Rattus norvegicus

25 known processes

Cldn16

claudin 16

(Aliases: Pcln1)

Cldn16 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123820.300
homeostatic processGO:00425923310.226
reproductive processGO:00224143720.177
cellular divalent inorganic cation homeostasisGO:00725031620.172
tissue developmentGO:00098882520.171
regulation of phosphorus metabolic processGO:00511743490.159
cation transmembrane transportGO:00986552630.145
regulation of molecular functionGO:00650093980.140
cellular response to lipidGO:00713962010.134
oxoacid metabolic processGO:00434362900.131
response to inorganic substanceGO:00100353770.122
negative regulation of cell deathGO:00605482290.114
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.112
inorganic ion transmembrane transportGO:00986602290.109
response to ketoneGO:19016541820.109
ion transmembrane transportGO:00342203650.106
divalent inorganic cation homeostasisGO:00725071650.102
positive regulation of cell communicationGO:00106472710.101
negative regulation of transportGO:00510511360.089
g protein coupled receptor signaling pathwayGO:00071862420.088
regulation of transmembrane transportGO:00347621220.083
positive regulation of cell proliferationGO:00082842490.082
transcription from rna polymerase ii promoterGO:00063662520.080
blood circulationGO:00080151830.079
metal ion transportGO:00300012890.078
positive regulation of cellular biosynthetic processGO:00313282950.078
circulatory system processGO:00030131830.077
regulation of phosphate metabolic processGO:00192203490.072
anatomical structure morphogenesisGO:00096532980.071
cation homeostasisGO:00550801950.070
nitrogen compound transportGO:00717052290.070
cell motilityGO:00488702020.068
inorganic cation transmembrane transportGO:00986622020.068
response to estrogenGO:00436272320.068
anion transmembrane transportGO:0098656770.067
organic acid metabolic processGO:00060822920.065
intracellular signal transductionGO:00355563140.064
response to decreased oxygen levelsGO:00362932370.064
regulation of catalytic activityGO:00507903040.064
programmed cell deathGO:00125013920.062
cellular response to alcoholGO:0097306870.062
cellular component assemblyGO:00226073600.062
positive regulation of biosynthetic processGO:00098913190.061
single organism reproductive processGO:00447022970.060
response to oxygen levelsGO:00704822650.060
tube developmentGO:0035295890.058
positive regulation of developmental processGO:00510942830.058
regulation of cellular protein metabolic processGO:00322682670.058
carboxylic acid metabolic processGO:00197522890.057
positive regulation of gene expressionGO:00106282440.056
regulation of apoptotic processGO:00429813350.055
calcium mediated signalingGO:0019722230.055
positive regulation of rna metabolic processGO:00512542030.055
head developmentGO:00603222470.055
response to ethanolGO:00454711620.054
positive regulation of signalingGO:00230562700.053
regulation of nucleic acid templated transcriptionGO:19035063800.052
regulation of metal ion transportGO:00109591180.052
defense responseGO:00069521940.051
negative regulation of nitrogen compound metabolic processGO:00511721610.050
response to cytokineGO:00340972150.049
response to hypoxiaGO:00016662310.048
single organism biosynthetic processGO:00447113420.048
regulation of cellular component organizationGO:00511283680.048
response to biotic stimulusGO:00096072260.048
positive regulation of transcription dna templatedGO:00458931970.048
cellular response to nitrogen compoundGO:19016992100.047
dopamine secretionGO:0014046150.047
regulation of locomotionGO:00400121480.047
sensory organ developmentGO:0007423740.046
regulation of homeostatic processGO:00328441010.045
vesicle mediated transportGO:00161921810.045
positive regulation of cell deathGO:00109421840.045
positive regulation of phosphorus metabolic processGO:00105622620.045
circadian rhythmGO:0007623880.045
protein complex subunit organizationGO:00718223020.044
neurological system processGO:00508772190.044
cellular ion homeostasisGO:00068731840.044
regulation of multicellular organismal developmentGO:20000263760.044
positive regulation of nitrogen compound metabolic processGO:00511733340.043
chemical homeostasisGO:00488782920.042
regulation of ion transportGO:00432692450.042
response to extracellular stimulusGO:00099913800.042
cell morphogenesis involved in differentiationGO:00009041190.042
positive regulation of multicellular organismal processGO:00512403870.042
secretion by cellGO:00329402480.042
regulation of cell differentiationGO:00455953200.041
protein complex biogenesisGO:00702712630.041
response to corticosteroidGO:00319602350.041
inflammatory responseGO:00069541500.040
metal ion homeostasisGO:00550651860.040
positive regulation of rna biosynthetic processGO:19026801970.040
transmembrane transportGO:00550854120.039
calcium ion homeostasisGO:00550741620.039
positive regulation of molecular functionGO:00440932300.038
positive regulation of macromolecule biosynthetic processGO:00105572470.038
response to nutrient levelsGO:00316673700.038
multi organism reproductive processGO:00447032620.037
rna metabolic processGO:00160704060.037
agingGO:00075682410.037
regulation of rna biosynthetic processGO:20011413810.037
macromolecular complex subunit organizationGO:00439333390.037
divalent inorganic cation transportGO:00725111340.036
negative regulation of biosynthetic processGO:00098901680.036
negative regulation of gene expressionGO:00106291990.036
regulation of transcription dna templatedGO:00063553740.036
cellular homeostasisGO:00197252520.036
regulation of protein metabolic processGO:00512462890.035
halogenated hydrocarbon metabolic processGO:004219740.035
epithelium developmentGO:0060429960.035
transcription dna templatedGO:00063513770.034
lipid metabolic processGO:00066292830.034
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
cellular response to organic cyclic compoundGO:00714072020.034
positive regulation of cell differentiationGO:00455972170.034
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.034
ossificationGO:0001503700.034
regulation of protein modification processGO:00313991940.033
negative regulation of macromolecule metabolic processGO:00106052600.033
regulation of programmed cell deathGO:00430673410.033
regulation of ion transmembrane transportGO:00347651210.032
macromolecular complex assemblyGO:00650032730.032
regulation of phosphorylationGO:00423252480.032
positive regulation of apoptotic processGO:00430651540.031
ion homeostasisGO:00508012120.031
dopamine transportGO:0015872180.031
cellular component biogenesisGO:00440853680.031
amine metabolic processGO:0009308380.031
positive regulation of programmed cell deathGO:00430681570.031
response to acid chemicalGO:00011012220.031
sodium ion transportGO:0006814820.031
cellular amine metabolic processGO:0044106380.030
regulation of rna metabolic processGO:00512523910.030
positive regulation of synaptic transmissionGO:0050806620.030
cardiovascular system developmentGO:00723581340.030
regulation of smooth muscle cell proliferationGO:0048660750.030
catecholamine secretionGO:0050432330.029
rna biosynthetic processGO:00327743800.029
rhythmic processGO:00485111560.029
regulation of hormone levelsGO:00108171870.029
localization of cellGO:00516742020.029
oligopeptide transportGO:000685740.028
organic hydroxy compound transportGO:0015850770.028
cellular response to hormone stimulusGO:00328702470.028
response to ammonium ionGO:0060359710.028
response to amineGO:0014075460.028
organ formationGO:004864530.027
central nervous system developmentGO:00074173110.027
negative regulation of rna biosynthetic processGO:19026791180.027
positive regulation of cellular component organizationGO:00511302000.027
cellular response to oxygen levelsGO:0071453600.026
protein complex assemblyGO:00064612630.026
cytosolic calcium ion homeostasisGO:00514801400.026
regulation of cellular amine metabolic processGO:003323880.026
organophosphate biosynthetic processGO:00904071430.026
cellular cation homeostasisGO:00300031800.026
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.026
response to other organismGO:00517072200.026
catecholamine transportGO:0051937370.026
regulation of cellular localizationGO:00603412630.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
regulation of membrane potentialGO:00423911100.025
ribonucleotide metabolic processGO:00092592310.025
cellular ketone metabolic processGO:0042180510.024
neuron projection developmentGO:00311752730.024
cellular response to organonitrogen compoundGO:00714171970.024
cellular amino acid metabolic processGO:00065201070.024
organophosphate metabolic processGO:00196373700.024
cellular response to stressGO:00335542690.024
organic cyclic compound catabolic processGO:19013611750.024
response to lipopolysaccharideGO:00324961910.024
response to monosaccharideGO:00342841590.024
nucleic acid templated transcriptionGO:00976593790.024
cellular chemical homeostasisGO:00550822470.023
cellular response to oxygen containing compoundGO:19017013860.023
response to estradiolGO:00323551640.023
response to metal ionGO:00100382530.022
female pregnancyGO:00075651220.022
positive regulation of intracellular signal transductionGO:19025331380.022
regulation of blood circulationGO:19035221100.022
monovalent inorganic cation transportGO:00156721720.022
multi multicellular organism processGO:00447061380.022
response to molecule of bacterial originGO:00022371940.022
neuron differentiationGO:00301823680.022
regulation of transferase activityGO:00513381230.022
cellular metal ion homeostasisGO:00068751720.022
positive regulation of protein phosphorylationGO:00019341350.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
response to external biotic stimulusGO:00432072210.021
positive regulation of nervous system developmentGO:00519621780.021
regulation of cellular amino acid metabolic processGO:000652120.021
response to glucocorticoidGO:00513842230.021
positive regulation of cytosolic calcium ion concentrationGO:00072041220.021
positive regulation of phosphorylationGO:00423271770.020
response to bacteriumGO:00096172000.020
regulation of cellular ketone metabolic processGO:0010565270.020
negative regulation of programmed cell deathGO:00430691830.020
divalent metal ion transportGO:00708381320.020
negative regulation of apoptotic processGO:00430661810.020
positive regulation of organelle organizationGO:0010638480.020
sodium ion transmembrane transportGO:0035725670.020
cellular response to acid chemicalGO:0071229750.019
regulation of catecholamine secretionGO:0050433320.019
brain developmentGO:00074202470.019
positive regulation of growthGO:0045927550.019
antibiotic transportGO:004289120.019
response to nutrientGO:00075842480.019
response to histamineGO:003477630.019
vasculature developmentGO:0001944700.019
cellular response to drugGO:0035690300.019
sexual reproductionGO:00199531480.019
regulation of secretion by cellGO:19035302080.019
positive regulation of mapk cascadeGO:0043410920.018
response to woundingGO:00096112540.018
epithelial cell differentiationGO:0030855710.018
carbohydrate derivative biosynthetic processGO:19011371240.018
locomotionGO:00400112370.018
membrane organizationGO:0061024940.018
positive regulation of transportGO:00510502450.018
phospholipid metabolic processGO:0006644610.018
regulation of vasculature developmentGO:1901342440.018
negative regulation of transcription dna templatedGO:00458921160.018
regulation of signal transductionGO:00099663180.018
cellular component movementGO:00069282480.018
purine containing compound metabolic processGO:00725212530.017
apoptotic processGO:00069153810.017
negative regulation of cellular biosynthetic processGO:00313271610.017
protein phosphorylationGO:00064683450.017
negative regulation of multicellular organismal processGO:00512412030.017
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
camp biosynthetic processGO:0006171470.017
regulation of calcium ion transportGO:0051924770.017
regulation of peptide transportGO:0090087870.017
regulation of fat cell differentiationGO:004559830.017
negative regulation of catalytic activityGO:00430861030.017
response to toxic substanceGO:00096361330.017
regulation of sodium ion transmembrane transporter activityGO:200064940.017
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
ribose phosphate metabolic processGO:00196932350.017
positive regulation of catalytic activityGO:00430851840.017
growthGO:00400071650.017
second messenger mediated signalingGO:0019932510.017
regulation of growthGO:00400081050.017
micturitionGO:006007340.016
response to nicotineGO:0035094510.016
response to testosteroneGO:0033574550.016
multicellular organism reproductionGO:00325042330.016
positive regulation of phosphate metabolic processGO:00459372620.016
response to peptide hormoneGO:00434342780.016
ribose phosphate biosynthetic processGO:0046390870.016
mapk cascadeGO:00001651400.016
cell adhesionGO:00071551100.016
blood vessel morphogenesisGO:0048514580.016
immune system processGO:00023762040.016
regulation of kinase activityGO:00435491170.016
chemotaxisGO:0006935660.016
multicellular organismal signalingGO:0035637440.016
positive regulation of protein metabolic processGO:00512471780.016
transmission of nerve impulseGO:0019226420.015
connective tissue developmentGO:0061448330.015
cellular response to glucocorticoid stimulusGO:0071385680.015
negative regulation of rna metabolic processGO:00512531230.015
carbohydrate derivative metabolic processGO:19011353460.015
forebrain developmentGO:0030900980.015
positive regulation of locomotionGO:00400171020.015
establishment of tissue polarityGO:000716420.015
hormone transportGO:00099141210.015
bile acid biosynthetic processGO:000669930.015
amide transportGO:00428861050.015
regulation of system processGO:00440572080.015
regulation of organelle organizationGO:0033043800.015
gland developmentGO:00487321550.015
oxidation reduction processGO:00551143040.014
regulation of blood pressureGO:0008217830.014
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.014
response to increased oxygen levelsGO:0036296450.014
response to hyperoxiaGO:0055093450.014
cell morphogenesisGO:00009021420.014
regulation of neuron deathGO:19012141150.014
smooth muscle cell proliferationGO:0048659770.014
action potentialGO:0001508540.014
eye morphogenesisGO:004859240.014
positive regulation of epithelial cell proliferationGO:0050679320.014
liver developmentGO:0001889900.014
regulation of establishment of planar polarityGO:009017520.014
biological adhesionGO:00226101100.014
nucleobase containing small molecule metabolic processGO:00550863160.014
synaptic transmission glycinergicGO:006001220.014
reproductionGO:00000032450.014
sequestering of calcium ionGO:005120880.014
benzene containing compound metabolic processGO:0042537220.014
respiratory system developmentGO:0060541450.014
acute inflammatory responseGO:0002526580.014
multicellular organismal reproductive processGO:00486092330.014
cellular calcium ion homeostasisGO:00068741600.014
cellular lipid metabolic processGO:00442552080.014
response to xenobiotic stimulusGO:0009410230.013
response to mechanical stimulusGO:00096121340.013
regulation of dopamine secretionGO:0014059150.013
circulatory system developmentGO:00723591340.013
positive regulation of response to stimulusGO:00485842850.013
positive regulation of signal transductionGO:00099671750.013
negative regulation of protein metabolic processGO:00512481140.013
peptidyl amino acid modificationGO:00181931260.013
sensory perceptionGO:00076001010.013
positive regulation of immune system processGO:0002684900.013
neuron developmentGO:00486662860.013
secretionGO:00469033070.013
regulation of sodium ion transportGO:0002028210.013
erk1 and erk2 cascadeGO:0070371480.013
cellular response to endogenous stimulusGO:00714953770.013
hormone secretionGO:00468791150.013
small gtpase mediated signal transductionGO:0007264360.013
positive regulation of secretionGO:00510471400.013
organic hydroxy compound metabolic processGO:19016151150.013
taxisGO:0042330670.013
cell migrationGO:00164771970.013
regulation of cellular component movementGO:00512701500.013
protein localizationGO:00081041910.013
regulation of blood vessel sizeGO:0050880890.012
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.012
negative regulation of molecular functionGO:00440921330.012
positive regulation of ion transportGO:0043270940.012
synaptic transmissionGO:00072682350.012
regulation of cellular component biogenesisGO:0044087860.012
negative regulation of metabolic processGO:00098923310.012
cellular response to hypoxiaGO:0071456510.012
regulation of mapk cascadeGO:00434081160.012
monoamine transportGO:0015844430.012
behaviorGO:00076102050.012
glutathione transportGO:003463520.012
negative regulation of neuron deathGO:1901215690.012
calcium ion transportGO:00068161310.011
cell projection organizationGO:00300303020.011
insulin secretionGO:0030073690.011
positive regulation of smooth muscle cell proliferationGO:0048661510.011
regulation of cell developmentGO:00602842630.011
peptidyl tyrosine phosphorylationGO:0018108720.011
ras protein signal transductionGO:0007265290.011
neuron deathGO:00709971270.011
cyclic nucleotide metabolic processGO:0009187800.011
purine ribonucleotide metabolic processGO:00091502270.011
developmental process involved in reproductionGO:00030061590.011
protein heterooligomerizationGO:0051291890.011
establishment of planar polarityGO:000173610.011
positive regulation of neurogenesisGO:00507691650.011
regulation of cyclic nucleotide metabolic processGO:0030799510.011
single organism membrane organizationGO:0044802740.011
single organism catabolic processGO:00447122830.011
intracellular transportGO:00469071850.011
proteolysisGO:00065081750.011
peptide hormone secretionGO:0030072840.011
nucleoside phosphate metabolic processGO:00067532830.011
organelle organizationGO:00069962660.011
ribonucleotide biosynthetic processGO:0009260850.011
endocrine system developmentGO:0035270300.011
negative regulation of secretionGO:0051048820.011
regulation of hydrolase activityGO:00513361430.011
cellular macromolecule localizationGO:00707271220.011
multicellular organism growthGO:003526410.011
negative regulation of cellular protein metabolic processGO:00322691060.011
regulation of anatomical structure sizeGO:00900661350.011
endocytosisGO:0006897840.011
regulation of neuron projection developmentGO:00109751610.010
toxin transportGO:190199830.010
cellular response to growth factor stimulusGO:00713631620.010
regulation of immune system processGO:00026821230.010
regulation of cell migrationGO:00303341280.010
maintenance of locationGO:0051235170.010
regulation of leukocyte differentiationGO:1902105200.010
positive regulation of cellular protein metabolic processGO:00322701670.010
smooth muscle cell migrationGO:0014909360.010
response to antibioticGO:0046677390.010
spinal cord developmentGO:0021510270.010
positive regulation of jak stat cascadeGO:0046427190.010
regulation of synaptic transmission glutamatergicGO:0051966260.010
retina development in camera type eyeGO:0060041270.010
regulation of secretionGO:00510462240.010
inorganic anion transportGO:0015698410.010
regulation of protein phosphorylationGO:00019321830.010
peptide transportGO:0015833970.010
cellular response to peptideGO:19016531330.010
regulation of protein kinase activityGO:00458591050.010
protein oligomerizationGO:00512591910.010

Cldn16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.052
disease of anatomical entityDOID:700.052
nervous system diseaseDOID:86300.052
cone rod dystrophyDOID:005057200.020
retinal degenerationDOID:846600.020
retinal diseaseDOID:567900.020
eye diseaseDOID:561400.020
eye and adnexa diseaseDOID:149200.020