| carboxylic acid metabolic process | GO:0019752 | 289 | 0.216 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.203 | |
| alpha amino acid metabolic process | GO:1901605 | 71 | 0.196 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.183 | |
| alpha amino acid catabolic process | GO:1901606 | 20 | 0.161 | |
| cellular amino acid catabolic process | GO:0009063 | 21 | 0.090 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.074 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.071 | |
| single organism catabolic process | GO:0044712 | 283 | 0.070 | |
| catabolic process | GO:0009056 | 351 | 0.070 | |
| valine metabolic process | GO:0006573 | 1 | 0.059 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.058 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.052 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.050 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.049 | |
| cellular catabolic process | GO:0044248 | 295 | 0.047 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.044 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.044 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.043 | |
| small molecule catabolic process | GO:0044282 | 59 | 0.043 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.043 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.042 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.042 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.041 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.041 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.041 | |
| cofactor metabolic process | GO:0051186 | 95 | 0.041 | |
| branched chain amino acid metabolic process | GO:0009081 | 4 | 0.040 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.040 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.039 | |
| ion transmembrane transport | GO:0034220 | 365 | 0.039 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.038 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.038 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.037 | |
| amine metabolic process | GO:0009308 | 38 | 0.036 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.035 | |
| regulation of molecular function | GO:0065009 | 398 | 0.035 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 1 | 0.034 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.034 | |
| transmembrane transport | GO:0055085 | 412 | 0.033 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.033 | |
| positive regulation of cell differentiation | GO:0045597 | 217 | 0.033 | |
| regulation of secretion | GO:0051046 | 224 | 0.032 | |
| protein phosphorylation | GO:0006468 | 345 | 0.032 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.032 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.032 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.032 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.032 | |
| mapk cascade | GO:0000165 | 140 | 0.030 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.029 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.029 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.029 | |
| neuron development | GO:0048666 | 286 | 0.028 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 85 | 0.028 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.028 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.028 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.027 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.027 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.027 | |
| cation transport | GO:0006812 | 382 | 0.026 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.026 | |
| neuron differentiation | GO:0030182 | 368 | 0.026 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.026 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.025 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.025 | |
| cellular cation homeostasis | GO:0030003 | 180 | 0.025 | |
| organic acid catabolic process | GO:0016054 | 49 | 0.025 | |
| transcription dna templated | GO:0006351 | 377 | 0.025 | |
| carboxylic acid catabolic process | GO:0046395 | 49 | 0.025 | |
| sulfur compound biosynthetic process | GO:0044272 | 19 | 0.024 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.024 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.024 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.024 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.024 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.024 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.023 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.023 | |
| rna metabolic process | GO:0016070 | 406 | 0.023 | |
| regulation of kinase activity | GO:0043549 | 117 | 0.023 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.023 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.023 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.023 | |
| central nervous system development | GO:0007417 | 311 | 0.022 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.022 | |
| cellular response to stress | GO:0033554 | 269 | 0.022 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.022 | |
| response to nutrient levels | GO:0031667 | 370 | 0.022 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.022 | |
| response to oxygen levels | GO:0070482 | 265 | 0.021 | |
| neuron projection development | GO:0031175 | 273 | 0.021 | |
| regulation of catabolic process | GO:0009894 | 113 | 0.021 | |
| cellular response to insulin stimulus | GO:0032869 | 81 | 0.021 | |
| positive regulation of triglyceride biosynthetic process | GO:0010867 | 4 | 0.021 | |
| pyrimidine nucleobase catabolic process | GO:0006208 | 3 | 0.021 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.021 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.021 | |
| regulation of ion transport | GO:0043269 | 245 | 0.021 | |
| lipid metabolic process | GO:0006629 | 283 | 0.021 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.020 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.020 | |
| divalent metal ion transport | GO:0070838 | 132 | 0.020 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.020 | |
| positive regulation of kinase activity | GO:0033674 | 77 | 0.020 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.020 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.019 | |
| regulation of mapk cascade | GO:0043408 | 116 | 0.019 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.019 | |
| branched chain amino acid catabolic process | GO:0009083 | 4 | 0.019 | |
| cation homeostasis | GO:0055080 | 195 | 0.019 | |
| programmed cell death | GO:0012501 | 392 | 0.019 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.019 | |
| apoptotic process | GO:0006915 | 381 | 0.019 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.019 | |
| ion homeostasis | GO:0050801 | 212 | 0.019 | |
| serine family amino acid metabolic process | GO:0009069 | 12 | 0.019 | |
| coenzyme metabolic process | GO:0006732 | 86 | 0.019 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.019 | |
| chemical homeostasis | GO:0048878 | 292 | 0.019 | |
| anion transmembrane transport | GO:0098656 | 77 | 0.019 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.019 | |
| response to alkaloid | GO:0043279 | 132 | 0.018 | |
| response to growth factor | GO:0070848 | 189 | 0.018 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.018 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.018 | |
| homeostatic process | GO:0042592 | 331 | 0.018 | |
| insulin like growth factor receptor signaling pathway | GO:0048009 | 3 | 0.018 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.018 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.018 | |
| reproduction | GO:0000003 | 245 | 0.017 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.017 | |
| cell projection organization | GO:0030030 | 302 | 0.017 | |
| carboxylic acid transport | GO:0046942 | 115 | 0.017 | |
| positive regulation of mapk cascade | GO:0043410 | 92 | 0.017 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.017 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.017 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.017 | |
| secretion | GO:0046903 | 307 | 0.017 | |
| metal ion transport | GO:0030001 | 289 | 0.017 | |
| regulation of secretion by cell | GO:1903530 | 208 | 0.017 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.017 | |
| regulation of protein kinase activity | GO:0045859 | 105 | 0.017 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.017 | |
| positive regulation of cell development | GO:0010720 | 176 | 0.017 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.017 | |
| response to inorganic substance | GO:0010035 | 377 | 0.016 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.016 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.016 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.016 | |
| anion transport | GO:0006820 | 178 | 0.016 | |
| positive regulation of fatty acid beta oxidation | GO:0032000 | 4 | 0.016 | |
| brain development | GO:0007420 | 247 | 0.016 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.016 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.016 | |
| macromolecule localization | GO:0033036 | 252 | 0.016 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.016 | |
| positive regulation of protein phosphorylation | GO:0001934 | 135 | 0.016 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.016 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.016 | |
| aging | GO:0007568 | 241 | 0.016 | |
| response to purine containing compound | GO:0014074 | 126 | 0.016 | |
| carbohydrate metabolic process | GO:0005975 | 130 | 0.016 | |
| chromosome segregation | GO:0007059 | 2 | 0.016 | |
| regulation of cell development | GO:0060284 | 263 | 0.015 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.015 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.015 | |
| glycosyl compound metabolic process | GO:1901657 | 182 | 0.015 | |
| pyrimidine nucleobase metabolic process | GO:0006206 | 8 | 0.015 | |
| positive regulation of neurogenesis | GO:0050769 | 165 | 0.015 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.015 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.015 | |
| ribonucleoside metabolic process | GO:0009119 | 174 | 0.015 | |
| axis specification | GO:0009798 | 4 | 0.015 | |
| neurological system process | GO:0050877 | 219 | 0.015 | |
| neuronal action potential | GO:0019228 | 35 | 0.015 | |
| response to aluminum ion | GO:0010044 | 10 | 0.015 | |
| positive regulation of catabolic process | GO:0009896 | 78 | 0.015 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.015 | |
| heart morphogenesis | GO:0003007 | 3 | 0.015 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.015 | |
| response to peptide hormone | GO:0043434 | 278 | 0.015 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 116 | 0.015 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.014 | |
| glycosyl compound catabolic process | GO:1901658 | 126 | 0.014 | |
| positive regulation of nervous system development | GO:0051962 | 178 | 0.014 | |
| dephosphorylation | GO:0016311 | 98 | 0.014 | |
| fatty acid catabolic process | GO:0009062 | 26 | 0.014 | |
| positive regulation of transferase activity | GO:0051347 | 81 | 0.014 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.014 | |
| cellular lipid metabolic process | GO:0044255 | 208 | 0.014 | |
| cellular homeostasis | GO:0019725 | 252 | 0.014 | |
| regulation of cellular catabolic process | GO:0031329 | 101 | 0.014 | |
| organic anion transport | GO:0015711 | 132 | 0.014 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.014 | |
| retinal metabolic process | GO:0042574 | 3 | 0.014 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.014 | |
| aromatic compound catabolic process | GO:0019439 | 168 | 0.014 | |
| reproductive process | GO:0022414 | 372 | 0.014 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.014 | |
| negative regulation of transport | GO:0051051 | 136 | 0.014 | |
| organic acid transport | GO:0015849 | 116 | 0.013 | |
| positive regulation of cellular catabolic process | GO:0031331 | 71 | 0.013 | |
| regulation of cell projection organization | GO:0031344 | 175 | 0.013 | |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.013 | |
| peptidyl amino acid modification | GO:0018193 | 126 | 0.013 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.013 | |
| response to metal ion | GO:0010038 | 253 | 0.013 | |
| behavior | GO:0007610 | 205 | 0.013 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.013 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.013 | |
| cytokine mediated signaling pathway | GO:0019221 | 43 | 0.013 | |
| cell part morphogenesis | GO:0032990 | 123 | 0.013 | |
| response to acid chemical | GO:0001101 | 222 | 0.013 | |
| blood circulation | GO:0008015 | 183 | 0.013 | |
| response to peptide | GO:1901652 | 292 | 0.013 | |
| cellular response to cytokine stimulus | GO:0071345 | 127 | 0.013 | |
| regulation of transmembrane transport | GO:0034762 | 122 | 0.013 | |
| cell adhesion | GO:0007155 | 110 | 0.013 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.013 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 72 | 0.013 | |
| cell cycle checkpoint | GO:0000075 | 2 | 0.013 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.012 | |
| cellular component assembly | GO:0022607 | 360 | 0.012 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 162 | 0.012 | |
| response to carbohydrate | GO:0009743 | 183 | 0.012 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.012 | |
| single organism reproductive process | GO:0044702 | 297 | 0.012 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 4 | 0.012 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.012 | |
| positive regulation of transport | GO:0051050 | 245 | 0.012 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.012 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.012 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.012 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.012 | |
| positive regulation of neuron differentiation | GO:0045666 | 126 | 0.012 | |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.012 | |
| regulation of homeostatic process | GO:0032844 | 101 | 0.012 | |
| response to ketone | GO:1901654 | 182 | 0.012 | |
| lipid biosynthetic process | GO:0008610 | 128 | 0.012 | |
| regulation of gtpase activity | GO:0043087 | 57 | 0.012 | |
| multicellular organism growth | GO:0035264 | 1 | 0.012 | |
| ribonucleoside catabolic process | GO:0042454 | 126 | 0.012 | |
| response to monosaccharide | GO:0034284 | 159 | 0.012 | |
| multicellular organismal signaling | GO:0035637 | 44 | 0.012 | |
| regulation of ion transmembrane transport | GO:0034765 | 121 | 0.012 | |
| cell type specific apoptotic process | GO:0097285 | 134 | 0.011 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 124 | 0.011 | |
| guanosine containing compound metabolic process | GO:1901068 | 74 | 0.011 | |
| peptidyl tyrosine modification | GO:0018212 | 72 | 0.011 | |
| single organism organelle organization | GO:1902589 | 180 | 0.011 | |
| proteolysis | GO:0006508 | 175 | 0.011 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.011 | |
| small molecule biosynthetic process | GO:0044283 | 124 | 0.011 | |
| single organism carbohydrate metabolic process | GO:0044723 | 118 | 0.011 | |
| gtp metabolic process | GO:0046039 | 72 | 0.011 | |
| regulation of locomotion | GO:0040012 | 148 | 0.011 | |
| motor neuron axon guidance | GO:0008045 | 1 | 0.011 | |
| skeletal system development | GO:0001501 | 41 | 0.011 | |
| cellular calcium ion homeostasis | GO:0006874 | 160 | 0.011 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 64 | 0.011 | |
| positive regulation of signaling | GO:0023056 | 270 | 0.011 | |
| response to cytokine | GO:0034097 | 215 | 0.011 | |
| cell cell signaling | GO:0007267 | 335 | 0.011 | |
| action potential | GO:0001508 | 54 | 0.011 | |
| lipid storage | GO:0019915 | 1 | 0.011 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.011 | |
| positive regulation of cell projection organization | GO:0031346 | 111 | 0.011 | |
| head development | GO:0060322 | 247 | 0.011 | |
| transmission of nerve impulse | GO:0019226 | 42 | 0.011 | |
| regulation of lipid metabolic process | GO:0019216 | 68 | 0.011 | |
| response to corticosteroid | GO:0031960 | 235 | 0.011 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 167 | 0.011 | |
| beta alanine metabolic process | GO:0019482 | 3 | 0.011 | |
| signal transduction by phosphorylation | GO:0023014 | 144 | 0.011 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 91 | 0.011 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.011 | |
| reproductive structure development | GO:0048608 | 128 | 0.011 | |
| inorganic cation transmembrane transport | GO:0098662 | 202 | 0.011 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.010 | |
| circulatory system process | GO:0003013 | 183 | 0.010 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 120 | 0.010 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 141 | 0.010 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.010 | |
| gastrulation | GO:0007369 | 2 | 0.010 | |
| regulation of cellular component movement | GO:0051270 | 150 | 0.010 | |
| dendrite development | GO:0016358 | 72 | 0.010 | |
| secretion by cell | GO:0032940 | 248 | 0.010 | |
| regulation of organelle organization | GO:0033043 | 80 | 0.010 | |
| inorganic ion transmembrane transport | GO:0098660 | 229 | 0.010 | |
| positive regulation of gtp catabolic process | GO:0033126 | 48 | 0.010 | |
| positive regulation of cell migration | GO:0030335 | 96 | 0.010 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.010 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.010 | |
| monosaccharide metabolic process | GO:0005996 | 61 | 0.010 | |
| kidney development | GO:0001822 | 67 | 0.010 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.010 | |
| positive regulation of protein kinase activity | GO:0045860 | 73 | 0.010 | |
| nucleoside catabolic process | GO:0009164 | 126 | 0.010 | |
| phospholipid metabolic process | GO:0006644 | 61 | 0.010 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.010 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.010 | |