Rattus norvegicus

0 known processes

Idh2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

Idh2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
coenzyme metabolic processGO:0006732860.510
oxoacid metabolic processGO:00434362900.377
Yeast Rat
carboxylic acid metabolic processGO:00197522890.305
Yeast Rat
organic acid metabolic processGO:00060822920.224
Yeast Rat
single organism biosynthetic processGO:00447113420.197
Yeast
nucleoside phosphate metabolic processGO:00067532830.180
nucleotide metabolic processGO:00091172790.165
nucleobase containing small molecule metabolic processGO:00550863160.123
single organism catabolic processGO:00447122830.116
Yeast
cofactor metabolic processGO:0051186950.112
ribose phosphate metabolic processGO:00196932350.096
cellular catabolic processGO:00442482950.091
Yeast
purine nucleotide metabolic processGO:00061632290.086
nucleoside monophosphate metabolic processGO:0009123930.084
macromolecular complex assemblyGO:00650032730.079
organophosphate metabolic processGO:00196373700.079
cellular response to endogenous stimulusGO:00714953770.068
oxidation reduction processGO:00551143040.068
Human Yeast Mouse Rat
carbohydrate derivative metabolic processGO:19011353460.068
protein complex assemblyGO:00064612630.068
programmed cell deathGO:00125013920.066
protein complex biogenesisGO:00702712630.065
response to nutrient levelsGO:00316673700.063
regulation of programmed cell deathGO:00430673410.060
organic substance catabolic processGO:19015753160.060
Yeast
purine ribonucleoside monophosphate metabolic processGO:0009167840.058
amine metabolic processGO:0009308380.057
organonitrogen compound biosynthetic processGO:19015661670.056
Yeast
nucleoside metabolic processGO:00091161790.056
protein complex subunit organizationGO:00718223020.052
regulation of cellular component organizationGO:00511283680.052
regulation of cellular ketone metabolic processGO:0010565270.052
purine nucleoside monophosphate metabolic processGO:0009126840.050
purine ribonucleoside triphosphate metabolic processGO:00092051400.050
purine containing compound metabolic processGO:00725212530.049
cellular component assemblyGO:00226073600.048
catabolic processGO:00090563510.048
Yeast
organonitrogen compound catabolic processGO:19015651790.047
neuron projection developmentGO:00311752730.046
response to decreased oxygen levelsGO:00362932370.045
purine ribonucleoside metabolic processGO:00461281680.045
response to oxygen levelsGO:00704822650.045
cellular response to oxygen containing compoundGO:19017013860.044
ribonucleotide metabolic processGO:00092592310.043
generation of precursor metabolites and energyGO:0006091620.043
ribonucleoside metabolic processGO:00091191740.043
monocarboxylic acid metabolic processGO:00327871520.041
Yeast
purine nucleoside metabolic processGO:00422781690.041
energy derivation by oxidation of organic compoundsGO:0015980460.041
porphyrin containing compound metabolic processGO:000677880.039
anatomical structure morphogenesisGO:00096532980.039
regulation of protein metabolic processGO:00512462890.038
response to nutrientGO:00075842480.038
response to monosaccharideGO:00342841590.036
cellular amine metabolic processGO:0044106380.036
cold acclimationGO:000963110.036
purine nucleoside monophosphate biosynthetic processGO:0009127200.036
macromolecular complex subunit organizationGO:00439333390.035
response to carbohydrateGO:00097431830.033
purine containing compound catabolic processGO:00725231380.033
nicotinamide nucleotide metabolic processGO:0046496280.033
central nervous system developmentGO:00074173110.033
regulation of apoptotic processGO:00429813350.033
cellular chemical homeostasisGO:00550822470.032
heterocycle catabolic processGO:00467001670.032
organelle organizationGO:00069962660.031
nucleoside triphosphate metabolic processGO:00091411440.031
nucleoside triphosphate catabolic processGO:00091431230.030
porphyrin containing compound biosynthetic processGO:000677960.030
reproductive processGO:00224143720.030
Rat
response to reactive oxygen speciesGO:00003021200.030
response to glucoseGO:00097491360.030
nucleoside phosphate catabolic processGO:19012921400.030
regulation of phosphorylationGO:00423252480.030
intracellular signal transductionGO:00355563140.030
protein oligomerizationGO:00512591910.029
response to estrogenGO:00436272320.029
cellular amino acid metabolic processGO:00065201070.029
Yeast
nucleoside monophosphate biosynthetic processGO:0009124280.029
positive regulation of nitrogen compound metabolic processGO:00511733340.029
response to hexoseGO:00097461440.029
head developmentGO:00603222470.029
glycosyl compound metabolic processGO:19016571820.028
lipid metabolic processGO:00066292830.028
Yeast
alpha amino acid catabolic processGO:1901606200.028
tetrapyrrole metabolic processGO:0033013110.028
regulation of cell motilityGO:20001451310.028
positive regulation of cell proliferationGO:00082842490.027
ribonucleoside monophosphate metabolic processGO:0009161880.027
purine ribonucleotide metabolic processGO:00091502270.027
cellular ketone metabolic processGO:0042180510.027
cellular response to stressGO:00335542690.027
response to oxidative stressGO:00069791860.027
cellular response to lipidGO:00713962010.026
purine ribonucleoside triphosphate catabolic processGO:00092071220.026
regulation of cellular amino acid metabolic processGO:000652120.026
response to peptide hormoneGO:00434342780.026
positive regulation of apoptotic processGO:00430651540.026
neuron developmentGO:00486662860.025
apoptotic processGO:00069153810.025
cellular lipid metabolic processGO:00442552080.025
Yeast
response to hypoxiaGO:00016662310.025
negative regulation of cell deathGO:00605482290.024
brain developmentGO:00074202470.024
response to acid chemicalGO:00011012220.024
cellular response to nitrogen compoundGO:19016992100.024
cytoskeleton organizationGO:00070101110.024
cell projection organizationGO:00300303020.024
cellular homeostasisGO:00197252520.023
purine nucleoside catabolic processGO:00061521240.023
positive regulation of cell deathGO:00109421840.023
positive regulation of cellular component organizationGO:00511302000.023
positive regulation of signalingGO:00230562700.023
regulation of nervous system developmentGO:00519602640.023
atp catabolic processGO:0006200540.023
purine ribonucleotide catabolic processGO:00091541360.023
regulation of phosphorus metabolic processGO:00511743490.022
response to external biotic stimulusGO:00432072210.022
cellular response to hormone stimulusGO:00328702470.022
regulation of multicellular organismal developmentGO:20000263760.022
carbohydrate derivative catabolic processGO:19011361470.022
positive regulation of developmental processGO:00510942830.022
cellular component biogenesisGO:00440853680.022
positive regulation of multicellular organismal processGO:00512403870.021
neuron differentiationGO:00301823680.021
single organism intracellular transportGO:19025821660.021
response to inorganic substanceGO:00100353770.021
protein homooligomerizationGO:0051260910.021
purine ribonucleoside diphosphate biosynthetic processGO:000918090.021
negative regulation of response to stimulusGO:00485851550.021
chromosome segregationGO:000705920.021
nucleoside catabolic processGO:00091641260.021
cellular component movementGO:00069282480.020
organic acid catabolic processGO:0016054490.020
Yeast
organic acid biosynthetic processGO:0016053830.020
Yeast
response to peptideGO:19016522920.020
pyridine containing compound metabolic processGO:0072524320.020
regulation of cellular amine metabolic processGO:003323880.020
chemical homeostasisGO:00488782920.020
glycosyl compound catabolic processGO:19016581260.020
peptidyl amino acid modificationGO:00181931260.019
cellular response to organonitrogen compoundGO:00714171970.019
regulation of cell differentiationGO:00455953200.019
nucleotide catabolic processGO:00091661390.019
organophosphate catabolic processGO:00464341480.019
response to extracellular stimulusGO:00099913800.019
regulation of cell developmentGO:00602842630.018
ribonucleoside triphosphate metabolic processGO:00091991410.018
cellular nitrogen compound catabolic processGO:00442701630.018
nitrogen compound transportGO:00717052290.018
organic cyclic compound catabolic processGO:19013611750.018
positive regulation of programmed cell deathGO:00430681570.018
growthGO:00400071650.018
circulatory system developmentGO:00723591340.017
glycogen metabolic processGO:0005977230.017
regulation of hormone levelsGO:00108171870.017
atp metabolic processGO:0046034720.017
aromatic compound catabolic processGO:00194391680.017
response to glucocorticoidGO:00513842230.017
negative regulation of apoptotic processGO:00430661810.017
negative regulation of signalingGO:00230571570.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
regulation of protein modification processGO:00313991940.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
regulation of signal transductionGO:00099663180.017
positive regulation of cell communicationGO:00106472710.016
activation of cysteine type endopeptidase activityGO:009720240.016
ribonucleotide catabolic processGO:00092611360.016
response to corticosteroidGO:00319602350.016
ion transmembrane transportGO:00342203650.016
carboxylic acid catabolic processGO:0046395490.016
Yeast
regulation of cellular protein metabolic processGO:00322682670.016
negative regulation of metabolic processGO:00098923310.016
positive regulation of cellular protein metabolic processGO:00322701670.016
cellular response to organic cyclic compoundGO:00714072020.016
intracellular transportGO:00469071850.015
positive regulation of response to stimulusGO:00485842850.015
positive regulation of neurogenesisGO:00507691650.015
cellular polysaccharide metabolic processGO:0044264230.015
cell cycleGO:00070491010.015
polysaccharide metabolic processGO:0005976250.015
carbohydrate derivative biosynthetic processGO:19011371240.015
regulation of phosphate metabolic processGO:00192203490.015
response to other organismGO:00517072200.015
regulation of intracellular signal transductionGO:19025312180.015
locomotionGO:00400112370.015
protein phosphorylationGO:00064683450.015
positive regulation of cell differentiationGO:00455972170.015
purine ribonucleoside monophosphate catabolic processGO:0009169550.014
regulation of cell projection organizationGO:00313441750.014
cation homeostasisGO:00550801950.014
positive regulation of cellular biosynthetic processGO:00313282950.014
purine nucleotide catabolic processGO:00061951360.014
positive regulation of transportGO:00510502450.014
positive regulation of neuron projection developmentGO:0010976990.014
hormone secretionGO:00468791150.014
positive regulation of protein metabolic processGO:00512471780.014
regulation of cell proliferationGO:00421273590.014
regulation of response to stressGO:00801341260.014
negative regulation of macromolecule metabolic processGO:00106052600.014
ras protein signal transductionGO:0007265290.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
agingGO:00075682410.014
cellular ion homeostasisGO:00068731840.014
organophosphate biosynthetic processGO:00904071430.014
cell migrationGO:00164771970.014
negative regulation of cell communicationGO:00106481580.013
cation transportGO:00068123820.013
positive regulation of molecular functionGO:00440932300.013
protein localizationGO:00081041910.013
cell cell signalingGO:00072673350.013
response to ionizing radiationGO:0010212590.013
regulation of protein phosphorylationGO:00019321830.013
rna metabolic processGO:00160704060.013
glutamine family amino acid metabolic processGO:0009064150.013
Yeast
negative regulation of cellular metabolic processGO:00313242810.013
cellular cation homeostasisGO:00300031800.013
heme biosynthetic processGO:000678340.013
ribonucleoside catabolic processGO:00424541260.013
homeostatic processGO:00425923310.013
regulation of molecular functionGO:00650093980.013
nucleoside phosphate biosynthetic processGO:19012931020.013
macromolecule localizationGO:00330362520.013
regulation of neurogenesisGO:00507672470.013
cellular metal ion homeostasisGO:00068751720.013
ion homeostasisGO:00508012120.013
cytoplasmic transportGO:00164821150.012
regulation of neuron differentiationGO:00456642080.012
cellular amino acid catabolic processGO:0009063210.012
nad metabolic processGO:0019674150.012
purine nucleoside monophosphate catabolic processGO:0009128550.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
nucleotide biosynthetic processGO:0009165980.012
response to biotic stimulusGO:00096072260.012
regulation of neuron projection developmentGO:00109751610.012
response to purine containing compoundGO:00140741260.012
response to ethanolGO:00454711620.012
response to campGO:0051591910.012
regulation of cellular localizationGO:00603412630.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
multicellular organismal reproductive processGO:00486092330.012
cellular carbohydrate metabolic processGO:0044262720.011
embryonic pattern specificationGO:000988010.011
positive regulation of nervous system developmentGO:00519621780.011
nucleoside monophosphate catabolic processGO:0009125560.011
carboxylic acid biosynthetic processGO:0046394830.011
Yeast
negative regulation of signal transductionGO:0009968830.011
secretionGO:00469033070.011
positive regulation of rna metabolic processGO:00512542030.011
reproductionGO:00000032450.011
heart morphogenesisGO:000300730.011
single organism organelle organizationGO:19025891800.011
response to cytokineGO:00340972150.011
reproductive system developmentGO:00614581280.011
Rat
cellular glucan metabolic processGO:0006073230.011
actin filament based processGO:0030029860.011
sulfur compound metabolic processGO:0006790700.011
regulation of ion transportGO:00432692450.011
hepaticobiliary system developmentGO:0061008900.011
gland developmentGO:00487321550.011
purine nucleoside triphosphate catabolic processGO:00091461220.010
response to hydrogen peroxideGO:0042542890.010
response to vitaminGO:00332731310.010
response to temperature stimulusGO:0009266940.010
ribonucleotide biosynthetic processGO:0009260850.010
positive regulation of phosphate metabolic processGO:00459372620.010
cellular response to extracellular stimulusGO:0031668730.010
cellular response to oxidative stressGO:0034599760.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
positive regulation of cell projection organizationGO:00313461110.010
syncytium formationGO:000694940.010

Idh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.037
Human
disease of metabolismDOID:001466700.037
Human
amino acid metabolic disorderDOID:925200.025
Human