Rattus norvegicus

0 known processes

Slc4a4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

(Aliases: Nbc4,HHNMC,Nbc1,NBC2,KNBC,PNBC,SLC4A5,HNBC1)

Slc4a4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161921810.233
rna metabolic processGO:00160704060.227
cellular response to oxygen containing compoundGO:19017013860.212
regulation of rna biosynthetic processGO:20011413810.202
cell cell signalingGO:00072673350.168
neural crest cell differentiationGO:001403320.165
negative regulation of gene expressionGO:00106291990.163
neuron differentiationGO:00301823680.156
regulation of multicellular organismal developmentGO:20000263760.150
neuron projection morphogenesisGO:00488121220.149
response to oxygen levelsGO:00704822650.143
response to acid chemicalGO:00011012220.136
protein phosphorylationGO:00064683450.135
cellular response to endogenous stimulusGO:00714953770.129
regulation of cell developmentGO:00602842630.126
cellular response to lipidGO:00713962010.125
response to estradiolGO:00323551640.121
nitrogen compound transportGO:00717052290.121
negative regulation of metabolic processGO:00098923310.120
transcription dna templatedGO:00063513770.119
carboxylic acid metabolic processGO:00197522890.118
anatomical structure morphogenesisGO:00096532980.115
transmembrane transportGO:00550854120.115
Human Rat
response to nutrient levelsGO:00316673700.114
cation transportGO:00068123820.114
Human
response to external biotic stimulusGO:00432072210.112
regulation of transcription from rna polymerase ii promoterGO:00063572340.110
cellular component movementGO:00069282480.109
reproductive processGO:00224143720.106
negative regulation of cellular metabolic processGO:00313242810.104
regulation of transcription dna templatedGO:00063553740.102
cellular response to stressGO:00335542690.101
cellular response to organic cyclic compoundGO:00714072020.101
response to other organismGO:00517072200.101
cellular response to nitrogen compoundGO:19016992100.098
single organism reproductive processGO:00447022970.098
positive regulation of signalingGO:00230562700.098
neuron developmentGO:00486662860.097
cellular response to organonitrogen compoundGO:00714171970.096
locomotionGO:00400112370.095
central nervous system developmentGO:00074173110.094
response to campGO:0051591910.093
positive regulation of cell communicationGO:00106472710.092
organic acid metabolic processGO:00060822920.092
protein complex assemblyGO:00064612630.091
positive regulation of response to stimulusGO:00485842850.090
cation transmembrane transportGO:00986552630.089
Human
regulation of cellular component organizationGO:00511283680.087
positive regulation of signal transductionGO:00099671750.085
positive regulation of nucleobase containing compound metabolic processGO:00459353190.083
positive regulation of nucleic acid templated transcriptionGO:19035081970.083
cellular response to hormone stimulusGO:00328702470.082
regulation of cell differentiationGO:00455953200.081
nucleic acid templated transcriptionGO:00976593790.081
protein oligomerizationGO:00512591910.081
homeostatic processGO:00425923310.081
negative regulation of multicellular organismal processGO:00512412030.080
response to hypoxiaGO:00016662310.080
regulation of cellular component movementGO:00512701500.078
regulation of neurogenesisGO:00507672470.077
positive regulation of cellular biosynthetic processGO:00313282950.077
response to extracellular stimulusGO:00099913800.076
intracellular signal transductionGO:00355563140.075
localization of cellGO:00516742020.075
positive regulation of biosynthetic processGO:00098913190.074
organic substance catabolic processGO:19015753160.074
regulation of cellular protein metabolic processGO:00322682670.074
macromolecular complex assemblyGO:00650032730.073
regulation of nervous system developmentGO:00519602640.072
cellular chemical homeostasisGO:00550822470.072
response to estrogenGO:00436272320.071
regulation of protein phosphorylationGO:00019321830.070
negative regulation of macromolecule metabolic processGO:00106052600.070
transcription from rna polymerase ii promoterGO:00063662520.070
negative regulation of macromolecule biosynthetic processGO:00105581480.069
regulation of phosphorus metabolic processGO:00511743490.069
regulation of cell motilityGO:20001451310.068
response to nutrientGO:00075842480.067
reproductionGO:00000032450.066
neuron projection developmentGO:00311752730.065
multicellular organism reproductionGO:00325042330.065
cell morphogenesisGO:00009021420.065
cellular component biogenesisGO:00440853680.064
regulation of protein metabolic processGO:00512462890.064
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.063
chemical homeostasisGO:00488782920.062
cellular component assemblyGO:00226073600.062
ion transmembrane transportGO:00342203650.061
Human Rat
regulation of cell projection organizationGO:00313441750.061
response to alkaloidGO:00432791320.061
learning or memoryGO:0007611900.060
positive regulation of developmental processGO:00510942830.060
multi organism reproductive processGO:00447032620.059
cellular component morphogenesisGO:00329891550.058
cellular homeostasisGO:00197252520.058
oxoacid metabolic processGO:00434362900.057
head developmentGO:00603222470.057
macromolecular complex subunit organizationGO:00439333390.057
neural crest cell developmentGO:001403220.056
response to decreased oxygen levelsGO:00362932370.056
response to peptideGO:19016522920.056
inorganic ion transmembrane transportGO:00986602290.055
Human
brain developmentGO:00074202470.055
response to carbohydrateGO:00097431830.055
rna biosynthetic processGO:00327743800.055
positive regulation of transcription dna templatedGO:00458931970.055
negative regulation of biosynthetic processGO:00098901680.054
positive regulation of macromolecule biosynthetic processGO:00105572470.054
neuron neuron synaptic transmissionGO:0007270600.053
negative regulation of protein metabolic processGO:00512481140.052
cardiovascular system developmentGO:00723581340.052
positive regulation of multicellular organismal processGO:00512403870.052
cell motilityGO:00488702020.052
anterior posterior pattern specificationGO:000995210.052
axis specificationGO:000979840.051
tissue developmentGO:00098882520.051
negative regulation of developmental processGO:00510931250.051
regulation of phosphate metabolic processGO:00192203490.051
circulatory system processGO:00030131830.051
response to insulinGO:00328681330.050
positive regulation of rna biosynthetic processGO:19026801970.050
response to ethanolGO:00454711620.050
negative regulation of cellular protein metabolic processGO:00322691060.050
response to purine containing compoundGO:00140741260.049
cell migrationGO:00164771970.049
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.049
positive regulation of molecular functionGO:00440932300.048
response to interleukin 2GO:007066910.048
cell projection morphogenesisGO:00488581230.047
response to ammonium ionGO:0060359710.047
cell morphogenesis involved in differentiationGO:00009041190.047
positive regulation of nitrogen compound metabolic processGO:00511733340.047
regulation of rna metabolic processGO:00512523910.046
positive regulation of phosphate metabolic processGO:00459372620.046
secretionGO:00469033070.046
response to inorganic substanceGO:00100353770.045
regulation of molecular functionGO:00650093980.045
protein complex biogenesisGO:00702712630.044
regulation of phosphorylationGO:00423252480.044
amide transportGO:00428861050.043
protein complex subunit organizationGO:00718223020.043
agingGO:00075682410.043
regulation of nucleic acid templated transcriptionGO:19035063800.043
negative regulation of nitrogen compound metabolic processGO:00511721610.043
cellular catabolic processGO:00442482950.043
response to peptide hormoneGO:00434342780.043
regulation of neuron differentiationGO:00456642080.041
regulation of cell proliferationGO:00421273590.041
regulation of cell migrationGO:00303341280.040
regulation of ion transportGO:00432692450.040
programmed cell deathGO:00125013920.040
regulation of anatomical structure morphogenesisGO:00226031410.040
biological adhesionGO:00226101100.040
regulation of intracellular signal transductionGO:19025312180.040
cellular carbohydrate metabolic processGO:0044262720.040
response to biotic stimulusGO:00096072260.040
response to cytokineGO:00340972150.039
cellular response to acid chemicalGO:0071229750.039
positive regulation of nervous system developmentGO:00519621780.039
anion transmembrane transportGO:0098656770.039
leukocyte activationGO:0045321760.038
cellular response to cytokine stimulusGO:00713451270.038
positive regulation of cell migrationGO:0030335960.038
synaptic transmissionGO:00072682350.038
multicellular organismal reproductive processGO:00486092330.037
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.037
cellular amino acid metabolic processGO:00065201070.037
single organism behaviorGO:00447081300.037
multi multicellular organism processGO:00447061380.037
rhythmic processGO:00485111560.037
positive regulation of protein metabolic processGO:00512471780.037
intracellular transportGO:00469071850.036
cellular amine metabolic processGO:0044106380.036
regulation of locomotionGO:00400121480.036
amine metabolic processGO:0009308380.035
metal ion transportGO:00300012890.035
Human
response to glucocorticoidGO:00513842230.035
locomotory exploration behaviorGO:003564110.035
positive regulation of cell developmentGO:00107201760.035
regulation of programmed cell deathGO:00430673410.035
negative regulation of organ growthGO:004662130.034
cell adhesionGO:00071551100.034
wound healingGO:00420601220.034
negative regulation of cardiac muscle tissue developmentGO:005502630.034
ion homeostasisGO:00508012120.034
negative regulation of cell differentiationGO:0045596990.033
divalent inorganic cation transportGO:00725111340.033
regulation of carbohydrate metabolic processGO:0006109410.033
response to monosaccharideGO:00342841590.032
synapse organizationGO:0050808460.032
negative regulation of cellular biosynthetic processGO:00313271610.032
positive regulation of cellular component organizationGO:00511302000.031
positive regulation of gene expressionGO:00106282440.031
circadian rhythmGO:0007623880.031
enzyme linked receptor protein signaling pathwayGO:00071671160.031
positive regulation of transportGO:00510502450.031
protein homooligomerizationGO:0051260910.031
regulation of catalytic activityGO:00507903040.031
hormone transportGO:00099141210.031
response to molecule of bacterial originGO:00022371940.030
monocarboxylic acid metabolic processGO:00327871520.030
regulation of translationGO:0006417270.030
cellular ketone metabolic processGO:0042180510.030
insulin secretionGO:0030073690.030
catabolic processGO:00090563510.030
cell cycleGO:00070491010.030
response to metal ionGO:00100382530.030
positive regulation of catalytic activityGO:00430851840.030
regulation of signal transductionGO:00099663180.030
synaptic transmission gabaergicGO:0051932220.030
calcium ion transportGO:00068161310.029
cellular response to growth factor stimulusGO:00713631620.029
negative regulation of apoptotic processGO:00430661810.029
organ morphogenesisGO:0009887750.029
lipid metabolic processGO:00066292830.029
establishment of vesicle localizationGO:0051650310.029
positive regulation of cellular protein metabolic processGO:00322701670.029
regulation of cellular catabolic processGO:00313291010.029
behaviorGO:00076102050.028
negative regulation of cell developmentGO:0010721820.028
female pregnancyGO:00075651220.028
vasculogenesisGO:000157030.028
negative regulation of osteoblast differentiationGO:004566820.028
regulation of catabolic processGO:00098941130.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.028
macromolecule localizationGO:00330362520.027
response to toxic substanceGO:00096361330.027
regenerationGO:00310991630.027
skeletal system developmentGO:0001501410.027
carboxylic acid transportGO:00469421150.027
positive regulation of phosphorylationGO:00423271770.027
muscle tissue developmentGO:0060537580.027
positive regulation of cell differentiationGO:00455972170.027
regulation of response to stressGO:00801341260.027
response to woundingGO:00096112540.026
regulation of synaptic growth at neuromuscular junctionGO:000858210.026
regulation of protein modification processGO:00313991940.026
response to growth factorGO:00708481890.026
regulation of smooth muscle cell proliferationGO:0048660750.026
negative regulation of nervous system developmentGO:0051961790.026
cellular response to peptideGO:19016531330.026
response to ketoneGO:19016541820.026
cognitionGO:0050890920.026
cell projection organizationGO:00300303020.026
positive regulation of phosphorus metabolic processGO:00105622620.026
response to glucoseGO:00097491360.026
regulation of cellular localizationGO:00603412630.026
translationGO:0006412350.025
epithelium developmentGO:0060429960.025
response to mechanical stimulusGO:00096121340.025
positive regulation of neurogenesisGO:00507691650.025
negative regulation of heart growthGO:006111730.025
single organism carbohydrate metabolic processGO:00447231180.025
organic anion transportGO:00157111320.025
Human
single organism biosynthetic processGO:00447113420.025
cellular lipid metabolic processGO:00442552080.025
negative regulation of nucleic acid templated transcriptionGO:19035071170.025
organophosphate metabolic processGO:00196373700.025
negative regulation of cell proliferationGO:00082851190.025
response to organophosphorusGO:00466831020.025
negative regulation of cardiac muscle cell proliferationGO:006004420.025
inorganic cation transmembrane transportGO:00986622020.025
Human
apoptotic processGO:00069153810.025
blood circulationGO:00080151830.024
anion transportGO:00068201780.024
Human Rat
regulation of cellular ketone metabolic processGO:0010565270.024
establishment of tissue polarityGO:000716420.024
neurological system processGO:00508772190.024
cellular macromolecular complex assemblyGO:0034622580.024
regulation of cellular amino acid metabolic processGO:000652120.024
regulation of synapse maturationGO:009012820.024
regulation of cellular amine metabolic processGO:003323880.024
oxidation reduction processGO:00551143040.023
peptide hormone secretionGO:0030072840.023
regulation of canonical wnt signaling pathwayGO:006082840.023
positive regulation of response to woundingGO:1903036340.023
sexual reproductionGO:00199531480.023
peptide transportGO:0015833970.023
positive regulation of mesenchymal cell proliferationGO:000205340.023
positive regulation of protein phosphorylationGO:00019341350.023
small gtpase mediated signal transductionGO:0007264360.023
regulation of secretion by cellGO:19035302080.022
response to corticosteroidGO:00319602350.022
divalent metal ion transportGO:00708381320.022
regulation of mesenchymal cell proliferationGO:001046440.022
response to hexoseGO:00097461440.022
hormone secretionGO:00468791150.022
positive regulation of ion transportGO:0043270940.022
negative regulation of signalingGO:00230571570.022
calcium ion homeostasisGO:00550741620.022
cellular calcium ion homeostasisGO:00068741600.022
striated muscle tissue developmentGO:0014706580.021
regulation of metal ion transportGO:00109591180.021
single organism cell adhesionGO:0098602460.021
mapk cascadeGO:00001651400.021
peptide secretionGO:0002790860.021
single organism intracellular transportGO:19025821660.021
insulin like growth factor receptor signaling pathwayGO:004800930.021
positive regulation of catabolic processGO:0009896780.021
regulation of secretionGO:00510462240.021
positive regulation of rna metabolic processGO:00512542030.021
regulation of dendrite developmentGO:0050773590.021
response to vitaminGO:00332731310.021
embryonic skeletal system developmentGO:004870630.020
dendrite morphogenesisGO:0048813430.020
cell part morphogenesisGO:00329901230.020
negative regulation of rna metabolic processGO:00512531230.020
carbohydrate derivative metabolic processGO:19011353460.020
regulation of hormone levelsGO:00108171870.020
cellular response to cgmpGO:007132120.020
positive regulation of neuron differentiationGO:00456661260.020
regulation of cell adhesionGO:0030155520.020
response to radiationGO:00093141370.020
cell type specific apoptotic processGO:00972851340.020
organic cyclic compound catabolic processGO:19013611750.020
regulation of membrane potentialGO:00423911100.020
regulation of cell cycleGO:0051726730.020
protein localizationGO:00081041910.019
organelle localizationGO:0051640550.019
mesenchymal cell proliferationGO:001046340.019
cellular ion homeostasisGO:00068731840.019
regulation of insulin secretionGO:0050796650.019
liver developmentGO:0001889900.019
negative regulation of transportGO:00510511360.019
multicellular organismal signalingGO:0035637440.019
amino acid transportGO:0006865700.019
regulation of neuron projection developmentGO:00109751610.019
transmission of nerve impulseGO:0019226420.019
regulation of transferase activityGO:00513381230.019
regulation of blood vessel sizeGO:0050880890.019
cellular response to vitamin eGO:007130630.019
neurotransmitter transportGO:0006836420.019
organ regenerationGO:00311001010.019
negative regulation of translational initiationGO:004594750.019
positive regulation of protein modification processGO:00314011420.019
cellular protein complex assemblyGO:0043623440.019
regulation of hydrolase activityGO:00513361430.019
positive regulation of intracellular signal transductionGO:19025331380.018
muscle cell proliferationGO:0033002840.018
regulation of growthGO:00400081050.018
heart morphogenesisGO:000300730.018
fatty acid metabolic processGO:0006631990.018
regulation of synaptic transmissionGO:00508041410.018
embryo developmentGO:0009790490.018
regulation of peptide transportGO:0090087870.018
cerebellar granule cell precursor proliferationGO:002193010.018
germ cell migrationGO:000835410.018
action potentialGO:0001508540.018
tissue regenerationGO:0042246360.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
organic acid transportGO:00158491160.018
regulation of response to woundingGO:1903034690.017
single organism catabolic processGO:00447122830.017
protein heterooligomerizationGO:0051291890.017
developmental process involved in reproductionGO:00030061590.017
cellular protein localizationGO:00346131220.017
signal releaseGO:00230611450.017
growthGO:00400071650.017
exploration behaviorGO:003564010.017
ribose phosphate metabolic processGO:00196932350.017
gastrulationGO:000736920.017
posttranscriptional regulation of gene expressionGO:0010608370.017
memoryGO:0007613540.017
positive regulation of cell proliferationGO:00082842490.017
maintenance of locationGO:0051235170.017
defense responseGO:00069521940.017
circulatory system developmentGO:00723591340.017
reproductive structure developmentGO:00486081280.017
osteoblast differentiationGO:0001649260.017
cellular response to peptide hormone stimulusGO:00713751200.017
negative regulation of neurogenesisGO:0050768780.017
dephosphorylationGO:0016311980.017
negative regulation of calcium ion transport into cytosolGO:001052340.016
carbohydrate metabolic processGO:00059751300.016
regulation of cellular carbohydrate metabolic processGO:0010675390.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
gland developmentGO:00487321550.016
endocytosisGO:0006897840.016
lipid biosynthetic processGO:00086101280.016
regulation of anatomical structure sizeGO:00900661350.016
organelle organizationGO:00069962660.016
cytoplasmic transportGO:00164821150.016
metal ion homeostasisGO:00550651860.016
response to lipopolysaccharideGO:00324961910.016
taxisGO:0042330670.016
cellular hyperosmotic responseGO:007147440.016
microtubule organizing center organizationGO:003102310.016
organic hydroxy compound metabolic processGO:19016151150.016
axonogenesisGO:0007409710.016
regulation of establishment of planar polarityGO:009017520.016
blood vessel developmentGO:0001568690.016
regulation of homeostatic processGO:00328441010.015
amino acid transmembrane transportGO:0003333330.015
hexose metabolic processGO:0019318580.015
cellular response to extracellular stimulusGO:0031668730.015
positive regulation of locomotionGO:00400171020.015
smooth muscle cell proliferationGO:0048659770.015
macromolecule catabolic processGO:0009057580.015
response to retinoic acidGO:0032526630.015
organ formationGO:004864530.015
response to bacteriumGO:00096172000.015
response to transition metal nanoparticleGO:19902671220.015
purine nucleotide metabolic processGO:00061632290.015
response to nicotineGO:0035094510.015
regulation of gamma aminobutyric acid secretionGO:001405260.014
regulation of peptide secretionGO:0002791820.014
negative regulation of catalytic activityGO:00430861030.014
neurotransmitter uptakeGO:000150430.014
monocarboxylic acid transportGO:0015718520.014
negative regulation of cell deathGO:00605482290.014
divalent inorganic cation homeostasisGO:00725071650.014
positive regulation of cell adhesionGO:0045785300.014
regulation of hormone secretionGO:00468831060.014
gamete generationGO:00072761240.014
generation of precursor metabolites and energyGO:0006091620.014
ras protein signal transductionGO:0007265290.014
cellular response to interleukin 2GO:007135210.014
urogenital system developmentGO:0001655780.014
negative regulation of rna biosynthetic processGO:19026791180.014
single organism cellular localizationGO:19025801020.014
heterocycle catabolic processGO:00467001670.014
cellular cation homeostasisGO:00300031800.014
regulation of cellular response to stressGO:0080135490.014
single organism organelle organizationGO:19025891800.014
positive regulation of cell deathGO:00109421840.014
ossificationGO:0001503700.014
cellular response to abiotic stimulusGO:0071214850.014
cellular macromolecule localizationGO:00707271220.014
heart developmentGO:0007507720.014
serotonin metabolic processGO:004242830.014
regulation of vesicle mediated transportGO:0060627810.014
cytosolic calcium ion homeostasisGO:00514801400.014
eye morphogenesisGO:004859240.014
lipid modificationGO:0030258520.014
membrane organizationGO:0061024940.014
developmental inductionGO:003112820.014
cellular metal ion homeostasisGO:00068751720.014
cellular response to alcoholGO:0097306870.014
positive regulation of lipid catabolic processGO:005099640.014
synaptic growth at neuromuscular junctionGO:005112410.014
positive regulation of synaptic transmissionGO:0050806620.013
positive regulation of cellular amine metabolic processGO:003324030.013
organic hydroxy compound transportGO:0015850770.013
developmental growthGO:00485891000.013
nucleobase containing compound catabolic processGO:00346551520.013
lens fiber cell differentiationGO:007030630.013
positive regulation of neuron projection developmentGO:0010976990.013
regulation of body fluid levelsGO:0050878900.013
multicellular organismal homeostasisGO:0048871490.013
nucleotide metabolic processGO:00091172790.013
activation of mapkkk activityGO:000018510.013
positive regulation of secretionGO:00510471400.013
immune responseGO:00069551040.013
nucleoside phosphate metabolic processGO:00067532830.013
regulation of transporter activityGO:0032409500.013
purine ribonucleoside metabolic processGO:00461281680.013
positive regulation of synapse maturationGO:009012920.013
regulation of neurotransmitter levelsGO:0001505420.013
regulation of calcium ion transportGO:0051924770.013
ribonucleotide catabolic processGO:00092611360.012
negative regulation of cell communicationGO:00106481580.012
cation homeostasisGO:00550801950.012
glucose homeostasisGO:0042593750.012
actin filament based processGO:0030029860.012
molting cycle processGO:002240420.012
regulation of transmembrane transporter activityGO:0022898490.012
wnt signaling pathway involved in dorsal ventral axis specificationGO:004433210.012
connective tissue developmentGO:0061448330.012
pyruvate metabolic processGO:0006090270.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
male mating behaviorGO:006017930.012
macrophage chemotaxisGO:004824620.012
appendage morphogenesisGO:003510740.012
regulation of transmembrane transportGO:00347621220.012
single organismal cell cell adhesionGO:0016337420.012
regulation of cell growthGO:0001558850.012
reproductive system developmentGO:00614581280.012
bmp signaling pathwayGO:003050940.012
ncrna processingGO:003447030.012
muscle organ developmentGO:0007517500.012
positive regulation of gamma aminobutyric acid secretionGO:001405440.012
negative regulation of molecular functionGO:00440921330.012
neuronal action potentialGO:0019228350.012
regulation of cell morphogenesisGO:0022604770.012
negative regulation of response to stimulusGO:00485851550.012
coenzyme metabolic processGO:0006732860.012
nucleotide catabolic processGO:00091661390.012
mechanoreceptor differentiationGO:004249020.012
synaptic vesicle transportGO:0048489230.012
negative regulation of programmed cell deathGO:00430691830.012
regulation of sodium ion transmembrane transporter activityGO:200064940.012

Slc4a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
disease of metabolismDOID:001466700.016
disease of cellular proliferationDOID:1456600.013