Rattus norvegicus

85 known processes

Ppp1ca

protein phosphatase 1, catalytic subunit, alpha isoform

Ppp1ca biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecular complex subunit organizationGO:00439333390.303
positive regulation of cell deathGO:00109421840.301
Mouse
positive regulation of programmed cell deathGO:00430681570.234
Mouse
intracellular signal transductionGO:00355563140.185
cell cycle checkpointGO:000007520.183
positive regulation of response to stimulusGO:00485842850.173
Mouse
regulation of programmed cell deathGO:00430673410.162
Mouse
cell growthGO:00160491040.157
regulation of signal transductionGO:00099663180.153
Mouse
protein localizationGO:00081041910.144
regulation of apoptotic processGO:00429813350.133
Mouse
intracellular transportGO:00469071850.122
macromolecule localizationGO:00330362520.121
regulation of catalytic activityGO:00507903040.121
regulation of intracellular signal transductionGO:19025312180.119
sorbitol biosynthetic processGO:000606110.118
apoptotic processGO:00069153810.116
Mouse
cellular response to endogenous stimulusGO:00714953770.113
positive regulation of apoptotic processGO:00430651540.113
Mouse
phenol containing compound metabolic processGO:0018958300.110
programmed cell deathGO:00125013920.109
Mouse
regulation of neuron deathGO:19012141150.108
positive regulation of cell communicationGO:00106472710.107
Mouse
response to ketoneGO:19016541820.102
cell type specific apoptotic processGO:00972851340.101
cellular component biogenesisGO:00440853680.100
negative regulation of cellular metabolic processGO:00313242810.099
positive regulation of signalingGO:00230562700.097
Mouse
cell cycleGO:00070491010.093
organic substance catabolic processGO:19015753160.092
multi organism reproductive processGO:00447032620.090
developmental growthGO:00485891000.088
positive regulation of cell proliferationGO:00082842490.085
macromolecular complex assemblyGO:00650032730.082
cell migrationGO:00164771970.081
homeostatic processGO:00425923310.081
regulation of cell proliferationGO:00421273590.081
organophosphate metabolic processGO:00196373700.080
immune responseGO:00069551040.080
positive regulation of developmental processGO:00510942830.080
multicellular organismal reproductive processGO:00486092330.079
positive regulation of protein phosphorylationGO:00019341350.077
dna metabolic processGO:0006259960.076
multicellular organism reproductionGO:00325042330.073
locomotionGO:00400112370.071
regulation of neuron apoptotic processGO:0043523830.071
cellular response to oxygen containing compoundGO:19017013860.071
neuron projection developmentGO:00311752730.070
nucleic acid templated transcriptionGO:00976593790.069
regulation of transcription dna templatedGO:00063553740.068
taxisGO:0042330670.068
carbohydrate metabolic processGO:00059751300.067
regulation of protein localizationGO:0032880810.066
organophosphate biosynthetic processGO:00904071430.065
negative regulation of nitrogen compound metabolic processGO:00511721610.063
regulation of nucleic acid templated transcriptionGO:19035063800.063
regulation of cardiac muscle tissue growthGO:0055021120.063
cytoskeleton organizationGO:00070101110.062
positive regulation of protein metabolic processGO:00512471780.062
positive regulation of neuron deathGO:1901216430.062
cellular amino acid metabolic processGO:00065201070.062
reproductionGO:00000032450.061
cellular protein localizationGO:00346131220.061
muscle system processGO:00030121150.061
regulation of cell differentiationGO:00455953200.061
cellular response to stressGO:00335542690.057
nucleotide metabolic processGO:00091172790.057
positive regulation of transcription dna templatedGO:00458931970.057
protein transportGO:00150311320.056
protein complex subunit organizationGO:00718223020.056
regulation of phosphorylationGO:00423252480.055
regulation of growthGO:00400081050.055
positive regulation of rna biosynthetic processGO:19026801970.054
negative regulation of neuron deathGO:1901215690.053
hematopoietic progenitor cell differentiationGO:000224420.053
regulation of multicellular organismal developmentGO:20000263760.053
rna biosynthetic processGO:00327743800.051
cellular macromolecular complex assemblyGO:0034622580.051
cellular process involved in reproduction in multicellular organismGO:0022412350.051
response to hydrogen peroxideGO:0042542890.050
regulation of molecular functionGO:00650093980.050
cellular component assemblyGO:00226073600.049
single organism organelle organizationGO:19025891800.048
positive regulation of molecular functionGO:00440932300.047
transcription from rna polymerase ii promoterGO:00063662520.047
regulation of phosphate metabolic processGO:00192203490.047
reproductive processGO:00224143720.046
norepinephrine metabolic processGO:004241530.045
response to peptideGO:19016522920.044
neuron deathGO:00709971270.044
purine containing compound metabolic processGO:00725212530.044
regulation of organelle organizationGO:0033043800.043
positive regulation of protein modification processGO:00314011420.043
cellular catabolic processGO:00442482950.043
sorbitol metabolic processGO:000606010.042
jak stat cascadeGO:0007259260.041
positive regulation of intracellular signal transductionGO:19025331380.041
amine metabolic processGO:0009308380.040
cell cycle processGO:0022402570.040
negative regulation of cell deathGO:00605482290.040
behaviorGO:00076102050.040
urogenital system developmentGO:0001655780.039
response to reactive oxygen speciesGO:00003021200.038
regulation of cellular localizationGO:00603412630.038
catabolic processGO:00090563510.038
regulation of cellular protein metabolic processGO:00322682670.038
positive regulation of transportGO:00510502450.038
rna metabolic processGO:00160704060.037
head developmentGO:00603222470.037
transcription dna templatedGO:00063513770.037
response to oxidative stressGO:00069791860.037
positive regulation of macromolecule biosynthetic processGO:00105572470.037
neurological system processGO:00508772190.036
oxoacid metabolic processGO:00434362900.036
regulation of phosphorus metabolic processGO:00511743490.036
cellular ketone metabolic processGO:0042180510.036
purine nucleoside triphosphate metabolic processGO:00091441410.036
cellular chemical homeostasisGO:00550822470.035
regulation of developmental growthGO:0048638450.035
negative regulation of mitotic cell cycle phase transitionGO:190199130.035
cellular response to peptideGO:19016531330.034
neuron differentiationGO:00301823680.033
ribonucleotide metabolic processGO:00092592310.033
central nervous system developmentGO:00074173110.033
regulation of cellular component organizationGO:00511283680.033
regulation of cell growthGO:0001558850.032
positive regulation of phosphate metabolic processGO:00459372620.032
positive regulation of phosphorus metabolic processGO:00105622620.032
negative regulation of macromolecule metabolic processGO:00106052600.032
positive regulation of nitrogen compound metabolic processGO:00511733340.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
negative regulation of cell cycle phase transitionGO:190198840.031
localization of cellGO:00516742020.031
neuron apoptotic processGO:0051402880.031
organelle organizationGO:00069962660.031
cellular response to growth factor stimulusGO:00713631620.031
microtubule cytoskeleton organizationGO:0000226250.031
collecting duct developmentGO:007204410.030
tissue developmentGO:00098882520.030
Mouse
cellular homeostasisGO:00197252520.030
response to estrogenGO:00436272320.030
single organism behaviorGO:00447081300.030
single organism reproductive processGO:00447022970.030
response to estradiolGO:00323551640.030
purine nucleoside metabolic processGO:00422781690.030
cellular amine metabolic processGO:0044106380.030
carbohydrate derivative metabolic processGO:19011353460.029
protein phosphorylationGO:00064683450.029
single organism carbohydrate metabolic processGO:00447231180.029
heart developmentGO:0007507720.028
regulation of rna biosynthetic processGO:20011413810.028
regulation of cellular amino acid metabolic processGO:000652120.028
response to peptide hormoneGO:00434342780.028
dna integrity checkpointGO:003157020.028
regulation of protein phosphorylationGO:00019321830.028
single organism biosynthetic processGO:00447113420.027
cellular macromolecule localizationGO:00707271220.027
regulation of cellular amine metabolic processGO:003323880.027
negative regulation of metabolic processGO:00098923310.027
cation transportGO:00068123820.027
chemotaxisGO:0006935660.027
mitotic spindle organizationGO:000705220.027
cellular response to ketoneGO:1901655510.027
purine nucleotide metabolic processGO:00061632290.027
negative regulation of programmed cell deathGO:00430691830.026
cellular lipid metabolic processGO:00442552080.026
isoprenoid metabolic processGO:0006720450.026
positive regulation of signal transductionGO:00099671750.026
Mouse
negative regulation of neuron apoptotic processGO:0043524450.026
cellular response to nitrogen compoundGO:19016992100.026
alditol metabolic processGO:001940040.025
response to cytokineGO:00340972150.025
regulation of cellular ketone metabolic processGO:0010565270.025
regulation of anatomical structure sizeGO:00900661350.025
regulation of rna metabolic processGO:00512523910.025
small molecule biosynthetic processGO:00442831240.025
mitotic cell cycle checkpointGO:000709310.025
positive regulation of growthGO:0045927550.025
regulation of protein modification processGO:00313991940.024
cardiovascular system developmentGO:00723581340.024
Zebrafish
renal system developmentGO:0072001670.024
sexual reproductionGO:00199531480.024
cellular component movementGO:00069282480.024
regulation of homeostatic processGO:00328441010.024
organonitrogen compound biosynthetic processGO:19015661670.024
cellular ion homeostasisGO:00068731840.024
organic hydroxy compound metabolic processGO:19016151150.024
purine ribonucleotide metabolic processGO:00091502270.024
response to woundingGO:00096112540.024
negative regulation of molecular functionGO:00440921330.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
regulation of cell migrationGO:00303341280.024
positive regulation of cellular component organizationGO:00511302000.023
microtubule based processGO:0007017360.023
cation homeostasisGO:00550801950.023
response to growth factorGO:00708481890.023
cardiac muscle cell developmentGO:0055013160.023
response to glucocorticoidGO:00513842230.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
protein import into nucleusGO:0006606350.023
response to radiationGO:00093141370.023
Mouse
positive regulation of cell growthGO:0030307440.023
negative regulation of apoptotic processGO:00430661810.022
dephosphorylationGO:0016311980.022
response to metal ionGO:00100382530.022
somatic stem cell divisionGO:004810320.022
cellular protein complex assemblyGO:0043623440.022
carbohydrate derivative catabolic processGO:19011361470.022
brain developmentGO:00074202470.022
mitotic cell cycleGO:0000278490.022
response to alkaloidGO:00432791320.022
organonitrogen compound catabolic processGO:19015651790.022
positive regulation of phosphorylationGO:00423271770.022
guanosine containing compound catabolic processGO:1901069710.022
cell motilityGO:00488702020.022
positive regulation of multicellular organismal processGO:00512403870.022
negative regulation of signalingGO:00230571570.022
carbohydrate derivative biosynthetic processGO:19011371240.021
negative regulation of phosphorus metabolic processGO:0010563800.021
positive regulation of cellular protein metabolic processGO:00322701670.021
synaptic growth at neuromuscular junctionGO:005112410.021
vesicle localizationGO:0051648330.021
inner medullary collecting duct developmentGO:007206110.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
positive regulation of developmental growthGO:0048639290.021
proteolysisGO:00065081750.021
agingGO:00075682410.021
regulation of vesicle mediated transportGO:0060627810.021
developmental process involved in reproductionGO:00030061590.021
multicellular organism growthGO:003526410.021
response to inorganic substanceGO:00100353770.020
nucleoside triphosphate metabolic processGO:00091411440.020
nucleocytoplasmic transportGO:0006913480.020
circulatory system developmentGO:00723591340.020
Zebrafish
membrane organizationGO:0061024940.020
protein ubiquitinationGO:0016567280.020
nucleobase containing small molecule metabolic processGO:00550863160.019
secretionGO:00469033070.019
negative regulation of nucleic acid templated transcriptionGO:19035071170.019
regulation of secretionGO:00510462240.019
growthGO:00400071650.019
regulation of hormone levelsGO:00108171870.019
cellular response to organonitrogen compoundGO:00714171970.018
regulation of hydrolase activityGO:00513361430.018
protein modification by small protein conjugation or removalGO:0070647350.018
camp metabolic processGO:0046058630.018
striated muscle tissue developmentGO:0014706580.018
lipid metabolic processGO:00066292830.018
cellular metal ion homeostasisGO:00068751720.017
retinal metabolic processGO:004257430.017
negative regulation of catalytic activityGO:00430861030.017
carboxylic acid metabolic processGO:00197522890.017
hormone metabolic processGO:0042445690.017
regulation of system processGO:00440572080.017
response to corticosteroidGO:00319602350.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
cardiac cell developmentGO:0055006160.017
ribose phosphate metabolic processGO:00196932350.017
ion transmembrane transportGO:00342203650.017
cytoplasmic transportGO:00164821150.017
cellular response to dna damage stimulusGO:0006974190.016
dna damage checkpointGO:000007720.016
positive regulation of biosynthetic processGO:00098913190.016
axon developmentGO:0061564960.016
phospholipid metabolic processGO:0006644610.016
atp metabolic processGO:0046034720.016
regulation of heart growthGO:0060420120.016
heart morphogenesisGO:000300730.016
regulation of purine nucleotide metabolic processGO:19005421150.016
organic hydroxy compound biosynthetic processGO:1901617510.016
ion homeostasisGO:00508012120.016
regulation of muscle system processGO:0090257790.016
muscle structure developmentGO:0061061870.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
regulation of ion transportGO:00432692450.016
response to acid chemicalGO:00011012220.016
axis specificationGO:000979840.016
chromosome segregationGO:000705920.016
carbohydrate biosynthetic processGO:0016051420.016
regulation of response to external stimulusGO:00321011060.016
cell projection morphogenesisGO:00488581230.016
sequestering of calcium ionGO:005120880.015
regulation of muscle tissue developmentGO:1901861250.015
metal ion transportGO:00300012890.015
regulation of smooth muscle cell proliferationGO:0048660750.015
spermatogenesisGO:0007283990.015
nucleoside metabolic processGO:00091161790.015
hippocampus developmentGO:0021766300.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
Zebrafish
purine ribonucleoside metabolic processGO:00461281680.015
positive regulation of cellular biosynthetic processGO:00313282950.015
gamete generationGO:00072761240.015
tube developmentGO:0035295890.014
Mouse
organic acid metabolic processGO:00060822920.014
establishment of protein localizationGO:00451841410.014
negative regulation of cellular component organizationGO:0051129830.014
positive regulation of muscle organ developmentGO:0048636130.014
lipid storageGO:001991510.014
chemical homeostasisGO:00488782920.014
galactose metabolic processGO:000601240.014
regulation of kinase activityGO:00435491170.014
cellular component morphogenesisGO:00329891550.014
protein autophosphorylationGO:0046777660.014
response to oxygen levelsGO:00704822650.014
negative regulation of signal transductionGO:0009968830.014
regulation of lipid metabolic processGO:0019216680.014
response to amino acidGO:0043200750.014
cardiac muscle tissue growthGO:0055017200.014
cell projection organizationGO:00300303020.014
response to nutrient levelsGO:00316673700.013
peptidyl amino acid modificationGO:00181931260.013
positive regulation of cell developmentGO:00107201760.013
gtp metabolic processGO:0046039720.013
negative regulation of protein metabolic processGO:00512481140.013
regulation of cell developmentGO:00602842630.013
ribonucleoside metabolic processGO:00091191740.013
cell cell signalingGO:00072673350.013
glucose homeostasisGO:0042593750.013
alcohol metabolic processGO:0006066770.013
cell part morphogenesisGO:00329901230.013
phospholipid biosynthetic processGO:0008654290.013
positive regulation of cellular component biogenesisGO:0044089550.013
positive regulation of cell differentiationGO:00455972170.013
regulation of meiotic cell cycleGO:005144530.013
single organism intracellular transportGO:19025821660.013
regulation of cellular component sizeGO:0032535510.013
cellular response to cytokine stimulusGO:00713451270.013
positive regulation of cell growth involved in cardiac muscle cell developmentGO:006105150.013
regulation of organ growthGO:0046620130.013
positive regulation of catalytic activityGO:00430851840.012
heart growthGO:0060419200.012
cation transmembrane transportGO:00986552630.012
g protein coupled receptor signaling pathwayGO:00071862420.012
cellular response to lipidGO:00713962010.012
regulation of immune system processGO:00026821230.012
regulation of locomotionGO:00400121480.012
positive regulation of gene expressionGO:00106282440.012
regulation of cellular component biogenesisGO:0044087860.012
nitrogen compound transportGO:00717052290.012
neuron developmentGO:00486662860.012
organ growthGO:0035265240.012
protein localization to endoplasmic reticulumGO:007097210.012
negative regulation of rna metabolic processGO:00512531230.012
ribonucleoprotein complex subunit organizationGO:007182680.012
regulation of cell projection organizationGO:00313441750.012
gastrulationGO:000736920.012
regulation of nucleotide metabolic processGO:00061401170.012
protein homooligomerizationGO:0051260910.012
hexose metabolic processGO:0019318580.012
axon guidanceGO:0007411240.012
single organism cellular localizationGO:19025801020.012
protein complex biogenesisGO:00702712630.012
locomotory behaviorGO:0007626150.011
protein complex assemblyGO:00064612630.011
cellular response to external stimulusGO:00714961180.011
male sex differentiationGO:0046661640.011
heterocycle catabolic processGO:00467001670.011
inorganic ion transmembrane transportGO:00986602290.011
spindle organizationGO:000705120.011
aromatic compound catabolic processGO:00194391680.011
response to extracellular stimulusGO:00099913800.011
establishment of vesicle localizationGO:0051650310.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
positive regulation of jak stat cascadeGO:0046427190.011
neuron projection guidanceGO:0097485240.011
regulation of neurogenesisGO:00507672470.011
cardiac muscle tissue developmentGO:0048738260.011
organic cyclic compound catabolic processGO:19013611750.010
regulation of cell motilityGO:20001451310.010
cellular aldehyde metabolic processGO:0006081110.010
muscle cell proliferationGO:0033002840.010
regulation of neuron differentiationGO:00456642080.010
regulation of nervous system developmentGO:00519602640.010
kidney developmentGO:0001822670.010
regulation of cell sizeGO:0008361370.010
intracellular protein transportGO:0006886790.010
regulation of cell cycle processGO:0010564310.010
transmembrane transportGO:00550854120.010
nucleoside catabolic processGO:00091641260.010
sensory organ developmentGO:0007423740.010
naphthalene metabolic processGO:001893120.010

Ppp1ca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.018
disease of anatomical entityDOID:700.018
connective tissue diseaseDOID:6500.018
disease of cellular proliferationDOID:1456600.016
benign neoplasmDOID:006007200.016