Rattus norvegicus

39 known processes

Kcna2

potassium voltage-gated channel, shaker-related subfamily, member 2

(Aliases: NGK1,BK2)

Kcna2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component movementGO:00069282480.433
cell cell signalingGO:00072673350.387
protein complex assemblyGO:00064612630.261
cellular response to endogenous stimulusGO:00714953770.233
cation transportGO:00068123820.229
protein heterooligomerizationGO:0051291890.214
nucleic acid templated transcriptionGO:00976593790.208
regulation of multicellular organismal developmentGO:20000263760.207
regulation of system processGO:00440572080.205
calcium ion homeostasisGO:00550741620.202
behaviorGO:00076102050.187
transmembrane transportGO:00550854120.185
response to toxic substanceGO:00096361330.185
monovalent inorganic cation transportGO:00156721720.182
response to lipopolysaccharideGO:00324961910.158
synaptic transmissionGO:00072682350.147
cellular component biogenesisGO:00440853680.147
protein complex biogenesisGO:00702712630.146
cell motilityGO:00488702020.145
inorganic ion transmembrane transportGO:00986602290.144
transcription from rna polymerase ii promoterGO:00063662520.137
response to glucocorticoidGO:00513842230.137
regulation of rna biosynthetic processGO:20011413810.135
regulation of cell developmentGO:00602842630.132
positive regulation of cell proliferationGO:00082842490.127
positive regulation of ion transportGO:0043270940.125
agingGO:00075682410.125
response to mechanical stimulusGO:00096121340.124
regulation of ion transportGO:00432692450.124
metal ion transportGO:00300012890.118
positive regulation of response to stimulusGO:00485842850.117
blood circulationGO:00080151830.115
response to bacteriumGO:00096172000.114
macromolecular complex assemblyGO:00650032730.113
ion homeostasisGO:00508012120.110
cellular chemical homeostasisGO:00550822470.110
cellular response to stressGO:00335542690.108
positive regulation of secretionGO:00510471400.107
cellular response to growth factor stimulusGO:00713631620.105
learning or memoryGO:0007611900.104
heart contractionGO:0060047570.103
positive regulation of signalingGO:00230562700.102
response to inorganic substanceGO:00100353770.102
brain developmentGO:00074202470.101
central nervous system developmentGO:00074173110.101
sodium ion transmembrane transportGO:0035725670.099
single organism behaviorGO:00447081300.098
macromolecular complex subunit organizationGO:00439333390.095
regulation of cell differentiationGO:00455953200.095
locomotionGO:00400112370.095
cellular ion homeostasisGO:00068731840.093
cation homeostasisGO:00550801950.093
response to metal ionGO:00100382530.090
regulation of cellular localizationGO:00603412630.088
anion transportGO:00068201780.088
response to ketoneGO:19016541820.087
sodium ion transportGO:0006814820.084
response to insulinGO:00328681330.084
g protein coupled receptor signaling pathwayGO:00071862420.083
cellular response to oxygen containing compoundGO:19017013860.083
protein complex subunit organizationGO:00718223020.083
cellular response to glucocorticoid stimulusGO:0071385680.082
rna biosynthetic processGO:00327743800.082
homeostatic processGO:00425923310.081
response to ammonium ionGO:0060359710.080
cellular metal ion homeostasisGO:00068751720.079
regulation of neuron projection developmentGO:00109751610.079
heart processGO:0003015570.078
circulatory system processGO:00030131830.078
positive regulation of macromolecule biosynthetic processGO:00105572470.078
cognitionGO:0050890920.075
chemical homeostasisGO:00488782920.074
cellular homeostasisGO:00197252520.074
negative regulation of response to stimulusGO:00485851550.073
localization of cellGO:00516742020.072
neuron developmentGO:00486662860.071
lipid biosynthetic processGO:00086101280.070
positive regulation of developmental processGO:00510942830.070
positive regulation of biosynthetic processGO:00098913190.070
cellular response to nitrogen compoundGO:19016992100.070
intracellular transportGO:00469071850.068
positive regulation of nucleic acid templated transcriptionGO:19035081970.067
regulation of synaptic transmissionGO:00508041410.066
negative regulation of signal transductionGO:0009968830.065
positive regulation of phosphate metabolic processGO:00459372620.064
regulation of nervous system developmentGO:00519602640.063
secretionGO:00469033070.061
positive regulation of multicellular organismal processGO:00512403870.060
regulation of locomotionGO:00400121480.060
metal ion homeostasisGO:00550651860.059
response to estrogenGO:00436272320.059
cellular calcium ion homeostasisGO:00068741600.058
response to carbohydrateGO:00097431830.058
forebrain developmentGO:0030900980.058
cellular component morphogenesisGO:00329891550.057
regulation of anatomical structure morphogenesisGO:00226031410.057
cell migrationGO:00164771970.056
positive regulation of cell differentiationGO:00455972170.055
protein oligomerizationGO:00512591910.055
regulation of cell proliferationGO:00421273590.055
cation transmembrane transportGO:00986552630.055
positive regulation of transcription dna templatedGO:00458931970.054
response to growth factorGO:00708481890.054
ion transmembrane transportGO:00342203650.054
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.053
neuron differentiationGO:00301823680.053
response to alkaloidGO:00432791320.052
rna metabolic processGO:00160704060.051
regulation of rna metabolic processGO:00512523910.051
negative regulation of cell communicationGO:00106481580.051
regulation of catalytic activityGO:00507903040.051
cellular response to organonitrogen compoundGO:00714171970.051
response to estradiolGO:00323551640.050
response to peptide hormoneGO:00434342780.050
regulation of neurogenesisGO:00507672470.049
purine nucleotide biosynthetic processGO:0006164830.049
growthGO:00400071650.049
positive regulation of rna biosynthetic processGO:19026801970.049
response to molecule of bacterial originGO:00022371940.048
cellular carbohydrate metabolic processGO:0044262720.046
cellular response to external stimulusGO:00714961180.046
cellular cation homeostasisGO:00300031800.046
positive regulation of transportGO:00510502450.045
positive regulation of cellular biosynthetic processGO:00313282950.045
multicellular organism reproductionGO:00325042330.045
positive regulation of nucleobase containing compound metabolic processGO:00459353190.045
regenerationGO:00310991630.044
regulation of cell motilityGO:20001451310.044
neuron deathGO:00709971270.044
response to extracellular stimulusGO:00099913800.043
divalent inorganic cation homeostasisGO:00725071650.043
response to campGO:0051591910.043
negative regulation of signalingGO:00230571570.042
regulation of ion homeostasisGO:2000021630.042
negative regulation of multicellular organismal processGO:00512412030.041
cellular amine metabolic processGO:0044106380.041
regulation of membrane potentialGO:00423911100.041
positive regulation of nervous system developmentGO:00519621780.041
response to biotic stimulusGO:00096072260.041
gland developmentGO:00487321550.041
immune responseGO:00069551040.040
immune system processGO:00023762040.040
cellular ketone metabolic processGO:0042180510.040
regulation of secretion by cellGO:19035302080.040
negative regulation of cell deathGO:00605482290.040
feeding behaviorGO:0007631530.039
muscle system processGO:00030121150.039
response to nutrient levelsGO:00316673700.039
regulation of smooth muscle contractionGO:0006940290.039
cardiovascular system developmentGO:00723581340.039
cell projection organizationGO:00300303020.038
positive regulation of secretion by cellGO:19035321280.038
regulation of amine transportGO:0051952540.037
negative regulation of neuron differentiationGO:0045665620.037
positive regulation of cell developmentGO:00107201760.037
telencephalon developmentGO:0021537620.037
negative regulation of rna biosynthetic processGO:19026791180.037
rhythmic processGO:00485111560.037
response to ethanolGO:00454711620.036
negative regulation of programmed cell deathGO:00430691830.036
developmental growthGO:00485891000.036
locomotory exploration behaviorGO:003564110.036
anion transmembrane transportGO:0098656770.036
head developmentGO:00603222470.036
positive regulation of nitrogen compound metabolic processGO:00511733340.036
calcium ion transport into cytosolGO:0060402380.036
regulation of phosphate metabolic processGO:00192203490.035
circulatory system developmentGO:00723591340.035
sequestering of calcium ionGO:005120880.035
action potentialGO:0001508540.035
transcription dna templatedGO:00063513770.035
response to acid chemicalGO:00011012220.035
cellular response to corticosteroid stimulusGO:0071384690.035
regulation of molecular functionGO:00650093980.035
regulation of nucleic acid templated transcriptionGO:19035063800.034
sequestering of metal ionGO:005123890.034
positive regulation of synaptic transmissionGO:0050806620.034
regulation of secretionGO:00510462240.034
regulation of homeostatic processGO:00328441010.034
protein transportGO:00150311320.033
cellular response to hormone stimulusGO:00328702470.033
regulation of sodium ion transportGO:0002028210.032
positive regulation of intracellular signal transductionGO:19025331380.032
neuron projection developmentGO:00311752730.032
regulation of renal sodium excretionGO:0035813200.031
regulation of blood circulationGO:19035221100.031
negative regulation of gene expressionGO:00106291990.031
cytosolic calcium ion homeostasisGO:00514801400.030
grooming behaviorGO:000762540.030
reproductive processGO:00224143720.029
response to peptideGO:19016522920.029
response to oxygen levelsGO:00704822650.029
regulation of transcription from rna polymerase ii promoterGO:00063572340.029
reproductionGO:00000032450.029
regulation of response to external stimulusGO:00321011060.028
peptide secretionGO:0002790860.028
response to decreased oxygen levelsGO:00362932370.028
lipid metabolic processGO:00066292830.028
positive regulation of amine transportGO:0051954260.028
signal releaseGO:00230611450.028
regulation of transcription dna templatedGO:00063553740.028
regulation of blood vessel sizeGO:0050880890.028
negative regulation of developmental processGO:00510931250.028
cellular divalent inorganic cation homeostasisGO:00725031620.027
divalent inorganic cation transportGO:00725111340.027
muscle contractionGO:0006936880.027
negative regulation of chronic inflammatory responseGO:000267720.027
positive regulation of molecular functionGO:00440932300.027
secretion by cellGO:00329402480.027
regulation of excretionGO:0044062210.027
oxidation reduction processGO:00551143040.027
response to organophosphorusGO:00466831020.027
striated muscle tissue developmentGO:0014706580.027
renal sodium excretionGO:0035812200.027
cellular component assemblyGO:00226073600.027
negative regulation of apoptotic processGO:00430661810.027
response to woundingGO:00096112540.027
positive regulation of blood circulationGO:1903524650.026
release of sequestered calcium ion into cytosolGO:0051209250.026
organic acid metabolic processGO:00060822920.026
negative regulation of secretionGO:0051048820.026
single organism reproductive processGO:00447022970.026
positive regulation of gene expressionGO:00106282440.026
regulation of peptide transportGO:0090087870.026
negative regulation of macromolecule metabolic processGO:00106052600.026
positive regulation of cellular component organizationGO:00511302000.026
synapse assemblyGO:0007416290.025
positive regulation of cell communicationGO:00106472710.025
amide transportGO:00428861050.025
cellular response to peptideGO:19016531330.025
erk1 and erk2 cascadeGO:0070371480.025
amine metabolic processGO:0009308380.025
inorganic cation transmembrane transportGO:00986622020.025
muscle cell proliferationGO:0033002840.025
cellular lipid metabolic processGO:00442552080.025
regulation of cell migrationGO:00303341280.025
response to hexoseGO:00097461440.025
innate immune responseGO:0045087350.024
circadian rhythmGO:0007623880.024
response to blue lightGO:000963710.024
amine transportGO:0015837570.024
inorganic anion transportGO:0015698410.024
multicellular organismal reproductive processGO:00486092330.024
positive regulation of rna metabolic processGO:00512542030.024
regulation of calcium ion transportGO:0051924770.024
regulation of synaptic plasticityGO:0048167700.024
multi organism reproductive processGO:00447032620.023
regulation of cellular ketone metabolic processGO:0010565270.023
cytosolic calcium ion transportGO:0060401390.023
regulation of anatomical structure sizeGO:00900661350.023
negative regulation of homeostatic processGO:0032845470.023
cellular response to molecule of bacterial originGO:0071219560.023
response to cytokineGO:00340972150.023
peptide hormone secretionGO:0030072840.023
organic hydroxy compound metabolic processGO:19016151150.023
regulation of systemic arterial blood pressureGO:0003073300.023
second messenger mediated signalingGO:0019932510.023
establishment of protein localizationGO:00451841410.022
regulation of sodium ion transmembrane transporter activityGO:200064940.022
response to external biotic stimulusGO:00432072210.022
response to transition metal nanoparticleGO:19902671220.022
regulation of phosphorus metabolic processGO:00511743490.022
regulation of amino acid transportGO:0051955250.022
cellular response to lipidGO:00713962010.021
carboxylic acid metabolic processGO:00197522890.021
female mating behaviorGO:006018060.021
regulation of cellular component movementGO:00512701500.021
potassium ion transmembrane transportGO:0071805710.021
neurological system processGO:00508772190.021
regulation of intracellular signal transductionGO:19025312180.021
negative regulation of cellular metabolic processGO:00313242810.021
regulation of signal transductionGO:00099663180.021
response to mineralocorticoidGO:0051385490.021
tissue developmentGO:00098882520.021
programmed cell deathGO:00125013920.020
positive regulation of homeostatic processGO:0032846490.020
negative regulation of cell differentiationGO:0045596990.020
wound healingGO:00420601220.020
response to radiationGO:00093141370.020
regulation of organ morphogenesisGO:2000027220.020
regulation of metal ion transportGO:00109591180.020
regulation of action potentialGO:0098900140.020
cellular response to acid chemicalGO:0071229750.020
regulation of hormone levelsGO:00108171870.020
positive regulation of action potentialGO:004576080.020
mapk cascadeGO:00001651400.020
response to temperature stimulusGO:0009266940.019
regulation of body fluid levelsGO:0050878900.019
regulation of peptide hormone secretionGO:0090276800.019
purine ribonucleotide metabolic processGO:00091502270.019
response to vitaminGO:00332731310.019
cellular response to abiotic stimulusGO:0071214850.019
eosinophil chemotaxisGO:004824530.019
regulation of protein phosphorylationGO:00019321830.019
divalent metal ion transportGO:00708381320.019
tube developmentGO:0035295890.019
regulation of neuron differentiationGO:00456642080.019
endocrine system developmentGO:0035270300.019
carbohydrate derivative biosynthetic processGO:19011371240.018
response to histamineGO:003477630.018
cytoplasmic transportGO:00164821150.018
response to antibioticGO:0046677390.018
vesicle mediated transportGO:00161921810.018
response to testosteroneGO:0033574550.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
chemosensory behaviorGO:000763520.018
positive regulation of catalytic activityGO:00430851840.018
response to cocaineGO:0042220390.018
organ formationGO:004864530.017
ossificationGO:0001503700.017
potassium ion transportGO:0006813970.017
excretionGO:0007588240.017
blood vessel morphogenesisGO:0048514580.017
l glutamate importGO:005193820.017
positive regulation of amino acid transportGO:0051957130.017
cell morphogenesis involved in differentiationGO:00009041190.017
peptide transportGO:0015833970.017
eye morphogenesisGO:004859240.017
carboxylic acid transportGO:00469421150.017
defecationGO:003042110.017
nitrogen compound transportGO:00717052290.017
response to activityGO:0014823730.017
oxoacid metabolic processGO:00434362900.017
cellular response to steroid hormone stimulusGO:0071383930.017
regulation of cellular component biogenesisGO:0044087860.017
organic hydroxy compound transportGO:0015850770.017
insulin secretionGO:0030073690.016
actin filament based processGO:0030029860.016
response to fatty acidGO:0070542650.016
gliogenesisGO:0042063930.016
defense response to gram positive bacteriumGO:005083020.016
cellular response to peptide hormone stimulusGO:00713751200.016
regulation of neurological system processGO:0031644430.016
organic anion transportGO:00157111320.016
reactive oxygen species metabolic processGO:0072593370.016
hormone secretionGO:00468791150.016
muscle tissue developmentGO:0060537580.016
liver developmentGO:0001889900.016
muscle structure developmentGO:0061061870.016
positive regulation of organic acid transportGO:0032892220.016
regulation of neurotransmitter levelsGO:0001505420.016
developmental process involved in reproductionGO:00030061590.016
regulation of release of sequestered calcium ion into cytosolGO:0051279180.016
response to monosaccharideGO:00342841590.016
regulation of peptide secretionGO:0002791820.016
regulation of cellular amino acid metabolic processGO:000652120.016
catecholamine secretionGO:0050432330.016
nucleoside phosphate biosynthetic processGO:19012931020.016
regulation of tube sizeGO:0035150890.016
transmission of nerve impulseGO:0019226420.015
response to osmotic stressGO:0006970420.015
response to corticosteroidGO:00319602350.015
regulation of hormone secretionGO:00468831060.015
response to increased oxygen levelsGO:0036296450.015
memoryGO:0007613540.015
negative regulation of secretion by cellGO:1903531720.015
positive regulation of cytoplasmic transportGO:1903651320.015
tissue regenerationGO:0042246360.015
positive regulation of fat cell proliferationGO:007034610.015
regulation of cellular amine metabolic processGO:003323880.015
synapse organizationGO:0050808460.015
smooth muscle contractionGO:0006939370.015
calcium ion transportGO:00068161310.015
renal system processGO:0003014400.015
regulation of epithelial cell proliferationGO:0050678490.014
cellular response to ammonium ionGO:0071242170.014
response to gonadotropinGO:0034698340.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.014
defense responseGO:00069521940.014
positive regulation of neuron projection developmentGO:0010976990.014
positive regulation of hormone secretionGO:0046887650.014
regulation of apoptotic processGO:00429813350.014
cellular response to ketoneGO:1901655510.014
hormone transportGO:00099141210.014
regulation of protein metabolic processGO:00512462890.014
sodium ion homeostasisGO:0055078230.014
single organism intracellular transportGO:19025821660.014
nucleotide metabolic processGO:00091172790.014
apoptotic processGO:00069153810.014
mast cell migrationGO:009753140.014
regulation of sensory perception of painGO:0051930290.014
epithelial cell proliferationGO:0050673540.014
spermatogenesisGO:0007283990.014
negative regulation of neuron deathGO:1901215690.014
regulation of calcium ion transport into cytosolGO:0010522250.014
axon developmentGO:0061564960.013
regulation of muscle system processGO:0090257790.013
regulation of sequestering of calcium ionGO:0051282260.013
positive regulation of hydrolase activityGO:0051345860.013
protein targetingGO:0006605610.013
pyruvate metabolic processGO:0006090270.013
reactive oxygen species biosynthetic processGO:190340980.013
response to anoxiaGO:003405940.013
single organism organelle organizationGO:19025891800.013
heart developmentGO:0007507720.013
regulation of feeding behaviorGO:0060259140.013
neuron neuron synaptic transmissionGO:0007270600.013
axonogenesisGO:0007409710.013
intracellular protein transportGO:0006886790.013
fat cell proliferationGO:007034120.013
response to hypoxiaGO:00016662310.013
regulation of intracellular transportGO:0032386650.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
neurotransmitter uptakeGO:000150430.013
protein phosphorylationGO:00064683450.013
positive regulation of phosphorus metabolic processGO:00105622620.013
intracellular receptor signaling pathwayGO:0030522350.013
positive regulation of peptide secretionGO:0002793520.013
cellular response to organic cyclic compoundGO:00714072020.013
acid secretionGO:0046717480.013
microglial cell activationGO:0001774140.013
axis specificationGO:000979840.012
single organism biosynthetic processGO:00447113420.012
regulation of actin cytoskeleton organizationGO:0032956300.012
hematopoietic or lymphoid organ developmentGO:0048534360.012
regulation of organelle organizationGO:0033043800.012
regulation of insulin secretionGO:0050796650.012
response to other organismGO:00517072200.012
response to purine containing compoundGO:00140741260.012
circadian regulation of gene expressionGO:003292230.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
sexual reproductionGO:00199531480.012
regulation of growthGO:00400081050.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
response to nicotineGO:0035094510.012
response to glucoseGO:00097491360.012
cardiac muscle tissue developmentGO:0048738260.012
sensory organ developmentGO:0007423740.012
regulation of vasoconstrictionGO:0019229440.012
defense response to gram negative bacteriumGO:005082930.012
regulation of cellular protein metabolic processGO:00322682670.012
nerve developmentGO:0021675110.012
regulation of vascular permeabilityGO:0043114100.012
positive regulation of neurogenesisGO:00507691650.012
male gamete generationGO:0048232990.012
positive regulation of smooth muscle cell proliferationGO:0048661510.012
urinary bladder smooth muscle contractionGO:001483240.012
small gtpase mediated signal transductionGO:0007264360.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
negative regulation of synaptic transmission dopaminergicGO:003222740.012
organ regenerationGO:00311001010.012
response to hyperoxiaGO:0055093450.012
striated muscle contractionGO:0006941440.012
dicarboxylic acid transportGO:0006835340.012
gamete generationGO:00072761240.011
negative regulation of response to external stimulusGO:0032102370.011
positive regulation of neuron differentiationGO:00456661260.011
negative regulation of long term synaptic potentiationGO:190027210.011
anatomical structure morphogenesisGO:00096532980.011
regulation of neuronal synaptic plasticityGO:0048168310.011
proteolysisGO:00065081750.011
muscle cell differentiationGO:0042692520.011
nucleobase containing small molecule metabolic processGO:00550863160.011
regulation of smooth muscle cell proliferationGO:0048660750.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
cardiac chamber developmentGO:000320510.011
response to interferon gammaGO:0034341200.011
fatty acid metabolic processGO:0006631990.011
multicellular organismal signalingGO:0035637440.011
cell type specific apoptotic processGO:00972851340.011
organ inductionGO:000175910.011
dephosphorylationGO:0016311980.011
organelle organizationGO:00069962660.011
cellular response to mechanical stimulusGO:0071260480.011
cellular response to biotic stimulusGO:0071216590.011
positive regulation of purine nucleotide biosynthetic processGO:1900373360.011
alcohol metabolic processGO:0006066770.011
positive regulation of phosphorylationGO:00423271770.011
cellular macromolecular complex assemblyGO:0034622580.011
cellular response to cytokine stimulusGO:00713451270.011
protein tetramerizationGO:0051262380.011
regulation of transcription regulatory region dna bindingGO:200067740.010
ribose phosphate metabolic processGO:00196932350.010
negative regulation of sequestering of calcium ionGO:0051283250.010
regulation of organic acid transportGO:0032890350.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
positive regulation of cell projection organizationGO:00313461110.010

Kcna2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.014
urinary system diseaseDOID:1800.014
nervous system diseaseDOID:86300.013
disease of metabolismDOID:001466700.012
musculoskeletal system diseaseDOID:1700.011