IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Prp2l1

proline rich protein 2-like 1

(Aliases: PRP-2,PRP,Prp-5)

Entrez: 287750
RGD: 735046

Process Predictions
Disease Predictions

Prp2l1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
inorganic ion transmembrane transport	GO:0098660	229	0.184
transmembrane transport	GO:0055085	412	0.163
response to organophosphorus	GO:0046683	102	0.150
response to nutrient levels	GO:0031667	370	0.146
cation transmembrane transport	GO:0098655	263	0.143
carboxylic acid metabolic process	GO:0019752	289	0.117
ion transmembrane transport	GO:0034220	365	0.117
cellular component assembly	GO:0022607	360	0.104
organic substance catabolic process	GO:1901575	316	0.101
response to purine containing compound	GO:0014074	126	0.098
organic acid metabolic process	GO:0006082	292	0.096
regulation of phosphorylation	GO:0042325	248	0.095
anion transport	GO:0006820	178	0.094
single organism catabolic process	GO:0044712	283	0.093
regulation of signal transduction	GO:0009966	318	0.090
regulation of cellular protein metabolic process	GO:0032268	267	0.082
heart contraction	GO:0060047	57	0.078
reproductive process	GO:0022414	372	0.072
cell projection organization	GO:0030030	302	0.068
cellular amino acid metabolic process	GO:0006520	107	0.066
circulatory system process	GO:0003013	183	0.065
cellular amine metabolic process	GO:0044106	38	0.063
regulation of nucleic acid templated transcription	GO:1903506	380	0.060
nucleic acid templated transcription	GO:0097659	379	0.060
response to hypoxia	GO:0001666	231	0.058
development of primary sexual characteristics	GO:0045137	107	0.057
regulation of cellular amino acid metabolic process	GO:0006521	2	0.055
cellular ketone metabolic process	GO:0042180	51	0.055
regulation of transcription dna templated	GO:0006355	374	0.053
amine metabolic process	GO:0009308	38	0.052
regulation of cellular amine metabolic process	GO:0033238	8	0.052
response to fungicide	GO:0060992	20	0.051
oxoacid metabolic process	GO:0043436	290	0.050
cellular response to endogenous stimulus	GO:0071495	377	0.050
protein complex biogenesis	GO:0070271	263	0.049
rna metabolic process	GO:0016070	406	0.049
synaptic transmission	GO:0007268	235	0.046
nitrogen compound transport	GO:0071705	229	0.046
neuron apoptotic process	GO:0051402	88	0.046
cellular response to oxygen containing compound	GO:1901701	386	0.046
metal ion transport	GO:0030001	289	0.045
neuron development	GO:0048666	286	0.045
negative regulation of vascular permeability	GO:0043116	3	0.043
macromolecular complex assembly	GO:0065003	273	0.043
response to decreased oxygen levels	GO:0036293	237	0.042
positive regulation of phosphorylation	GO:0042327	177	0.042
steroid biosynthetic process	GO:0006694	48	0.042
motor neuron axon guidance	GO:0008045	1	0.041
cellular component movement	GO:0006928	248	0.041
negative regulation of metabolic process	GO:0009892	331	0.041
positive regulation of cellular amine metabolic process	GO:0033240	3	0.040
positive regulation of biosynthetic process	GO:0009891	319	0.040
protein complex assembly	GO:0006461	263	0.040
lipid biosynthetic process	GO:0008610	128	0.038
cellular response to organic cyclic compound	GO:0071407	202	0.038
regulation of neuron death	GO:1901214	115	0.038
response to nicotine	GO:0035094	51	0.037
positive regulation of cell death	GO:0010942	184	0.037
brain development	GO:0007420	247	0.037
regulation of protein modification process	GO:0031399	194	0.037
regulation of kinase activity	GO:0043549	117	0.037
regulation of multicellular organismal development	GO:2000026	376	0.036
regulation of phosphorus metabolic process	GO:0051174	349	0.036
gonad development	GO:0008406	104	0.036
neuron death	GO:0070997	127	0.036
response to nutrient	GO:0007584	248	0.035
positive regulation of catalytic activity	GO:0043085	184	0.034
catabolic process	GO:0009056	351	0.034
central nervous system development	GO:0007417	311	0.033
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.033
regulation of mapk cascade	GO:0043408	116	0.033
regulation of cellular ketone metabolic process	GO:0010565	27	0.033
anion transmembrane transport	GO:0098656	77	0.032
response to extracellular stimulus	GO:0009991	380	0.032
rna biosynthetic process	GO:0032774	380	0.032
organic hydroxy compound transport	GO:0015850	77	0.032
positive regulation of phosphorus metabolic process	GO:0010562	262	0.031
positive regulation of programmed cell death	GO:0043068	157	0.031
blood circulation	GO:0008015	183	0.031
regulation of rna metabolic process	GO:0051252	391	0.031
organic anion transport	GO:0015711	132	0.031
protein phosphorylation	GO:0006468	345	0.030
nucleobase containing small molecule metabolic process	GO:0055086	316	0.030
secretion	GO:0046903	307	0.029
carbohydrate derivative metabolic process	GO:1901135	346	0.029
reproduction	GO:0000003	245	0.029
positive regulation of phosphate metabolic process	GO:0045937	262	0.029
regulation of rna biosynthetic process	GO:2001141	381	0.029
regulation of membrane potential	GO:0042391	110	0.029
programmed cell death	GO:0012501	392	0.028
response to cytokine	GO:0034097	215	0.028
inorganic cation transmembrane transport	GO:0098662	202	0.028
organic hydroxy compound metabolic process	GO:1901615	115	0.028
cellular catabolic process	GO:0044248	295	0.028
regulation of protein metabolic process	GO:0051246	289	0.028
carboxylic acid transport	GO:0046942	115	0.028
protein complex subunit organization	GO:0071822	302	0.028
protein homooligomerization	GO:0051260	91	0.027
positive regulation of cell development	GO:0010720	176	0.027
regulation of neuron apoptotic process	GO:0043523	83	0.027
developmental process involved in reproduction	GO:0003006	159	0.027
response to growth factor	GO:0070848	189	0.026
localization of cell	GO:0051674	202	0.026
vascular process in circulatory system	GO:0003018	96	0.026
monocarboxylic acid metabolic process	GO:0032787	152	0.026
organophosphate metabolic process	GO:0019637	370	0.026
oxidation reduction process	GO:0055114	304	0.026
macromolecular complex subunit organization	GO:0043933	339	0.026
negative regulation of macromolecule metabolic process	GO:0010605	260	0.025
regulation of catalytic activity	GO:0050790	304	0.025
regulation of ion transport	GO:0043269	245	0.025
regulation of blood vessel size	GO:0050880	89	0.024
neuron projection development	GO:0031175	273	0.024
regulation of phosphate metabolic process	GO:0019220	349	0.023
amino acid transport	GO:0006865	70	0.023
cellular component biogenesis	GO:0044085	368	0.023
negative regulation of response to stimulus	GO:0048585	155	0.023
protein oligomerization	GO:0051259	191	0.023
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.023
regulation of cellular component movement	GO:0051270	150	0.022
negative regulation of cellular metabolic process	GO:0031324	281	0.022
choline transport	GO:0015871	4	0.022
striated muscle contraction	GO:0006941	44	0.022
sex differentiation	GO:0007548	113	0.022
transcription dna templated	GO:0006351	377	0.022
cellular response to alcohol	GO:0097306	87	0.021
positive regulation of molecular function	GO:0044093	230	0.021
negative regulation of cellular protein metabolic process	GO:0032269	106	0.021
nucleoside phosphate metabolic process	GO:0006753	283	0.021
second messenger mediated signaling	GO:0019932	51	0.021
organic acid transport	GO:0015849	116	0.021
heart process	GO:0003015	57	0.021
single organism biosynthetic process	GO:0044711	342	0.020
establishment of protein localization	GO:0045184	141	0.020
action potential	GO:0001508	54	0.020
male gonad development	GO:0008584	59	0.020
regulation of cell migration	GO:0030334	128	0.020
protein heterooligomerization	GO:0051291	89	0.020
cellular response to nitrogen compound	GO:1901699	210	0.020
cell morphogenesis	GO:0000902	142	0.019
reproductive system development	GO:0061458	128	0.019
organic cyclic compound catabolic process	GO:1901361	175	0.019
regulation of body fluid levels	GO:0050878	90	0.019
protein targeting	GO:0006605	61	0.019
single organism intracellular transport	GO:1902582	166	0.019
proteolysis	GO:0006508	175	0.019
small gtpase mediated signal transduction	GO:0007264	36	0.019
regulation of hydrolase activity	GO:0051336	143	0.019
aromatic compound catabolic process	GO:0019439	168	0.018
intracellular transport	GO:0046907	185	0.018
single organism behavior	GO:0044708	130	0.018
regulation of heart contraction	GO:0008016	48	0.018
alpha amino acid metabolic process	GO:1901605	71	0.018
locomotion	GO:0040011	237	0.018
purine containing compound metabolic process	GO:0072521	253	0.018
neurological system process	GO:0050877	219	0.018
male sex differentiation	GO:0046661	64	0.018
positive regulation of mapk cascade	GO:0043410	92	0.018
positive regulation of blood circulation	GO:1903524	65	0.018
heterocycle catabolic process	GO:0046700	167	0.017
positive regulation of protein metabolic process	GO:0051247	178	0.017
behavior	GO:0007610	205	0.017
regulation of locomotion	GO:0040012	148	0.017
single organism reproductive process	GO:0044702	297	0.016
regulation of transmembrane transport	GO:0034762	122	0.016
cerebellar purkinje cell layer development	GO:0021680	2	0.016
positive regulation of protein modification process	GO:0031401	142	0.016
intracellular protein transport	GO:0006886	79	0.016
positive regulation of neuron death	GO:1901216	43	0.016
neuron differentiation	GO:0030182	368	0.016
regulation of protein phosphorylation	GO:0001932	183	0.016
regulation of calcium ion transport	GO:0051924	77	0.016
cellular response to external stimulus	GO:0071496	118	0.015
positive regulation of cellular protein metabolic process	GO:0032270	167	0.015
negative regulation of signal transduction	GO:0009968	83	0.015
response to estradiol	GO:0032355	164	0.015
cardiovascular system development	GO:0072358	134	0.015
multicellular organismal signaling	GO:0035637	44	0.015
negative regulation of gene expression	GO:0010629	199	0.015
cellular response to growth factor stimulus	GO:0071363	162	0.015
membrane organization	GO:0061024	94	0.015
negative regulation of protein metabolic process	GO:0051248	114	0.015
cation transport	GO:0006812	382	0.015
ras protein signal transduction	GO:0007265	29	0.014
response to camp	GO:0051591	91	0.014
cellular component morphogenesis	GO:0032989	155	0.014
purine nucleotide catabolic process	GO:0006195	136	0.014
regulation of intracellular transport	GO:0032386	65	0.014
nucleoside phosphate catabolic process	GO:1901292	140	0.014
positive regulation of ion transport	GO:0043270	94	0.014
response to corticosteroid	GO:0031960	235	0.014
organonitrogen compound catabolic process	GO:1901565	179	0.014
regulation of ion transmembrane transport	GO:0034765	121	0.014
response to ketone	GO:1901654	182	0.014
defense response	GO:0006952	194	0.014
prepulse inhibition	GO:0060134	1	0.014
positive regulation of intracellular signal transduction	GO:1902533	138	0.014
nucleoside triphosphate metabolic process	GO:0009141	144	0.014
sympathetic nervous system development	GO:0048485	1	0.014
head development	GO:0060322	247	0.014
regulation of nucleobase containing compound transport	GO:0032239	1	0.014
cell cell signaling	GO:0007267	335	0.014
memory	GO:0007613	54	0.014
regulation of protein kinase activity	GO:0045859	105	0.014
embryonic pattern specification	GO:0009880	1	0.013
peptidyl tyrosine phosphorylation	GO:0018108	72	0.013
purine containing compound catabolic process	GO:0072523	138	0.013
response to oxygen levels	GO:0070482	265	0.013
regulation of tube size	GO:0035150	89	0.013
ribonucleotide catabolic process	GO:0009261	136	0.013
development of primary male sexual characteristics	GO:0046546	59	0.013
regulation of respiratory system process	GO:0044065	1	0.013
regulation of cell development	GO:0060284	263	0.013
organic acid catabolic process	GO:0016054	49	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.013
regulation of homeostatic process	GO:0032844	101	0.013
neuron projection morphogenesis	GO:0048812	122	0.013
response to glucocorticoid	GO:0051384	223	0.013
response to alkaloid	GO:0043279	132	0.013
carbohydrate derivative catabolic process	GO:1901136	147	0.013
cellular macromolecule localization	GO:0070727	122	0.013
peptidyl amino acid modification	GO:0018193	126	0.013
positive regulation of cellular component organization	GO:0051130	200	0.013
positive regulation of nervous system development	GO:0051962	178	0.013
nucleobase containing compound catabolic process	GO:0034655	152	0.012
glycosyl compound catabolic process	GO:1901658	126	0.012
protein autophosphorylation	GO:0046777	66	0.012
positive regulation of transcription dna templated	GO:0045893	197	0.012
muscle system process	GO:0003012	115	0.012
regulation of nucleotide biosynthetic process	GO:0030808	47	0.012
cellular modified amino acid metabolic process	GO:0006575	61	0.012
multi organism reproductive process	GO:0044703	262	0.012
negative regulation of rna metabolic process	GO:0051253	123	0.012
anatomical structure morphogenesis	GO:0009653	298	0.012
learning or memory	GO:0007611	90	0.012
regulation of respiratory gaseous exchange by neurological system process	GO:0002087	1	0.012
positive regulation of developmental process	GO:0051094	283	0.012
negative regulation of cell proliferation	GO:0008285	119	0.012
response to biotic stimulus	GO:0009607	226	0.012
regulation of cardiac muscle contraction	GO:0055117	17	0.012
axis specification	GO:0009798	4	0.012
multicellular organismal reproductive process	GO:0048609	233	0.012
transcription from rna polymerase ii promoter	GO:0006366	252	0.011
autonomic nervous system development	GO:0048483	3	0.011
g protein coupled receptor signaling pathway	GO:0007186	242	0.011
circadian rhythm	GO:0007623	88	0.011
glycosyl compound metabolic process	GO:1901657	182	0.011
single organism cellular localization	GO:1902580	102	0.011
regulation of skeletal muscle tissue regeneration	GO:0043416	2	0.011
reproductive behavior	GO:0019098	10	0.011
activation of mapkkk activity	GO:0000185	1	0.011
monovalent inorganic cation transport	GO:0015672	172	0.011
vesicle mediated transport	GO:0016192	181	0.011
positive regulation of cellular component biogenesis	GO:0044089	55	0.011
defense response to gram negative bacterium	GO:0050829	3	0.011
response to activity	GO:0014823	73	0.011
nucleotide metabolic process	GO:0009117	279	0.011
potassium ion transport	GO:0006813	97	0.011
regulation of cellular localization	GO:0060341	263	0.011
protein localization	GO:0008104	191	0.011
positive regulation of lipid catabolic process	GO:0050996	4	0.011
apoptotic process	GO:0006915	381	0.011
negative regulation of homeostatic process	GO:0032845	47	0.011
regulation of intracellular signal transduction	GO:1902531	218	0.011
vitamin d metabolic process	GO:0042359	4	0.011
sexual reproduction	GO:0019953	148	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
positive regulation of apoptotic process	GO:0043065	154	0.011
cell migration	GO:0016477	197	0.011
response to osmotic stress	GO:0006970	42	0.011
negative regulation of cellular biosynthetic process	GO:0031327	161	0.011
ribonucleotide metabolic process	GO:0009259	231	0.011
purine nucleotide metabolic process	GO:0006163	229	0.011
synaptic growth at neuromuscular junction	GO:0051124	1	0.011
ribose phosphate metabolic process	GO:0019693	235	0.011
monocarboxylic acid transport	GO:0015718	52	0.011
urogenital system development	GO:0001655	78	0.010
response to hexose	GO:0009746	144	0.010
regulation of nervous system development	GO:0051960	264	0.010
cardiac muscle contraction	GO:0060048	27	0.010
positive regulation of response to stimulus	GO:0048584	285	0.010
positive regulation of transport	GO:0051050	245	0.010
negative regulation of proteolysis	GO:0045861	41	0.010
camp metabolic process	GO:0046058	63	0.010
regulation of cell differentiation	GO:0045595	320	0.010
multicellular organism reproduction	GO:0032504	233	0.010
progesterone biosynthetic process	GO:0006701	3	0.010
regulation of nephron tubule epithelial cell differentiation	GO:0072182	1	0.010
transmission of nerve impulse	GO:0019226	42	0.010
negative regulation of cell communication	GO:0010648	158	0.010
regulation of molecular function	GO:0065009	398	0.010
multi multicellular organism process	GO:0044706	138	0.010
cytoplasmic transport	GO:0016482	115	0.010

Prp2l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
urinary system disease	DOID:18	0.057
disease of anatomical entity	DOID:7	0.057
nervous system disease	DOID:863	0.015
central nervous system disease	DOID:331	0.011

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