Rattus norvegicus

0 known processes

Itih4

inter alpha-trypsin inhibitor, heavy chain 4

Itih4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrientGO:00075842480.336
regenerationGO:00310991630.324
negative regulation of gene expressionGO:00106291990.303
response to acid chemicalGO:00011012220.283
response to extracellular stimulusGO:00099913800.245
response to metal ionGO:00100382530.219
regulation of rna biosynthetic processGO:20011413810.210
rna biosynthetic processGO:00327743800.202
response to inorganic substanceGO:00100353770.186
blood coagulationGO:0007596260.183
organ regenerationGO:00311001010.183
positive regulation of multicellular organismal processGO:00512403870.177
response to other organismGO:00517072200.177
response to platinum ionGO:007054140.174
transcription dna templatedGO:00063513770.170
gland developmentGO:00487321550.165
regulation of apoptotic processGO:00429813350.165
apoptotic processGO:00069153810.164
response to external biotic stimulusGO:00432072210.161
negative regulation of macromolecule metabolic processGO:00106052600.156
transcription from rna polymerase ii promoterGO:00063662520.152
programmed cell deathGO:00125013920.151
immune responseGO:00069551040.149
regulation of transcription dna templatedGO:00063553740.147
regulation of programmed cell deathGO:00430673410.145
macromolecular complex assemblyGO:00650032730.136
negative regulation of response to stimulusGO:00485851550.136
coagulationGO:0050817280.129
regulation of body fluid levelsGO:0050878900.127
negative regulation of metabolic processGO:00098923310.125
positive regulation of response to stimulusGO:00485842850.119
single organism reproductive processGO:00447022970.114
cellular response to oxygen containing compoundGO:19017013860.111
liver developmentGO:0001889900.106
response to estrogenGO:00436272320.103
regulation of nucleic acid templated transcriptionGO:19035063800.101
urea metabolic processGO:001962750.101
response to peptideGO:19016522920.101
cellular response to endogenous stimulusGO:00714953770.100
cellular component assemblyGO:00226073600.098
protein maturationGO:0051604680.097
cellular component biogenesisGO:00440853680.093
regulation of protein metabolic processGO:00512462890.092
negative regulation of protein metabolic processGO:00512481140.091
response to glucocorticoidGO:00513842230.089
positive regulation of rna biosynthetic processGO:19026801970.089
response to nutrient levelsGO:00316673700.086
positive regulation of gene expressionGO:00106282440.086
proteolysisGO:00065081750.086
immune system processGO:00023762040.086
cellular response to steroid hormone stimulusGO:0071383930.085
response to transition metal nanoparticleGO:19902671220.085
cellular response to stressGO:00335542690.085
regulation of phosphorylationGO:00423252480.083
protein complex subunit organizationGO:00718223020.083
response to estradiolGO:00323551640.081
response to lipopolysaccharideGO:00324961910.080
cellular response to organonitrogen compoundGO:00714171970.078
positive regulation of biosynthetic processGO:00098913190.078
reproductive processGO:00224143720.078
regulation of signal transductionGO:00099663180.077
defense responseGO:00069521940.077
Human
response to monosaccharideGO:00342841590.076
response to oxygen levelsGO:00704822650.076
cellular response to lipidGO:00713962010.076
circulatory system developmentGO:00723591340.075
rhythmic processGO:00485111560.074
regulation of protein processingGO:0070613500.074
urea cycleGO:000005050.073
positive regulation of hormone secretionGO:0046887650.072
central nervous system developmentGO:00074173110.071
hemostasisGO:0007599260.070
immunoglobulin mediated immune responseGO:001606440.069
response to decreased oxygen levelsGO:00362932370.069
secretion by cellGO:00329402480.068
rna metabolic processGO:00160704060.067
negative regulation of cellular metabolic processGO:00313242810.067
negative regulation of proteolysisGO:0045861410.067
nitrogen compound transportGO:00717052290.066
macromolecular complex subunit organizationGO:00439333390.065
response to molecule of bacterial originGO:00022371940.065
positive regulation of cell differentiationGO:00455972170.064
response to carbohydrateGO:00097431830.064
regulation of secretionGO:00510462240.063
response to peptide hormoneGO:00434342780.063
cellular amide metabolic processGO:0043603440.061
amine metabolic processGO:0009308380.061
regulation of protein maturationGO:1903317500.061
circadian rhythmGO:0007623880.061
regulation of multicellular organismal developmentGO:20000263760.061
negative regulation of molecular functionGO:00440921330.060
negative regulation of peptidase activityGO:0010466380.059
regulation of behaviorGO:0050795610.059
cation transportGO:00068123820.058
neuron projection developmentGO:00311752730.058
regulation of cellular protein metabolic processGO:00322682670.058
negative regulation of protein maturationGO:1903318470.056
positive regulation of nitrogen compound metabolic processGO:00511733340.055
regulation of cell proliferationGO:00421273590.055
protein processingGO:0016485680.054
positive regulation of macromolecule biosynthetic processGO:00105572470.054
b cell mediated immunityGO:001972440.053
response to biotic stimulusGO:00096072260.053
reproductionGO:00000032450.053
positive regulation of signalingGO:00230562700.052
regulation of immunoglobulin mediated immune responseGO:000288920.052
fibrinolysisGO:004273020.052
intracellular signal transductionGO:00355563140.051
hepaticobiliary system developmentGO:0061008900.051
cellular response to nitrogen compoundGO:19016992100.050
inflammatory responseGO:00069541500.050
Human
protein complex biogenesisGO:00702712630.049
protein phosphorylationGO:00064683450.049
regulation of circadian sleep wake cycleGO:0042749180.049
response to campGO:0051591910.049
immune effector processGO:0002252530.049
positive regulation of cellular biosynthetic processGO:00313282950.047
response to retinoic acidGO:0032526630.047
cellular response to peptide hormone stimulusGO:00713751200.047
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.047
response to bacteriumGO:00096172000.046
neuron differentiationGO:00301823680.046
organic substance catabolic processGO:19015753160.046
negative regulation of multicellular organismal processGO:00512412030.046
positive regulation of nucleic acid templated transcriptionGO:19035081970.046
secretionGO:00469033070.046
mapk cascadeGO:00001651400.045
protein oligomerizationGO:00512591910.045
response to hexoseGO:00097461440.045
macromolecule localizationGO:00330362520.044
multi multicellular organism processGO:00447061380.043
negative regulation of response to woundingGO:1903035230.043
positive regulation of apoptotic processGO:00430651540.043
protein complex assemblyGO:00064612630.042
response to corticosteroidGO:00319602350.042
regulation of mapk cascadeGO:00434081160.042
cellular amino acid metabolic processGO:00065201070.041
regulation of hydrolase activityGO:00513361430.041
regulation of neurogenesisGO:00507672470.041
regulation of molecular functionGO:00650093980.040
behaviorGO:00076102050.040
negative regulation of developmental processGO:00510931250.040
response to hypoxiaGO:00016662310.040
gliogenesisGO:0042063930.039
regulation of anatomical structure morphogenesisGO:00226031410.039
negative regulation of cellular protein metabolic processGO:00322691060.039
hepatocyte differentiationGO:007036580.039
regulation of serine type peptidase activityGO:190257110.038
positive regulation of mapk cascadeGO:0043410920.038
cellular response to hormone stimulusGO:00328702470.038
regulation of rna metabolic processGO:00512523910.037
positive regulation of programmed cell deathGO:00430681570.037
anion transportGO:00068201780.036
regulation of b cell mediated immunityGO:000271220.036
negative regulation of protein processingGO:0010955470.036
single organism biosynthetic processGO:00447113420.036
positive regulation of intracellular signal transductionGO:19025331380.036
positive regulation of developmental processGO:00510942830.035
negative regulation of endopeptidase activityGO:0010951360.035
regulation of cellular localizationGO:00603412630.035
regulation of hemostasisGO:190004690.034
regulation of locomotionGO:00400121480.034
regulation of transcription from rna polymerase ii promoterGO:00063572340.034
organic acid metabolic processGO:00060822920.034
positive regulation of cellular component organizationGO:00511302000.034
plasminogen activationGO:003163920.033
nucleic acid templated transcriptionGO:00976593790.033
developmental process involved in reproductionGO:00030061590.033
response to woundingGO:00096112540.033
response to vitamin b6GO:003451610.032
regulation of phosphorus metabolic processGO:00511743490.032
negative regulation of cell deathGO:00605482290.031
positive regulation of nervous system developmentGO:00519621780.031
positive regulation of blood coagulationGO:003019440.031
positive regulation of phosphate metabolic processGO:00459372620.031
regulation of cell developmentGO:00602842630.031
multi organism reproductive processGO:00447032620.031
regulation of cell differentiationGO:00455953200.031
regulation of peptidase activityGO:0052547550.031
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
response to vitaminGO:00332731310.030
regulation of immune system processGO:00026821230.030
regulation of nervous system developmentGO:00519602640.030
response to purine containing compoundGO:00140741260.030
hindbrain morphogenesisGO:002157520.030
negative regulation of programmed cell deathGO:00430691830.030
oxoacid metabolic processGO:00434362900.030
nitrogen cycle metabolic processGO:007194150.029
regulation of cellular ketone metabolic processGO:0010565270.029
carboxylic acid biosynthetic processGO:0046394830.029
regulation of endopeptidase activityGO:0052548510.029
protein homooligomerizationGO:0051260910.029
drug transportGO:0015893180.029
multicellular organismal signalingGO:0035637440.028
cardiovascular system developmentGO:00723581340.028
positive regulation of signal transductionGO:00099671750.028
negative regulation of cell communicationGO:00106481580.028
negative regulation of signal transductionGO:0009968830.028
cellular ketone metabolic processGO:0042180510.028
cellular response to growth factor stimulusGO:00713631620.028
localization of cellGO:00516742020.028
lipid biosynthetic processGO:00086101280.028
regulation of cellular amine metabolic processGO:003323880.027
regulation of proteolysisGO:0030162660.027
response to organophosphorusGO:00466831020.027
regulation of heterotypic cell cell adhesionGO:003411420.027
organic hydroxy compound transportGO:0015850770.027
cellular amine metabolic processGO:0044106380.027
negative regulation of cellular amide metabolic processGO:003424910.027
regulation of response to stressGO:00801341260.027
regulation of endothelial cell proliferationGO:0001936180.027
small molecule biosynthetic processGO:00442831240.026
regulation of secretion by cellGO:19035302080.026
regulation of cellular amino acid metabolic processGO:000652120.026
brain developmentGO:00074202470.026
multicellular organism reproductionGO:00325042330.026
cell projection organizationGO:00300303020.026
head developmentGO:00603222470.025
positive regulation of transportGO:00510502450.025
anatomical structure morphogenesisGO:00096532980.025
regulation of cellular component organizationGO:00511283680.025
response to mercury ionGO:0046689150.025
positive regulation of molecular functionGO:00440932300.025
female pregnancyGO:00075651220.025
cellular response to organic cyclic compoundGO:00714072020.025
regulation of amine transportGO:0051952540.024
positive regulation of immunoglobulin mediated immune responseGO:000289120.024
developmental growthGO:00485891000.024
response to ethanolGO:00454711620.023
regulation of intracellular signal transductionGO:19025312180.023
response to cytokineGO:00340972150.023
Human
regulation of cell growthGO:0001558850.022
regulation of immune responseGO:0050776550.022
homeostatic processGO:00425923310.022
epithelium developmentGO:0060429960.022
cellular sodium ion homeostasisGO:000688340.022
growthGO:00400071650.022
extracellular matrix constituent secretionGO:007027840.022
negative regulation of signalingGO:00230571570.021
development of primary sexual characteristicsGO:00451371070.021
regulation of phosphate metabolic processGO:00192203490.021
negative regulation of catalytic activityGO:00430861030.021
carboxylic acid transportGO:00469421150.021
response to calcium ionGO:0051592590.021
blood vessel morphogenesisGO:0048514580.021
positive regulation of hepatocyte differentiationGO:007036820.021
ion homeostasisGO:00508012120.021
anterior posterior pattern specificationGO:000995210.021
response to glucoseGO:00097491360.021
glycogen metabolic processGO:0005977230.021
positive regulation of cell deathGO:00109421840.021
organic anion transportGO:00157111320.020
mammary gland developmentGO:0030879380.020
positive regulation of b cell mediated immunityGO:000271420.020
organic acid biosynthetic processGO:0016053830.020
agingGO:00075682410.020
hepatocyte proliferationGO:007257430.020
cellular response to molecule of bacterial originGO:0071219560.020
protein localizationGO:00081041910.020
carbohydrate homeostasisGO:0033500750.020
glial cell differentiationGO:0010001650.020
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.020
regulation of plasminogen activationGO:001075520.019
reproductive system developmentGO:00614581280.019
taxisGO:0042330670.019
multicellular organismal reproductive processGO:00486092330.019
locomotionGO:00400112370.019
positive regulation of rna metabolic processGO:00512542030.019
positive regulation of cellular amine metabolic processGO:003324030.019
positive regulation of circadian rhythmGO:0042753110.019
norepinephrine secretionGO:0048243160.019
regulation of neuron differentiationGO:00456642080.019
peptide metabolic processGO:0006518320.019
positive regulation of immune system processGO:0002684900.019
negative regulation of apoptotic processGO:00430661810.018
cellular response to lipopolysaccharideGO:0071222550.018
catabolic processGO:00090563510.018
positive regulation of cell communicationGO:00106472710.018
response to interleukin 1GO:0070555550.018
positive regulation of catalytic activityGO:00430851840.018
amine transportGO:0015837570.018
regulation of cell projection organizationGO:00313441750.018
negative regulation of serine type endopeptidase activityGO:190000410.018
transmembrane transportGO:00550854120.018
negative regulation of rna metabolic processGO:00512531230.018
positive regulation of extracellular matrix organizationGO:190305540.018
cholesterol homeostasisGO:004263230.018
positive regulation of peptide secretionGO:0002793520.018
regulation of response to external stimulusGO:00321011060.018
catecholamine secretionGO:0050432330.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
response to lead ionGO:0010288330.017
regulation of homeostatic processGO:00328441010.017
cellular response to corticosteroid stimulusGO:0071384690.017
defense response to gram negative bacteriumGO:005082930.017
gonad developmentGO:00084061040.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
positive regulation of phosphorylationGO:00423271770.017
positive regulation of protein metabolic processGO:00512471780.017
cofactor metabolic processGO:0051186950.017
positive regulation of neurogenesisGO:00507691650.017
carboxylic acid metabolic processGO:00197522890.016
positive regulation of behaviorGO:0048520380.016
organic acid transportGO:00158491160.016
neuron developmentGO:00486662860.016
regulation of endothelial cell apoptotic processGO:200035130.016
positive regulation of immune responseGO:0050778420.016
response to triglycerideGO:003401430.016
regulation of serine type endopeptidase activityGO:190000310.016
cell matrix adhesionGO:0007160190.016
response to growth factorGO:00708481890.016
positive regulation of secretionGO:00510471400.016
anatomical structure formation involved in morphogenesisGO:0048646830.016
single organism intracellular transportGO:19025821660.016
regulation of response to woundingGO:1903034690.016
coenzyme metabolic processGO:0006732860.016
signal transduction by phosphorylationGO:00230141440.016
response to alkaloidGO:00432791320.015
response to amino acidGO:0043200750.015
negative regulation of biomineral tissue developmentGO:007016820.015
organ morphogenesisGO:0009887750.015
neuron deathGO:00709971270.015
cell activationGO:0001775970.015
positive regulation of cell developmentGO:00107201760.015
defecationGO:003042110.015
body fluid secretionGO:0007589410.015
purine containing compound metabolic processGO:00725212530.015
cellular response to fluid shear stressGO:007149840.015
alcohol metabolic processGO:0006066770.015
antibiotic transportGO:004289120.015
angiogenesisGO:0001525530.015
positive regulation of transcription dna templatedGO:00458931970.015
epinephrine secretionGO:004824260.015
regulation of immunoglobulin productionGO:000263740.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
blood vessel developmentGO:0001568690.015
vesicle mediated transportGO:00161921810.014
response to ketoneGO:19016541820.014
mesoderm developmentGO:000749820.014
cellular response to campGO:0071320260.014
response to chromateGO:004668730.014
sex differentiationGO:00075481130.014
wound healingGO:00420601220.014
negative regulation of serine type peptidase activityGO:190257210.014
ion transmembrane transportGO:00342203650.014
extracellular matrix organizationGO:0030198130.014
smooth muscle cell proliferationGO:0048659770.014
monoamine transportGO:0015844430.014
positive regulation of hemostasisGO:190004840.014
cellular response to glucose stimulusGO:0071333650.014
protein activation cascadeGO:0072376120.014
cellular component movementGO:00069282480.014
epithelial cell differentiationGO:0030855710.014
cellular lipid metabolic processGO:00442552080.014
transmission of nerve impulseGO:0019226420.014
regulation of catecholamine secretionGO:0050433320.014
response to hyperoxiaGO:0055093450.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
positive regulation of cell proliferationGO:00082842490.014
cytolysisGO:001983540.014
leydig cell differentiationGO:003332780.014
regulation of reactive oxygen species biosynthetic processGO:190342650.014
cellular response to insulin stimulusGO:0032869810.013
regulation of protein modification processGO:00313991940.013
renal sodium excretionGO:0035812200.013
response to amineGO:0014075460.013
epithelial cell proliferationGO:0050673540.013
peptidyl amino acid modificationGO:00181931260.013
negative regulation of tissue remodelingGO:003410460.013
regulation of transferase activityGO:00513381230.013
positive regulation of homeostatic processGO:0032846490.013
digestive system developmentGO:0055123410.013
regulation of reactive oxygen species metabolic processGO:2000377260.013
tissue developmentGO:00098882520.013
cellular response to cytokine stimulusGO:00713451270.013
regulation of protein phosphorylationGO:00019321830.013
cellular response to glucocorticoid stimulusGO:0071385680.013
single organism carbohydrate metabolic processGO:00447231180.013
regulation of cell morphogenesisGO:0022604770.013
organophosphate metabolic processGO:00196373700.013
regulation of neuron projection developmentGO:00109751610.013
tube developmentGO:0035295890.013
regulation of cell migrationGO:00303341280.013
negative regulation of calcium ion importGO:009028120.013
negative regulation of cell proliferationGO:00082851190.013
muscle structure developmentGO:0061061870.013
forebrain developmentGO:0030900980.013
cell migrationGO:00164771970.013
spermatogenesisGO:0007283990.013
sterol homeostasisGO:005509230.013
regulation of catalytic activityGO:00507903040.013
circadian sleep wake cycle sleepGO:0050802210.013
negative regulation of hydrolase activityGO:0051346520.013
cellular response to carbohydrate stimulusGO:0071322720.012
cell adhesionGO:00071551100.012
sexual reproductionGO:00199531480.012
vasculature developmentGO:0001944700.012
development of primary female sexual characteristicsGO:0046545560.012
response to zinc ionGO:0010043390.012
cellular response to inorganic substanceGO:0071241650.012
alpha amino acid metabolic processGO:1901605710.012
regulation of circadian sleep wake cycle sleepGO:0045187180.012
muscle cell differentiationGO:0042692520.012
regulation of ion transportGO:00432692450.012
amide transportGO:00428861050.012
macromolecule catabolic processGO:0009057580.012
signal releaseGO:00230611450.012
regulation of protein serine threonine kinase activityGO:0071900640.012
cell cell signalingGO:00072673350.012
heterotypic cell cell adhesionGO:003411320.012
positive regulation of immunoglobulin productionGO:000263940.012
cellular homeostasisGO:00197252520.012
cell type specific apoptotic processGO:00972851340.012
bmp signaling pathwayGO:003050940.012
carbohydrate metabolic processGO:00059751300.012
monocarboxylic acid transportGO:0015718520.012
positive regulation of blood pressureGO:0045777310.012
positive regulation of protein serine threonine kinase activityGO:0071902520.012
cellular response to dexamethasone stimulusGO:0071549360.012
heart morphogenesisGO:000300730.012
nucleobase containing small molecule metabolic processGO:00550863160.011
fatty acid biosynthetic processGO:0006633330.011
limb morphogenesisGO:003510840.011
dendrite morphogenesisGO:0048813430.011
negative regulation of cell developmentGO:0010721820.011
regulation of blood coagulationGO:003019390.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
response to vitamin aGO:0033189360.011
reproductive structure developmentGO:00486081280.011
cellular response to hexose stimulusGO:0071331650.011
cellular response to glucagon stimulusGO:007137770.011
positive regulation of hydrolase activityGO:0051345860.011
axis specificationGO:000979840.011
positive regulation of peptide hormone secretionGO:0090277500.011
single organism behaviorGO:00447081300.011
cell growthGO:00160491040.011
positive regulation of neuron differentiationGO:00456661260.011
response to fatty acidGO:0070542650.011
negative regulation of response to external stimulusGO:0032102370.011
purine nucleoside metabolic processGO:00422781690.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
positive regulation of humoral immune responseGO:000292220.011
negative regulation of rna biosynthetic processGO:19026791180.011
reactive nitrogen species metabolic processGO:200105710.011
calcium ion importGO:0070509220.011
toxin transportGO:190199830.011
lipid localizationGO:0010876620.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
regulation of catabolic processGO:00098941130.011
amide biosynthetic processGO:0043604100.010
cellular macromolecular complex assemblyGO:0034622580.010
positive regulation of protein kinase activityGO:0045860730.010
negative regulation of protein modification processGO:0031400520.010
heart developmentGO:0007507720.010
regulation of synaptic plasticityGO:0048167700.010
regulation of cellular component biogenesisGO:0044087860.010
chemical homeostasisGO:00488782920.010
monocarboxylic acid metabolic processGO:00327871520.010
positive regulation of circadian sleep wake cycle sleepGO:004593890.010
response to dexamethasoneGO:0071548490.010
epithelial cell migrationGO:0010631190.010
hormone transportGO:00099141210.010
sleepGO:0030431300.010
catenin import into nucleusGO:003541110.010
protein catabolic processGO:0030163300.010
regulation of peptide secretionGO:0002791820.010
cell motilityGO:00488702020.010
positive regulation of cellular protein metabolic processGO:00322701670.010
regulation of growthGO:00400081050.010
reactive oxygen species biosynthetic processGO:190340980.010
adaptive immune responseGO:0002250140.010

Itih4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.152
hematopoietic system diseaseDOID:7400.152
inherited blood coagulation diseaseDOID:221400.152
blood coagulation diseaseDOID:124700.152
disease of anatomical entityDOID:700.152
disease of metabolismDOID:001466700.038
Human
cardiovascular system diseaseDOID:128700.035
inherited metabolic disorderDOID:65500.018
Human
vascular diseaseDOID:17800.017
artery diseaseDOID:005082800.015
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
gastrointestinal system cancerDOID:311900.011
cerebrovascular diseaseDOID:671300.011
nervous system diseaseDOID:86300.011