolic processGO:00091502270.039
negative regulation of macromolecule metabolic processGO:00106052600.039
transcription from rna polymerase ii promoterGO:00063662520.038
positive regulation of nucleic acid templated transcriptionGO:19035081970.038
ribose phosphate metabolic processGO:00196932350.038
cellular catabolic processGO:00442482950.038
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
regulation of cell proliferationGO:00421273590.037
positive regulation of multicellular organismal processGO:00512403870.037
Rat
purine ribonucleoside metabolic processGO:00461281680.036
purine nucleotide metabolic processGO:00061632290.036
regulation of programmed cell deathGO:00430673410.035
positive regulation of developmental processGO:00510942830.034
Rat
ribonucleoside metabolic processGO:00091191740.034
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
vesicle mediated transportGO:00161921810.033
purine containing compound metabolic processGO:00725212530.032
heterocycle catabolic processGO:00467001670.032
nucleobase containing small molecule metabolic processGO:00550863160.032
single organism intracellular transportGO:19025821660.031
response to peptideGO:19016522920.031
nucleoside monophosphate metabolic processGO:0009123930.031
purine nucleoside catabolic processGO:00061521240.030
regulation of cellular protein metabolic processGO:00322682670.030
organonitrogen compound catabolic processGO:19015651790.030
regulation of molecular functionGO:00650093980.030
regulation of cell differentiationGO:00455953200.029
Rat
neuron projection developmentGO:00311752730.028
Rat
multicellular organism reproductionGO:00325042330.028
regulation of signal transductionGO:00099663180.027
protein transportGO:00150311320.027
response to extracellular stimulusGO:00099913800.027
cellular response to organonitrogen compoundGO:00714171970.026
regulation of phosphorus metabolic processGO:00511743490.026
intracellular signal transductionGO:00355563140.026
negative regulation of nitrogen compound metabolic processGO:00511721610.025
negative regulation of nucleobase containing compound metabolic processGO:00459341530.025
positive regulation of molecular functionGO:00440932300.025
cellular response to nitrogen compoundGO:19016992100.025
positive regulation of cell proliferationGO:00082842490.025
intracellular transportGO:00469071850.025
regulation of protein metabolic processGO:00512462890.025
response to peptide hormoneGO:00434342780.025
ribonucleoside catabolic processGO:00424541260.025
negative regulation of rna metabolic processGO:00512531230.025
negative regulation of cellular metabolic processGO:00313242810.024
negative regulation of metabolic processGO:00098923310.024
reproductive processGO:00224143720.024
nucleotide catabolic processGO:00091661390.023
positive regulation of rna biosynthetic processGO:19026801970.023
ribonucleoside triphosphate catabolic processGO:00092031220.023
glycosyl compound catabolic processGO:19016581260.023
ribonucleoside triphosphate metabolic processGO:00091991410.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.022
negative regulation of cellular biosynthetic processGO:00313271610.022
negative regulation of gene expressionGO:00106291990.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
reproductive system developmentGO:00614581280.022
neurological system processGO:00508772190.022
cellular response to lipidGO:00713962010.022
nucleoside triphosphate metabolic processGO:00091411440.022
organic cyclic compound catabolic processGO:19013611750.022
purine ribonucleoside triphosphate catabolic processGO:00092071220.021
single organism organelle organizationGO:19025891800.021
Rat
cellular component biogenesisGO:00440853680.021
multi organism reproductive processGO:00447032620.021
cellular response to peptideGO:19016531330.021
neuron differentiationGO:00301823680.021
Rat
regulation of phosphate metabolic processGO:00192203490.021
protein localizationGO:00081041910.021
glycosyl compound metabolic processGO:19016571820.021
purine nucleoside triphosphate metabolic processGO:00091441410.021
chromosome segregationGO:000705920.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
purine ribonucleoside catabolic processGO:00461301240.020
regulation of neurogenesisGO:00507672470.020
Rat
negative regulation of rna biosynthetic processGO:19026791180.020
single organism biosynthetic processGO:00447113420.020
cellular protein localizationGO:00346131220.020
regulation of cellular localizationGO:00603412630.019
nucleobase containing compound catabolic processGO:00346551520.019
neuron developmentGO:00486662860.019
Rat
organelle organizationGO:00069962660.019
Rat
homeostatic processGO:00425923310.019
organophosphate metabolic processGO:00196373700.019
growthGO:00400071650.018
aromatic compound catabolic processGO:00194391680.018
regulation of cellular component organizationGO:00511283680.018
Rat
single organism reproductive processGO:00447022970.018
regulation of catalytic activityGO:00507903040.018
positive regulation of cell differentiationGO:00455972170.018
Rat
regulation of cellular catabolic processGO:00313291010.018
nucleoside triphosphate catabolic processGO:00091431230.017
nucleoside metabolic processGO:00091161790.017
cellular component assemblyGO:00226073600.017
negative regulation of transcription dna templatedGO:00458921160.017
organophosphate catabolic processGO:00464341480.017
response to nutrient levelsGO:00316673700.017
positive regulation of phosphorus metabolic processGO:00105622620.017
reproductionGO:00000032450.017
multicellular organismal reproductive processGO:00486092330.017
response to oxidative stressGO:00069791860.017
purine nucleoside monophosphate catabolic processGO:0009128550.017
protein phosphorylationGO:00064683450.017
cellular amino acid metabolic processGO:00065201070.017
purine containing compound catabolic processGO:00725231380.017
brain developmentGO:00074202470.017
Rat
purine ribonucleotide catabolic processGO:00091541360.017
negative regulation of response to stimulusGO:00485851550.017
macromolecule localizationGO:00330362520.016
cytoplasmic transportGO:00164821150.016
organic acid metabolic processGO:00060822920.016
carbohydrate derivative catabolic processGO:19011361470.016
regulation of cellular ketone metabolic processGO:0010565270.016
regulation of cellular amino acid metabolic processGO:000652120.016
macromolecular complex subunit organizationGO:00439333390.016
cellular amine metabolic processGO:0044106380.016
cellular nitrogen compound catabolic processGO:00442701630.016
ribonucleotide catabolic processGO:00092611360.016
regulation of protein modification processGO:00313991940.016
macromolecule catabolic processGO:0009057580.016
Human
cellular response to stressGO:00335542690.016
nucleoside catabolic processGO:00091641260.016
cellular macromolecule localizationGO:00707271220.016
regulation of phosphorylationGO:00423252480.016
regulation of multicellular organismal developmentGO:20000263760.015
Rat
purine nucleoside monophosphate metabolic processGO:0009126840.015
cell projection organizationGO:00300303020.015
Rat
purine ribonucleoside monophosphate metabolic processGO:0009167840.015
regulation of membrane potentialGO:00423911100.015
positive regulation of phosphate metabolic processGO:00459372620.015
regulation of intracellular signal transductionGO:19025312180.015
cellular response to peptide hormone stimulusGO:00713751200.015
response to reactive oxygen speciesGO:00003021200.015
purine nucleotide catabolic processGO:00061951360.015
cellular response to organic cyclic compoundGO:00714072020.015
establishment of protein localizationGO:00451841410.015
axon developmentGO:0061564960.015
membrane organizationGO:0061024940.014
negative regulation of apoptotic processGO:00430661810.014
regulation of system processGO:00440572080.014
central nervous system developmentGO:00074173110.014
Rat
ribonucleoside monophosphate catabolic processGO:0009158550.014
atp catabolic processGO:0006200540.014
single organism catabolic processGO:00447122830.014
response to bacteriumGO:00096172000.014
female pregnancyGO:00075651220.014
gamete generationGO:00072761240.014
peptidyl amino acid modificationGO:00181931260.014
defense responseGO:00069521940.014
purine ribonucleoside monophosphate catabolic processGO:0009169550.014
response to biotic stimulusGO:00096072260.014
cellular component movementGO:00069282480.014
positive regulation of catalytic activityGO:00430851840.014
response to radiationGO:00093141370.014
ribonucleoside monophosphate metabolic processGO:0009161880.014
developmental process involved in reproductionGO:00030061590.014
purine nucleoside metabolic processGO:00422781690.013
development of primary sexual characteristicsGO:00451371070.013
cellular response to external stimulusGO:00714961180.013
positive regulation of protein modification processGO:00314011420.013
atp metabolic processGO:0046034720.013
negative regulation of cell cycle phase transitionGO:190198840.013
positive regulation of cellular amine metabolic processGO:003324030.013
negative regulation of cell deathGO:00605482290.013
positive regulation of transportGO:00510502450.013
agingGO:00075682410.013
response to decreased oxygen levelsGO:00362932370.013
positive regulation of nervous system developmentGO:00519621780.013
Rat
nucleoside monophosphate catabolic processGO:0009125560.013
muscle structure developmentGO:0061061870.013
regulation of cellular amine metabolic processGO:003323880.013
negative regulation of programmed cell deathGO:00430691830.013
positive regulation of neurogenesisGO:00507691650.013
Rat
nitrogen compound transportGO:00717052290.013
immune system processGO:00023762040.013
negative regulation of cell proliferationGO:00082851190.013
reproductive structure developmentGO:00486081280.013
negative regulation of cell differentiationGO:0045596990.013
oxoacid metabolic processGO:00434362900.013
carbohydrate derivative biosynthetic processGO:19011371240.013
amine metabolic processGO:0009308380.013
regulation of anatomical structure morphogenesisGO:00226031410.013
divalent inorganic cation transportGO:00725111340.013
positive regulation of cell developmentGO:00107201760.012
Rat
anatomical structure morphogenesisGO:00096532980.012
regulation of cell projection organizationGO:00313441750.012
Rat
response to oxygen levelsGO:00704822650.012
proteolysisGO:00065081750.012
Human
embryonic pattern specificationGO:000988010.012
negative regulation of multicellular organismal processGO:00512412030.012
single organism cellular localizationGO:19025801020.012
nucleoside phosphate catabolic processGO:19012921400.012
response to growth factorGO:00708481890.012
lipid storageGO:001991510.012
cardiac chamber developmentGO:000320510.012
response to cytokineGO:00340972150.012
regulation of kinase activityGO:00435491170.012
protein complex subunit organizationGO:00718223020.012
multi multicellular organism processGO:00447061380.012
positive regulation of signalingGO:00230562700.011
immune responseGO:00069551040.011
negative regulation of neurogenesisGO:0050768780.011
positive regulation of phosphorylationGO:00423271770.011
response to nutrientGO:00075842480.011
regulation of nucleotide metabolic processGO:00061401170.011
organophosphate biosynthetic processGO:00904071430.011
multicellular organism growthGO:003526410.011
positive regulation of catabolic processGO:0009896780.011
regulation of growthGO:00400081050.011
lipid metabolic processGO:00066292830.011
positive regulation of response to stimulusGO:00485842850.011
response to estradiolGO:00323551640.011
cytokine biosynthetic processGO:004208930.011
cellular ketone metabolic processGO:0042180510.011
positive regulation of signal transductionGO:00099671750.011
response to metal ionGO:00100382530.011
neuromuscular processGO:005090520.011
blood circulationGO:00080151830.011
biological adhesionGO:00226101100.011
negative regulation of biosynthetic processGO:00098901680.011
calcium ion transportGO:00068161310.011
negative regulation of cellular component organizationGO:0051129830.011
gland developmentGO:00487321550.011
muscle system processGO:00030121150.011
response to mechanical stimulusGO:00096121340.011
ras protein signal transductionGO:0007265290.011
negative regulation of transportGO:00510511360.011
negative regulation of innate immune responseGO:004582440.011
regulation of nervous system developmentGO:00519602640.011
Rat
protein complex assemblyGO:00064612630.011
positive regulation of cellular component organizationGO:00511302000.011
Rat
response to insulinGO:00328681330.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.010
positive regulation of protein metabolic processGO:00512471780.010
regulation of cytokine biosynthetic processGO:004203530.010
secretionGO:00469033070.010
negative regulation of developmental processGO:00510931250.010
positive regulation of apoptotic processGO:00430651540.010
response to hydrogen peroxideGO:0042542890.010
male gamete generationGO:0048232990.010
regulation of neuron differentiationGO:00456642080.010
Rat
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
response to corticosteroidGO:00319602350.010
cation transportGO:00068123820.010
jak stat cascadeGO:0007259260.010
negative regulation of molecular functionGO:00440921330.010
cell growthGO:00160491040.010
cofactor metabolic processGO:0051186950.010
chemosensory behaviorGO:000763520.010
cell cycleGO:00070491010.010
double strand break repairGO:000630210.010
neuron deathGO:00709971270.010
cellular response to growth factor stimulusGO:00713631620.010
lipid biosynthetic processGO:00086101280.010
sexual reproductionGO:00199531480.010
reactive oxygen species biosynthetic processGO:190340980.010

Keap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
central nervous system diseaseDOID:33100.013
musculoskeletal system diseaseDOID:1700.012