| ubiquitin dependent protein catabolic process | GO:0006511 | 14 | 0.609 | Yeast |
| catabolic process | GO:0009056 | 351 | 0.578 | Yeast |
| cellular catabolic process | GO:0044248 | 295 | 0.488 | Yeast |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 7 | 0.391 | Yeast |
| organic substance catabolic process | GO:1901575 | 316 | 0.302 | Yeast |
| proteolysis | GO:0006508 | 175 | 0.273 | Yeast |
| macromolecular complex assembly | GO:0065003 | 273 | 0.271 | Yeast |
| cellular protein catabolic process | GO:0044257 | 19 | 0.260 | Yeast |
| cellular response to stress | GO:0033554 | 269 | 0.231 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.228 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.215 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 14 | 0.182 | Yeast |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.181 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.180 | Yeast |
| protein complex subunit organization | GO:0071822 | 302 | 0.180 | Yeast |
| cell projection organization | GO:0030030 | 302 | 0.169 | |
| mitotic spindle organization | GO:0007052 | 2 | 0.159 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.152 | |
| response to peptide | GO:1901652 | 292 | 0.151 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.149 | |
| reproduction | GO:0000003 | 245 | 0.147 | Worm |
| transcription dna templated | GO:0006351 | 377 | 0.145 | |
| proteasomal protein catabolic process | GO:0010498 | 8 | 0.143 | Yeast |
| protein catabolic process | GO:0030163 | 30 | 0.140 | Yeast |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.138 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.126 | |
| response to oxidative stress | GO:0006979 | 186 | 0.124 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.124 | |
| single organism reproductive process | GO:0044702 | 297 | 0.122 | |
| rna metabolic process | GO:0016070 | 406 | 0.121 | |
| aromatic compound catabolic process | GO:0019439 | 168 | 0.121 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.118 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.116 | |
| regulation of molecular function | GO:0065009 | 398 | 0.114 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.114 | |
| reproductive process | GO:0022414 | 372 | 0.109 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.109 | |
| protein complex assembly | GO:0006461 | 263 | 0.108 | Yeast |
| cellular component assembly | GO:0022607 | 360 | 0.105 | Yeast |
| neuron projection development | GO:0031175 | 273 | 0.103 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.099 | |
| locomotion | GO:0040011 | 237 | 0.099 | Worm |
| cellular component biogenesis | GO:0044085 | 368 | 0.095 | Yeast |
| neuron differentiation | GO:0030182 | 368 | 0.094 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.093 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.082 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 19 | 0.082 | Yeast |
| aging | GO:0007568 | 241 | 0.074 | Worm |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.073 | |
| cellular homeostasis | GO:0019725 | 252 | 0.072 | |
| apoptotic process | GO:0006915 | 381 | 0.071 | |
| cellular macromolecule catabolic process | GO:0044265 | 29 | 0.069 | Yeast |
| rna biosynthetic process | GO:0032774 | 380 | 0.069 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.068 | |
| protein ubiquitination | GO:0016567 | 28 | 0.068 | |
| response to inorganic substance | GO:0010035 | 377 | 0.065 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.062 | |
| neuron development | GO:0048666 | 286 | 0.058 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.056 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.053 | |
| macromolecule catabolic process | GO:0009057 | 58 | 0.051 | Yeast |
| cellular response to reactive oxygen species | GO:0034614 | 55 | 0.051 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.049 | |
| chemical homeostasis | GO:0048878 | 292 | 0.049 | |
| purine nucleotide catabolic process | GO:0006195 | 136 | 0.047 | |
| macromolecule localization | GO:0033036 | 252 | 0.047 | |
| response to hydrogen peroxide | GO:0042542 | 89 | 0.047 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.047 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.045 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.045 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.045 | |
| regulation of protein kinase activity | GO:0045859 | 105 | 0.045 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.044 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.044 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.043 | |
| ribonucleoside catabolic process | GO:0042454 | 126 | 0.041 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.041 | Yeast |
| multicellular organism reproduction | GO:0032504 | 233 | 0.040 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.040 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.039 | |
| calcium ion transport | GO:0006816 | 131 | 0.038 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.038 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 140 | 0.038 | |
| response to reactive oxygen species | GO:0000302 | 120 | 0.037 | |
| purine nucleoside catabolic process | GO:0006152 | 124 | 0.037 | |
| single organism catabolic process | GO:0044712 | 283 | 0.037 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.037 | |
| programmed cell death | GO:0012501 | 392 | 0.037 | |
| response to carbohydrate | GO:0009743 | 183 | 0.036 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.036 | |
| endocytic recycling | GO:0032456 | 2 | 0.035 | |
| glycosyl compound metabolic process | GO:1901657 | 182 | 0.035 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.034 | |
| spliceosomal complex assembly | GO:0000245 | 2 | 0.034 | |
| regulation of neuron death | GO:1901214 | 115 | 0.033 | |
| protein oligomerization | GO:0051259 | 191 | 0.033 | |
| regulation of catabolic process | GO:0009894 | 113 | 0.033 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.033 | |
| organophosphate catabolic process | GO:0046434 | 148 | 0.033 | |
| organelle organization | GO:0006996 | 266 | 0.033 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 148 | 0.033 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.033 | |
| protein modification by small protein conjugation | GO:0032446 | 31 | 0.031 | |
| homeostatic process | GO:0042592 | 331 | 0.031 | |
| ctp metabolic process | GO:0046036 | 1 | 0.031 | |
| spindle organization | GO:0007051 | 2 | 0.031 | |
| regulation of cell development | GO:0060284 | 263 | 0.031 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.031 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.030 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.029 | |
| negative regulation of myeloid cell differentiation | GO:0045638 | 3 | 0.029 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.029 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.029 | |
| protein localization | GO:0008104 | 191 | 0.028 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.028 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.027 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.027 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.027 | |
| secretion | GO:0046903 | 307 | 0.027 | |
| tissue development | GO:0009888 | 252 | 0.027 | |
| protein phosphorylation | GO:0006468 | 345 | 0.026 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.026 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.026 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.025 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.025 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.024 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.024 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.024 | |
| blood circulation | GO:0008015 | 183 | 0.024 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 122 | 0.024 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.024 | |
| response to ketone | GO:1901654 | 182 | 0.024 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.024 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.023 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.023 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.023 | |
| response to peptide hormone | GO:0043434 | 278 | 0.023 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.023 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.022 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 123 | 0.022 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.022 | |
| pyrimidine nucleotide metabolic process | GO:0006220 | 9 | 0.022 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.021 | |
| regulation of immune system process | GO:0002682 | 123 | 0.021 | Mouse |
| purine ribonucleoside catabolic process | GO:0046130 | 124 | 0.021 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.021 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.021 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.021 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.021 | |
| purine ribonucleotide catabolic process | GO:0009154 | 136 | 0.021 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.020 | |
| response to external biotic stimulus | GO:0043207 | 221 | 0.020 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.020 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.020 | |
| response to glucose | GO:0009749 | 136 | 0.019 | |
| response to wounding | GO:0009611 | 254 | 0.019 | Mouse |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.019 | |
| amine metabolic process | GO:0009308 | 38 | 0.019 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.019 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.019 | |
| nucleotide catabolic process | GO:0009166 | 139 | 0.018 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.018 | |
| immune system process | GO:0002376 | 204 | 0.018 | Mouse |
| response to hexose | GO:0009746 | 144 | 0.018 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.017 | |
| negative regulation of inflammatory response to antigenic stimulus | GO:0002862 | 1 | 0.017 | Mouse |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.017 | |
| intestinal epithelial structure maintenance | GO:0060729 | 1 | 0.017 | |
| response to monosaccharide | GO:0034284 | 159 | 0.017 | |
| regulation of response to stress | GO:0080134 | 126 | 0.017 | Mouse |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.017 | |
| peptidyl cysteine modification | GO:0018198 | 2 | 0.017 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.017 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.017 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.016 | |
| regulation of system process | GO:0044057 | 208 | 0.016 | |
| regulation of cyclic nucleotide phosphodiesterase activity | GO:0051342 | 4 | 0.016 | |
| organophosphate biosynthetic process | GO:0090407 | 143 | 0.016 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.016 | |
| response to ethanol | GO:0045471 | 162 | 0.016 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.016 | |
| intracellular transport | GO:0046907 | 185 | 0.016 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 35 | 0.016 | |
| single organism organelle organization | GO:1902589 | 180 | 0.016 | |
| cation transport | GO:0006812 | 382 | 0.015 | |
| oxidation reduction process | GO:0055114 | 304 | 0.015 | |
| negative regulation of transport | GO:0051051 | 136 | 0.015 | |
| regulation of nucleotide metabolic process | GO:0006140 | 117 | 0.015 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.015 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 122 | 0.015 | |
| ossification | GO:0001503 | 70 | 0.015 | |
| sertoli cell differentiation | GO:0060008 | 11 | 0.015 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.015 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.015 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.015 | |
| regulation of hydrolase activity | GO:0051336 | 143 | 0.015 | |
| protein localization to cell surface | GO:0034394 | 1 | 0.015 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.015 | |
| embryo development | GO:0009790 | 49 | 0.014 | Worm |
| cellular response to dna damage stimulus | GO:0006974 | 19 | 0.014 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.014 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.014 | |
| reproductive structure development | GO:0048608 | 128 | 0.014 | |
| response to nutrient levels | GO:0031667 | 370 | 0.014 | |
| positive regulation of peptidyl threonine phosphorylation | GO:0010800 | 1 | 0.014 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 144 | 0.014 | |
| response to other organism | GO:0051707 | 220 | 0.014 | |
| response to camp | GO:0051591 | 91 | 0.013 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.013 | |
| nucleoside catabolic process | GO:0009164 | 126 | 0.013 | |
| maintenance of protein localization in organelle | GO:0072595 | 1 | 0.013 | |
| regulation of proteolysis | GO:0030162 | 66 | 0.013 | |
| sexual reproduction | GO:0019953 | 148 | 0.013 | |
| microtubule based process | GO:0007017 | 36 | 0.013 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.013 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.013 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.013 | |
| cell cycle | GO:0007049 | 101 | 0.013 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.012 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.012 | |
| nucleoside phosphate catabolic process | GO:1901292 | 140 | 0.012 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.012 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 1 | 0.012 | |
| copper ion transmembrane transport | GO:0035434 | 5 | 0.012 | |
| copper ion transport | GO:0006825 | 6 | 0.012 | |
| glycosyl compound catabolic process | GO:1901658 | 126 | 0.012 | |
| regulation of calcium ion transport | GO:0051924 | 77 | 0.012 | |
| regulation of insulin secretion involved in cellular response to glucose stimulus | GO:0061178 | 14 | 0.012 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.012 | |
| guanosine containing compound metabolic process | GO:1901068 | 74 | 0.012 | |
| microtubule cytoskeleton organization | GO:0000226 | 25 | 0.012 | |
| histone h3 deacetylation | GO:0070932 | 6 | 0.012 | |
| protein autoubiquitination | GO:0051865 | 2 | 0.012 | |
| heart contraction | GO:0060047 | 57 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.011 | |
| reproductive system development | GO:0061458 | 128 | 0.011 | |
| positive regulation of phosphatase activity | GO:0010922 | 7 | 0.011 | |
| carbohydrate homeostasis | GO:0033500 | 75 | 0.011 | |
| modification dependent protein catabolic process | GO:0019941 | 14 | 0.011 | Yeast |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.011 | |
| protein transport | GO:0015031 | 132 | 0.011 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.011 | |
| ribonucleoside metabolic process | GO:0009119 | 174 | 0.011 | |
| ribonucleotide catabolic process | GO:0009261 | 136 | 0.011 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.011 | |
| cellular response to hydrogen peroxide | GO:0070301 | 42 | 0.011 | |
| cellular response to carbohydrate stimulus | GO:0071322 | 72 | 0.011 | |
| regulation of cellular catabolic process | GO:0031329 | 101 | 0.011 | |
| dorsal ventral pattern formation | GO:0009953 | 4 | 0.011 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.011 | |
| regulation of ion homeostasis | GO:2000021 | 63 | 0.011 | |
| negative regulation of developmental process | GO:0051093 | 125 | 0.010 | |
| regulation of humoral immune response mediated by circulating immunoglobulin | GO:0002923 | 1 | 0.010 | |
| glucose homeostasis | GO:0042593 | 75 | 0.010 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.010 | |
| cation homeostasis | GO:0055080 | 195 | 0.010 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 116 | 0.010 | |