Rattus norvegicus

0 known processes

Sim2

single-minded homolog 2 (Drosophila)

Sim2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to acid chemicalGO:00011012220.082
Rat
rna biosynthetic processGO:00327743800.061
Rat
cellular response to oxygen containing compoundGO:19017013860.058
Rat
anatomical structure morphogenesisGO:00096532980.056
programmed cell deathGO:00125013920.052
Rat
regulation of transcription dna templatedGO:00063553740.048
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.048
Rat
regulation of rna biosynthetic processGO:20011413810.045
Rat
regulation of programmed cell deathGO:00430673410.045
Rat
nucleic acid templated transcriptionGO:00976593790.043
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.042
Rat
multi organism reproductive processGO:00447032620.039
Rat
positive regulation of biosynthetic processGO:00098913190.038
Rat
multicellular organism reproductionGO:00325042330.038
Rat
response to inorganic substanceGO:00100353770.038
Rat
regulation of nucleic acid templated transcriptionGO:19035063800.037
Rat
negative regulation of cellular metabolic processGO:00313242810.035
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.034
Rat
regulation of rna metabolic processGO:00512523910.034
Rat
multicellular organismal reproductive processGO:00486092330.034
Rat
negative regulation of cell deathGO:00605482290.033
Rat
negative regulation of nucleic acid templated transcriptionGO:19035071170.033
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.032
Rat
reproductionGO:00000032450.032
Rat
cellular response to external stimulusGO:00714961180.032
Rat
apoptotic processGO:00069153810.030
Rat
negative regulation of rna metabolic processGO:00512531230.030
Rat
negative regulation of apoptotic processGO:00430661810.030
Rat
negative regulation of macromolecule metabolic processGO:00106052600.030
Rat
transcription dna templatedGO:00063513770.030
Rat
rna metabolic processGO:00160704060.030
Rat
regulation of signal transductionGO:00099663180.030
negative regulation of rna biosynthetic processGO:19026791180.029
Rat
positive regulation of transcription dna templatedGO:00458931970.029
Rat
cellular response to lipidGO:00713962010.029
Rat
protein phosphorylationGO:00064683450.029
response to nutrient levelsGO:00316673700.029
positive regulation of cell deathGO:00109421840.028
Rat
response to growth factorGO:00708481890.028
negative regulation of transcription dna templatedGO:00458921160.027
Rat
regulation of cellular protein metabolic processGO:00322682670.027
regulation of catalytic activityGO:00507903040.027
regulation of phosphorylationGO:00423252480.027
intracellular signal transductionGO:00355563140.027
cellular response to endogenous stimulusGO:00714953770.027
Rat
single organism biosynthetic processGO:00447113420.027
regulation of protein phosphorylationGO:00019321830.026
regulation of cellular ketone metabolic processGO:0010565270.026
negative regulation of gene expressionGO:00106291990.026
Rat
regulation of apoptotic processGO:00429813350.026
Rat
response to estrogenGO:00436272320.026
Rat
negative regulation of metabolic processGO:00098923310.026
Rat
regulation of hormone levelsGO:00108171870.025
regulation of protein metabolic processGO:00512462890.025
regulation of phosphorus metabolic processGO:00511743490.025
response to estradiolGO:00323551640.025
Rat
regulation of phosphate metabolic processGO:00192203490.025
cellular component assemblyGO:00226073600.025
negative regulation of nucleobase containing compound metabolic processGO:00459341530.024
Rat
response to peptideGO:19016522920.024
Rat
single organism reproductive processGO:00447022970.024
Rat
cellular response to organic cyclic compoundGO:00714072020.024
Rat
agingGO:00075682410.024
negative regulation of biosynthetic processGO:00098901680.024
Rat
response to radiationGO:00093141370.023
Rat
cellular ketone metabolic processGO:0042180510.023
regulation of cellular amino acid metabolic processGO:000652120.023
regulation of cell proliferationGO:00421273590.023
Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
Rat
regulation of molecular functionGO:00650093980.023
positive regulation of signalingGO:00230562700.023
growthGO:00400071650.023
single organism catabolic processGO:00447122830.023
regulation of cellular amine metabolic processGO:003323880.022
tissue developmentGO:00098882520.022
regulation of multicellular organismal developmentGO:20000263760.022
positive regulation of nucleobase containing compound metabolic processGO:00459353190.022
Rat
organelle organizationGO:00069962660.022
catabolic processGO:00090563510.021
transcription from rna polymerase ii promoterGO:00063662520.021
Rat
circulatory system developmentGO:00723591340.021
macromolecular complex subunit organizationGO:00439333390.021
sexual reproductionGO:00199531480.021
positive regulation of gene expressionGO:00106282440.021
Rat
positive regulation of response to stimulusGO:00485842850.021
positive regulation of protein metabolic processGO:00512471780.021
response to nutrientGO:00075842480.021
amine metabolic processGO:0009308380.021
response to hypoxiaGO:00016662310.021
Rat
regulation of cell differentiationGO:00455953200.021
neuron differentiationGO:00301823680.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
Rat
central nervous system developmentGO:00074173110.021
positive regulation of cellular biosynthetic processGO:00313282950.020
Rat
positive regulation of rna biosynthetic processGO:19026801970.020
Rat
positive regulation of developmental processGO:00510942830.020
brain developmentGO:00074202470.020
positive regulation of cell proliferationGO:00082842490.020
Rat
regulation of intracellular signal transductionGO:19025312180.020
positive regulation of signal transductionGO:00099671750.020
organ morphogenesisGO:0009887750.020
localization of cellGO:00516742020.019
cellular component biogenesisGO:00440853680.019
cellular amine metabolic processGO:0044106380.019
cellular response to organonitrogen compoundGO:00714171970.019
Rat
cellular homeostasisGO:00197252520.019
Rat
reproductive processGO:00224143720.019
Rat
response to woundingGO:00096112540.019
single organism organelle organizationGO:19025891800.019
immune system processGO:00023762040.019
positive regulation of cellular protein metabolic processGO:00322701670.019
organic substance catabolic processGO:19015753160.019
negative regulation of cellular biosynthetic processGO:00313271610.018
Rat
secretionGO:00469033070.018
neuron developmentGO:00486662860.018
positive regulation of rna metabolic processGO:00512542030.018
Rat
response to oxidative stressGO:00069791860.018
Rat
positive regulation of apoptotic processGO:00430651540.018
Rat
cellular component movementGO:00069282480.018
positive regulation of cellular amine metabolic processGO:003324030.018
cellular catabolic processGO:00442482950.018
inorganic ion transmembrane transportGO:00986602290.018
positive regulation of multicellular organismal processGO:00512403870.018
regulation of cellular component organizationGO:00511283680.018
biological adhesionGO:00226101100.017
regulation of neurogenesisGO:00507672470.017
cellular response to acid chemicalGO:0071229750.017
Rat
positive regulation of phosphate metabolic processGO:00459372620.017
response to oxygen levelsGO:00704822650.017
Rat
response to other organismGO:00517072200.017
Rat
cellular amino acid metabolic processGO:00065201070.017
response to decreased oxygen levelsGO:00362932370.017
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.017
Rat
positive regulation of cell communicationGO:00106472710.017
positive regulation of molecular functionGO:00440932300.017
transmembrane transportGO:00550854120.017
organic acid metabolic processGO:00060822920.016
cellular response to peptideGO:19016531330.016
Rat
cardiovascular system developmentGO:00723581340.016
response to bacteriumGO:00096172000.016
Rat
negative regulation of programmed cell deathGO:00430691830.016
Rat
regulation of cell developmentGO:00602842630.016
multicellular organism growthGO:003526410.016
positive regulation of protein modification processGO:00314011420.016
regulation of system processGO:00440572080.016
Rat
organophosphate metabolic processGO:00196373700.016
positive regulation of phosphorus metabolic processGO:00105622620.016
cell morphogenesisGO:00009021420.016
cell projection organizationGO:00300303020.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
response to carbohydrateGO:00097431830.016
Rat
neuron projection developmentGO:00311752730.016
positive regulation of immune system processGO:0002684900.016
response to biotic stimulusGO:00096072260.016
Rat
circulatory system processGO:00030131830.016
Rat
positive regulation of cellular component organizationGO:00511302000.015
head developmentGO:00603222470.015
protein complex biogenesisGO:00702712630.015
metal ion transportGO:00300012890.015
positive regulation of programmed cell deathGO:00430681570.015
Rat
response to metal ionGO:00100382530.015
Rat
gamete generationGO:00072761240.015
cell migrationGO:00164771970.015
cellular response to stressGO:00335542690.015
Rat
peptidyl amino acid modificationGO:00181931260.015
homeostatic processGO:00425923310.015
Rat
carboxylic acid metabolic processGO:00197522890.015
secretion by cellGO:00329402480.014
neurological system processGO:00508772190.014
regulation of cell projection organizationGO:00313441750.014
cell adhesionGO:00071551100.014
regulation of nervous system developmentGO:00519602640.014
chemical homeostasisGO:00488782920.014
Rat
establishment of protein localizationGO:00451841410.014
macromolecule localizationGO:00330362520.014
cellular response to hormone stimulusGO:00328702470.014
Rat
response to vitaminGO:00332731310.014
positive regulation of phosphorylationGO:00423271770.014
macromolecular complex assemblyGO:00650032730.014
oxoacid metabolic processGO:00434362900.014
appendage morphogenesisGO:003510740.014
cellular response to nitrogen compoundGO:19016992100.014
Rat
ion transmembrane transportGO:00342203650.014
cellular response to growth factor stimulusGO:00713631620.013
response to extracellular stimulusGO:00099913800.013
positive regulation of protein phosphorylationGO:00019341350.013
protein oligomerizationGO:00512591910.013
regulation of neuron differentiationGO:00456642080.013
rhythmic processGO:00485111560.013
male gamete generationGO:0048232990.013
negative regulation of molecular functionGO:00440921330.013
carbohydrate derivative metabolic processGO:19011353460.013
protein complex subunit organizationGO:00718223020.013
regulation of immune system processGO:00026821230.013
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.013
Rat
regenerationGO:00310991630.013
proteolysisGO:00065081750.013
nucleotide metabolic processGO:00091172790.012
aromatic compound catabolic processGO:00194391680.012
embryonic skeletal system developmentGO:004870630.012
spermatogenesisGO:0007283990.012
divalent inorganic cation homeostasisGO:00725071650.012
positive regulation of catalytic activityGO:00430851840.012
cellular response to oxidative stressGO:0034599760.012
Rat
response to cytokineGO:00340972150.012
Rat
multi multicellular organism processGO:00447061380.012
Rat
muscle system processGO:00030121150.012
carbohydrate metabolic processGO:00059751300.012
ion homeostasisGO:00508012120.012
positive regulation of intracellular signal transductionGO:19025331380.012
positive regulation of transportGO:00510502450.012
negative regulation of multicellular organismal processGO:00512412030.012
Rat
negative regulation of cellular protein metabolic processGO:00322691060.012
positive regulation of cell projection organizationGO:00313461110.012
regulation of stem cell differentiationGO:200073620.012
cellular cation homeostasisGO:00300031800.012
small gtpase mediated signal transductionGO:0007264360.012
defense responseGO:00069521940.012
ras protein signal transductionGO:0007265290.012
response to increased oxygen levelsGO:0036296450.012
response to corticosteroidGO:00319602350.012
Rat
response to retinoic acidGO:0032526630.012
nucleobase containing small molecule metabolic processGO:00550863160.012
response to peptide hormoneGO:00434342780.012
Rat
negative regulation of catalytic activityGO:00430861030.011
cation transportGO:00068123820.011
cell cell signalingGO:00072673350.011
cation transmembrane transportGO:00986552630.011
lipid metabolic processGO:00066292830.011
regulation of protein modification processGO:00313991940.011
nucleoside phosphate metabolic processGO:00067532830.011
regulation of hydrolase activityGO:00513361430.011
positive regulation of cell differentiationGO:00455972170.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
Rat
cell growthGO:00160491040.011
gastrulationGO:000736920.011
negative regulation of response to stimulusGO:00485851550.011
negative regulation of cell differentiationGO:0045596990.011
positive regulation of neurogenesisGO:00507691650.011
response to mechanical stimulusGO:00096121340.011
Rat
rho protein signal transductionGO:0007266110.011
cell morphogenesis involved in differentiationGO:00009041190.011
oxidation reduction processGO:00551143040.011
muscle cell proliferationGO:0033002840.011
Rat
regulation of cell migrationGO:00303341280.011
membrane organizationGO:0061024940.011
axis specificationGO:000979840.010
inflammatory responseGO:00069541500.010
embryonic appendage morphogenesisGO:003511340.010
metal ion homeostasisGO:00550651860.010
regulation of secretion by cellGO:19035302080.010
developmental process involved in reproductionGO:00030061590.010
regulation of cell cycleGO:0051726730.010
sequestering of metal ionGO:005123890.010
regulation of proteasomal protein catabolic processGO:006113640.010
cytoskeleton organizationGO:00070101110.010

Sim2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.028
nervous system diseaseDOID:86300.014
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.011
central nervous system diseaseDOID:33100.010