Rattus norvegicus

0 known processes

Hcn1

hyperpolarization-activated cyclic nucleotide-gated potassium channel 1

Hcn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
head developmentGO:00603222470.655
Rat
brain developmentGO:00074202470.599
Rat
behaviorGO:00076102050.577
central nervous system developmentGO:00074173110.286
Rat
protein complex subunit organizationGO:00718223020.269
Rat
synaptic transmissionGO:00072682350.255
cation transportGO:00068123820.248
Human Mouse Rat
inorganic ion transmembrane transportGO:00986602290.227
Human Mouse
cell cell signalingGO:00072673350.187
macromolecular complex subunit organizationGO:00439333390.187
Rat
single organism behaviorGO:00447081300.182
g protein coupled receptor signaling pathwayGO:00071862420.154
action potentialGO:0001508540.146
cellular component assemblyGO:00226073600.140
Rat
cellular amino acid biosynthetic processGO:0008652320.126
cellular component biogenesisGO:00440853680.125
Rat
phasic smooth muscle contractionGO:001482130.124
neurological system processGO:00508772190.121
lipid metabolic processGO:00066292830.119
organic hydroxy compound metabolic processGO:19016151150.107
cellular cation homeostasisGO:00300031800.102
Rat
homeostatic processGO:00425923310.097
Rat
cation transmembrane transportGO:00986552630.095
Human Mouse Rat
regulation of cellular component organizationGO:00511283680.094
organic substance catabolic processGO:19015753160.094
oxoacid metabolic processGO:00434362900.093
cation homeostasisGO:00550801950.093
Rat
metal ion transportGO:00300012890.084
Human Mouse
hormone transportGO:00099141210.083
regulation of nervous system developmentGO:00519602640.081
signal releaseGO:00230611450.080
forebrain developmentGO:0030900980.079
carboxylic acid metabolic processGO:00197522890.079
positive regulation of nitrogen compound metabolic processGO:00511733340.078
intracellular signal transductionGO:00355563140.076
regulation of synaptic transmissionGO:00508041410.076
learning or memoryGO:0007611900.075
macromolecular complex assemblyGO:00650032730.072
Rat
single organism biosynthetic processGO:00447113420.070
response to inorganic substanceGO:00100353770.070
cellular ketone metabolic processGO:0042180510.070
organophosphate metabolic processGO:00196373700.069
regulation of membrane potentialGO:00423911100.068
Human
peristalsisGO:003043220.068
phototransduction visible lightGO:000760320.067
organic cyclic compound catabolic processGO:19013611750.067
neuron differentiationGO:00301823680.067
Mouse
adult locomotory behaviorGO:000834440.066
glucocorticoid biosynthetic processGO:000670450.066
reproductionGO:00000032450.066
inorganic cation transmembrane transportGO:00986622020.065
Human Mouse
organic acid metabolic processGO:00060822920.064
urinary bladder smooth muscle contractionGO:001483240.064
regulation of phosphate metabolic processGO:00192203490.063
negative regulation of signalingGO:00230571570.063
chemical homeostasisGO:00488782920.063
Rat
regulation of hormone secretionGO:00468831060.061
nitrogen compound transportGO:00717052290.060
regulation of peptide hormone secretionGO:0090276800.060
cellular amino acid metabolic processGO:00065201070.059
purine containing compound metabolic processGO:00725212530.058
vesicle mediated transportGO:00161921810.057
regulation of secretionGO:00510462240.056
ion transmembrane transportGO:00342203650.054
Human Mouse Rat
response to reactive oxygen speciesGO:00003021200.054
protein complex assemblyGO:00064612630.054
Rat
monovalent inorganic cation transportGO:00156721720.053
Human Mouse
regulation of hormone levelsGO:00108171870.053
amine metabolic processGO:0009308380.052
negative regulation of secretion by cellGO:1903531720.052
secretionGO:00469033070.052
lipid biosynthetic processGO:00086101280.052
cellular lipid metabolic processGO:00442552080.052
cellular amine metabolic processGO:0044106380.050
protein complex biogenesisGO:00702712630.050
Rat
single organism reproductive processGO:00447022970.049
neuron developmentGO:00486662860.048
Mouse
positive regulation of biosynthetic processGO:00098913190.048
agingGO:00075682410.048
Rat
neurotransmitter transportGO:0006836420.048
establishment of organelle localizationGO:0051656370.047
carbohydrate derivative metabolic processGO:19011353460.047
nucleobase containing small molecule metabolic processGO:00550863160.045
cellular homeostasisGO:00197252520.045
Rat
rhythmic processGO:00485111560.044
positive regulation of cellular biosynthetic processGO:00313282950.044
cell motilityGO:00488702020.044
locomotionGO:00400112370.043
regulation of locomotionGO:00400121480.042
response to ethanolGO:00454711620.042
detection of visible lightGO:000958430.042
regulation of peptide transportGO:0090087870.041
response to growth factorGO:00708481890.041
response to insecticideGO:0017085210.040
regulation of vesicle mediated transportGO:0060627810.040
sensory organ developmentGO:0007423740.038
Mouse
regulation of cell developmentGO:00602842630.038
organic acid transportGO:00158491160.038
positive regulation of cell communicationGO:00106472710.038
micturitionGO:006007340.037
positive regulation of transcription dna templatedGO:00458931970.037
positive regulation of transportGO:00510502450.037
organelle organizationGO:00069962660.037
regulation of cellular ketone metabolic processGO:0010565270.037
positive regulation of neurogenesisGO:00507691650.036
nucleic acid templated transcriptionGO:00976593790.036
regulation of heart contractionGO:0008016480.036
Rat
ribonucleotide catabolic processGO:00092611360.036
response to extracellular stimulusGO:00099913800.035
cellular response to growth factor stimulusGO:00713631620.035
feeding behaviorGO:0007631530.035
positive regulation of nervous system developmentGO:00519621780.035
response to alkaloidGO:00432791320.035
negative regulation of cell communicationGO:00106481580.035
positive regulation of saliva secretionGO:004687830.035
hormone secretionGO:00468791150.035
organic acid biosynthetic processGO:0016053830.035
single organism organelle organizationGO:19025891800.034
regulation of cellular amine metabolic processGO:003323880.034
cognitionGO:0050890920.034
reproductive processGO:00224143720.034
neuropeptide signaling pathwayGO:0007218290.034
regulation of peptide secretionGO:0002791820.034
ion homeostasisGO:00508012120.034
Rat
response to molecule of bacterial originGO:00022371940.033
pancreatic a cell differentiationGO:000331010.033
regulation of ion transportGO:00432692450.033
Human Mouse
glycerolipid metabolic processGO:0046486670.033
multi organism reproductive processGO:00447032620.033
amide transportGO:00428861050.032
cellular chemical homeostasisGO:00550822470.032
Rat
regulation of cellular localizationGO:00603412630.032
transmission of nerve impulseGO:0019226420.032
eye morphogenesisGO:004859240.032
Mouse
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathwayGO:000719650.031
cellular response to oxygen containing compoundGO:19017013860.031
Human Mouse
somatostatin receptor signaling pathwayGO:003816940.031
cellular response to lipidGO:00713962010.030
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.030
negative regulation of vesicle fusionGO:003133920.030
regulation of neuron projection developmentGO:00109751610.029
regulation of cell differentiationGO:00455953200.029
saliva secretionGO:004654130.029
heterocycle catabolic processGO:00467001670.029
response to ammonium ionGO:0060359710.029
organonitrogen compound biosynthetic processGO:19015661670.029
ribonucleotide metabolic processGO:00092592310.029
ribose phosphate metabolic processGO:00196932350.028
positive regulation of macromolecule biosynthetic processGO:00105572470.028
learningGO:0007612330.028
regulation of saliva secretionGO:004687730.028
cellular metal ion homeostasisGO:00068751720.028
Rat
potassium ion homeostasisGO:005507520.028
gonad developmentGO:00084061040.027
secretion by cellGO:00329402480.027
aromatic compound catabolic processGO:00194391680.027
amino acid transportGO:0006865700.027
positive regulation of rna metabolic processGO:00512542030.026
multicellular organismal signalingGO:0035637440.026
cellular catabolic processGO:00442482950.026
sensory perceptionGO:00076001010.026
regulation of cell migrationGO:00303341280.026
protein homooligomerizationGO:0051260910.026
cellular response to histamineGO:007142030.026
urinary tract smooth muscle contractionGO:001484840.026
negative regulation of response to stimulusGO:00485851550.026
multicellular organism growthGO:003526410.026
telencephalon developmentGO:0021537620.025
regulation of phosphorus metabolic processGO:00511743490.025
response to decreased oxygen levelsGO:00362932370.025
regulation of neurogenesisGO:00507672470.025
regulation of molecular functionGO:00650093980.025
cytoplasmic transportGO:00164821150.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
neuronal action potentialGO:0019228350.024
cellular response to ammonium ionGO:0071242170.024
regulation of organelle organizationGO:0033043800.024
insulin secretionGO:0030073690.024
cellular calcium ion homeostasisGO:00068741600.023
Rat
rna metabolic processGO:00160704060.023
purine ribonucleotide metabolic processGO:00091502270.023
response to estrogenGO:00436272320.023
neuron projection developmentGO:00311752730.023
positive regulation of cell differentiationGO:00455972170.023
purine nucleotide metabolic processGO:00061632290.023
peptide transportGO:0015833970.023
locomotory behaviorGO:0007626150.023
negative regulation of transportGO:00510511360.023
intracellular transportGO:00469071850.023
blood circulationGO:00080151830.023
Rat
purine nucleoside metabolic processGO:00422781690.023
ovulation cycleGO:0042698670.023
multicellular organism reproductionGO:00325042330.023
cellular response to abiotic stimulusGO:0071214850.023
regulation of system processGO:00440572080.022
Rat
response to acid chemicalGO:00011012220.022
response to histamineGO:003477630.022
phosphatidylinositol dephosphorylationGO:004685640.022
nucleoside phosphate metabolic processGO:00067532830.022
peptide hormone secretionGO:0030072840.022
nucleoside metabolic processGO:00091161790.022
cellular response to endogenous stimulusGO:00714953770.022
Human Mouse
calcium ion homeostasisGO:00550741620.022
Rat
cell projection organizationGO:00300303020.022
regulation of transcription dna templatedGO:00063553740.022
peptide secretionGO:0002790860.022
regulation of neurotransmitter levelsGO:0001505420.022
organic anion transportGO:00157111320.021
cyclic nucleotide metabolic processGO:0009187800.021
positive regulation of gene expressionGO:00106282440.021
single organism intracellular transportGO:19025821660.021
response to nutrient levelsGO:00316673700.021
vesicle localizationGO:0051648330.021
carboxylic acid transportGO:00469421150.021
apoptotic processGO:00069153810.021
alcohol metabolic processGO:0006066770.021
neuromuscular processGO:005090520.021
response to biotic stimulusGO:00096072260.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
positive regulation of synaptic vesicle exocytosisGO:200030230.020
protein oligomerizationGO:00512591910.020
Rat
transcription dna templatedGO:00063513770.020
catabolic processGO:00090563510.020
synaptic transmission glycinergicGO:006001220.020
angiotensin mediated drinking behaviorGO:000305120.020
response to fungicideGO:0060992200.020
cellular ion homeostasisGO:00068731840.020
Rat
endocytosisGO:0006897840.020
multicellular organismal reproductive processGO:00486092330.020
response to external biotic stimulusGO:00432072210.020
pallium developmentGO:0021543420.019
nucleotide metabolic processGO:00091172790.019
smooth muscle contraction involved in micturitionGO:006008310.019
muscle system processGO:00030121150.019
positive regulation of rna biosynthetic processGO:19026801970.019
purine ribonucleoside metabolic processGO:00461281680.018
positive regulation of phosphorylationGO:00423271770.018
circadian rhythmGO:0007623880.018
organonitrogen compound catabolic processGO:19015651790.018
glycosyl compound metabolic processGO:19016571820.018
negative regulation of cellular component organizationGO:0051129830.018
negative regulation of secretionGO:0051048820.018
regulation of catalytic activityGO:00507903040.018
transcription from rna polymerase ii promoterGO:00063662520.018
divalent inorganic cation transportGO:00725111340.018
cellular response to hormone stimulusGO:00328702470.018
regulation of secretion by cellGO:19035302080.017
regulation of nucleic acid templated transcriptionGO:19035063800.017
response to amineGO:0014075460.017
positive regulation of phosphorus metabolic processGO:00105622620.017
regulation of multicellular organismal developmentGO:20000263760.017
brain renin angiotensin systemGO:000203530.017
regulation of cellular amino acid metabolic processGO:000652120.017
regulation of protein metabolic processGO:00512462890.017
camp metabolic processGO:0046058630.017
phospholipid metabolic processGO:0006644610.017
cell morphogenesis involved in differentiationGO:00009041190.017
anatomical structure morphogenesisGO:00096532980.016
Mouse
protein heterooligomerizationGO:0051291890.016
Rat
sodium ion transmembrane transportGO:0035725670.016
Human
carbohydrate derivative catabolic processGO:19011361470.016
positive regulation of cellular component biogenesisGO:0044089550.016
circulatory system processGO:00030131830.016
Rat
cellular nitrogen compound catabolic processGO:00442701630.016
organophosphate biosynthetic processGO:00904071430.016
negative regulation of apoptotic processGO:00430661810.016
response to cytokineGO:00340972150.016
regulation of cellular protein metabolic processGO:00322682670.016
negative regulation of macromolecule metabolic processGO:00106052600.016
negative regulation of cell deathGO:00605482290.016
glandular epithelial cell differentiationGO:000206740.016
cellular macromolecule localizationGO:00707271220.016
positive regulation of catalytic activityGO:00430851840.016
macromolecule localizationGO:00330362520.016
Mouse
inflammatory responseGO:00069541500.016
programmed cell deathGO:00125013920.016
positive regulation of somatostatin secretionGO:009027440.015
monocarboxylic acid metabolic processGO:00327871520.015
protein localizationGO:00081041910.015
Mouse
response to carbohydrateGO:00097431830.015
carboxylic acid biosynthetic processGO:0046394830.015
anion transportGO:00068201780.015
divalent inorganic cation homeostasisGO:00725071650.015
Rat
regulation of insulin secretionGO:0050796650.015
positive regulation of cellular component organizationGO:00511302000.015
potassium ion transmembrane transportGO:0071805710.015
Human Mouse
positive regulation of cellular amine metabolic processGO:003324030.015
cellular modified amino acid metabolic processGO:0006575610.015
positive regulation of neuron differentiationGO:00456661260.015
synaptic vesicle exocytosisGO:0016079150.015
positive regulation of peptide secretionGO:0002793520.015
response to radiationGO:00093141370.015
regulation of metal ion transportGO:00109591180.015
spermatogenesisGO:0007283990.015
nucleoside phosphate catabolic processGO:19012921400.015
motor neuron axon guidanceGO:000804510.015
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.015
response to osmotic stressGO:0006970420.015
response to toxic substanceGO:00096361330.014
male gonad developmentGO:0008584590.014
regulation of apoptotic processGO:00429813350.014
regulation of lipid biosynthetic processGO:0046890380.014
anion transmembrane transportGO:0098656770.014
alternative mrna splicing via spliceosomeGO:000038040.014
calcium ion dependent exocytosis of neurotransmitterGO:004879120.014
male mating behaviorGO:006017930.014
response to oxygen levelsGO:00704822650.014
cytoskeleton organizationGO:00070101110.014
regulation of signal transductionGO:00099663180.014
response to nutrientGO:00075842480.014
cell migrationGO:00164771970.014
regulation of cell proliferationGO:00421273590.014
response to amphetamineGO:0001975250.014
regulation of purine nucleotide metabolic processGO:19005421150.014
positive regulation of cell proliferationGO:00082842490.014
regulation of rna biosynthetic processGO:20011413810.014
somatostatin secretionGO:007025370.013
negative regulation of nervous system developmentGO:0051961790.013
guanosine containing compound metabolic processGO:1901068740.013
phenol containing compound metabolic processGO:0018958300.013
hormone metabolic processGO:0042445690.013
cell cycleGO:00070491010.013
c21 steroid hormone biosynthetic processGO:0006700100.013
regulation of cellular component movementGO:00512701500.013
camp biosynthetic processGO:0006171470.013
tachykinin receptor signaling pathwayGO:000721730.013
cellular response to stressGO:00335542690.013
glial cell differentiationGO:0010001650.013
operant conditioningGO:003510640.013
regenerationGO:00310991630.013
development of primary sexual characteristicsGO:00451371070.013
synaptic vesicle transportGO:0048489230.013
gamete generationGO:00072761240.012
acid secretionGO:0046717480.012
progesterone biosynthetic processGO:000670130.012
positive regulation of cell developmentGO:00107201760.012
ossificationGO:0001503700.012
regulation of neuronal synaptic plasticityGO:0048168310.012
small molecule biosynthetic processGO:00442831240.012
regulation of neuron differentiationGO:00456642080.012
protein transportGO:00150311320.012
retina morphogenesis in camera type eyeGO:006004210.012
Mouse
response to hydrogen peroxideGO:0042542890.012
response to fatty acidGO:0070542650.012
response to oxidative stressGO:00069791860.012
dicarboxylic acid metabolic processGO:0043648420.012
localization of cellGO:00516742020.012
tissue developmentGO:00098882520.012
Mouse
positive regulation of phosphate metabolic processGO:00459372620.012
chemosensory behaviorGO:000763520.012
dicarboxylic acid transportGO:0006835340.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
muscle contractionGO:0006936880.012
regulation of phosphatidylinositol dephosphorylationGO:006030410.012
fractalkine metabolic processGO:005075630.012
regulation of cell cycleGO:0051726730.012
single organism catabolic processGO:00447122830.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
cellular response to organic cyclic compoundGO:00714072020.012
Human Mouse
response to glucocorticoidGO:00513842230.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
olfactory behaviorGO:004204820.012
sodium ion transportGO:0006814820.012
Human
sexual reproductionGO:00199531480.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
male sex differentiationGO:0046661640.012
gliogenesisGO:0042063930.012
actin filament based processGO:0030029860.011
response to corticosteroidGO:00319602350.011
intracellular protein transportGO:0006886790.011
monocarboxylic acid transportGO:0015718520.011
response to mechanical stimulusGO:00096121340.011
protein localization to organelleGO:0033365570.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
response to peptideGO:19016522920.011
negative regulation of signal transductionGO:0009968830.011
response to lipopolysaccharideGO:00324961910.011
response to glucoseGO:00097491360.011
rna biosynthetic processGO:00327743800.011
response to woundingGO:00096112540.011
regulation of protein modification processGO:00313991940.011
endocrine system developmentGO:0035270300.011
purine containing compound catabolic processGO:00725231380.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
signal transduction by phosphorylationGO:00230141440.011
glycerophospholipid metabolic processGO:0006650470.011
fatty acid transportGO:0015908250.011
male gamete generationGO:0048232990.011
cellular response to alcoholGO:0097306870.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
Rat
sulfur compound metabolic processGO:0006790700.011
regulation of cellular catabolic processGO:00313291010.011
response to monosaccharideGO:00342841590.011
visual perceptionGO:000760130.011
response to ketoneGO:19016541820.011
acute inflammatory responseGO:0002526580.011
protein tetramerizationGO:0051262380.010
Rat
response to morphineGO:0043278270.010
vasoconstrictionGO:0042310540.010
positive regulation of hormone secretionGO:0046887650.010
cellular modified amino acid biosynthetic processGO:0042398180.010
metal ion homeostasisGO:00550651860.010
Rat
calcium ion transportGO:00068161310.010
regulation of cellular component biogenesisGO:0044087860.010
lipid modificationGO:0030258520.010
sex differentiationGO:00075481130.010
heart morphogenesisGO:000300730.010
endoplasmic reticulum organizationGO:000702910.010
steroid metabolic processGO:0008202730.010
spinal cord developmentGO:0021510270.010
somatostatin signaling pathwayGO:003817040.010
positive regulation of apoptotic processGO:00430651540.010
generation of ovulation cycle rhythmGO:006011220.010

Hcn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.232
eye diseaseDOID:561400.232
eye and adnexa diseaseDOID:149200.232
nervous system diseaseDOID:86300.232
retinal diseaseDOID:567900.232
sensory system diseaseDOID:005015500.232
retinal degenerationDOID:846600.107
lipid metabolism disorderDOID:314600.040
congenital adrenal hyperplasiaDOID:005081100.040
disease of metabolismDOID:001466700.040
inherited metabolic disorderDOID:65500.040
steroid inherited metabolic disorderDOID:170100.040
retinitis pigmentosaDOID:1058400.020
disease of mental healthDOID:15000.016
substance related disorderDOID:30300.016
substance dependenceDOID:997300.016
cone rod dystrophyDOID:005057200.012