IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Sfrs9

splicing factor, arginine/serine-rich 9

(Aliases: MGC105562,Srsf9)

Ensembl: ENSRNOG00000001163
RGD: 1309495
Entrez: 288701
UniProtKB: Q5PPI1

Process Predictions
Disease Predictions

Sfrs9 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rna metabolic process	GO:0016070	406	0.280	Human Yeast
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.162	Human Yeast
transcription from rna polymerase ii promoter	GO:0006366	252	0.158	Yeast
negative regulation of metabolic process	GO:0009892	331	0.134	Human Yeast
regulation of rna metabolic process	GO:0051252	391	0.128	Human Yeast
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.114	Human Yeast
negative regulation of macromolecule metabolic process	GO:0010605	260	0.112	Human Yeast
negative regulation of rna metabolic process	GO:0051253	123	0.107	Human Yeast
regulation of protein metabolic process	GO:0051246	289	0.105	Yeast
single organism organelle organization	GO:1902589	180	0.104
regulation of cellular protein metabolic process	GO:0032268	267	0.083	Yeast
nucleic acid templated transcription	GO:0097659	379	0.079	Yeast
negative regulation of cellular metabolic process	GO:0031324	281	0.077	Human Yeast
transcription dna templated	GO:0006351	377	0.071	Yeast
organelle organization	GO:0006996	266	0.069
cytoskeleton organization	GO:0007010	111	0.062
regulation of nucleic acid templated transcription	GO:1903506	380	0.060	Yeast
cellular ketone metabolic process	GO:0042180	51	0.060
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.055	Yeast
anatomical structure morphogenesis	GO:0009653	298	0.055
negative regulation of biosynthetic process	GO:0009890	168	0.052	Yeast
negative regulation of cellular biosynthetic process	GO:0031327	161	0.050	Yeast
cellular response to stress	GO:0033554	269	0.047	Fly
multicellular organism reproduction	GO:0032504	233	0.047
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.046	Yeast
multi organism reproductive process	GO:0044703	262	0.045
reproductive process	GO:0022414	372	0.045
regulation of transcription dna templated	GO:0006355	374	0.044	Yeast
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.040	Yeast
negative regulation of transcription dna templated	GO:0045892	116	0.038	Yeast
regulation of rna biosynthetic process	GO:2001141	381	0.038	Yeast
intracellular signal transduction	GO:0035556	314	0.038
gamete generation	GO:0007276	124	0.037
cellular amino acid metabolic process	GO:0006520	107	0.036
single organism reproductive process	GO:0044702	297	0.035
amine metabolic process	GO:0009308	38	0.034
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.034	Yeast
programmed cell death	GO:0012501	392	0.033
multicellular organismal reproductive process	GO:0048609	233	0.033
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.033	Yeast
positive regulation of rna metabolic process	GO:0051254	203	0.032	Yeast
regulation of molecular function	GO:0065009	398	0.031
reproduction	GO:0000003	245	0.031
positive regulation of cellular protein metabolic process	GO:0032270	167	0.031
cellular amine metabolic process	GO:0044106	38	0.030
negative regulation of gene expression	GO:0010629	199	0.030	Human Yeast
cellular component biogenesis	GO:0044085	368	0.030
regulation of phosphate metabolic process	GO:0019220	349	0.030
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.029	Yeast
carboxylic acid metabolic process	GO:0019752	289	0.029
cell projection organization	GO:0030030	302	0.029
regulation of phosphorus metabolic process	GO:0051174	349	0.029
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.028	Yeast
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.028	Yeast
rna biosynthetic process	GO:0032774	380	0.028	Yeast
protein phosphorylation	GO:0006468	345	0.028
central nervous system development	GO:0007417	311	0.028
regulation of cell differentiation	GO:0045595	320	0.028
head development	GO:0060322	247	0.027
regulation of cellular amino acid metabolic process	GO:0006521	2	0.027
positive regulation of phosphorus metabolic process	GO:0010562	262	0.027
neuron differentiation	GO:0030182	368	0.027
tissue development	GO:0009888	252	0.027
cell morphogenesis involved in differentiation	GO:0000904	119	0.027
brain development	GO:0007420	247	0.027
regulation of cellular localization	GO:0060341	263	0.027
developmental process involved in reproduction	GO:0003006	159	0.027
negative regulation of rna biosynthetic process	GO:1902679	118	0.026	Yeast
regulation of cellular amine metabolic process	GO:0033238	8	0.026
regulation of cellular component organization	GO:0051128	368	0.026	Yeast
oxoacid metabolic process	GO:0043436	290	0.026
apoptotic process	GO:0006915	381	0.026
positive regulation of multicellular organismal process	GO:0051240	387	0.026
protein localization	GO:0008104	191	0.026
positive regulation of signal transduction	GO:0009967	175	0.025
cellular component morphogenesis	GO:0032989	155	0.025
positive regulation of gene expression	GO:0010628	244	0.025	Yeast
negative regulation of cell communication	GO:0010648	158	0.025
cell cycle	GO:0007049	101	0.024	Fly
rhythmic process	GO:0048511	156	0.024
sexual reproduction	GO:0019953	148	0.024
positive regulation of nervous system development	GO:0051962	178	0.024
regulation of apoptotic process	GO:0042981	335	0.024
actin filament based process	GO:0030029	86	0.023
regulation of signal transduction	GO:0009966	318	0.023
regulation of intracellular signal transduction	GO:1902531	218	0.023
behavior	GO:0007610	205	0.023
macromolecular complex subunit organization	GO:0043933	339	0.022	Yeast
regulation of organelle organization	GO:0033043	80	0.022
ribose phosphate metabolic process	GO:0019693	235	0.022
cellular response to endogenous stimulus	GO:0071495	377	0.022
regulation of catalytic activity	GO:0050790	304	0.022
cellular component assembly	GO:0022607	360	0.022
organophosphate metabolic process	GO:0019637	370	0.022
regulation of protein modification process	GO:0031399	194	0.021
regulation of phosphorylation	GO:0042325	248	0.021
protein complex assembly	GO:0006461	263	0.021
response to oxygen levels	GO:0070482	265	0.021
regulation of multicellular organismal development	GO:2000026	376	0.021
organonitrogen compound biosynthetic process	GO:1901566	167	0.021
ion transmembrane transport	GO:0034220	365	0.021
regulation of neurogenesis	GO:0050767	247	0.021
homeostatic process	GO:0042592	331	0.021
cardiovascular system development	GO:0072358	134	0.021
positive regulation of neurogenesis	GO:0050769	165	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.020	Yeast
positive regulation of apoptotic process	GO:0043065	154	0.020
tongue morphogenesis	GO:0043587	3	0.020
protein complex biogenesis	GO:0070271	263	0.020
chemical homeostasis	GO:0048878	292	0.020
cellular response to nitrogen compound	GO:1901699	210	0.020
regulation of cellular ketone metabolic process	GO:0010565	27	0.020
carbohydrate derivative metabolic process	GO:1901135	346	0.020
response to testosterone	GO:0033574	55	0.020
cell part morphogenesis	GO:0032990	123	0.019
cellular response to organonitrogen compound	GO:0071417	197	0.019
positive regulation of cell communication	GO:0010647	271	0.019
positive regulation of cell differentiation	GO:0045597	217	0.019
positive regulation of phosphate metabolic process	GO:0045937	262	0.019
regulation of anatomical structure size	GO:0090066	135	0.019
regulation of cell cycle	GO:0051726	73	0.019	Fly
positive regulation of molecular function	GO:0044093	230	0.018
regulation of programmed cell death	GO:0043067	341	0.018
response to alkaloid	GO:0043279	132	0.018
organic acid metabolic process	GO:0006082	292	0.018
negative regulation of protein metabolic process	GO:0051248	114	0.018	Yeast
positive regulation of catalytic activity	GO:0043085	184	0.018
response to peptide hormone	GO:0043434	278	0.018
wound healing	GO:0042060	122	0.018
ribose phosphate biosynthetic process	GO:0046390	87	0.017
cellular macromolecule localization	GO:0070727	122	0.017
regulation of peptide hormone secretion	GO:0090276	80	0.017
neuron development	GO:0048666	286	0.017
macromolecule localization	GO:0033036	252	0.017	Yeast
carbohydrate derivative biosynthetic process	GO:1901137	124	0.017
response to ketone	GO:1901654	182	0.017
nucleoside phosphate metabolic process	GO:0006753	283	0.017
regulation of nervous system development	GO:0051960	264	0.016
response to wounding	GO:0009611	254	0.016
positive regulation of rna biosynthetic process	GO:1902680	197	0.016	Yeast
axis specification	GO:0009798	4	0.016
regulation of neuron differentiation	GO:0045664	208	0.016
positive regulation of intracellular signal transduction	GO:1902533	138	0.016
regulation of neuron death	GO:1901214	115	0.016
regulation of body fluid levels	GO:0050878	90	0.016
positive regulation of cell development	GO:0010720	176	0.016
locomotion	GO:0040011	237	0.016
response to purine containing compound	GO:0014074	126	0.016
spermatogenesis	GO:0007283	99	0.016
negative regulation of cellular protein metabolic process	GO:0032269	106	0.015	Yeast
response to acid chemical	GO:0001101	222	0.015
circadian rhythm	GO:0007623	88	0.015
positive regulation of cell death	GO:0010942	184	0.015
response to decreased oxygen levels	GO:0036293	237	0.015
regulation of secretion by cell	GO:1903530	208	0.015
positive regulation of signaling	GO:0023056	270	0.015
vesicle mediated transport	GO:0016192	181	0.015
cellular homeostasis	GO:0019725	252	0.015
negative regulation of mitotic cell cycle phase transition	GO:1901991	3	0.015	Fly
response to hyperoxia	GO:0055093	45	0.015
positive regulation of biosynthetic process	GO:0009891	319	0.015	Yeast
transmembrane transport	GO:0055085	412	0.015
sex differentiation	GO:0007548	113	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
positive regulation of transcription dna templated	GO:0045893	197	0.014	Yeast
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO:2001269	1	0.014
organ morphogenesis	GO:0009887	75	0.014
protein complex subunit organization	GO:0071822	302	0.014	Yeast
regulation of secretion	GO:0051046	224	0.014
regulation of protein phosphorylation	GO:0001932	183	0.014
nitrogen compound transport	GO:0071705	229	0.014	Yeast
neurological system process	GO:0050877	219	0.014
nucleotide metabolic process	GO:0009117	279	0.014
response to peptide	GO:1901652	292	0.014
positive regulation of neuron differentiation	GO:0045666	126	0.014
response to insulin	GO:0032868	133	0.014
response to cytokine	GO:0034097	215	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
response to lipopolysaccharide	GO:0032496	191	0.013
dna metabolic process	GO:0006259	96	0.013
positive regulation of cell projection organization	GO:0031346	111	0.013
cell cycle checkpoint	GO:0000075	2	0.013	Fly
actin filament organization	GO:0007015	42	0.013
male gamete generation	GO:0048232	99	0.013
regulation of cell cycle process	GO:0010564	31	0.013	Fly
neuron projection development	GO:0031175	273	0.013
eye morphogenesis	GO:0048592	4	0.013
regulation of cell projection organization	GO:0031344	175	0.013
negative regulation of signaling	GO:0023057	157	0.013
positive regulation of programmed cell death	GO:0043068	157	0.013
protein oligomerization	GO:0051259	191	0.013
peptidyl amino acid modification	GO:0018193	126	0.013
positive regulation of developmental process	GO:0051094	283	0.013
organophosphate biosynthetic process	GO:0090407	143	0.013
embryonic appendage morphogenesis	GO:0035113	4	0.013
adult locomotory behavior	GO:0008344	4	0.013
positive regulation of cellular component organization	GO:0051130	200	0.013
response to radiation	GO:0009314	137	0.013
negative regulation of cell cycle phase transition	GO:1901988	4	0.013	Fly
regulation of anatomical structure morphogenesis	GO:0022603	141	0.013
cellular response to oxygen containing compound	GO:1901701	386	0.013
aging	GO:0007568	241	0.013
embryonic limb morphogenesis	GO:0030326	4	0.013
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.012
proteolysis	GO:0006508	175	0.012
ribonucleotide metabolic process	GO:0009259	231	0.012
cellular chemical homeostasis	GO:0055082	247	0.012
nucleoside phosphate biosynthetic process	GO:1901293	102	0.012
actin cytoskeleton organization	GO:0030036	73	0.012
ribonucleotide biosynthetic process	GO:0009260	85	0.012
ion homeostasis	GO:0050801	212	0.012
cytoplasmic transport	GO:0016482	115	0.012	Yeast
growth	GO:0040007	165	0.012
regulation of viral transcription	GO:0046782	2	0.012
cell adhesion	GO:0007155	110	0.012
muscle structure development	GO:0061061	87	0.012
posttranscriptional regulation of gene expression	GO:0010608	37	0.012	Yeast
macromolecular complex assembly	GO:0065003	273	0.011
neuron projection morphogenesis	GO:0048812	122	0.011
regulation of cell development	GO:0060284	263	0.011
regulation of growth	GO:0040008	105	0.011
regulation of establishment of planar polarity	GO:0090175	2	0.011
epithelial cell differentiation	GO:0030855	71	0.011
negative regulation of multicellular organismal process	GO:0051241	203	0.011
protein transport	GO:0015031	132	0.011
circulatory system development	GO:0072359	134	0.011
purine nucleotide biosynthetic process	GO:0006164	83	0.011
dna integrity checkpoint	GO:0031570	2	0.011	Fly
negative regulation of peptide hormone secretion	GO:0090278	30	0.011
cellular protein localization	GO:0034613	122	0.011
cell cycle process	GO:0022402	57	0.011	Fly
cell morphogenesis	GO:0000902	142	0.011
g protein coupled receptor signaling pathway	GO:0007186	242	0.011
purine ribonucleotide metabolic process	GO:0009150	227	0.011
bmp signaling pathway	GO:0030509	4	0.011
establishment of protein localization	GO:0045184	141	0.011
positive regulation of cellular biosynthetic process	GO:0031328	295	0.011	Yeast
anion transport	GO:0006820	178	0.011
negative regulation of viral process	GO:0048525	4	0.011
activation of cysteine type endopeptidase activity	GO:0097202	4	0.011
response to growth factor	GO:0070848	189	0.011
purine nucleotide metabolic process	GO:0006163	229	0.010
negative regulation of signal transduction	GO:0009968	83	0.010
spindle organization	GO:0007051	2	0.010
single organism behavior	GO:0044708	130	0.010
response to nutrient levels	GO:0031667	370	0.010
secretion	GO:0046903	307	0.010
regulation of cellular response to stress	GO:0080135	49	0.010
biological adhesion	GO:0022610	110	0.010
secretion by cell	GO:0032940	248	0.010
cellular catabolic process	GO:0044248	295	0.010	Yeast
purine ribonucleotide biosynthetic process	GO:0009152	81	0.010
inorganic ion transmembrane transport	GO:0098660	229	0.010
response to hypoxia	GO:0001666	231	0.010
positive regulation of protein metabolic process	GO:0051247	178	0.010
regulation of canonical wnt signaling pathway	GO:0060828	4	0.010

Sfrs9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.031
disease of anatomical entity	DOID:7	0.031
central nervous system disease	DOID:331	0.013
intestinal cancer	DOID:10155	0.013
gastrointestinal system cancer	DOID:3119	0.013
colon cancer	DOID:219	0.013
large intestine cancer	DOID:5672	0.013
colon carcinoma	DOID:1520	0.013
colorectal cancer	DOID:9256	0.013
cancer	DOID:162	0.013
organ system cancer	DOID:0050686	0.013
disease of cellular proliferation	DOID:14566	0.013

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