Rattus norvegicus

6 known processes

Kl

Klotho

Kl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123820.744
cellular divalent inorganic cation homeostasisGO:00725031620.740
response to biotic stimulusGO:00096072260.633
inorganic cation transmembrane transportGO:00986622020.604
organic anion transportGO:00157111320.597
inorganic ion transmembrane transportGO:00986602290.565
transmembrane transportGO:00550854120.555
monovalent inorganic cation transportGO:00156721720.509
nitrogen compound transportGO:00717052290.507
ion transmembrane transportGO:00342203650.504
regulation of cellular localizationGO:00603412630.474
lipid metabolic processGO:00066292830.471
cellular ion homeostasisGO:00068731840.454
regulation of ion transportGO:00432692450.450
carboxylic acid transportGO:00469421150.415
positive regulation of secretionGO:00510471400.382
anion transportGO:00068201780.375
positive regulation of cytosolic calcium ion concentrationGO:00072041220.372
central nervous system developmentGO:00074173110.348
cytosolic calcium ion homeostasisGO:00514801400.348
organic hydroxy compound metabolic processGO:19016151150.339
response to temperature stimulusGO:0009266940.326
behaviorGO:00076102050.323
amino acid transportGO:0006865700.315
ion homeostasisGO:00508012120.306
metal ion transportGO:00300012890.302
oxoacid metabolic processGO:00434362900.297
monocarboxylic acid transportGO:0015718520.290
single organism behaviorGO:00447081300.277
cellular response to endogenous stimulusGO:00714953770.270
response to ammonium ionGO:0060359710.261
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.249
cellular metal ion homeostasisGO:00068751720.245
calcium ion homeostasisGO:00550741620.239
anion transmembrane transportGO:0098656770.229
reproductive processGO:00224143720.226
carboxylic acid metabolic processGO:00197522890.222
organic acid transportGO:00158491160.212
response to estrogenGO:00436272320.208
Rat
response to bacteriumGO:00096172000.204
sodium ion transportGO:0006814820.204
response to glucocorticoidGO:00513842230.204
regulation of secretionGO:00510462240.200
cation homeostasisGO:00550801950.199
response to toxic substanceGO:00096361330.198
divalent inorganic cation homeostasisGO:00725071650.197
brain developmentGO:00074202470.188
response to alkaloidGO:00432791320.185
cellular response to organic cyclic compoundGO:00714072020.182
response to corticosteroidGO:00319602350.181
response to nutrient levelsGO:00316673700.179
Rat
cellular chemical homeostasisGO:00550822470.179
response to external biotic stimulusGO:00432072210.178
regulation of amine transportGO:0051952540.177
regulation of secretion by cellGO:19035302080.177
cation transmembrane transportGO:00986552630.173
chemical homeostasisGO:00488782920.172
negative regulation of ion transportGO:0043271510.172
kidney developmentGO:0001822670.170
acid secretionGO:0046717480.167
regulation of glutamate secretionGO:0014048170.167
regulation of phosphorus metabolic processGO:00511743490.166
tissue developmentGO:00098882520.165
Human
metal ion homeostasisGO:00550651860.163
organic acid metabolic processGO:00060822920.155
positive regulation of multicellular organismal processGO:00512403870.151
Human
g protein coupled receptor signaling pathwayGO:00071862420.151
protein phosphorylationGO:00064683450.145
cellular response to oxygen containing compoundGO:19017013860.144
head developmentGO:00603222470.144
positive regulation of synaptic transmissionGO:0050806620.141
regulation of cell proliferationGO:00421273590.139
regulation of metal ion transportGO:00109591180.138
inflammatory responseGO:00069541500.138
cellular ketone metabolic processGO:0042180510.132
response to estradiolGO:00323551640.129
regulation of system processGO:00440572080.128
regulation of saliva secretionGO:004687730.127
phasic smooth muscle contractionGO:001482130.126
camera type eye developmentGO:0043010480.125
response to inorganic substanceGO:00100353770.125
Rat
cellular calcium ion homeostasisGO:00068741600.122
cellular cation homeostasisGO:00300031800.120
secretion by cellGO:00329402480.119
positive regulation of cell communicationGO:00106472710.117
hormone transportGO:00099141210.115
regulation of response to external stimulusGO:00321011060.115
response to ethanolGO:00454711620.113
Rat
response to extracellular stimulusGO:00099913800.111
Rat
localization of cellGO:00516742020.110
tube developmentGO:0035295890.110
development of primary female sexual characteristicsGO:0046545560.109
amine metabolic processGO:0009308380.109
sodium ion transmembrane transportGO:0035725670.108
regulation of rna metabolic processGO:00512523910.107
positive regulation of secretion by cellGO:19035321280.107
negative regulation of multicellular organismal processGO:00512412030.107
cellular homeostasisGO:00197252520.106
calcitriol biosynthetic process from calciolGO:003637820.106
regulation of cellular amine metabolic processGO:003323880.106
calcium ion transportGO:00068161310.103
ovulation cycle processGO:0022602500.101
blood circulationGO:00080151830.101
defense responseGO:00069521940.099
neurological system processGO:00508772190.098
homeostatic processGO:00425923310.098
learning or memoryGO:0007611900.097
response to other organismGO:00517072200.096
response to lipopolysaccharideGO:00324961910.095
response to cocaineGO:0042220390.095
lipid localizationGO:0010876620.094
dicarboxylic acid transportGO:0006835340.094
small molecule biosynthetic processGO:00442831240.094
organic acid biosynthetic processGO:0016053830.093
positive regulation of long term synaptic potentiationGO:190027340.093
developmental process involved in reproductionGO:00030061590.093
positive regulation of developmental processGO:00510942830.092
Human
positive regulation of protein phosphorylationGO:00019341350.091
lipid transportGO:0006869610.091
ossificationGO:0001503700.091
Human
negative regulation of cell deathGO:00605482290.090
positive regulation of phosphorus metabolic processGO:00105622620.090
rna biosynthetic processGO:00327743800.089
regulation of synaptic transmissionGO:00508041410.089
secretionGO:00469033070.088
agingGO:00075682410.088
Human
positive regulation of signalingGO:00230562700.088
mesonephros developmentGO:0001823140.087
negative regulation of transportGO:00510511360.087
cellular response to stressGO:00335542690.086
regulation of cellular ketone metabolic processGO:0010565270.085
positive regulation of leukocyte proliferationGO:0070665200.084
cell motilityGO:00488702020.084
amine transportGO:0015837570.083
lipid biosynthetic processGO:00086101280.081
circulatory system processGO:00030131830.079
sensory organ developmentGO:0007423740.078
regulation of transcription dna templatedGO:00063553740.078
amino acid transmembrane transportGO:0003333330.077
hormone mediated signaling pathwayGO:0009755230.076
neuron deathGO:00709971270.075
signal transduction by phosphorylationGO:00230141440.074
cellular amino acid metabolic processGO:00065201070.074
response to growth factorGO:00708481890.073
heart processGO:0003015570.073
response to acid chemicalGO:00011012220.071
cellular component movementGO:00069282480.070
reproductionGO:00000032450.069
multicellular organism reproductionGO:00325042330.069
learningGO:0007612330.069
protein complex subunit organizationGO:00718223020.069
cellular response to hormone stimulusGO:00328702470.069
cell cell signalingGO:00072673350.068
intracellular signal transductionGO:00355563140.068
response to woundingGO:00096112540.068
forebrain developmentGO:0030900980.068
positive regulation of phosphorylationGO:00423271770.068
positive regulation of response to stimulusGO:00485842850.067
regulation of intracellular signal transductionGO:19025312180.066
rhythmic processGO:00485111560.066
fatty acid metabolic processGO:0006631990.065
cellular amine metabolic processGO:0044106380.065
regulation of growthGO:00400081050.064
anatomical structure formation involved in morphogenesisGO:0048646830.064
positive regulation of signal transductionGO:00099671750.064
potassium ion transportGO:0006813970.064
response to cytokineGO:00340972150.063
cellular lipid metabolic processGO:00442552080.063
telencephalon developmentGO:0021537620.063
epithelial cell proliferationGO:0050673540.063
negative regulation of signalingGO:00230571570.063
organonitrogen compound biosynthetic processGO:19015661670.063
response to heatGO:0009408600.063
divalent metal ion transportGO:00708381320.063
memoryGO:0007613540.063
development of primary sexual characteristicsGO:00451371070.062
organelle organizationGO:00069962660.062
glycerolipid metabolic processGO:0046486670.062
regulation of cellular amino acid metabolic processGO:000652120.062
positive regulation of mapk cascadeGO:0043410920.062
hormone secretionGO:00468791150.062
organic hydroxy compound transportGO:0015850770.061
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.061
phenol containing compound metabolic processGO:0018958300.061
mesonephric epithelium developmentGO:0072163140.061
positive regulation of cell migrationGO:0030335960.061
regenerationGO:00310991630.060
regulation of cell differentiationGO:00455953200.060
urinary tract smooth muscle contractionGO:001484840.060
positive regulation of nucleic acid templated transcriptionGO:19035081970.060
immune system processGO:00023762040.059
lymphocyte activationGO:0046649430.059
intracellular transportGO:00469071850.058
positive regulation of cell proliferationGO:00082842490.058
regulation of multicellular organismal developmentGO:20000263760.058
Human
positive regulation of lymphocyte proliferationGO:0050671200.058
synaptic transmission gabaergicGO:0051932220.058
multi multicellular organism processGO:00447061380.057
positive regulation of transportGO:00510502450.057
embryonic skeletal system developmentGO:004870630.057
alcohol metabolic processGO:0006066770.057
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.057
cellular response to lipidGO:00713962010.056
multicellular organismal reproductive processGO:00486092330.056
locomotionGO:00400112370.056
nephron morphogenesisGO:0072028130.055
regulation of ossificationGO:0030278320.055
Human
associative learningGO:0008306190.054
regulation of phosphate metabolic processGO:00192203490.054
sensory perceptionGO:00076001010.054
monocarboxylic acid metabolic processGO:00327871520.054
positive regulation of cellular amine metabolic processGO:003324030.053
positive regulation of rna metabolic processGO:00512542030.053
renal system developmentGO:0072001670.053
urogenital system developmentGO:0001655780.053
positive regulation of cellular component organizationGO:00511302000.053
regulation of blood circulationGO:19035221100.053
regulation of defense responseGO:0031347680.052
acute inflammatory responseGO:0002526580.052
muscle structure developmentGO:0061061870.052
reproductive system developmentGO:00614581280.052
divalent inorganic cation transportGO:00725111340.052
positive regulation of cellular biosynthetic processGO:00313282950.052
regulation of phosphorylationGO:00423252480.052
regulation of cellular component organizationGO:00511283680.051
neuron differentiationGO:00301823680.051
regulation of amino acid transportGO:0051955250.051
cellular component assemblyGO:00226073600.051
muscle cell proliferationGO:0033002840.051
cellular response to steroid hormone stimulusGO:0071383930.051
regulation of kinase activityGO:00435491170.050
macromolecular complex subunit organizationGO:00439333390.050
regulation of neuron deathGO:19012141150.049
cellular response to growth factor stimulusGO:00713631620.049
steroid metabolic processGO:0008202730.049
cell type specific apoptotic processGO:00972851340.049
regulation of apoptotic processGO:00429813350.049
cell migrationGO:00164771970.048
negative regulation of cell developmentGO:0010721820.048
multicellular organism growthGO:003526410.047
cytoskeleton organizationGO:00070101110.047
regulation of response to stressGO:00801341260.047
positive regulation of saliva secretionGO:004687830.047
ureteric bud developmentGO:0001657140.046
negative regulation of molecular functionGO:00440921330.046
organic hydroxy compound biosynthetic processGO:1901617510.046
positive regulation of phosphate metabolic processGO:00459372620.046
positive regulation of intracellular signal transductionGO:19025331380.046
regulation of blood pressureGO:0008217830.046
tissue morphogenesisGO:0048729220.045
embryo developmentGO:0009790490.045
regulation of immune system processGO:00026821230.045
leukocyte activationGO:0045321760.045
positive regulation of macromolecule biosynthetic processGO:00105572470.045
regulation of organic acid transportGO:0032890350.045
regulation of hormone levelsGO:00108171870.045
regulation of protein phosphorylationGO:00019321830.045
regulation of homeostatic processGO:00328441010.045
positive regulation of cell differentiationGO:00455972170.044
response to nutrientGO:00075842480.044
Rat
organ morphogenesisGO:0009887750.044
regulation of cellular protein metabolic processGO:00322682670.044
actin filament based processGO:0030029860.044
negative regulation of programmed cell deathGO:00430691830.044
single organism intracellular transportGO:19025821660.043
digestive system processGO:0022600240.043
positive regulation of cellular amino acid metabolic processGO:004576410.043
response to radiationGO:00093141370.043
fear responseGO:004259690.043
regulation of muscle contractionGO:0006937530.043
regulation of adenylate cyclase activityGO:0045761180.043
response to purine containing compoundGO:00140741260.043
peptidyl amino acid modificationGO:00181931260.043
regulation of developmental growthGO:0048638450.043
digestionGO:0007586260.042
salivary gland developmentGO:000743130.042
embryonic skeletal system morphogenesisGO:004870430.042
growthGO:00400071650.042
regulation of cell migrationGO:00303341280.042
response to peptideGO:19016522920.041
nucleic acid templated transcriptionGO:00976593790.041
regulation of neuron differentiationGO:00456642080.041
alpha amino acid biosynthetic processGO:1901607230.041
positive regulation of protein kinase activityGO:0045860730.041
response to hypoxiaGO:00016662310.041
Rat
urinary bladder smooth muscle contractionGO:001483240.041
micturitionGO:006007340.041
response to oxidative stressGO:00069791860.041
multi organism reproductive processGO:00447032620.041
transcription dna templatedGO:00063513770.040
single organism organelle organizationGO:19025891800.040
cytokine productionGO:0001816610.040
anatomical structure morphogenesisGO:00096532980.040
regulation of rna biosynthetic processGO:20011413810.039
negative regulation of cell differentiationGO:0045596990.039
negative regulation of phosphorus metabolic processGO:0010563800.038
molting cycle processGO:002240420.038
amide transportGO:00428861050.038
carbohydrate derivative metabolic processGO:19011353460.038
positive regulation of biosynthetic processGO:00098913190.038
catecholamine transportGO:0051937370.038
rna metabolic processGO:00160704060.037
regulation of molecular functionGO:00650093980.037
peptide transportGO:0015833970.037
cardiovascular system developmentGO:00723581340.037
multicellular organismal homeostasisGO:0048871490.037
developmental growthGO:00485891000.037
secondary alcohol metabolic processGO:190265220.037
metanephric s shaped body morphogenesisGO:007228420.037
response to oxygen levelsGO:00704822650.037
Rat
response to peptide hormoneGO:00434342780.036
synaptic transmissionGO:00072682350.036
sequestering of calcium ionGO:005120880.036
neuron developmentGO:00486662860.036
positive regulation of apoptotic processGO:00430651540.036
negative regulation of organic acid transportGO:0032891140.036
response to mechanical stimulusGO:00096121340.036
alpha amino acid metabolic processGO:1901605710.036
serotonin receptor signaling pathwayGO:0007210100.036
kidney epithelium developmentGO:0072073190.035
negative regulation of phosphate metabolic processGO:0045936800.035
phospholipid metabolic processGO:0006644610.035
response to vitamin dGO:0033280340.035
positive regulation of gene expressionGO:00106282440.035
organic cyclic compound catabolic processGO:19013611750.035
response to hexoseGO:00097461440.035
regulation of epithelial cell proliferationGO:0050678490.035
regulation of transferase activityGO:00513381230.035
positive regulation of rna biosynthetic processGO:19026801970.035
female sex differentiationGO:0046660590.034
cellular catabolic processGO:00442482950.034
negative regulation of amine transportGO:0051953240.034
response to starvationGO:0042594590.034
Rat
cytoplasmic transportGO:00164821150.034
response to ketoneGO:19016541820.034
negative regulation of nitrogen compound metabolic processGO:00511721610.034
dopamine transportGO:0015872180.034
regulation of cytokine productionGO:0001817560.034
single organism reproductive processGO:00447022970.034
response to monosaccharideGO:00342841590.034
organic substance catabolic processGO:19015753160.034
positive regulation of cellular component movementGO:00512721020.034
hair follicle developmentGO:000194220.034
regulation of cell activationGO:0050865500.034
gonad developmentGO:00084061040.033
neuron fate commitmentGO:004866340.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
circadian rhythmGO:0007623880.033
positive regulation of ion transportGO:0043270940.033
regulation of programmed cell deathGO:00430673410.033
negative regulation of response to external stimulusGO:0032102370.033
positive regulation of protein modification processGO:00314011420.033
regulation of cell developmentGO:00602842630.033
regulation of calcium ion transportGO:0051924770.033
regulation of peptide hormone secretionGO:0090276800.033
neuron projection developmentGO:00311752730.033
limbic system developmentGO:0021761380.033
macromolecule localizationGO:00330362520.033
ribonucleotide catabolic processGO:00092611360.033
regulation of smooth muscle cell proliferationGO:0048660750.033
regulation of behaviorGO:0050795610.032
positive regulation of mononuclear cell proliferationGO:0032946200.032
positive regulation of transcription dna templatedGO:00458931970.032
negative regulation of metabolic processGO:00098923310.032
regulation of cellular component biogenesisGO:0044087860.032
saliva secretionGO:004654130.032
neuron neuron synaptic transmissionGO:0007270600.032
cellular response to nitrogen compoundGO:19016992100.032
mapk cascadeGO:00001651400.032
heart contractionGO:0060047570.032
programmed cell deathGO:00125013920.031
negative regulation of cell communicationGO:00106481580.031
dopamine secretionGO:0014046150.031
negative regulation of amino acid transportGO:0051956130.031
regulation of peptide transportGO:0090087870.031
renal system processGO:0003014400.031
regulation of nucleic acid templated transcriptionGO:19035063800.031
positive regulation of organic acid transportGO:0032892220.031
regulation of cyclic nucleotide biosynthetic processGO:0030802450.031
cognitionGO:0050890920.031
angiogenesisGO:0001525530.031
synaptic transmission dopaminergicGO:0001963110.030
cardiac muscle cell proliferationGO:006003860.030
cellular response to extracellular stimulusGO:0031668730.030
regulation of mapk cascadeGO:00434081160.030
positive regulation of transferase activityGO:0051347810.030
regulation of cyclase activityGO:0031279210.030
response to molecule of bacterial originGO:00022371940.030
positive regulation of blood circulationGO:1903524650.030
positive regulation of growthGO:0045927550.030
positive regulation of locomotionGO:00400171020.030
negative regulation of apoptotic processGO:00430661810.030
anterior posterior pattern specificationGO:000995210.030
positive regulation of cell developmentGO:00107201760.030
cellular response to glucocorticoid stimulusGO:0071385680.030
response to decreased oxygen levelsGO:00362932370.029
Rat
response to nicotineGO:0035094510.029
muscle system processGO:00030121150.029
regulation of establishment of protein localizationGO:0070201690.029
regulation of gamma aminobutyric acid secretionGO:001405260.029
signal releaseGO:00230611450.029
cyclic nucleotide metabolic processGO:0009187800.029
single organism biosynthetic processGO:00447113420.029
response to hydrogen peroxideGO:0042542890.029
reproductive structure developmentGO:00486081280.028
regulation of muscle system processGO:0090257790.028
regulation of hormone secretionGO:00468831060.028
ovulation cycleGO:0042698670.028
regulation of protein modification processGO:00313991940.028
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.028
hormone metabolic processGO:0042445690.028
negative regulation of glutamate secretionGO:001405090.028
response to interleukin 15GO:007067240.028
cellular macromolecule localizationGO:00707271220.028
monoamine transportGO:0015844430.028
epithelium developmentGO:0060429960.027
regulation of anion transportGO:0044070430.027
involuntary skeletal muscle contractionGO:000301120.027
gliogenesisGO:0042063930.027
positive regulation of cellular protein metabolic processGO:00322701670.027
embryonic pattern specificationGO:000988010.027
somatostatin receptor signaling pathwayGO:003816940.027
protein oligomerizationGO:00512591910.027
retina morphogenesis in camera type eyeGO:006004210.027
regulation of cell growthGO:0001558850.026
catabolic processGO:00090563510.026
regulation of membrane potentialGO:00423911100.026
cellular response to alcoholGO:0097306870.026
spinal cord developmentGO:0021510270.026
regulation of body fluid levelsGO:0050878900.026
positive regulation of epithelial cell proliferationGO:0050679320.026
gland developmentGO:00487321550.026
inner ear morphogenesisGO:004247210.026
calcium ion transport into cytosolGO:0060402380.026
single organism catabolic processGO:00447122830.026
cell projection organizationGO:00300303020.026
fat soluble vitamin biosynthetic processGO:004236220.026
peristalsisGO:003043220.026
negative regulation of secretionGO:0051048820.026
regulation of the force of heart contraction by chemical signalGO:000305720.025
apoptotic processGO:00069153810.025
protein transportGO:00150311320.025
hyperosmotic responseGO:0006972180.025
regulation of cellular component movementGO:00512701500.025
negative regulation of response to stimulusGO:00485851550.025
organophosphate biosynthetic processGO:00904071430.025
actin filament organizationGO:0007015420.025
appendage morphogenesisGO:003510740.025
cellular component biogenesisGO:00440853680.025
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.025
regulation of protein metabolic processGO:00512462890.025
regulation of protein localizationGO:0032880810.024
ribose phosphate biosynthetic processGO:0046390870.024
muscle contractionGO:0006936880.024
regulation of protein kinase activityGO:00458591050.024
eye morphogenesisGO:004859240.024
positive regulation of cell growthGO:0030307440.024
regulation of cell motilityGO:20001451310.024
regulation of stem cell differentiationGO:200073620.024
sex differentiationGO:00075481130.024
negative regulation of cellular metabolic processGO:00313242810.024
response to carbohydrateGO:00097431830.024
Rat
negative regulation of developmental processGO:00510931250.024
catecholamine secretionGO:0050432330.024
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.024
ribonucleotide biosynthetic processGO:0009260850.024
jak stat cascadeGO:0007259260.024
transcription from rna polymerase ii promoterGO:00063662520.024
positive regulation of nucleobase containing compound metabolic processGO:00459353190.024
reactive oxygen species metabolic processGO:0072593370.023
macromolecular complex assemblyGO:00650032730.023
actin mediated cell contractionGO:0070252120.023
peptidyl tyrosine modificationGO:0018212720.023
regulation of locomotionGO:00400121480.023
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
maintenance of locationGO:0051235170.023
positive regulation of lymphocyte activationGO:0051251250.023
positive regulation of amino acid transportGO:0051957130.023
regulation of cation channel activityGO:2001257230.023
regulation of anatomical structure morphogenesisGO:00226031410.023
positive regulation of programmed cell deathGO:00430681570.023
regulation of signal transductionGO:00099663180.022
sequestering of metal ionGO:005123890.022
cellular response to cytokine stimulusGO:00713451270.022
positive regulation of catalytic activityGO:00430851840.022
response to transition metal nanoparticleGO:19902671220.022
Rat
regulation of lipid metabolic processGO:0019216680.022
actin cytoskeleton organizationGO:0030036730.022
behavioral response to cocaineGO:004814860.022
smooth muscle contractionGO:0006939370.022
nucleotide metabolic processGO:00091172790.022
response to vitaminGO:00332731310.022
leukocyte proliferationGO:0070661290.022
glutamate secretionGO:0014047190.022
negative regulation of defense responseGO:0031348190.022
negative regulation of macromolecule metabolic processGO:00106052600.022
negative regulation of secretion by cellGO:1903531720.022

Kl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036