Rattus norvegicus

34 known processes

Ppia

peptidylprolyl isomerase A (cyclophilin A)

(Aliases: MGC72881,CYCA)

Ppia biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nitric oxide synthase activityGO:005099980.588
response to ketoneGO:19016541820.548
regulation of high voltage gated calcium channel activityGO:190184130.476
positive regulation of camp metabolic processGO:0030816310.457
porphyrin containing compound biosynthetic processGO:000677960.437
l glutamate importGO:005193820.402
regulation of monooxygenase activityGO:003276880.395
regulation of nucleotide biosynthetic processGO:0030808470.371
positive regulation of nitrogen compound metabolic processGO:00511733340.356
adenine nucleotide transportGO:005150320.345
regulation of transporter activityGO:0032409500.342
regulation of molecular functionGO:00650093980.342
positive regulation of phosphate metabolic processGO:00459372620.329
synaptic growth at neuromuscular junctionGO:005112410.305
cellular ketone metabolic processGO:0042180510.288
positive regulation of phosphorus metabolic processGO:00105622620.287
positive regulation of purine nucleotide biosynthetic processGO:1900373360.279
regulation of transmembrane transportGO:00347621220.250
rna metabolic processGO:00160704060.248
positive regulation of molecular functionGO:00440932300.246
response to corticosteroneGO:0051412400.239
regulation of atp biosynthetic processGO:200116920.232
positive regulation of monooxygenase activityGO:003277050.227
regulation of ryanodine sensitive calcium release channel activityGO:006031450.213
tetrapyrrole biosynthetic processGO:003301470.211
positive regulation of nucleotide metabolic processGO:0045981910.210
regulation of phosphate metabolic processGO:00192203490.187
nucleoside phosphate biosynthetic processGO:19012931020.179
neurotransmitter uptakeGO:000150430.165
camp biosynthetic processGO:0006171470.156
homeostatic processGO:00425923310.153
cellular response to oxidative stressGO:0034599760.153
regulation of cation channel activityGO:2001257230.152
inorganic cation transmembrane transportGO:00986622020.148
transmembrane transportGO:00550854120.148
regulation of purine nucleotide biosynthetic processGO:1900371460.130
macromolecular complex subunit organizationGO:00439333390.130
cation transportGO:00068123820.128
positive regulation of mitochondrial membrane permeabilityGO:003579410.127
ribose phosphate metabolic processGO:00196932350.126
peptidyl amino acid modificationGO:00181931260.124
Human
nucleic acid templated transcriptionGO:00976593790.123
ribose phosphate biosynthetic processGO:0046390870.121
regulation of rna metabolic processGO:00512523910.120
positive regulation of nucleotide biosynthetic processGO:0030810360.120
response to oxidative stressGO:00069791860.119
developmental growthGO:00485891000.118
regulation of nucleotide metabolic processGO:00061401170.115
response to corticosteroidGO:00319602350.112
organophosphate biosynthetic processGO:00904071430.106
positive regulation of cyclase activityGO:0031281150.105
pigment biosynthetic processGO:004614840.103
response to glucocorticoidGO:00513842230.102
ribonucleoside metabolic processGO:00091191740.100
response to amineGO:0014075460.099
organonitrogen compound biosynthetic processGO:19015661670.098
positive regulation of cellular amino acid metabolic processGO:004576410.092
regulation of cellular ketone metabolic processGO:0010565270.091
protein phosphorylationGO:00064683450.091
response to peptideGO:19016522920.091
response to mineralocorticoidGO:0051385490.086
response to acid chemicalGO:00011012220.085
positive regulation of cellular biosynthetic processGO:00313282950.084
positive regulation of nucleobase containing compound metabolic processGO:00459353190.082
positive regulation of catalytic activityGO:00430851840.082
metal ion transportGO:00300012890.080
regulation of calcium ion transmembrane transportGO:1903169180.080
negative regulation of macromolecule biosynthetic processGO:00105581480.079
single organism organelle organizationGO:19025891800.076
regulation of rna biosynthetic processGO:20011413810.076
positive regulation of purine nucleotide metabolic processGO:1900544910.074
cation transmembrane transportGO:00986552630.073
organelle organizationGO:00069962660.073
Human
negative regulation of nitrogen compound metabolic processGO:00511721610.072
ribonucleotide metabolic processGO:00092592310.071
cellular component assemblyGO:00226073600.071
positive regulation of biosynthetic processGO:00098913190.071
cellular component biogenesisGO:00440853680.069
nucleotide metabolic processGO:00091172790.069
carbohydrate derivative biosynthetic processGO:19011371240.069
negative regulation of metabolic processGO:00098923310.064
negative regulation of rna biosynthetic processGO:19026791180.062
cellular response to oxygen containing compoundGO:19017013860.062
regulation of cyclic nucleotide metabolic processGO:0030799510.062
regulation of cellular amine metabolic processGO:003323880.062
positive regulation of camp biosynthetic processGO:0030819280.062
positive regulation of developmental processGO:00510942830.062
regulation of catalytic activityGO:00507903040.061
adult locomotory behaviorGO:000834440.061
organophosphate metabolic processGO:00196373700.057
positive regulation of kinase activityGO:0033674770.057
dna metabolic processGO:0006259960.057
negative regulation of cellular biosynthetic processGO:00313271610.057
positive regulation of multicellular organismal processGO:00512403870.057
ion transmembrane transportGO:00342203650.056
catabolic processGO:00090563510.056
cyclic purine nucleotide metabolic processGO:0052652620.055
regulation of transmembrane transporter activityGO:0022898490.055
amino acid transportGO:0006865700.055
nucleotide biosynthetic processGO:0009165980.054
cellular chemical homeostasisGO:00550822470.053
immune system processGO:00023762040.053
ribonucleoside triphosphate metabolic processGO:00091991410.052
regulation of nucleic acid templated transcriptionGO:19035063800.050
multi organism reproductive processGO:00447032620.050
regulation of neuron apoptotic processGO:0043523830.050
regulation of phosphorus metabolic processGO:00511743490.050
purine ribonucleotide metabolic processGO:00091502270.049
positive regulation of protein phosphorylationGO:00019341350.049
positive regulation of atp biosynthetic processGO:200117120.049
regulation of cellular amino acid metabolic processGO:000652120.048
regulation of cellular component organizationGO:00511283680.048
neuron apoptotic processGO:0051402880.048
positive regulation of cellular amine metabolic processGO:003324030.048
cyclic nucleotide metabolic processGO:0009187800.048
positive regulation of nitric oxide synthase activityGO:005100050.047
camp metabolic processGO:0046058630.047
negative regulation of biosynthetic processGO:00098901680.047
organic acid transportGO:00158491160.047
positive regulation of transferase activityGO:0051347810.047
inorganic ion transmembrane transportGO:00986602290.046
rna biosynthetic processGO:00327743800.046
purine ribonucleotide biosynthetic processGO:0009152810.045
regulation of transcription dna templatedGO:00063553740.045
negative regulation of macromolecule metabolic processGO:00106052600.045
intracellular signal transductionGO:00355563140.045
response to peptide hormoneGO:00434342780.045
neuron projection developmentGO:00311752730.044
membrane organizationGO:0061024940.044
chemical homeostasisGO:00488782920.044
regulation of calcium ion transmembrane transporter activityGO:1901019170.044
heme biosynthetic processGO:000678340.043
cell part morphogenesisGO:00329901230.043
regulation of programmed cell deathGO:00430673410.043
cellular response to endogenous stimulusGO:00714953770.043
negative regulation of cell deathGO:00605482290.043
cell redox homeostasisGO:004545410.042
synaptic transmissionGO:00072682350.042
hair follicle developmentGO:000194220.041
calcium ion transportGO:00068161310.041
regulation of purine nucleotide metabolic processGO:19005421150.041
regulation of cellular localizationGO:00603412630.041
Human
neuron developmentGO:00486662860.040
transcription dna templatedGO:00063513770.040
single organism biosynthetic processGO:00447113420.040
regulation of membrane potentialGO:00423911100.040
positive regulation of transportGO:00510502450.040
Human
macromolecular complex assemblyGO:00650032730.039
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.039
circulatory system processGO:00030131830.038
regulation of intracellular transportGO:0032386650.038
response to thyroxineGO:009706830.038
retinal metabolic processGO:004257430.036
purine nucleotide transportGO:001586530.036
regulation of cyclic nucleotide biosynthetic processGO:0030802450.036
positive regulation of cyclic nucleotide metabolic processGO:0030801370.035
multicellular organismal homeostasisGO:0048871490.034
positive regulation of phosphorylationGO:00423271770.034
nuclear transportGO:0051169490.034
hippocampus developmentGO:0021766300.034
negative regulation of cellular metabolic processGO:00313242810.034
ion homeostasisGO:00508012120.033
cellular homeostasisGO:00197252520.033
nucleoside phosphate metabolic processGO:00067532830.033
regulation of neuron deathGO:19012141150.033
neuron projection morphogenesisGO:00488121220.033
negative regulation of gene expressionGO:00106291990.033
carboxylic acid transportGO:00469421150.033
divalent metal ion transportGO:00708381320.033
negative regulation of transcription dna templatedGO:00458921160.033
anatomical structure homeostasisGO:0060249290.032
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.032
defense responseGO:00069521940.031
regulation of cell developmentGO:00602842630.031
peptidyl serine phosphorylationGO:0018105330.031
organic substance catabolic processGO:19015753160.031
growthGO:00400071650.030
dicarboxylic acid transportGO:0006835340.030
cellular lipid metabolic processGO:00442552080.030
norepinephrine metabolic processGO:004241530.030
cofactor transportGO:005118150.030
positive regulation of transporter activityGO:0032411140.030
positive regulation of ion transportGO:0043270940.029
positive regulation of cell differentiationGO:00455972170.029
purine containing compound metabolic processGO:00725212530.029
regulation of camp biosynthetic processGO:0030817380.029
protein import into nucleusGO:0006606350.029
ribonucleoside triphosphate biosynthetic processGO:000920170.028
regulation of mitochondrial membrane permeabilityGO:004690250.028
regulation of cell proliferationGO:00421273590.028
regulation of phosphorylationGO:00423252480.028
positive regulation of cell proliferationGO:00082842490.028
glycosyl compound biosynthetic processGO:1901659250.027
inflammatory responseGO:00069541500.027
response to monosaccharideGO:00342841590.027
striated muscle contractionGO:0006941440.027
multicellular organism reproductionGO:00325042330.027
cell morphogenesis involved in neuron differentiationGO:00486671060.027
nucleoside transportGO:001585880.027
neuron differentiationGO:00301823680.027
cellular calcium ion homeostasisGO:00068741600.027
salivary gland developmentGO:000743130.026
purine nucleotide biosynthetic processGO:0006164830.026
positive regulation of protein metabolic processGO:00512471780.026
regulation of multicellular organismal developmentGO:20000263760.026
agingGO:00075682410.026
negative regulation of response to stimulusGO:00485851550.025
single organism behaviorGO:00447081300.025
cell projection organizationGO:00300303020.025
regulation of ion transmembrane transporter activityGO:0032412480.025
organelle localizationGO:0051640550.025
regulation of mitochondrion organizationGO:001082170.025
positive regulation of cellular protein metabolic processGO:00322701670.025
amine metabolic processGO:0009308380.025
cellular response to stressGO:00335542690.024
nucleobase containing small molecule metabolic processGO:00550863160.024
reproductionGO:00000032450.024
negative regulation of rna metabolic processGO:00512531230.024
cellular response to peptideGO:19016531330.024
jak stat cascadeGO:0007259260.024
divalent inorganic cation transportGO:00725111340.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
nitrogen compound transportGO:00717052290.023
second messenger mediated signalingGO:0019932510.023
blood circulationGO:00080151830.023
collecting duct developmentGO:007204410.023
response to inorganic substanceGO:00100353770.022
taxisGO:0042330670.022
immune responseGO:00069551040.022
mitochondrial calcium ion homeostasisGO:005156030.022
calcium ion transmembrane transportGO:0070588700.021
positive regulation of protein modification processGO:00314011420.021
regulation of camp metabolic processGO:0030814430.021
response to mechanical stimulusGO:00096121340.021
negative regulation of neuron apoptotic processGO:0043524450.021
anion transportGO:00068201780.021
purine ribonucleoside metabolic processGO:00461281680.021
regulation of protein modification processGO:00313991940.020
carbohydrate derivative metabolic processGO:19011353460.020
purine nucleoside metabolic processGO:00422781690.020
organic anion transportGO:00157111320.020
terpenoid metabolic processGO:0006721370.020
multicellular organismal reproductive processGO:00486092330.020
negative regulation of transportGO:00510511360.019
purine nucleotide metabolic processGO:00061632290.019
adp transportGO:001586610.019
cell morphogenesisGO:00009021420.019
neuron deathGO:00709971270.019
l amino acid importGO:004309250.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
cell activationGO:0001775970.018
peptidyl serine modificationGO:0018209340.018
neurotransmitter transportGO:0006836420.018
programmed cell deathGO:00125013920.018
cell cell signalingGO:00072673350.018
tetrapyrrole metabolic processGO:0033013110.018
cellular amino acid metabolic processGO:00065201070.018
axon developmentGO:0061564960.017
response to hexoseGO:00097461440.017
ribonucleotide biosynthetic processGO:0009260850.017
regulation of protein kinase activityGO:00458591050.017
protein import into nucleus translocationGO:000006090.016
head developmentGO:00603222470.016
ctp biosynthetic processGO:000624110.016
nucleoside metabolic processGO:00091161790.016
positive regulation of lyase activityGO:0051349150.016
organic acid metabolic processGO:00060822920.016
cyclic nucleotide biosynthetic processGO:0009190630.016
response to glucoseGO:00097491360.016
regulation of ion transmembrane transportGO:00347651210.016
regulation of immune system processGO:00026821230.016
establishment of neuroblast polarityGO:004520010.016
purine ribonucleoside biosynthetic processGO:0046129210.015
rho protein signal transductionGO:0007266110.015
regulation of ion transportGO:00432692450.015
central nervous system developmentGO:00074173110.015
protein complex subunit organizationGO:00718223020.015
alditol metabolic processGO:001940040.015
cation homeostasisGO:00550801950.015
cellular carbohydrate metabolic processGO:0044262720.015
dna replicationGO:0006260370.015
regulation of transferase activityGO:00513381230.015
apoptotic processGO:00069153810.014
action potentialGO:0001508540.014
regulation of metal ion transportGO:00109591180.014
acidic amino acid transportGO:0015800100.014
regulation of signal transductionGO:00099663180.014
response to woundingGO:00096112540.014
calcium mediated signalingGO:0019722230.014
positive regulation of lipid kinase activityGO:009021820.014
molting cycleGO:004230330.014
positive regulation of pseudopodium assemblyGO:003127410.013
tube developmentGO:0035295890.013
positive regulation of intracellular signal transductionGO:19025331380.013
regulation of anatomical structure sizeGO:00900661350.013
negative regulation of apoptotic processGO:00430661810.013
positive regulation of response to stimulusGO:00485842850.013
gastrulationGO:000736920.013
sorbitol biosynthetic processGO:000606110.013
telencephalon developmentGO:0021537620.013
mitochondrial transportGO:0006839190.013
innate immune responseGO:0045087350.013
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
cellular response to insulin stimulusGO:0032869810.013
l amino acid transportGO:0015807210.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
multicellular organism growthGO:003526410.013
negative regulation of mitochondrion organizationGO:001082320.013
endocytosisGO:0006897840.013
single organism catabolic processGO:00447122830.013
positive regulation of nucleoside metabolic processGO:0045979550.013
negative regulation of neuron deathGO:1901215690.012
metal ion homeostasisGO:00550651860.012
monovalent inorganic cation transportGO:00156721720.012
regulation of protein phosphorylationGO:00019321830.012
cell growthGO:00160491040.012
regulation of neurotransmitter levelsGO:0001505420.012
mitochondrion organizationGO:0007005350.012
positive regulation of lamellipodium assemblyGO:001059240.012
cellular component movementGO:00069282480.012
isoprenoid metabolic processGO:0006720450.012
regulation of cellular catabolic processGO:00313291010.012
carboxylic acid metabolic processGO:00197522890.012
spliceosomal complex assemblyGO:000024520.011
single organism intracellular transportGO:19025821660.011
protein oligomerizationGO:00512591910.011
regulation of protein metabolic processGO:00512462890.011
purine nucleoside triphosphate biosynthetic processGO:000914560.011
negative regulation of protein modification by small protein conjugation or removalGO:190332140.011
regulation of developmental growthGO:0048638450.011
cellular response to organonitrogen compoundGO:00714171970.011
single organism membrane organizationGO:0044802740.011
regulation of kinase activityGO:00435491170.011
positive regulation of cell communicationGO:00106472710.011
anion transmembrane transportGO:0098656770.011
nucleocytoplasmic transportGO:0006913480.011
regulation of blood circulationGO:19035221100.010
response to hydrogen peroxideGO:0042542890.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
vesicle mediated transportGO:00161921810.010
cellular component morphogenesisGO:00329891550.010
carbohydrate homeostasisGO:0033500750.010
regulation of cyclase activityGO:0031279210.010
heart contractionGO:0060047570.010
pseudopodium assemblyGO:003126930.010
regulation of body fluid levelsGO:0050878900.010

Ppia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone development diseaseDOID:008000600.016
osteochondrodysplasiaDOID:225600.016
bone diseaseDOID:008000100.016
musculoskeletal system diseaseDOID:1700.016
connective tissue diseaseDOID:6500.016
disease of anatomical entityDOID:700.016