Rattus norvegicus

0 known processes

Topbp1

topoisomerase (DNA) II binding protein 1

(Aliases: RGD1562949)

Topbp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.064
organic acid metabolic processGO:00060822920.052
cellular response to endogenous stimulusGO:00714953770.052
cellular amino acid metabolic processGO:00065201070.046
carbohydrate derivative metabolic processGO:19011353460.038
response to nutrient levelsGO:00316673700.036
oxoacid metabolic processGO:00434362900.035
regulation of nucleic acid templated transcriptionGO:19035063800.033
transcription dna templatedGO:00063513770.032
negative regulation of gene expressionGO:00106291990.031
transcription from rna polymerase ii promoterGO:00063662520.030
regulation of programmed cell deathGO:00430673410.030
regulation of rna metabolic processGO:00512523910.028
regulation of molecular functionGO:00650093980.028
negative regulation of metabolic processGO:00098923310.027
apoptotic processGO:00069153810.027
positive regulation of nitrogen compound metabolic processGO:00511733340.026
regulation of cellular ketone metabolic processGO:0010565270.026
negative regulation of macromolecule metabolic processGO:00106052600.026
organophosphate metabolic processGO:00196373700.026
cellular amine metabolic processGO:0044106380.026
head developmentGO:00603222470.025
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.025
nucleoside phosphate metabolic processGO:00067532830.025
cellular modified amino acid metabolic processGO:0006575610.025
regulation of cellular amine metabolic processGO:003323880.025
protein phosphorylationGO:00064683450.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
brain developmentGO:00074202470.024
cellular ketone metabolic processGO:0042180510.024
regulation of cellular amino acid metabolic processGO:000652120.024
regulation of rna biosynthetic processGO:20011413810.024
programmed cell deathGO:00125013920.023
response to extracellular stimulusGO:00099913800.023
negative regulation of cellular biosynthetic processGO:00313271610.023
regulation of cell differentiationGO:00455953200.023
rna biosynthetic processGO:00327743800.022
neuron differentiationGO:00301823680.022
regulation of protein metabolic processGO:00512462890.022
cellular response to growth factor stimulusGO:00713631620.021
single organism biosynthetic processGO:00447113420.021
nucleic acid templated transcriptionGO:00976593790.021
cellular response to stressGO:00335542690.021
nucleotide metabolic processGO:00091172790.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
central nervous system developmentGO:00074173110.021
cellular response to oxygen containing compoundGO:19017013860.021
purine containing compound metabolic processGO:00725212530.021
positive regulation of transportGO:00510502450.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
nucleobase containing small molecule metabolic processGO:00550863160.020
regulation of cell developmentGO:00602842630.020
negative regulation of biosynthetic processGO:00098901680.020
positive regulation of cell deathGO:00109421840.020
organic substance catabolic processGO:19015753160.020
negative regulation of cellular metabolic processGO:00313242810.020
ribose phosphate metabolic processGO:00196932350.019
positive regulation of biosynthetic processGO:00098913190.019
response to nutrientGO:00075842480.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
single organism reproductive processGO:00447022970.019
response to estradiolGO:00323551640.019
macromolecular complex subunit organizationGO:00439333390.019
protein oligomerizationGO:00512591910.018
homeostatic processGO:00425923310.018
catabolic processGO:00090563510.018
cellular response to lipidGO:00713962010.018
purine nucleoside metabolic processGO:00422781690.018
amine metabolic processGO:0009308380.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
cellular response to nitrogen compoundGO:19016992100.017
regulation of neurogenesisGO:00507672470.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
positive regulation of cell differentiationGO:00455972170.017
positive regulation of neurogenesisGO:00507691650.017
regulation of transcription dna templatedGO:00063553740.017
regulation of cellular component organizationGO:00511283680.017
regulation of catalytic activityGO:00507903040.017
response to inorganic substanceGO:00100353770.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
cellular response to organonitrogen compoundGO:00714171970.016
regenerationGO:00310991630.016
positive regulation of cellular biosynthetic processGO:00313282950.016
regulation of cellular protein metabolic processGO:00322682670.016
response to ethanolGO:00454711620.015
response to estrogenGO:00436272320.015
regulation of cellular localizationGO:00603412630.015
positive regulation of cell developmentGO:00107201760.015
negative regulation of transcription dna templatedGO:00458921160.015
organonitrogen compound biosynthetic processGO:19015661670.015
cellular response to hormone stimulusGO:00328702470.015
positive regulation of multicellular organismal processGO:00512403870.015
positive regulation of rna biosynthetic processGO:19026801970.015
negative regulation of programmed cell deathGO:00430691830.015
positive regulation of molecular functionGO:00440932300.015
negative regulation of rna biosynthetic processGO:19026791180.015
positive regulation of transcription dna templatedGO:00458931970.015
regulation of cell projection organizationGO:00313441750.015
response to growth factorGO:00708481890.015
macromolecular complex assemblyGO:00650032730.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.015
ras protein signal transductionGO:0007265290.015
positive regulation of nervous system developmentGO:00519621780.015
regulation of cell proliferationGO:00421273590.014
regulation of apoptotic processGO:00429813350.014
positive regulation of apoptotic processGO:00430651540.014
regulation of phosphate metabolic processGO:00192203490.014
agingGO:00075682410.014
neuron deathGO:00709971270.014
lipid metabolic processGO:00066292830.014
cell cell signalingGO:00072673350.014
transmembrane transportGO:00550854120.014
nucleoside metabolic processGO:00091161790.014
neuron projection developmentGO:00311752730.014
response to woundingGO:00096112540.014
cell projection organizationGO:00300303020.014
chemical homeostasisGO:00488782920.014
forebrain developmentGO:0030900980.014
single organism catabolic processGO:00447122830.014
ribonucleoside metabolic processGO:00091191740.014
signal releaseGO:00230611450.013
cellular response to organic cyclic compoundGO:00714072020.013
glycosyl compound metabolic processGO:19016571820.013
cellular chemical homeostasisGO:00550822470.013
response to ketoneGO:19016541820.013
ribonucleotide metabolic processGO:00092592310.013
cation transportGO:00068123820.013
reproductionGO:00000032450.013
negative regulation of multicellular organismal processGO:00512412030.013
cellular component biogenesisGO:00440853680.013
regulation of neuron differentiationGO:00456642080.013
positive regulation of neuron projection developmentGO:0010976990.013
regulation of nervous system developmentGO:00519602640.013
neuron developmentGO:00486662860.013
positive regulation of cell proliferationGO:00082842490.013
regulation of signal transductionGO:00099663180.013
negative regulation of protein metabolic processGO:00512481140.013
ion transmembrane transportGO:00342203650.013
dna metabolic processGO:0006259960.013
negative regulation of cell deathGO:00605482290.012
axis specificationGO:000979840.012
regulation of phosphorus metabolic processGO:00511743490.012
purine nucleotide metabolic processGO:00061632290.012
anterior posterior pattern specificationGO:000995210.012
cofactor metabolic processGO:0051186950.012
macromolecule localizationGO:00330362520.012
response to vitaminGO:00332731310.012
positive regulation of gene expressionGO:00106282440.012
regulation of multicellular organismal developmentGO:20000263760.012
chromosome segregationGO:000705920.012
regulation of secretion by cellGO:19035302080.012
regulation of establishment of protein localizationGO:0070201690.012
cellular component assemblyGO:00226073600.012
organophosphate biosynthetic processGO:00904071430.012
eye morphogenesisGO:004859240.012
rna metabolic processGO:00160704060.012
multi organism reproductive processGO:00447032620.012
organonitrogen compound catabolic processGO:19015651790.012
nucleoside triphosphate metabolic processGO:00091411440.012
positive regulation of rna metabolic processGO:00512542030.012
purine ribonucleotide metabolic processGO:00091502270.012
intracellular transportGO:00469071850.012
positive regulation of programmed cell deathGO:00430681570.012
negative regulation of rna metabolic processGO:00512531230.012
positive regulation of cell projection organizationGO:00313461110.012
small gtpase mediated signal transductionGO:0007264360.012
negative regulation of innate immune responseGO:004582440.012
cation transmembrane transportGO:00986552630.012
cellular nitrogen compound catabolic processGO:00442701630.012
positive regulation of cellular amine metabolic processGO:003324030.012
inorganic ion transmembrane transportGO:00986602290.011
response to acid chemicalGO:00011012220.011
regulation of protein modification processGO:00313991940.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
negative regulation of catalytic activityGO:00430861030.011
cellular homeostasisGO:00197252520.011
response to peptideGO:19016522920.011
secretionGO:00469033070.011
coenzyme metabolic processGO:0006732860.011
reproductive processGO:00224143720.011
positive regulation of developmental processGO:00510942830.011
response to radiationGO:00093141370.011
positive regulation of neuron differentiationGO:00456661260.011
regulation of response to stressGO:00801341260.011
intracellular signal transductionGO:00355563140.011
negative regulation of apoptotic processGO:00430661810.011
oxidation reduction processGO:00551143040.011
protein complex subunit organizationGO:00718223020.011
response to alkaloidGO:00432791320.011
motor neuron axon guidanceGO:000804510.011
carbohydrate derivative biosynthetic processGO:19011371240.011
cell adhesionGO:00071551100.011
nucleobase containing compound catabolic processGO:00346551520.011
purine ribonucleoside metabolic processGO:00461281680.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
liver developmentGO:0001889900.011
negative regulation of molecular functionGO:00440921330.011
localization of cellGO:00516742020.011
positive regulation of catalytic activityGO:00430851840.011
cell type specific apoptotic processGO:00972851340.011
alpha amino acid metabolic processGO:1901605710.011
response to metal ionGO:00100382530.011
negative regulation of cellular protein metabolic processGO:00322691060.011
positive regulation of protein modification processGO:00314011420.011
organic cyclic compound catabolic processGO:19013611750.010
rho protein signal transductionGO:0007266110.010
multicellular organism growthGO:003526410.010
cellular protein localizationGO:00346131220.010
regulation of hormone levelsGO:00108171870.010
cellular response to alcoholGO:0097306870.010
response to purine containing compoundGO:00140741260.010
positive regulation of protein metabolic processGO:00512471780.010
response to external biotic stimulusGO:00432072210.010
positive regulation of response to stimulusGO:00485842850.010
secretion by cellGO:00329402480.010
single organism intracellular transportGO:19025821660.010
multicellular organismal reproductive processGO:00486092330.010
multicellular organism reproductionGO:00325042330.010
regulation of protein phosphorylationGO:00019321830.010
positive regulation of cell communicationGO:00106472710.010

Topbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
central nervous system diseaseDOID:33100.012