Rattus norvegicus

0 known processes

Ptpn22

protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

(Aliases: Ptpn8)

Ptpn22 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of signal transductionGO:00099663180.119
Human
positive regulation of response to stimulusGO:00485842850.106
Human
organic substance catabolic processGO:19015753160.089
cellular component movementGO:00069282480.084
positive regulation of immune system processGO:0002684900.084
Human
catabolic processGO:00090563510.082
cell activationGO:0001775970.072
Human
organic acid metabolic processGO:00060822920.071
regulation of multicellular organismal developmentGO:20000263760.070
cellular catabolic processGO:00442482950.068
response to woundingGO:00096112540.067
Rat
immune system processGO:00023762040.067
Human
immune responseGO:00069551040.065
response to extracellular stimulusGO:00099913800.063
regulation of immune system processGO:00026821230.062
Human
cellular component biogenesisGO:00440853680.062
negative regulation of natural killer cell mediated immunityGO:000271640.061
oxoacid metabolic processGO:00434362900.060
regulation of protein metabolic processGO:00512462890.060
carboxylic acid metabolic processGO:00197522890.059
positive regulation of multicellular organismal processGO:00512403870.058
macromolecular complex subunit organizationGO:00439333390.057
homeostatic processGO:00425923310.056
intracellular signal transductionGO:00355563140.056
response to nutrient levelsGO:00316673700.056
positive regulation of nitrogen compound metabolic processGO:00511733340.056
cellular component assemblyGO:00226073600.054
reproductive processGO:00224143720.053
negative regulation of innate immune responseGO:004582440.053
positive regulation of biosynthetic processGO:00098913190.051
regulation of cell proliferationGO:00421273590.051
Human
localization of cellGO:00516742020.051
programmed cell deathGO:00125013920.051
regulation of cell differentiationGO:00455953200.050
cellular amino acid metabolic processGO:00065201070.049
cell type specific apoptotic processGO:00972851340.049
response to biotic stimulusGO:00096072260.048
response to peptide hormoneGO:00434342780.046
amine metabolic processGO:0009308380.046
protein complex subunit organizationGO:00718223020.046
cellular response to stressGO:00335542690.046
cellular amine metabolic processGO:0044106380.044
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.044
response to inorganic substanceGO:00100353770.044
positive regulation of developmental processGO:00510942830.043
negative regulation of response to stimulusGO:00485851550.043
Human
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.043
neuron differentiationGO:00301823680.042
organophosphate metabolic processGO:00196373700.042
defense responseGO:00069521940.042
protein phosphorylationGO:00064683450.041
lipid metabolic processGO:00066292830.041
wound healingGO:00420601220.040
Rat
positive regulation of intracellular signal transductionGO:19025331380.040
regulation of molecular functionGO:00650093980.040
single organism catabolic processGO:00447122830.040
regulation of cellular component organizationGO:00511283680.040
regulation of intracellular signal transductionGO:19025312180.039
organonitrogen compound catabolic processGO:19015651790.039
regulation of programmed cell deathGO:00430673410.038
leukocyte activationGO:0045321760.038
Human
regulation of cellular ketone metabolic processGO:0010565270.038
agingGO:00075682410.038
response to radiationGO:00093141370.037
protein complex assemblyGO:00064612630.037
nucleobase containing small molecule metabolic processGO:00550863160.037
regulation of phosphorus metabolic processGO:00511743490.037
regulation of cellular amino acid metabolic processGO:000652120.037
positive regulation of phosphorus metabolic processGO:00105622620.037
positive regulation of transportGO:00510502450.037
regulation of phosphate metabolic processGO:00192203490.036
natural killer cell mediated immune response to tumor cellGO:000242310.036
cell migrationGO:00164771970.036
regulation of cellular amine metabolic processGO:003323880.036
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.036
macromolecular complex assemblyGO:00650032730.036
regulation of cellular protein metabolic processGO:00322682670.035
regenerationGO:00310991630.035
Rat
regulation of cellular localizationGO:00603412630.035
negative regulation of immune response to tumor cellGO:000283820.034
response to oxygen levelsGO:00704822650.034
regulation of locomotionGO:00400121480.034
cellular ketone metabolic processGO:0042180510.034
response to oxidative stressGO:00069791860.033
organelle organizationGO:00069962660.033
positive regulation of phosphate metabolic processGO:00459372620.032
nucleoside phosphate metabolic processGO:00067532830.032
rna biosynthetic processGO:00327743800.032
response to tumor cellGO:000234740.032
blood circulationGO:00080151830.032
cell projection organizationGO:00300303020.032
cellular chemical homeostasisGO:00550822470.032
inflammatory responseGO:00069541500.032
cellular homeostasisGO:00197252520.031
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.031
cellular response to oxygen containing compoundGO:19017013860.031
purine containing compound metabolic processGO:00725212530.031
positive regulation of cell proliferationGO:00082842490.031
positive regulation of cellular biosynthetic processGO:00313282950.031
cellular lipid metabolic processGO:00442552080.030
lymphocyte activationGO:0046649430.030
Human
positive regulation of cell differentiationGO:00455972170.030
response to growth factorGO:00708481890.030
positive regulation of macromolecule biosynthetic processGO:00105572470.030
response to external biotic stimulusGO:00432072210.029
macromolecule localizationGO:00330362520.029
response to estrogenGO:00436272320.029
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.029
carbohydrate derivative metabolic processGO:19011353460.029
vesicle mediated transportGO:00161921810.029
nucleotide metabolic processGO:00091172790.029
negative regulation of response to tumor cellGO:000283520.028
single organism reproductive processGO:00447022970.028
positive regulation of cell communicationGO:00106472710.028
regulation of cell developmentGO:00602842630.028
positive regulation of gene expressionGO:00106282440.028
regulation of phosphorylationGO:00423252480.028
biological adhesionGO:00226101100.028
neuron developmentGO:00486662860.028
cell motilityGO:00488702020.028
apoptotic processGO:00069153810.028
reproductionGO:00000032450.027
single organism organelle organizationGO:19025891800.027
single organism biosynthetic processGO:00447113420.026
heterocycle catabolic processGO:00467001670.026
central nervous system developmentGO:00074173110.026
organic cyclic compound catabolic processGO:19013611750.026
small gtpase mediated signal transductionGO:0007264360.026
organophosphate catabolic processGO:00464341480.026
response to metal ionGO:00100382530.026
regulation of secretionGO:00510462240.026
rna metabolic processGO:00160704060.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
protein oligomerizationGO:00512591910.026
regulation of response to stressGO:00801341260.025
regulation of protein phosphorylationGO:00019321830.025
response to molecule of bacterial originGO:00022371940.025
circulatory system processGO:00030131830.025
response to cytokineGO:00340972150.025
regulation of immune response to tumor cellGO:000283730.025
neuron deathGO:00709971270.025
response to acid chemicalGO:00011012220.025
regulation of hormone levelsGO:00108171870.025
multi organism reproductive processGO:00447032620.024
positive regulation of signalingGO:00230562700.024
chemical homeostasisGO:00488782920.024
neuron projection developmentGO:00311752730.024
aromatic compound catabolic processGO:00194391680.024
ras protein signal transductionGO:0007265290.024
cell adhesionGO:00071551100.024
cardiovascular system developmentGO:00723581340.024
regulation of neuron deathGO:19012141150.024
purine ribonucleotide metabolic processGO:00091502270.024
protein complex biogenesisGO:00702712630.023
regulation of cell migrationGO:00303341280.023
anatomical structure morphogenesisGO:00096532980.023
multicellular organism reproductionGO:00325042330.023
response to decreased oxygen levelsGO:00362932370.023
response to other organismGO:00517072200.023
nucleoside metabolic processGO:00091161790.023
nucleobase containing compound catabolic processGO:00346551520.023
antigen receptor mediated signaling pathwayGO:005085110.023
Human
cellular nitrogen compound catabolic processGO:00442701630.023
multicellular organismal reproductive processGO:00486092330.022
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.022
secretion by cellGO:00329402480.022
positive regulation of neurogenesisGO:00507691650.022
regulation of protein modification processGO:00313991940.022
purine ribonucleoside metabolic processGO:00461281680.022
cellular response to organic cyclic compoundGO:00714072020.022
positive regulation of cellular amino acid metabolic processGO:004576410.022
protein localizationGO:00081041910.022
negative regulation of signalingGO:00230571570.022
Human
cellular response to endogenous stimulusGO:00714953770.022
positive regulation of programmed cell deathGO:00430681570.022
nucleoside phosphate catabolic processGO:19012921400.022
brain developmentGO:00074202470.021
response to carbohydrateGO:00097431830.021
response to lipopolysaccharideGO:00324961910.021
secretionGO:00469033070.021
regulation of apoptotic processGO:00429813350.021
locomotionGO:00400112370.021
regulation of cellular component movementGO:00512701500.021
immune response to tumor cellGO:000241830.021
ribonucleotide metabolic processGO:00092592310.021
cellular metal ion homeostasisGO:00068751720.021
response to corticosteroidGO:00319602350.021
negative regulation of cell deathGO:00605482290.021
regulation of transcription dna templatedGO:00063553740.021
positive regulation of cell deathGO:00109421840.021
response to peptideGO:19016522920.020
positive regulation of signal transductionGO:00099671750.020
response to ketoneGO:19016541820.020
nucleoside triphosphate metabolic processGO:00091411440.020
circulatory system developmentGO:00723591340.020
regulation of cell motilityGO:20001451310.020
negative regulation of biosynthetic processGO:00098901680.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
response to reactive oxygen speciesGO:00003021200.020
positive regulation of cellular amine metabolic processGO:003324030.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
regulation of rna biosynthetic processGO:20011413810.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
purine nucleotide metabolic processGO:00061632290.020
glycosyl compound metabolic processGO:19016571820.020
negative regulation of cell communicationGO:00106481580.019
Human
intracellular transportGO:00469071850.019
negative regulation of metabolic processGO:00098923310.019
negative regulation of macromolecule metabolic processGO:00106052600.019
leukocyte differentiationGO:0002521300.019
positive regulation of protein modification processGO:00314011420.019
regulation of neurogenesisGO:00507672470.019
transcription dna templatedGO:00063513770.019
ribonucleoside triphosphate metabolic processGO:00091991410.019
tissue developmentGO:00098882520.019
Rat
ribose phosphate metabolic processGO:00196932350.019
ribonucleoside metabolic processGO:00091191740.019
response to monosaccharideGO:00342841590.019
positive regulation of molecular functionGO:00440932300.019
regulation of neuron apoptotic processGO:0043523830.019
regulation of cell projection organizationGO:00313441750.019
response to hypoxiaGO:00016662310.019
positive regulation of immune responseGO:0050778420.019
Human
nucleotide catabolic processGO:00091661390.019
regulation of protein kinase activityGO:00458591050.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
cation homeostasisGO:00550801950.018
positive regulation of cellular protein metabolic processGO:00322701670.018
purine containing compound catabolic processGO:00725231380.018
regulation of rna metabolic processGO:00512523910.018
gastrulationGO:000736920.018
transcription from rna polymerase ii promoterGO:00063662520.018
regulation of nervous system developmentGO:00519602640.018
purine nucleoside metabolic processGO:00422781690.018
regulation of immune responseGO:0050776550.018
Human
divalent inorganic cation homeostasisGO:00725071650.017
purine nucleotide catabolic processGO:00061951360.017
endocytosisGO:0006897840.017
positive regulation of cellular component organizationGO:00511302000.017
carbohydrate derivative catabolic processGO:19011361470.017
positive regulation of locomotionGO:00400171020.017
regulation of neuron projection developmentGO:00109751610.017
protein heterooligomerizationGO:0051291890.017
metal ion transportGO:00300012890.017
response to ethanolGO:00454711620.017
regulation of defense responseGO:0031347680.017
t cell receptor signaling pathwayGO:005085210.017
Human
negative regulation of immune system processGO:0002683390.017
Human
purine nucleoside triphosphate metabolic processGO:00091441410.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
positive regulation of protein metabolic processGO:00512471780.017
cellular response to growth factor stimulusGO:00713631620.017
organic hydroxy compound metabolic processGO:19016151150.017
response to nutrientGO:00075842480.017
response to estradiolGO:00323551640.017
negative regulation of multicellular organismal processGO:00512412030.017
positive regulation of rna metabolic processGO:00512542030.017
single organism intracellular transportGO:19025821660.017
negative regulation of cellular metabolic processGO:00313242810.017
positive regulation of apoptotic processGO:00430651540.016
metal ion homeostasisGO:00550651860.016
regulation of response to tumor cellGO:000283430.016
negative regulation of apoptotic processGO:00430661810.016
nitrogen compound transportGO:00717052290.016
nucleic acid templated transcriptionGO:00976593790.016
innate immune responseGO:0045087350.016
positive regulation of phosphorylationGO:00423271770.016
cellular response to hormone stimulusGO:00328702470.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
positive regulation of rna biosynthetic processGO:19026801970.016
axis specificationGO:000979840.016
nucleoside triphosphate catabolic processGO:00091431230.016
response to bacteriumGO:00096172000.016
cellular component morphogenesisGO:00329891550.016
transmembrane transportGO:00550854120.016
regulation of catalytic activityGO:00507903040.016
regulation of secretion by cellGO:19035302080.016
negative regulation of gene expressionGO:00106291990.016
response to toxic substanceGO:00096361330.016
proteolysisGO:00065081750.016
regulation of anatomical structure morphogenesisGO:00226031410.016
anterior posterior pattern specificationGO:000995210.016
actin filament based processGO:0030029860.015
positive regulation of catalytic activityGO:00430851840.015
regulation of neuron differentiationGO:00456642080.015
peptidyl tyrosine phosphorylationGO:0018108720.015
purine ribonucleotide catabolic processGO:00091541360.015
cell morphogenesisGO:00009021420.015
response to insulinGO:00328681330.015
purine nucleoside catabolic processGO:00061521240.015
g protein coupled receptor signaling pathwayGO:00071862420.015
purine ribonucleoside catabolic processGO:00461301240.015
sexual reproductionGO:00199531480.015
vasculature developmentGO:0001944700.015
positive regulation of cell developmentGO:00107201760.015
ribonucleoside catabolic processGO:00424541260.015
head developmentGO:00603222470.015
growthGO:00400071650.015
Rat
cellular cation homeostasisGO:00300031800.015
cellular response to steroid hormone stimulusGO:0071383930.015
cytoskeleton organizationGO:00070101110.015
regulation of system processGO:00440572080.015
positive regulation of cell motilityGO:2000147970.015
behaviorGO:00076102050.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
positive regulation of protein phosphorylationGO:00019341350.015
regulation of hydrolase activityGO:00513361430.015
cellular ion homeostasisGO:00068731840.014
immune effector processGO:0002252530.014
cell chemotaxisGO:0060326310.014
chromosome segregationGO:000705920.014
response to glucoseGO:00097491360.014
positive regulation of cell migrationGO:0030335960.014
cellular response to nitrogen compoundGO:19016992100.014
immune system developmentGO:0002520410.014
response to organophosphorusGO:00466831020.014
ion homeostasisGO:00508012120.014
eye morphogenesisGO:004859240.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
neuron apoptotic processGO:0051402880.014
cation transportGO:00068123820.013
nucleoside catabolic processGO:00091641260.013
response to purine containing compoundGO:00140741260.013
response to vitaminGO:00332731310.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
glycosyl compound catabolic processGO:19016581260.013
negative regulation of transportGO:00510511360.013
regulation of transferase activityGO:00513381230.013
regulation of membrane potentialGO:00423911100.013
epithelium developmentGO:0060429960.013
regulation of catabolic processGO:00098941130.013
organ regenerationGO:00311001010.013
negative regulation of programmed cell deathGO:00430691830.013
establishment of protein localizationGO:00451841410.013
ribonucleotide catabolic processGO:00092611360.013
cellular response to organonitrogen compoundGO:00714171970.013
calcium ion homeostasisGO:00550741620.013
actin cytoskeleton organizationGO:0030036730.013
organophosphate biosynthetic processGO:00904071430.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
regulation of leukocyte activationGO:0002694450.013
Human
reproductive structure developmentGO:00486081280.013
regulation of body fluid levelsGO:0050878900.013
regulation of kinase activityGO:00435491170.013
ribonucleoside triphosphate catabolic processGO:00092031220.012
response to hydrogen peroxideGO:0042542890.012
developmental process involved in reproductionGO:00030061590.012
positive regulation of natural killer cell mediated cytotoxicityGO:004595420.012
cellular response to oxidative stressGO:0034599760.012
t cell activationGO:0042110290.012
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
gamete generationGO:00072761240.012
cellular calcium ion homeostasisGO:00068741600.012
positive regulation of transcription dna templatedGO:00458931970.012
spindle organizationGO:000705120.012
regulation of ion transportGO:00432692450.012
negative regulation of signal transductionGO:0009968830.012
Human
blood vessel developmentGO:0001568690.012
multicellular organism growthGO:003526410.012
lymphocyte homeostasisGO:000226020.012
regulation of response to woundingGO:1903034690.012
cell cycleGO:00070491010.012
regulation of innate immune responseGO:0045088150.012
hormone secretionGO:00468791150.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
peptidyl amino acid modificationGO:00181931260.012
response to mechanical stimulusGO:00096121340.012
monocarboxylic acid metabolic processGO:00327871520.012
peptidyl tyrosine modificationGO:0018212720.012
regulation of leukocyte differentiationGO:1902105200.012
positive regulation of defense responseGO:0031349370.011
positive regulation of neuron differentiationGO:00456661260.011
negative regulation of cellular protein metabolic processGO:00322691060.011
neurological system processGO:00508772190.011
protein homooligomerizationGO:0051260910.011
regulation of cell killingGO:0031341120.011
regulation of anatomical structure sizeGO:00900661350.011
angiogenesisGO:0001525530.011
synaptic growth at neuromuscular junctionGO:005112410.011
positive regulation of nervous system developmentGO:00519621780.011
lipid storageGO:001991510.011
regulation of mapk cascadeGO:00434081160.011
cellular response to lipidGO:00713962010.011
positive regulation of protein kinase activityGO:0045860730.011
mapk cascadeGO:00001651400.011
organonitrogen compound biosynthetic processGO:19015661670.011
positive regulation of cell projection organizationGO:00313461110.011
calcium ion transportGO:00068161310.011
response to alkaloidGO:00432791320.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
reactive oxygen species biosynthetic processGO:190340980.011
ion transmembrane transportGO:00342203650.011
divalent metal ion transportGO:00708381320.011
response to hexoseGO:00097461440.011
gliogenesisGO:0042063930.011
positive regulation of cellular component movementGO:00512721020.011
cytoplasmic transportGO:00164821150.011
anion transportGO:00068201780.011
regulation of smooth muscle cell proliferationGO:0048660750.011
liver developmentGO:0001889900.011
positive regulation of leukocyte activationGO:0002696300.011
spermatogenesisGO:0007283990.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
urogenital system developmentGO:0001655780.011
cellular response to extracellular stimulusGO:0031668730.011
positive regulation of lipid kinase activityGO:009021820.011
tissue regenerationGO:0042246360.011
Rat
response to starvationGO:0042594590.011
alcohol metabolic processGO:0006066770.011
response to transition metal nanoparticleGO:19902671220.011
cell cell signalingGO:00072673350.010
negative regulation of response to biotic stimulusGO:000283240.010
lymphocyte mediated immunityGO:0002449140.010
cellular response to cytokine stimulusGO:00713451270.010
single organismal cell cell adhesionGO:0016337420.010
negative regulation of molecular functionGO:00440921330.010
negative regulation of protein metabolic processGO:00512481140.010
sequestering of metal ionGO:005123890.010
response to glucocorticoidGO:00513842230.010
regulation of cellular catabolic processGO:00313291010.010
embryonic pattern specificationGO:000988010.010
negative regulation of cell proliferationGO:00082851190.010
divalent inorganic cation transportGO:00725111340.010
membrane organizationGO:0061024940.010
regulation of cellular component biogenesisGO:0044087860.010
male gamete generationGO:0048232990.010
regulation of response to external stimulusGO:00321011060.010
reactive oxygen species metabolic processGO:0072593370.010
leukocyte cell cell adhesionGO:000715940.010

Ptpn22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.011
Human
disease of anatomical entityDOID:700.011
Human