IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Vtcn1

V-set domain containing T cell activation inhibitor 1

(Aliases: RGD1311204)

Entrez: 295322
RGD: 1311204
Ensembl: ENSRNOG00000015279
UniProtKB: Q501W4

Process Predictions
Disease Predictions

Vtcn1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to lipopolysaccharide	GO:0032496	191	0.381
response to molecule of bacterial origin	GO:0002237	194	0.117
response to biotic stimulus	GO:0009607	226	0.115	Mouse
response to peptide	GO:1901652	292	0.083
response to bacterium	GO:0009617	200	0.082
cell cell signaling	GO:0007267	335	0.081
response to external biotic stimulus	GO:0043207	221	0.077	Mouse
wound healing	GO:0042060	122	0.076
regulation of body fluid levels	GO:0050878	90	0.075
amine metabolic process	GO:0009308	38	0.073
response to toxic substance	GO:0009636	133	0.073
single organism biosynthetic process	GO:0044711	342	0.068
response to metal ion	GO:0010038	253	0.067
brain development	GO:0007420	247	0.067
response to acid chemical	GO:0001101	222	0.066
cellular response to lipid	GO:0071396	201	0.066
small molecule biosynthetic process	GO:0044283	124	0.065
tissue development	GO:0009888	252	0.064
anatomical structure morphogenesis	GO:0009653	298	0.064
carboxylic acid metabolic process	GO:0019752	289	0.062
protein complex subunit organization	GO:0071822	302	0.062
head development	GO:0060322	247	0.061
cation homeostasis	GO:0055080	195	0.061
synaptic transmission	GO:0007268	235	0.060
regulation of cell proliferation	GO:0042127	359	0.058	Mouse
response to inorganic substance	GO:0010035	377	0.057
cellular response to oxygen containing compound	GO:1901701	386	0.055
response to interleukin 1	GO:0070555	55	0.053
hepaticobiliary system development	GO:0061008	90	0.052
chemical homeostasis	GO:0048878	292	0.051
fractalkine metabolic process	GO:0050756	3	0.051
response to peptide hormone	GO:0043434	278	0.048
proteolysis	GO:0006508	175	0.047
protein complex assembly	GO:0006461	263	0.046
cellular response to fluid shear stress	GO:0071498	4	0.045
cation transmembrane transport	GO:0098655	263	0.043
response to camp	GO:0051591	91	0.043
organic cyclic compound catabolic process	GO:1901361	175	0.042
cellular response to stress	GO:0033554	269	0.042
circulatory system development	GO:0072359	134	0.041
regulation of response to stress	GO:0080134	126	0.041	Rat
response to purine containing compound	GO:0014074	126	0.040
membrane organization	GO:0061024	94	0.039
female pregnancy	GO:0007565	122	0.039
regulation of system process	GO:0044057	208	0.039
regulation of apoptotic process	GO:0042981	335	0.038
negative regulation of multicellular organismal process	GO:0051241	203	0.037
hormone metabolic process	GO:0042445	69	0.037
homeostatic process	GO:0042592	331	0.037
regulation of catecholamine secretion	GO:0050433	32	0.037
cellular chemical homeostasis	GO:0055082	247	0.037
cardiovascular system development	GO:0072358	134	0.037
protein complex biogenesis	GO:0070271	263	0.036
macromolecular complex assembly	GO:0065003	273	0.036
limb morphogenesis	GO:0035108	4	0.036
positive regulation of transport	GO:0051050	245	0.036	Mouse
cell adhesion	GO:0007155	110	0.036
protein homotrimerization	GO:0070207	15	0.035
regulation of cell differentiation	GO:0045595	320	0.035
positive regulation of gene expression	GO:0010628	244	0.035
response to other organism	GO:0051707	220	0.035	Mouse
rna biosynthetic process	GO:0032774	380	0.035
gland development	GO:0048732	155	0.035
transmembrane transport	GO:0055085	412	0.035
metal ion transport	GO:0030001	289	0.034
positive regulation of signaling	GO:0023056	270	0.034	Rat
response to organophosphorus	GO:0046683	102	0.034
regulation of amine transport	GO:0051952	54	0.034
blood circulation	GO:0008015	183	0.033
nucleic acid templated transcription	GO:0097659	379	0.033
divalent inorganic cation homeostasis	GO:0072507	165	0.032
single organism membrane organization	GO:0044802	74	0.032
cellular response to organonitrogen compound	GO:0071417	197	0.032
macromolecule localization	GO:0033036	252	0.032	Mouse
response to vitamin	GO:0033273	131	0.031
regulation of hormone levels	GO:0010817	187	0.031
cellular ketone metabolic process	GO:0042180	51	0.031
sexual reproduction	GO:0019953	148	0.030
neuron differentiation	GO:0030182	368	0.030
glycosyl compound metabolic process	GO:1901657	182	0.030
organic acid biosynthetic process	GO:0016053	83	0.030
response to nutrient	GO:0007584	248	0.030
response to extracellular stimulus	GO:0009991	380	0.030
organic acid metabolic process	GO:0006082	292	0.030
positive regulation of cell proliferation	GO:0008284	249	0.029	Mouse
nitrogen compound transport	GO:0071705	229	0.029
cellular response to biotic stimulus	GO:0071216	59	0.029
circulatory system process	GO:0003013	183	0.029
single organism reproductive process	GO:0044702	297	0.029
cellular modified amino acid biosynthetic process	GO:0042398	18	0.028
muscle structure development	GO:0061061	87	0.028
biological adhesion	GO:0022610	110	0.028
immune system process	GO:0002376	204	0.028	Mouse Rat
muscle system process	GO:0003012	115	0.028
central nervous system development	GO:0007417	311	0.028
neurological system process	GO:0050877	219	0.027
monovalent inorganic cation transport	GO:0015672	172	0.027
response to alkaloid	GO:0043279	132	0.027
lipid biosynthetic process	GO:0008610	128	0.027
response to estrogen	GO:0043627	232	0.027
single organism catabolic process	GO:0044712	283	0.027
rna metabolic process	GO:0016070	406	0.027
multi organism reproductive process	GO:0044703	262	0.027
ion homeostasis	GO:0050801	212	0.026
cellular component assembly	GO:0022607	360	0.026
response to decreased oxygen levels	GO:0036293	237	0.026
negative regulation of transcription dna templated	GO:0045892	116	0.026
catecholamine transport	GO:0051937	37	0.026
t cell activation	GO:0042110	29	0.026	Mouse
multicellular organism reproduction	GO:0032504	233	0.026
multicellular organismal water homeostasis	GO:0050891	4	0.026
response to radiation	GO:0009314	137	0.025
regulation of protein metabolic process	GO:0051246	289	0.025
positive regulation of biosynthetic process	GO:0009891	319	0.025
neuron projection development	GO:0031175	273	0.025
regulation of protein modification process	GO:0031399	194	0.025
cellular amino acid metabolic process	GO:0006520	107	0.025
cellular ion homeostasis	GO:0006873	184	0.024
epithelium development	GO:0060429	96	0.024
response to calcium ion	GO:0051592	59	0.024
negative regulation of cell proliferation	GO:0008285	119	0.024
estrogen biosynthetic process	GO:0006703	6	0.024
reproductive process	GO:0022414	372	0.024
regulation of rna biosynthetic process	GO:2001141	381	0.024
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.024
cellular component biogenesis	GO:0044085	368	0.024
cellular response to histamine	GO:0071420	3	0.023
response to mechanical stimulus	GO:0009612	134	0.023
signal transduction by phosphorylation	GO:0023014	144	0.023
epithelial cell proliferation	GO:0050673	54	0.023
transcription dna templated	GO:0006351	377	0.023
alpha amino acid metabolic process	GO:1901605	71	0.023
cellular response to peptide	GO:1901653	133	0.022
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.022
cellular homeostasis	GO:0019725	252	0.022
inorganic cation transmembrane transport	GO:0098662	202	0.022
cellular response to lipopolysaccharide	GO:0071222	55	0.022
gamete generation	GO:0007276	124	0.022
positive regulation of cellular biosynthetic process	GO:0031328	295	0.022
positive regulation of rna metabolic process	GO:0051254	203	0.022
macromolecular complex subunit organization	GO:0043933	339	0.022
multicellular organismal reproductive process	GO:0048609	233	0.022
organic substance catabolic process	GO:1901575	316	0.022
cellular catabolic process	GO:0044248	295	0.021
response to wounding	GO:0009611	254	0.021
response to estradiol	GO:0032355	164	0.021
cellular response to inorganic substance	GO:0071241	65	0.021
apoptotic process	GO:0006915	381	0.021
cellular response to reactive oxygen species	GO:0034614	55	0.021
ion transmembrane transport	GO:0034220	365	0.021
regulation of synaptic transmission	GO:0050804	141	0.021
regulation of response to wounding	GO:1903034	69	0.021
tongue morphogenesis	GO:0043587	3	0.021
response to monosaccharide	GO:0034284	159	0.021
response to corticosteroid	GO:0031960	235	0.021
rhythmic process	GO:0048511	156	0.020
multi multicellular organism process	GO:0044706	138	0.020
catecholamine secretion	GO:0050432	33	0.020
sodium ion homeostasis	GO:0055078	23	0.020
metal ion homeostasis	GO:0055065	186	0.020
organic hydroxy compound transport	GO:0015850	77	0.020
oxoacid metabolic process	GO:0043436	290	0.020
cellular response to abiotic stimulus	GO:0071214	85	0.019
protein phosphorylation	GO:0006468	345	0.019
insecticide metabolic process	GO:0017143	4	0.019
renal system process	GO:0003014	40	0.019
response to nutrient levels	GO:0031667	370	0.019
negative regulation of macromolecule metabolic process	GO:0010605	260	0.019
vasculature development	GO:0001944	70	0.019
regulation of molecular function	GO:0065009	398	0.019
forebrain development	GO:0030900	98	0.019
negative regulation of cell death	GO:0060548	229	0.018
cellular response to steroid hormone stimulus	GO:0071383	93	0.018
protein oligomerization	GO:0051259	191	0.018
transcription from rna polymerase ii promoter	GO:0006366	252	0.018
heart process	GO:0003015	57	0.018
positive regulation of amine transport	GO:0051954	26	0.018
positive regulation of wound healing	GO:0090303	6	0.018
response to reactive oxygen species	GO:0000302	120	0.018
steroid biosynthetic process	GO:0006694	48	0.018
purine containing compound metabolic process	GO:0072521	253	0.018
cellular response to external stimulus	GO:0071496	118	0.018
regulation of epithelial cell proliferation	GO:0050678	49	0.018
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.018
cellular hormone metabolic process	GO:0034754	49	0.017
cellular response to nitrogen compound	GO:1901699	210	0.017
divalent inorganic cation transport	GO:0072511	134	0.017
response to oxidative stress	GO:0006979	186	0.017
multicellular organismal signaling	GO:0035637	44	0.017
defense response	GO:0006952	194	0.017
cellular amine metabolic process	GO:0044106	38	0.017
cellular response to molecule of bacterial origin	GO:0071219	56	0.017
c21 steroid hormone biosynthetic process	GO:0006700	10	0.017
regulation of cellular amine metabolic process	GO:0033238	8	0.017
immune response	GO:0006955	104	0.017
regulation of intracellular signal transduction	GO:1902531	218	0.017
regulation of cellular protein metabolic process	GO:0032268	267	0.017
potassium ion transport	GO:0006813	97	0.016
amine transport	GO:0015837	57	0.016
tube development	GO:0035295	89	0.016
positive regulation of cellular component organization	GO:0051130	200	0.016
appendage morphogenesis	GO:0035107	4	0.016
regulation of cell activation	GO:0050865	50	0.016	Mouse
positive regulation of ion transport	GO:0043270	94	0.016
defense response to gram positive bacterium	GO:0050830	2	0.016
circadian rhythm	GO:0007623	88	0.016
regulation of anatomical structure morphogenesis	GO:0022603	141	0.016
positive regulation of cellular amine metabolic process	GO:0033240	3	0.016
intracellular signal transduction	GO:0035556	314	0.016
regulation of cellular amino acid metabolic process	GO:0006521	2	0.016
cellular response to oxidative stress	GO:0034599	76	0.016
catabolic process	GO:0009056	351	0.016
signal release	GO:0023061	145	0.016
single organism intracellular transport	GO:1902582	166	0.015
response to mineralocorticoid	GO:0051385	49	0.015
hepatocyte proliferation	GO:0072574	3	0.015
calcium ion homeostasis	GO:0055074	162	0.015
cellular response to alcohol	GO:0097306	87	0.015
aging	GO:0007568	241	0.015
response to hydrogen peroxide	GO:0042542	89	0.015
defense response to gram negative bacterium	GO:0050829	3	0.015
positive regulation of secretion	GO:0051047	140	0.015	Mouse
regulation of membrane potential	GO:0042391	110	0.015
embryonic limb morphogenesis	GO:0030326	4	0.015
cellular response to organic cyclic compound	GO:0071407	202	0.015
regulation of secretion	GO:0051046	224	0.015	Mouse
positive regulation of cellular protein metabolic process	GO:0032270	167	0.015
positive regulation of protein metabolic process	GO:0051247	178	0.015
cation transport	GO:0006812	382	0.015
cellular response to metal ion	GO:0071248	55	0.015
regulation of lipid biosynthetic process	GO:0046890	38	0.015
regulation of cell development	GO:0060284	263	0.015
regulation of programmed cell death	GO:0043067	341	0.015
phthalate metabolic process	GO:0018963	8	0.015
regulation of mesenchymal cell proliferation	GO:0010464	4	0.015
regulation of blood pressure	GO:0008217	83	0.014
regulation of blood circulation	GO:1903522	110	0.014
positive regulation of phosphorylation	GO:0042327	177	0.014
multicellular organism growth	GO:0035264	1	0.014
ovulation	GO:0030728	17	0.014
neuron death	GO:0070997	127	0.014
positive regulation of multicellular organismal process	GO:0051240	387	0.014	Mouse
heart contraction	GO:0060047	57	0.014
carboxylic acid biosynthetic process	GO:0046394	83	0.014
chromosome segregation	GO:0007059	2	0.014
reproduction	GO:0000003	245	0.014
response to glucocorticoid	GO:0051384	223	0.014
response to fungicide	GO:0060992	20	0.014
androgen biosynthetic process	GO:0006702	10	0.014
cellular response to luteinizing hormone stimulus	GO:0071373	5	0.014
cellular macromolecule localization	GO:0070727	122	0.013
positive regulation of cell activation	GO:0050867	34	0.013	Mouse
embryonic appendage morphogenesis	GO:0035113	4	0.013
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.013
response to hyperoxia	GO:0055093	45	0.013
cellular cation homeostasis	GO:0030003	180	0.013
regulation of multicellular organismal development	GO:2000026	376	0.013
cellular protein localization	GO:0034613	122	0.013
gonad development	GO:0008406	104	0.013
development of primary sexual characteristics	GO:0045137	107	0.013
carbohydrate homeostasis	GO:0033500	75	0.013
response to glucose	GO:0009749	136	0.013
response to cytokine	GO:0034097	215	0.013
glucose homeostasis	GO:0042593	75	0.013
innate immune response	GO:0045087	35	0.013
positive regulation of catecholamine secretion	GO:0033605	13	0.013
response to transition metal nanoparticle	GO:1990267	122	0.013
developmental process involved in reproduction	GO:0003006	159	0.013
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	3	0.013
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.013
leukocyte activation	GO:0045321	76	0.013	Mouse
male mating behavior	GO:0060179	3	0.013
salivary gland morphogenesis	GO:0007435	1	0.013
positive regulation of mapk cascade	GO:0043410	92	0.012
dicarboxylic acid metabolic process	GO:0043648	42	0.012
regulation of smoothened signaling pathway	GO:0008589	2	0.012
positive regulation of cell communication	GO:0010647	271	0.012	Rat
transmission of nerve impulse	GO:0019226	42	0.012
cellular response to interleukin 1	GO:0071347	37	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.012
monocarboxylic acid biosynthetic process	GO:0072330	48	0.012
negative regulation of gene expression	GO:0010629	199	0.012
regulation of vasculature development	GO:1901342	44	0.012
anterior posterior pattern specification	GO:0009952	1	0.012
cellular response to corticosteroid stimulus	GO:0071384	69	0.012
purine nucleoside metabolic process	GO:0042278	169	0.012
response to increased oxygen levels	GO:0036296	45	0.012
negative regulation of cell communication	GO:0010648	158	0.012
regulation of vasoconstriction	GO:0019229	44	0.012
cell activation	GO:0001775	97	0.012	Mouse
response to hexose	GO:0009746	144	0.012
response to oxygen levels	GO:0070482	265	0.012
glycosyl compound catabolic process	GO:1901658	126	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.011
organ morphogenesis	GO:0009887	75	0.011
calcitriol biosynthetic process from calciol	GO:0036378	2	0.011
response to hypoxia	GO:0001666	231	0.011
regulation of canonical wnt signaling pathway	GO:0060828	4	0.011
positive regulation of catalytic activity	GO:0043085	184	0.011
cellular response to peptide hormone stimulus	GO:0071375	120	0.011
ras protein signal transduction	GO:0007265	29	0.011
organelle localization	GO:0051640	55	0.011
epithelial cell proliferation involved in liver morphogenesis	GO:0072575	3	0.011
cellular macromolecular complex assembly	GO:0034622	58	0.011
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.011
regulation of cell adhesion	GO:0030155	52	0.011
cell projection organization	GO:0030030	302	0.011
organonitrogen compound catabolic process	GO:1901565	179	0.011
progesterone metabolic process	GO:0042448	8	0.011
growth	GO:0040007	165	0.011
male gamete generation	GO:0048232	99	0.011
regulation of excretion	GO:0044062	21	0.011
positive regulation of cell death	GO:0010942	184	0.011
negative regulation of developmental process	GO:0051093	125	0.011
neuron development	GO:0048666	286	0.011
regulation of transcription dna templated	GO:0006355	374	0.011
positive regulation of developmental process	GO:0051094	283	0.011
spermatogenesis	GO:0007283	99	0.011
muscle tissue development	GO:0060537	58	0.011
nucleoside metabolic process	GO:0009116	179	0.011
chemokine metabolic process	GO:0050755	3	0.011
response to temperature stimulus	GO:0009266	94	0.011
lipid metabolic process	GO:0006629	283	0.011
positive regulation of programmed cell death	GO:0043068	157	0.010
response to dexamethasone	GO:0071548	49	0.010
positive regulation of rna biosynthetic process	GO:1902680	197	0.010
localization of cell	GO:0051674	202	0.010
blood coagulation	GO:0007596	26	0.010
secretion by tissue	GO:0032941	37	0.010
positive regulation of protein phosphorylation	GO:0001934	135	0.010
positive regulation of blood circulation	GO:1903524	65	0.010
myosin filament assembly	GO:0031034	1	0.010
programmed cell death	GO:0012501	392	0.010

Vtcn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.025
disease of anatomical entity	DOID:7	0.025
lower respiratory tract disease	DOID:0050161	0.016
respiratory system disease	DOID:1579	0.016
nervous system disease	DOID:863	0.011
disease of cellular proliferation	DOID:14566	0.011
cancer	DOID:162	0.011
muscular disease	DOID:0080000	0.011
organ system cancer	DOID:0050686	0.010

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