Rattus norvegicus

174 known processes

Slc9a1

solute carrier family 9 (sodium/hydrogen exchanger), member 1

(Aliases: Nhe1)

Slc9a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein phosphorylationGO:00064683450.539
regulation of intracellular signal transductionGO:19025312180.398
cellular response to organonitrogen compoundGO:00714171970.393
regulation of signal transductionGO:00099663180.343
regulation of synaptic transmissionGO:00508041410.338
vesicle mediated transportGO:00161921810.323
Rat
positive regulation of phosphorus metabolic processGO:00105622620.296
regulation of catalytic activityGO:00507903040.295
intracellular signal transductionGO:00355563140.274
interleukin 18 productionGO:003262110.265
anatomical structure morphogenesisGO:00096532980.221
positive regulation of catalytic activityGO:00430851840.204
cellular metal ion homeostasisGO:00068751720.201
tissue developmentGO:00098882520.189
neuron differentiationGO:00301823680.182
synaptic transmissionGO:00072682350.181
inflammatory responseGO:00069541500.180
organelle organizationGO:00069962660.176
choline transportGO:001587140.175
growthGO:00400071650.173
cation homeostasisGO:00550801950.164
regulation of phosphorus metabolic processGO:00511743490.164
regulation of neurogenesisGO:00507672470.164
regulation of cellular component organizationGO:00511283680.159
regulation of phosphate metabolic processGO:00192203490.157
positive regulation of signalingGO:00230562700.154
biological adhesionGO:00226101100.154
neuron developmentGO:00486662860.149
single organism organelle organizationGO:19025891800.137
ion homeostasisGO:00508012120.136
organic acid transportGO:00158491160.132
positive regulation of response to stimulusGO:00485842850.126
positive regulation of signal transductionGO:00099671750.125
positive regulation of cell communicationGO:00106472710.123
regulation of neuron differentiationGO:00456642080.119
regulation of kinase activityGO:00435491170.119
regulation of neurotransmitter secretionGO:0046928190.118
regulation of protein modification processGO:00313991940.114
cell cell signalingGO:00072673350.109
regulation of protein phosphorylationGO:00019321830.107
regulation of phosphorylationGO:00423252480.106
signal transduction by phosphorylationGO:00230141440.106
regulation of protein kinase activityGO:00458591050.103
mapk cascadeGO:00001651400.103
monocarboxylic acid transportGO:0015718520.100
regulation of organ formationGO:000315620.098
positive regulation of cell motilityGO:2000147970.097
neuron projection developmentGO:00311752730.096
cell morphogenesisGO:00009021420.095
negative regulation of protein phosphorylationGO:0001933440.094
regulation of multicellular organismal developmentGO:20000263760.090
divalent inorganic cation homeostasisGO:00725071650.090
cellular component assemblyGO:00226073600.089
exocytosisGO:0006887600.088
single organism reproductive processGO:00447022970.087
positive regulation of protein kinase activityGO:0045860730.086
positive regulation of cellular component organizationGO:00511302000.086
regulation of cell developmentGO:00602842630.084
cellular chemical homeostasisGO:00550822470.083
chemical homeostasisGO:00488782920.082
lipid metabolic processGO:00066292830.082
reproductive processGO:00224143720.080
agingGO:00075682410.079
protein autophosphorylationGO:0046777660.078
cellular calcium ion homeostasisGO:00068741600.077
regulation of molecular functionGO:00650093980.077
secretionGO:00469033070.076
positive regulation of cellular protein metabolic processGO:00322701670.076
negative regulation of phosphate metabolic processGO:0045936800.074
enzyme linked receptor protein signaling pathwayGO:00071671160.074
regulation of ion transportGO:00432692450.074
Rat
regulation of mapk cascadeGO:00434081160.073
positive regulation of phosphorylationGO:00423271770.073
cellular response to endogenous stimulusGO:00714953770.072
regulation of cellular protein metabolic processGO:00322682670.071
cation transportGO:00068123820.071
regulation of nervous system developmentGO:00519602640.071
actin filament based processGO:0030029860.070
locomotionGO:00400112370.070
negative regulation of nervous system developmentGO:0051961790.069
appendage morphogenesisGO:003510740.069
regulation of secretion by cellGO:19035302080.069
organophosphate metabolic processGO:00196373700.067
negative regulation of neurogenesisGO:0050768780.067
positive regulation of neurogenesisGO:00507691650.066
carboxylic acid transportGO:00469421150.065
sensory perception of painGO:0019233730.064
regulation of transferase activityGO:00513381230.064
cellular amino acid metabolic processGO:00065201070.063
positive regulation of phosphate metabolic processGO:00459372620.063
ion transmembrane transportGO:00342203650.063
chemosensory behaviorGO:000763520.062
positive regulation of molecular functionGO:00440932300.061
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.061
regulation of cell projection organizationGO:00313441750.061
response to oxygen levelsGO:00704822650.060
cellular component biogenesisGO:00440853680.060
positive regulation of kinase activityGO:0033674770.060
cellular response to organic cyclic compoundGO:00714072020.059
cell adhesionGO:00071551100.058
heart processGO:0003015570.058
positive regulation of mapk cascadeGO:0043410920.057
positive regulation of transferase activityGO:0051347810.056
blood circulationGO:00080151830.056
protein transportGO:00150311320.055
nucleotide biosynthetic processGO:0009165980.055
programmed cell deathGO:00125013920.055
regulation of anatomical structure sizeGO:00900661350.054
mast cell degranulationGO:0043303100.054
neuron deathGO:00709971270.054
establishment of tissue polarityGO:000716420.053
regulation of activation of jak2 kinase activityGO:001053410.053
carbohydrate derivative biosynthetic processGO:19011371240.053
regulation of cell proliferationGO:00421273590.052
regulation of vesicle mediated transportGO:0060627810.052
cellular ion homeostasisGO:00068731840.052
metal ion transportGO:00300012890.051
phenol containing compound metabolic processGO:0018958300.051
apoptotic processGO:00069153810.051
protein complex assemblyGO:00064612630.049
positive regulation of developmental processGO:00510942830.048
localization of cellGO:00516742020.048
response to extracellular stimulusGO:00099913800.048
activation of jak2 kinase activityGO:004297720.048
regulation of protein metabolic processGO:00512462890.048
synapse organizationGO:0050808460.047
response to nutrient levelsGO:00316673700.047
fatty acid transportGO:0015908250.047
regulation of cell differentiationGO:00455953200.046
activation of protein kinase activityGO:0032147470.046
regulation of chronic inflammatory responseGO:000267630.045
cellular response to nitrogen compoundGO:19016992100.045
cytoskeleton organizationGO:00070101110.045
prostate gland morphogenesisGO:006051220.045
amine metabolic processGO:0009308380.045
regulation of blood circulationGO:19035221100.044
reproductionGO:00000032450.044
ras protein signal transductionGO:0007265290.044
positive regulation of intracellular signal transductionGO:19025331380.044
vascular process in circulatory systemGO:0003018960.044
single organism membrane organizationGO:0044802740.044
positive regulation of multicellular organismal processGO:00512403870.044
regulation of cellular amine metabolic processGO:003323880.044
response to woundingGO:00096112540.043
cytokine mediated signaling pathwayGO:0019221430.043
regulation of neuron projection developmentGO:00109751610.043
small gtpase mediated signal transductionGO:0007264360.042
calcium ion homeostasisGO:00550741620.042
learning or memoryGO:0007611900.042
homeostatic processGO:00425923310.042
negative regulation of cell developmentGO:0010721820.041
response to nutrientGO:00075842480.041
positive regulation of protein phosphorylationGO:00019341350.041
multicellular organismal reproductive processGO:00486092330.041
neurotransmitter transportGO:0006836420.040
negative regulation of phosphorus metabolic processGO:0010563800.039
receptor mediated endocytosisGO:0006898420.039
Rat
nucleic acid templated transcriptionGO:00976593790.039
regulation of apoptotic processGO:00429813350.039
negative regulation of cell deathGO:00605482290.039
tube developmentGO:0035295890.039
positive regulation of protein modification processGO:00314011420.038
regulation of circadian sleep wake cycle sleepGO:0045187180.038
defense responseGO:00069521940.038
cell projection organizationGO:00300303020.037
cellular response to peptide hormone stimulusGO:00713751200.037
action potentialGO:0001508540.037
positive regulation of cell developmentGO:00107201760.037
anion transportGO:00068201780.037
regulation of blood vessel sizeGO:0050880890.037
neuron apoptotic processGO:0051402880.037
protein complex subunit organizationGO:00718223020.036
positive regulation of nervous system developmentGO:00519621780.036
macromolecular complex subunit organizationGO:00439333390.036
positive regulation of nucleobase containing compound metabolic processGO:00459353190.036
response to hypoxiaGO:00016662310.036
circulatory system processGO:00030131830.036
positive regulation of secretion by cellGO:19035321280.035
response to ketoneGO:19016541820.035
cellular response to hormone stimulusGO:00328702470.035
actin cytoskeleton organizationGO:0030036730.035
behaviorGO:00076102050.035
regulation of exocytosisGO:0017157370.035
peptidyl amino acid modificationGO:00181931260.035
positive regulation of endothelial cell differentiationGO:004560320.034
protein oligomerizationGO:00512591910.034
cellular divalent inorganic cation homeostasisGO:00725031620.034
positive regulation of cell proliferationGO:00082842490.034
positive regulation of protein metabolic processGO:00512471780.034
negative regulation of chronic inflammatory responseGO:000267720.033
glomerulus morphogenesisGO:007210210.033
axon developmentGO:0061564960.033
positive regulation of interleukin 1 beta secretionGO:005071830.033
cellular cation homeostasisGO:00300031800.032
regulation of neurotransmitter levelsGO:0001505420.032
lymphocyte chemotaxisGO:004824730.032
muscle contractionGO:0006936880.032
cellular amine metabolic processGO:0044106380.032
organic anion transportGO:00157111320.031
regulation of membrane potentialGO:00423911100.031
rna metabolic processGO:00160704060.031
regulation of cellular amino acid metabolic processGO:000652120.031
central nervous system developmentGO:00074173110.030
regulation of activation of janus kinase activityGO:001053310.030
gastrulationGO:000736920.030
single organism catabolic processGO:00447122830.030
multi organism reproductive processGO:00447032620.030
leukocyte activationGO:0045321760.030
positive regulation of gene expressionGO:00106282440.029
organ morphogenesisGO:0009887750.029
entrainment of circadian clockGO:000964930.029
positive regulation of synapse maturationGO:009012920.029
negative regulation of developmental processGO:00510931250.029
gland developmentGO:00487321550.029
positive regulation of cellular biosynthetic processGO:00313282950.029
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252410.028
limb morphogenesisGO:003510840.028
positive regulation of interleukin 18 productionGO:003274110.028
organic hydroxy compound metabolic processGO:19016151150.028
motor neuron axon guidanceGO:000804510.028
cellular homeostasisGO:00197252520.027
hindlimb morphogenesisGO:003513720.027
positive regulation of programmed cell deathGO:00430681570.026
response to toxic substanceGO:00096361330.026
heart contractionGO:0060047570.026
establishment of organelle localizationGO:0051656370.026
cell activationGO:0001775970.026
response to metal ionGO:00100382530.026
rna biosynthetic processGO:00327743800.026
cell type specific apoptotic processGO:00972851340.026
regulated secretory pathwayGO:0045055170.026
organic substance catabolic processGO:19015753160.026
cation transmembrane transportGO:00986552630.026
modified amino acid transportGO:0072337120.026
positive regulation of interleukin 1 secretionGO:005071630.026
regulation of cyclic nucleotide metabolic processGO:0030799510.025
carnitine transportGO:001587910.025
regulation of cellular component movementGO:00512701500.025
epithelium developmentGO:0060429960.025
olfactory learningGO:000835510.025
regulation of synaptic plasticityGO:0048167700.025
negative regulation of cellular component organizationGO:0051129830.025
mast cell migrationGO:009753140.025
positive regulation of cell differentiationGO:00455972170.025
response to growth factorGO:00708481890.025
developmental process involved in reproductionGO:00030061590.024
response to electrical stimulusGO:0051602560.024
cellular response to peptideGO:19016531330.024
regulation of cell migrationGO:00303341280.024
positive regulation of nitrogen compound metabolic processGO:00511733340.024
regulation of neutrophil chemotaxisGO:009002250.024
neuronal stem cell maintenanceGO:009715020.023
long chain fatty acid transportGO:0015909140.023
negative regulation of neuron differentiationGO:0045665620.023
organelle localizationGO:0051640550.023
cytosolic calcium ion homeostasisGO:00514801400.023
sexual reproductionGO:00199531480.023
positive regulation of exocytosisGO:0045921190.023
negative regulation of apoptotic processGO:00430661810.023
morphogenesis of a polarized epitheliumGO:000173810.023
cell migrationGO:00164771970.023
dephosphorylationGO:0016311980.023
neuron projection morphogenesisGO:00488121220.022
vesicle localizationGO:0051648330.022
inflammatory cell apoptotic processGO:000692550.022
secretion by cellGO:00329402480.022
embryonic limb morphogenesisGO:003032640.022
regulation of establishment of protein localizationGO:0070201690.022
regulation of secretionGO:00510462240.022
response to radiationGO:00093141370.022
calcium ion transmembrane transportGO:0070588700.022
response to acid chemicalGO:00011012220.022
positive regulation of secretionGO:00510471400.022
regulation of purine nucleotide metabolic processGO:19005421150.021
regulation of endothelial cell differentiationGO:004560140.021
negative regulation of neutrophil apoptotic processGO:003303030.021
protein localizationGO:00081041910.021
cellular response to growth factor stimulusGO:00713631620.021
regulation of neuron apoptotic processGO:0043523830.021
response to peptideGO:19016522920.021
negative regulation of cell proliferationGO:00082851190.021
negative regulation of cellular protein metabolic processGO:00322691060.021
regulation of nucleic acid templated transcriptionGO:19035063800.021
ribose phosphate metabolic processGO:00196932350.021
transmembrane transportGO:00550854120.020
synaptic vesicle endocytosisGO:004848840.020
inorganic ion transmembrane transportGO:00986602290.020
transcription dna templatedGO:00063513770.020
negative regulation of cell differentiationGO:0045596990.020
regulation of cell motilityGO:20001451310.020
glutathione transportGO:003463520.020
regulation of immune system processGO:00026821230.020
mast cell chemotaxisGO:000255140.020
taxisGO:0042330670.020
endosomal lumen acidificationGO:004838810.020
cellular response to acid chemicalGO:0071229750.020
positive regulation of protein secretionGO:0050714190.020
response to amino acidGO:0043200750.020
regulation of protein localizationGO:0032880810.020
cell part morphogenesisGO:00329901230.019
respiratory system developmentGO:0060541450.019
leukocyte differentiationGO:0002521300.019
response to retinoic acidGO:0032526630.019
axonogenesisGO:0007409710.019
positive regulation of hydrolase activityGO:0051345860.019
regulation of metal ion transportGO:00109591180.019
Rat
myeloid leukocyte activationGO:0002274360.019
negative regulation of phosphorylationGO:0042326570.019
intracellular transportGO:00469071850.019
regulation of cell activationGO:0050865500.019
protein complex biogenesisGO:00702712630.019
metal ion homeostasisGO:00550651860.019
anatomical structure formation involved in morphogenesisGO:0048646830.019
response to muscle stretchGO:003599420.019
cell morphogenesis involved in differentiationGO:00009041190.019
cell motilityGO:00488702020.018
negative regulation of neuron deathGO:1901215690.018
cellular component morphogenesisGO:00329891550.018
regulation of cell morphogenesisGO:0022604770.018
regulation of cellular localizationGO:00603412630.018
cellular response to oxygen containing compoundGO:19017013860.018
myeloid cell activation involved in immune responseGO:0002275130.018
single organism behaviorGO:00447081300.018
regulation of muscle contractionGO:0006937530.018
extracellular structure organizationGO:0043062130.018
positive regulation of purine nucleotide metabolic processGO:1900544910.018
cell cell junction organizationGO:0045216200.018
regulation of programmed cell deathGO:00430673410.018
single organism biosynthetic processGO:00447113420.018
regulation of neuron deathGO:19012141150.018
meiotic cell cycle processGO:190304630.018
amino acid transportGO:0006865700.018
positive regulation of locomotionGO:00400171020.018
divalent metal ion transportGO:00708381320.018
regulation of neutrophil apoptotic processGO:003302940.018
regulation of organelle organizationGO:0033043800.017
macromolecular complex assemblyGO:00650032730.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
angiogenesisGO:0001525530.017
negative regulation of multicellular organismal processGO:00512412030.017
cell cycle processGO:0022402570.017
prostate gland epithelium morphogenesisGO:006074020.017
regulation of map kinase activityGO:0043405530.017
negative regulation of response to stimulusGO:00485851550.017
inner ear developmentGO:0048839210.017
peptidyl tyrosine modificationGO:0018212720.017
transmission of nerve impulseGO:0019226420.017
inflammatory response to antigenic stimulusGO:0002437180.017
neuroblast differentiationGO:001401610.017
negative regulation of protein metabolic processGO:00512481140.017
regulation of rna metabolic processGO:00512523910.017
positive regulation of blood circulationGO:1903524650.016
extracellular matrix organizationGO:0030198130.016
cellular response to hypoxiaGO:0071456510.016
negative regulation of protein import into nucleus translocationGO:003315910.016
phasic smooth muscle contractionGO:001482130.016
nucleoside phosphate metabolic processGO:00067532830.016
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.016
regulation of circadian sleep wake cycleGO:0042749180.016
positive regulation of apoptotic processGO:00430651540.016
establishment of protein localizationGO:00451841410.016
cyclic nucleotide biosynthetic processGO:0009190630.016
t cell differentiationGO:003021790.016
chronic inflammatory response to non antigenic stimulusGO:000254510.016
gamete generationGO:00072761240.016
embryonic appendage morphogenesisGO:003511340.016
second messenger mediated signalingGO:0019932510.016
negative regulation of intracellular signal transductionGO:1902532380.016
positive regulation of action potentialGO:004576080.016
endocytosisGO:0006897840.016
Rat
neurotransmitter secretionGO:0007269330.016
cell activation involved in immune responseGO:0002263160.016
regulation of chemotaxisGO:0050920290.016
t cell migrationGO:007267820.015
urinary tract smooth muscle contractionGO:001484840.015
eye morphogenesisGO:004859240.015
regulation of rna biosynthetic processGO:20011413810.015
cell growthGO:00160491040.015
muscle cell proliferationGO:0033002840.015
positive regulation of epithelial cell proliferationGO:0050679320.015
maintenance of locationGO:0051235170.015
cell junction organizationGO:0034330210.015
ribonucleotide biosynthetic processGO:0009260850.015
response to cgmpGO:007030530.015
sex differentiationGO:00075481130.015
immune system processGO:00023762040.015
vesicle organizationGO:0016050290.015
regulation of neurotransmitter transportGO:0051588210.015
negative regulation of cell communicationGO:00106481580.015
cytoplasmic transportGO:00164821150.015
developmental growthGO:00485891000.015
positive regulation of cyclic nucleotide metabolic processGO:0030801370.015
cellular catabolic processGO:00442482950.015
cell projection morphogenesisGO:00488581230.015
sex determinationGO:000753020.015
cell cycleGO:00070491010.014
organophosphate biosynthetic processGO:00904071430.014
regulation of nucleotide metabolic processGO:00061401170.014
nucleotide metabolic processGO:00091172790.014
establishment of planar polarityGO:000173610.014
olfactory behaviorGO:004204820.014
negative regulation of neuron apoptotic processGO:0043524450.014
sensory perceptionGO:00076001010.014
cell substrate adhesionGO:0031589290.014
carbohydrate derivative metabolic processGO:19011353460.014
striated muscle contractionGO:0006941440.014
leukocyte mediated immunityGO:0002443280.014
serotonin metabolic processGO:004242830.014
purine ribonucleotide metabolic processGO:00091502270.014
glomerular epithelial cell differentiationGO:007231120.014
positive regulation of map kinase activityGO:0043406460.014
rho protein signal transductionGO:0007266110.014
response to molecule of bacterial originGO:00022371940.014
regulation of axonogenesisGO:0050770370.014
salivary gland developmentGO:000743130.014
muscle system processGO:00030121150.014
negative regulation of signalingGO:00230571570.014
sequestering of calcium ionGO:005120880.014
cellular response to cgmpGO:007132120.014
negative regulation of transcription dna templatedGO:00458921160.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
regulation of cytoskeleton organizationGO:0051493490.014
response to purine containing compoundGO:00140741260.013
inner ear morphogenesisGO:004247210.013
single organism carbohydrate metabolic processGO:00447231180.013
angioblast cell migrationGO:003547610.013
neuropeptide signaling pathwayGO:0007218290.013
organic acid metabolic processGO:00060822920.013
activation of mapkk activityGO:0000186180.013
carbohydrate metabolic processGO:00059751300.013
cellular response to lipidGO:00713962010.013
peptidyl tyrosine phosphorylationGO:0018108720.013
cellular component movementGO:00069282480.013
regulation of intracellular transportGO:0032386650.013
tube morphogenesisGO:0035239230.013
response to transition metal nanoparticleGO:19902671220.013
negative regulation of neuron projection developmentGO:0010977460.013
regulation of behaviorGO:0050795610.013
anion transmembrane transportGO:0098656770.013
regulation of response to stressGO:00801341260.013
brain developmentGO:00074202470.013
behavioral response to painGO:004826650.013
response to ethanolGO:00454711620.013
regulation of ion transmembrane transporter activityGO:0032412480.013
prostaglandin secretionGO:003231060.013
response to mechanical stimulusGO:00096121340.013
leukocyte migrationGO:0050900380.013
regulation of ion transmembrane transportGO:00347651210.013
lung lobe developmentGO:006046210.013
cytoskeleton dependent cytokinesisGO:006164020.013
positive regulation of cardiac muscle contractionGO:006045240.013
negative regulation of calcium ion importGO:009028120.013
response to molecule of fungal originGO:000223830.013
positive regulation of transportGO:00510502450.013
calcium ion transportGO:00068161310.013
negative regulation of growthGO:0045926370.012
morphogenesis of an epitheliumGO:0002009200.012
regulation of developmental growthGO:0048638450.012
regulation of homeostatic processGO:00328441010.012
heart formationGO:006091410.012
regulation of transmembrane transportGO:00347621220.012
single organism cellular localizationGO:19025801020.012
purine containing compound metabolic processGO:00725212530.012
neurological system processGO:00508772190.012
single organism intracellular transportGO:19025821660.012
male gamete generationGO:0048232990.012
regenerationGO:00310991630.012
cellular response to abiotic stimulusGO:0071214850.012
regulation of l glutamate transportGO:000203610.012
digestive tract developmentGO:0048565390.012
nucleobase containing small molecule metabolic processGO:00550863160.012
adult locomotory behaviorGO:000834440.012
photoperiodismGO:000964840.012
regulation of cellular ketone metabolic processGO:0010565270.012
cgmp biosynthetic processGO:0006182150.012
regulation of leukocyte activationGO:0002694450.012
multicellular organismal signalingGO:0035637440.012
spermatogenesisGO:0007283990.012
reproductive structure developmentGO:00486081280.012
purine nucleotide metabolic processGO:00061632290.012
alcohol metabolic processGO:0006066770.012
sequestering of metal ionGO:005123890.012
regulation of transcription dna templatedGO:00063553740.012
artery developmentGO:006084030.012
negative regulation of programmed cell deathGO:00430691830.012
regulation of cellular component biogenesisGO:0044087860.012

Slc9a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
neuropathyDOID:87000.063
nervous system diseaseDOID:86300.063
disease of anatomical entityDOID:700.063
neuromuscular diseaseDOID:44000.063
cardiovascular system diseaseDOID:128700.033
central nervous system diseaseDOID:33100.023
musculoskeletal system diseaseDOID:1700.020
immune system diseaseDOID:291400.013
primary immunodeficiency diseaseDOID:61200.013
disease of cellular proliferationDOID:1456600.012
benign neoplasmDOID:006007200.012
bone diseaseDOID:008000100.012
connective tissue diseaseDOID:6500.012