IMP: Integrative Multi-species Prediction

Rattus norvegicus

28 known processes

Faah

fatty acid amide hydrolase

RGD: 61808
Ensembl: ENSRNOG00000011019
Entrez: 29347
UniProtKB: P97612

Process Predictions
Disease Predictions

Faah biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
carbohydrate metabolic process	GO:0005975	130	0.278
cellular lipid metabolic process	GO:0044255	208	0.217
vesicle mediated transport	GO:0016192	181	0.215
lipid metabolic process	GO:0006629	283	0.214
transmembrane transport	GO:0055085	412	0.115
hexose metabolic process	GO:0019318	58	0.091
regulation of vesicle mediated transport	GO:0060627	81	0.090
fructose metabolic process	GO:0006000	1	0.087
monosaccharide metabolic process	GO:0005996	61	0.083
organophosphate metabolic process	GO:0019637	370	0.082
response to peptide	GO:1901652	292	0.080
response to carbohydrate	GO:0009743	183	0.079
synaptic transmission	GO:0007268	235	0.079
response to insulin	GO:0032868	133	0.073
synaptic vesicle localization	GO:0097479	24	0.070
carboxylic acid metabolic process	GO:0019752	289	0.068
regulation of cellular component organization	GO:0051128	368	0.068
carbohydrate phosphorylation	GO:0046835	16	0.067
multicellular organism growth	GO:0035264	1	0.063
cellular nitrogen compound catabolic process	GO:0044270	163	0.062
carboxylic acid biosynthetic process	GO:0046394	83	0.061
organic substance catabolic process	GO:1901575	316	0.061
glycerolipid metabolic process	GO:0046486	67	0.061
ion transmembrane transport	GO:0034220	365	0.060
cation transmembrane transport	GO:0098655	263	0.053
positive regulation of endocytosis	GO:0045807	28	0.052
receptor localization to synapse	GO:0097120	2	0.050
glucose metabolic process	GO:0006006	52	0.044
single organism organelle organization	GO:1902589	180	0.043
single organism biosynthetic process	GO:0044711	342	0.043
organelle organization	GO:0006996	266	0.043
intracellular transport	GO:0046907	185	0.042
regulation of synaptic transmission	GO:0050804	141	0.041
response to metal ion	GO:0010038	253	0.040
positive regulation of cell development	GO:0010720	176	0.039
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.039
cellular component assembly	GO:0022607	360	0.037
glutamate receptor signaling pathway	GO:0007215	43	0.037
organic cyclic compound catabolic process	GO:1901361	175	0.037
carbohydrate derivative metabolic process	GO:1901135	346	0.036
response to monosaccharide	GO:0034284	159	0.036
detection of stimulus	GO:0051606	24	0.035
macromolecular complex subunit organization	GO:0043933	339	0.035
synapse assembly	GO:0007416	29	0.035
response to peptide hormone	GO:0043434	278	0.035
glycosyl compound catabolic process	GO:1901658	126	0.034
regulation of cell differentiation	GO:0045595	320	0.034
head development	GO:0060322	247	0.033
regulation of synaptic vesicle endocytosis	GO:1900242	1	0.033
single organism carbohydrate metabolic process	GO:0044723	118	0.033
positive regulation of synaptic vesicle exocytosis	GO:2000302	3	0.033
cellular response to peptide hormone stimulus	GO:0071375	120	0.033
positive regulation of transport	GO:0051050	245	0.032
dephosphorylation	GO:0016311	98	0.032
neurotransmitter transport	GO:0006836	42	0.032
response to oxidative stress	GO:0006979	186	0.032
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.031
aromatic compound catabolic process	GO:0019439	168	0.031
positive regulation of synaptic vesicle recycling	GO:1903423	1	0.030
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.029
membrane organization	GO:0061024	94	0.029
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.029
negative regulation of innate immune response	GO:0045824	4	0.029
synaptic vesicle transport	GO:0048489	23	0.029
regulation of nervous system development	GO:0051960	264	0.028
regulation of neuron projection development	GO:0010975	161	0.028
response to acid chemical	GO:0001101	222	0.027
regulation of neuron differentiation	GO:0045664	208	0.027
response to nutrient levels	GO:0031667	370	0.027
organic hydroxy compound metabolic process	GO:1901615	115	0.027
endocytosis	GO:0006897	84	0.027
regulation of molecular function	GO:0065009	398	0.026
hepaticobiliary system development	GO:0061008	90	0.026
organophosphate catabolic process	GO:0046434	148	0.026
intracellular protein transport	GO:0006886	79	0.025
nucleoside phosphate metabolic process	GO:0006753	283	0.025
heterocycle catabolic process	GO:0046700	167	0.025
signal release	GO:0023061	145	0.025
presynaptic membrane assembly	GO:0097105	3	0.025
protein homooligomerization	GO:0051260	91	0.025
neuron differentiation	GO:0030182	368	0.025
postsynaptic density protein 95 clustering	GO:0097119	2	0.025
regulation of neurotransmitter levels	GO:0001505	42	0.024
response to ketone	GO:1901654	182	0.024
response to starvation	GO:0042594	59	0.023
cellular component biogenesis	GO:0044085	368	0.023
negative regulation of metabolic process	GO:0009892	331	0.023
negative regulation of molecular function	GO:0044092	133	0.023
purine ribonucleoside catabolic process	GO:0046130	124	0.023
phosphatidylinositol dephosphorylation	GO:0046856	4	0.023
protein complex biogenesis	GO:0070271	263	0.023
brain development	GO:0007420	247	0.023
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.022
regulation of neurogenesis	GO:0050767	247	0.022
serine family amino acid metabolic process	GO:0009069	12	0.022
cellular response to peptide	GO:1901653	133	0.022
cellular homeostasis	GO:0019725	252	0.022
purine nucleotide metabolic process	GO:0006163	229	0.021
adult locomotory behavior	GO:0008344	4	0.021
positive regulation of calcium ion dependent exocytosis	GO:0045956	6	0.021
liver development	GO:0001889	90	0.021
positive regulation of cell differentiation	GO:0045597	217	0.021
urea metabolic process	GO:0019627	5	0.021
oxoacid metabolic process	GO:0043436	290	0.021
regulation of carbohydrate metabolic process	GO:0006109	41	0.021
metal ion transport	GO:0030001	289	0.021
activation of protein kinase b activity	GO:0032148	3	0.021
cellular response to insulin stimulus	GO:0032869	81	0.021
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.021
establishment of organelle localization	GO:0051656	37	0.021
synaptic vesicle exocytosis	GO:0016079	15	0.020
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.020
reproductive process	GO:0022414	372	0.020
response to extracellular stimulus	GO:0009991	380	0.020
actin crosslink formation	GO:0051764	3	0.020
carbohydrate derivative catabolic process	GO:1901136	147	0.020
nucleobase containing compound catabolic process	GO:0034655	152	0.020
positive regulation of synaptic vesicle transport	GO:1902805	3	0.020
response to radiation	GO:0009314	137	0.020
neurological system process	GO:0050877	219	0.020
regulation of dendrite morphogenesis	GO:0048814	33	0.020
ribonucleoside metabolic process	GO:0009119	174	0.020
inorganic ion transmembrane transport	GO:0098660	229	0.020
purine containing compound catabolic process	GO:0072523	138	0.019
positive regulation of neuron differentiation	GO:0045666	126	0.019
cerebellar purkinje cell layer development	GO:0021680	2	0.019
cellular amine metabolic process	GO:0044106	38	0.019
cellular response to oxygen containing compound	GO:1901701	386	0.019
nucleotide metabolic process	GO:0009117	279	0.019
regulation of catalytic activity	GO:0050790	304	0.019
negative regulation of cell communication	GO:0010648	158	0.018
response to ethanol	GO:0045471	162	0.018
gamma aminobutyric acid secretion	GO:0014051	6	0.018
aging	GO:0007568	241	0.018
ribose phosphate metabolic process	GO:0019693	235	0.018
cell cell signaling	GO:0007267	335	0.018
oxidation reduction process	GO:0055114	304	0.018
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.018
cellular catabolic process	GO:0044248	295	0.018
positive regulation of cell projection organization	GO:0031346	111	0.018
synaptic growth at neuromuscular junction	GO:0051124	1	0.018
regulation of cell development	GO:0060284	263	0.018
positive regulation of synaptic vesicle endocytosis	GO:1900244	1	0.017
coenzyme metabolic process	GO:0006732	86	0.017
ion homeostasis	GO:0050801	212	0.017
regulation of hormone levels	GO:0010817	187	0.017
atp metabolic process	GO:0046034	72	0.017
nucleotide catabolic process	GO:0009166	139	0.017
regulation of long term neuronal synaptic plasticity	GO:0048169	15	0.016
serine family amino acid biosynthetic process	GO:0009070	4	0.016
positive regulation of neuron projection development	GO:0010976	99	0.016
nucleoside catabolic process	GO:0009164	126	0.016
central nervous system development	GO:0007417	311	0.016
chromosome segregation	GO:0007059	2	0.016
divalent metal ion transport	GO:0070838	132	0.016
regulation of respiratory gaseous exchange	GO:0043576	2	0.016
inorganic cation transmembrane transport	GO:0098662	202	0.016
protein autophosphorylation	GO:0046777	66	0.016
positive regulation of nervous system development	GO:0051962	178	0.016
positive regulation of molecular function	GO:0044093	230	0.016
cellular component maintenance	GO:0043954	4	0.016
response to hexose	GO:0009746	144	0.016
regulation of anatomical structure size	GO:0090066	135	0.016
sensory organ development	GO:0007423	74	0.015
response to camp	GO:0051591	91	0.015
negative regulation of phosphate metabolic process	GO:0045936	80	0.015
neuromuscular process	GO:0050905	2	0.015
negative regulation of cellular metabolic process	GO:0031324	281	0.015
monocarboxylic acid metabolic process	GO:0032787	152	0.015
positive regulation of cellular component organization	GO:0051130	200	0.015
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering	GO:0097113	2	0.015
organonitrogen compound biosynthetic process	GO:1901566	167	0.015
alcohol metabolic process	GO:0006066	77	0.015
chemosensory behavior	GO:0007635	2	0.015
lipid modification	GO:0030258	52	0.015
exocytosis	GO:0006887	60	0.015
protein localization	GO:0008104	191	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
salivary gland development	GO:0007431	3	0.015
organic hydroxy compound biosynthetic process	GO:1901617	51	0.015
ribonucleoside catabolic process	GO:0042454	126	0.015
regulation of organelle organization	GO:0033043	80	0.015
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.015
regulation of hydrolase activity	GO:0051336	143	0.015
regulation of endocytosis	GO:0030100	42	0.014
cellular sodium ion homeostasis	GO:0006883	4	0.014
fructose 2 6 bisphosphate metabolic process	GO:0006003	2	0.014
cellular carbohydrate metabolic process	GO:0044262	72	0.014
negative regulation of camp metabolic process	GO:0030815	14	0.014
response to axon injury	GO:0048678	59	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
cell projection organization	GO:0030030	302	0.014
single organism catabolic process	GO:0044712	283	0.014
regulation of cellular carbohydrate metabolic process	GO:0010675	39	0.014
glycosyl compound metabolic process	GO:1901657	182	0.014
cellular response to nitrogen compound	GO:1901699	210	0.014
macromolecular complex assembly	GO:0065003	273	0.014
carbohydrate catabolic process	GO:0016052	40	0.014
neuromuscular synaptic transmission	GO:0007274	2	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
early endosome to late endosome transport	GO:0045022	2	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.014
generation of precursor metabolites and energy	GO:0006091	62	0.014
protein complex subunit organization	GO:0071822	302	0.013
regulation of ion transport	GO:0043269	245	0.013
cellular response to glucocorticoid stimulus	GO:0071385	68	0.013
synaptic vesicle endocytosis	GO:0048488	4	0.013
isoprenoid metabolic process	GO:0006720	45	0.013
protein phosphorylation	GO:0006468	345	0.013
nucleoside phosphate catabolic process	GO:1901292	140	0.013
protein complex assembly	GO:0006461	263	0.013
regulation of respiratory system process	GO:0044065	1	0.013
purine ribonucleoside metabolic process	GO:0046128	168	0.013
divalent inorganic cation transport	GO:0072511	134	0.013
dna replication	GO:0006260	37	0.013
anion transport	GO:0006820	178	0.013
cell cycle	GO:0007049	101	0.013
positive regulation of dendrite development	GO:1900006	35	0.013
dna metabolic process	GO:0006259	96	0.013
positive regulation of cellular biosynthetic process	GO:0031328	295	0.013
vesicle localization	GO:0051648	33	0.013
regulation of dendrite development	GO:0050773	59	0.013
regulation of cell projection organization	GO:0031344	175	0.013
ribonucleotide catabolic process	GO:0009261	136	0.013
positive regulation of cell death	GO:0010942	184	0.013
steroid metabolic process	GO:0008202	73	0.013
hair cell differentiation	GO:0035315	2	0.012
tissue development	GO:0009888	252	0.012
synapse maturation	GO:0060074	5	0.012
protein transport	GO:0015031	132	0.012
response to transition metal nanoparticle	GO:1990267	122	0.012
locomotion	GO:0040011	237	0.012
male mating behavior	GO:0060179	3	0.012
organelle fusion	GO:0048284	17	0.012
rna biosynthetic process	GO:0032774	380	0.012
regulation of nucleotide metabolic process	GO:0006140	117	0.012
response to cesium ion	GO:0010164	2	0.012
single organism intracellular transport	GO:1902582	166	0.012
purine ribonucleotide metabolic process	GO:0009150	227	0.012
protein oligomerization	GO:0051259	191	0.012
nucleoside monophosphate metabolic process	GO:0009123	93	0.012
spindle organization	GO:0007051	2	0.012
organonitrogen compound catabolic process	GO:1901565	179	0.012
regulation of cellular amino acid metabolic process	GO:0006521	2	0.012
protein targeting	GO:0006605	61	0.012
ionotropic glutamate receptor signaling pathway	GO:0035235	34	0.012
intracellular signal transduction	GO:0035556	314	0.012
guanosine containing compound metabolic process	GO:1901068	74	0.012
synaptic vesicle priming	GO:0016082	4	0.012
cellular response to cgmp	GO:0071321	2	0.012
regulation of vascular smooth muscle contraction	GO:0003056	3	0.012
axis specification	GO:0009798	4	0.012
cell cycle process	GO:0022402	57	0.012
nucleoside triphosphate metabolic process	GO:0009141	144	0.011
membrane fusion	GO:0061025	26	0.011
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	28	0.011
cellular protein localization	GO:0034613	122	0.011
response to calcium ion	GO:0051592	59	0.011
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	41	0.011
response to inorganic substance	GO:0010035	377	0.011
purine nucleotide catabolic process	GO:0006195	136	0.011
gtp metabolic process	GO:0046039	72	0.011
regulation of transmembrane transport	GO:0034762	122	0.011
single organism cellular localization	GO:1902580	102	0.011
negative regulation of catalytic activity	GO:0043086	103	0.011
purine nucleoside catabolic process	GO:0006152	124	0.011
response to testosterone	GO:0033574	55	0.011
amine metabolic process	GO:0009308	38	0.011
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
guanosine containing compound catabolic process	GO:1901069	71	0.011
inner ear morphogenesis	GO:0042472	1	0.011
detection of external stimulus	GO:0009581	13	0.011
catabolic process	GO:0009056	351	0.011
purine nucleoside metabolic process	GO:0042278	169	0.011
cellular polysaccharide metabolic process	GO:0044264	23	0.011
growth	GO:0040007	165	0.011
long chain fatty acid metabolic process	GO:0001676	32	0.011
hormone metabolic process	GO:0042445	69	0.011
regulation of glucose transport	GO:0010827	18	0.011
hindbrain morphogenesis	GO:0021575	2	0.011
olfactory behavior	GO:0042048	2	0.011
positive regulation of catalytic activity	GO:0043085	184	0.011
negative regulation of signaling	GO:0023057	157	0.011
cerebellar purkinje cell layer morphogenesis	GO:0021692	1	0.011
positive regulation of neurogenesis	GO:0050769	165	0.011
urea cycle	GO:0000050	5	0.011
positive regulation of biosynthetic process	GO:0009891	319	0.011
response to zinc ion	GO:0010043	39	0.011
nucleoside metabolic process	GO:0009116	179	0.010
regulation of cell cycle	GO:0051726	73	0.010
regulation of apoptotic process	GO:0042981	335	0.010
regulation of hormone secretion	GO:0046883	106	0.010
neuron cell cell adhesion	GO:0007158	3	0.010
organelle localization	GO:0051640	55	0.010
receptor mediated endocytosis	GO:0006898	42	0.010
cofactor metabolic process	GO:0051186	95	0.010
cytoplasmic transport	GO:0016482	115	0.010

Faah disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.058
nervous system disease	DOID:863	0.058
central nervous system disease	DOID:331	0.058
brain disease	DOID:936	0.013

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network