Rattus norvegicus

24 known processes

Slco1a4

solute carrier organic anion transporter family, member 1a4

(Aliases: Slc21a5,Oatp2)

Slco1a4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lauric acid metabolic processGO:004825240.261
exogenous drug catabolic processGO:004273810.182
cellular lipid metabolic processGO:00442552080.180
drug catabolic processGO:004273710.176
nitrogen compound transportGO:00717052290.167
organic anion transportGO:00157111320.151
alkaloid metabolic processGO:000982030.149
response to metal ionGO:00100382530.137
regulation of amino acid transportGO:0051955250.120
response to triglycerideGO:003401430.117
drug transmembrane transportGO:0006855130.114
response to testosteroneGO:0033574550.110
choline transportGO:001587140.108
behaviorGO:00076102050.102
halogenated hydrocarbon metabolic processGO:004219740.091
monocarboxylic acid metabolic processGO:00327871520.091
organonitrogen compound biosynthetic processGO:19015661670.086
oxoacid metabolic processGO:00434362900.086
carboxylic acid metabolic processGO:00197522890.085
amino acid transmembrane transportGO:0003333330.084
lipid metabolic processGO:00066292830.083
drug metabolic processGO:0017144110.083
transmembrane transportGO:00550854120.079
macromolecule localizationGO:00330362520.076
response to transition metal nanoparticleGO:19902671220.073
organic acid metabolic processGO:00060822920.073
fluorene metabolic processGO:001891710.072
extracellular matrix constituent secretionGO:007027840.071
cellular catabolic processGO:00442482950.068
glycerolipid metabolic processGO:0046486670.068
monocarboxylic acid transportGO:0015718520.067
response to cesium ionGO:001016420.064
organic hydroxy compound metabolic processGO:19016151150.061
positive regulation of transportGO:00510502450.059
response to toxic substanceGO:00096361330.058
response to acid chemicalGO:00011012220.055
single organism biosynthetic processGO:00447113420.054
amine metabolic processGO:0009308380.052
regulation of secretionGO:00510462240.052
oligopeptide transportGO:000685740.052
amino acid transportGO:0006865700.052
organic acid transportGO:00158491160.051
long chain fatty acid metabolic processGO:0001676320.051
positive regulation of multicellular organismal processGO:00512403870.049
regulation of cellular component organizationGO:00511283680.049
toxin metabolic processGO:000940490.048
carboxylic acid transportGO:00469421150.047
chlorinated hydrocarbon metabolic processGO:004219640.047
regulation of secretion by cellGO:19035302080.047
toxin catabolic processGO:000940710.046
response to xenobiotic stimulusGO:0009410230.046
epoxygenase p450 pathwayGO:001937310.046
response to ketoneGO:19016541820.046
cellular amine metabolic processGO:0044106380.046
trichloroethylene metabolic processGO:001897910.043
multi organism reproductive processGO:00447032620.043
ion transmembrane transportGO:00342203650.042
anion transmembrane transportGO:0098656770.042
response to inorganic substanceGO:00100353770.041
response to other organismGO:00517072200.040
oxidative demethylationGO:007098920.038
blood circulationGO:00080151830.038
cellular homeostasisGO:00197252520.037
dicarboxylic acid transportGO:0006835340.035
reproductive processGO:00224143720.035
benzene containing compound metabolic processGO:0042537220.035
liver developmentGO:0001889900.034
sulfur compound transportGO:007234880.034
cellular amino acid metabolic processGO:00065201070.034
regulation of ion transportGO:00432692450.034
vitamin transportGO:0051180140.033
linoleic acid metabolic processGO:004365140.033
homeostatic processGO:00425923310.033
synaptic transmissionGO:00072682350.032
cation transportGO:00068123820.032
small molecule biosynthetic processGO:00442831240.032
negative regulation of developmental processGO:00510931250.031
amide transportGO:00428861050.031
chemical homeostasisGO:00488782920.030
response to peptide hormoneGO:00434342780.030
organic cyclic compound catabolic processGO:19013611750.030
cellular response to hormone stimulusGO:00328702470.030
protein localizationGO:00081041910.030
anion transportGO:00068201780.030
regulation of gamma aminobutyric acid secretionGO:001405260.029
response to hypoxiaGO:00016662310.029
calcitriol biosynthetic process from calciolGO:003637820.029
macromolecular complex subunit organizationGO:00439333390.029
modified amino acid transportGO:0072337120.029
insecticide metabolic processGO:001714340.028
terpenoid metabolic processGO:0006721370.028
fatty acid metabolic processGO:0006631990.028
macromolecular complex assemblyGO:00650032730.028
negative regulation of serine type peptidase activityGO:190257210.028
response to decreased oxygen levelsGO:00362932370.028
secretion by cellGO:00329402480.028
catabolic processGO:00090563510.027
naphthalene metabolic processGO:001893120.027
response to extracellular stimulusGO:00099913800.027
organonitrogen compound catabolic processGO:19015651790.027
cellular sodium ion homeostasisGO:000688340.027
single organism behaviorGO:00447081300.026
positive regulation of secretion by cellGO:19035321280.026
nicotine metabolic processGO:001893310.026
dopamine metabolic processGO:0042417120.026
vesicle mediated transportGO:00161921810.026
regulation of tube sizeGO:0035150890.026
response to sulfur dioxideGO:001047730.026
small molecule catabolic processGO:0044282590.025
regulation of serine type peptidase activityGO:190257110.025
alcohol metabolic processGO:0006066770.025
multicellular organism growthGO:003526410.024
cellular ion homeostasisGO:00068731840.024
angiotensin mediated drinking behaviorGO:000305120.024
regulation of apoptotic processGO:00429813350.024
secretionGO:00469033070.024
response to external biotic stimulusGO:00432072210.024
isoprenoid metabolic processGO:0006720450.024
neurological system processGO:00508772190.024
cellular component assemblyGO:00226073600.024
regulation of cellular localizationGO:00603412630.023
xenobiotic metabolic processGO:0006805190.023
response to ethanolGO:00454711620.023
head developmentGO:00603222470.023
response to oxidative stressGO:00069791860.023
negative regulation of serine type endopeptidase activityGO:190000410.022
response to peptideGO:19016522920.022
circulatory system processGO:00030131830.022
regulation of programmed cell deathGO:00430673410.022
response to vitamin b6GO:003451610.022
cellular biogenic amine catabolic processGO:004240290.022
cellular chemical homeostasisGO:00550822470.022
negative regulation of cellular metabolic processGO:00313242810.022
cytolysisGO:001983540.021
regulation of nervous system developmentGO:00519602640.021
regulation of cellular amine metabolic processGO:003323880.021
positive regulation of secretionGO:00510471400.021
response to glucocorticoidGO:00513842230.021
vasoconstrictionGO:0042310540.021
cellular response to lipidGO:00713962010.021
response to ddtGO:004668010.021
amine catabolic processGO:000931090.020
organelle organizationGO:00069962660.020
organic hydroxy compound biosynthetic processGO:1901617510.020
response to insecticideGO:0017085210.020
intestinal absorptionGO:005089230.020
regulation of neurotransmitter levelsGO:0001505420.020
positive regulation of apoptotic processGO:00430651540.020
negative regulation of nervous system developmentGO:0051961790.020
cellular cation homeostasisGO:00300031800.020
response to ionizing radiationGO:0010212590.020
regulation of blood pressureGO:0008217830.020
protein oligomerizationGO:00512591910.019
response to oxygen levelsGO:00704822650.019
g protein coupled receptor signaling pathwayGO:00071862420.019
metal ion transportGO:00300012890.019
single organism organelle organizationGO:19025891800.019
regulation of multicellular organismal developmentGO:20000263760.019
cation homeostasisGO:00550801950.019
cellular component biogenesisGO:00440853680.019
phenylpropanoid metabolic processGO:000969850.019
phenol containing compound biosynthetic processGO:004618990.019
regulation of cellular amino acid metabolic processGO:000652120.018
glutathione transportGO:003463520.018
regenerationGO:00310991630.018
unsaturated fatty acid metabolic processGO:0033559390.018
regulation of rna biosynthetic processGO:20011413810.018
neuron differentiationGO:00301823680.018
regulation of hormone levelsGO:00108171870.017
negative regulation of metabolic processGO:00098923310.017
hormone transportGO:00099141210.017
lipid biosynthetic processGO:00086101280.017
positive regulation of nervous system developmentGO:00519621780.017
regulation of amine transportGO:0051952540.017
response to estrogenGO:00436272320.017
regulation of anion transportGO:0044070430.017
protein transportGO:00150311320.017
cerebellar granule cell precursor proliferationGO:002193010.017
regulation of serine type endopeptidase activityGO:190000310.017
lipid localizationGO:0010876620.017
secondary metabolite catabolic processGO:009048710.017
fatty acid derivative metabolic processGO:1901568380.017
central nervous system developmentGO:00074173110.016
positive regulation of nitrogen compound metabolic processGO:00511733340.016
apoptotic processGO:00069153810.016
regulation of reactive oxygen species biosynthetic processGO:190342650.016
positive regulation of programmed cell deathGO:00430681570.016
organic substance catabolic processGO:19015753160.016
reactive nitrogen species metabolic processGO:200105710.016
response to fatty acidGO:0070542650.016
metanephric comma shaped body morphogenesisGO:007227820.016
regulation of immune responseGO:0050776550.016
multicellular organism reproductionGO:00325042330.016
regulation of organic acid transportGO:0032890350.016
defense response to gram negative bacteriumGO:005082930.016
regulation of phosphate metabolic processGO:00192203490.015
cellular ketone metabolic processGO:0042180510.015
organic hydroxy compound transportGO:0015850770.015
cellular biogenic amine metabolic processGO:0006576300.015
diterpenoid metabolic processGO:0016101330.015
regulation of neurogenesisGO:00507672470.015
cell proliferation in external granule layerGO:002192410.015
cellular metal ion homeostasisGO:00068751720.015
cellular response to organic cyclic compoundGO:00714072020.015
drug transportGO:0015893180.015
beta alanine metabolic processGO:001948230.015
positive regulation of developmental processGO:00510942830.015
transcription dna templatedGO:00063513770.015
regulation of cellular protein metabolic processGO:00322682670.015
brain developmentGO:00074202470.015
carboxylic acid biosynthetic processGO:0046394830.015
bile acid and bile salt transportGO:0015721120.014
hepaticobiliary system developmentGO:0061008900.014
response to mercury ionGO:0046689150.014
organophosphate metabolic processGO:00196373700.014
immune system processGO:00023762040.014
heterocycle catabolic processGO:00467001670.014
response to vitamin dGO:0033280340.014
negative regulation of macromolecule metabolic processGO:00106052600.014
catechol containing compound metabolic processGO:0009712190.014
negative regulation of cell communicationGO:00106481580.014
reproductionGO:00000032450.014
medium chain fatty acid metabolic processGO:005179150.014
response to calcium ionGO:0051592590.014
carbohydrate derivative metabolic processGO:19011353460.014
renin angiotensin regulation of aldosterone productionGO:000201830.014
pyridine containing compound metabolic processGO:0072524320.013
response to lead ionGO:0010288330.013
regulation of immune system processGO:00026821230.013
cellular nitrogen compound catabolic processGO:00442701630.013
organic acid catabolic processGO:0016054490.013
glycoside transportGO:190165620.013
response to nutrient levelsGO:00316673700.013
regulation of extracellular matrix constituent secretionGO:000333020.013
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.013
cellular response to stressGO:00335542690.013
regulation of blood vessel sizeGO:0050880890.013
antibiotic transportGO:004289120.013
intracellular transportGO:00469071850.013
triglyceride metabolic processGO:0006641210.013
secretion by tissueGO:0032941370.013
response to methanolGO:003398610.013
circulatory system developmentGO:00723591340.012
protein complex assemblyGO:00064612630.012
rna biosynthetic processGO:00327743800.012
cellular response to xenobiotic stimulusGO:0071466190.012
regulation of cell differentiationGO:00455953200.012
response to purine containing compoundGO:00140741260.012
gland developmentGO:00487321550.012
transmission of nerve impulseGO:0019226420.012
localization of cellGO:00516742020.012
regulation of anatomical structure sizeGO:00900661350.012
tonic smooth muscle contractionGO:001482040.012
oxidation reduction processGO:00551143040.012
protein complex biogenesisGO:00702712630.012
regulation of protein metabolic processGO:00512462890.012
glycogen metabolic processGO:0005977230.012
organic cation transportGO:0015695110.012
odontogenesisGO:0042476320.012
transcription from rna polymerase ii promoterGO:00063662520.012
aromatic amino acid family catabolic processGO:000907470.012
multicellular organismal reproductive processGO:00486092330.012
organic acid biosynthetic processGO:0016053830.012
tripeptide transportGO:004293920.012
sexual reproductionGO:00199531480.012
response to carbohydrateGO:00097431830.011
regulation of cellular ketone metabolic processGO:0010565270.011
nucleotide metabolic processGO:00091172790.011
indole containing compound metabolic processGO:0042430110.011
nucleobase containing small molecule metabolic processGO:00550863160.011
protein complex subunit organizationGO:00718223020.011
aromatic amino acid family metabolic processGO:000907290.011
catechol containing compound biosynthetic processGO:000971390.011
negative regulation of cell differentiationGO:0045596990.011
response to alkaloidGO:00432791320.011
positive regulation of blood circulationGO:1903524650.011
regulation of immunoglobulin productionGO:000263740.011
indolalkylamine metabolic processGO:000658650.011
positive regulation of signalingGO:00230562700.011
cellular hormone metabolic processGO:0034754490.011
positive regulation of long term synaptic potentiationGO:190027340.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
lipid transportGO:0006869610.011
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.011
carbohydrate metabolic processGO:00059751300.011
growthGO:00400071650.011
response to cadmium ionGO:0046686350.011
negative regulation of protein metabolic processGO:00512481140.010
gamma aminobutyric acid secretionGO:001405160.010
negative regulation of molecular functionGO:00440921330.010
positive regulation of extracellular matrix organizationGO:190305540.010
cellular response to corticosteroid stimulusGO:0071384690.010
reactive oxygen species biosynthetic processGO:190340980.010
positive regulation of amine transportGO:0051954260.010
naphthalene containing compound metabolic processGO:009042020.010
single organism catabolic processGO:00447122830.010
protein homooligomerizationGO:0051260910.010
developmental process involved in reproductionGO:00030061590.010
neurotransmitter uptakeGO:000150430.010

Slco1a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.132
cardiovascular system diseaseDOID:128700.132
vascular diseaseDOID:17800.132
artery diseaseDOID:005082800.044
hypertensionDOID:1076300.044
essential hypertensionDOID:1082500.015
nervous system diseaseDOID:86300.015
inherited metabolic disorderDOID:65500.010
disease of metabolismDOID:001466700.010