IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Chst1

carbohydrate (keratan sulfate Gal-6) sulfotransferase 1

RGD: 1308142
Entrez: 295934
Ensembl: ENSRNOG00000007989
UniProtKB: Q5RJQ0

Process Predictions
Disease Predictions

Chst1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of phosphorus metabolic process	GO:0051174	349	0.065
apoptotic process	GO:0006915	381	0.061
intracellular signal transduction	GO:0035556	314	0.059
programmed cell death	GO:0012501	392	0.058
cell projection organization	GO:0030030	302	0.051	Rat
rna biosynthetic process	GO:0032774	380	0.049
regulation of signal transduction	GO:0009966	318	0.047
regulation of phosphate metabolic process	GO:0019220	349	0.046
neuron projection development	GO:0031175	273	0.046	Rat
regulation of catalytic activity	GO:0050790	304	0.046
protein phosphorylation	GO:0006468	345	0.046
organic acid metabolic process	GO:0006082	292	0.045	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.045
neuron development	GO:0048666	286	0.042	Rat
positive regulation of molecular function	GO:0044093	230	0.042
carboxylic acid metabolic process	GO:0019752	289	0.041
regulation of protein metabolic process	GO:0051246	289	0.040
reproductive process	GO:0022414	372	0.040
negative regulation of signaling	GO:0023057	157	0.040
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.039
regulation of molecular function	GO:0065009	398	0.039
regulation of apoptotic process	GO:0042981	335	0.038
regulation of cellular protein metabolic process	GO:0032268	267	0.038
positive regulation of phosphate metabolic process	GO:0045937	262	0.037
negative regulation of cellular metabolic process	GO:0031324	281	0.037
negative regulation of metabolic process	GO:0009892	331	0.037
negative regulation of macromolecule metabolic process	GO:0010605	260	0.037
regulation of rna biosynthetic process	GO:2001141	381	0.037
regulation of nucleic acid templated transcription	GO:1903506	380	0.036
regulation of cellular amino acid metabolic process	GO:0006521	2	0.036
cellular response to endogenous stimulus	GO:0071495	377	0.036
regulation of phosphorylation	GO:0042325	248	0.036
positive regulation of phosphorylation	GO:0042327	177	0.035
amine metabolic process	GO:0009308	38	0.035
nucleic acid templated transcription	GO:0097659	379	0.035
regulation of rna metabolic process	GO:0051252	391	0.034
neuron differentiation	GO:0030182	368	0.034	Rat
cellular response to oxygen containing compound	GO:1901701	386	0.034
lipid metabolic process	GO:0006629	283	0.034
regulation of nervous system development	GO:0051960	264	0.034
positive regulation of catalytic activity	GO:0043085	184	0.034
macromolecular complex subunit organization	GO:0043933	339	0.033
negative regulation of cellular biosynthetic process	GO:0031327	161	0.033
cation transmembrane transport	GO:0098655	263	0.033
organophosphate metabolic process	GO:0019637	370	0.033
cellular ketone metabolic process	GO:0042180	51	0.033
cellular amine metabolic process	GO:0044106	38	0.033
regulation of protein modification process	GO:0031399	194	0.032
negative regulation of biosynthetic process	GO:0009890	168	0.032
organic substance catabolic process	GO:1901575	316	0.032
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.032
negative regulation of cell communication	GO:0010648	158	0.031
response to growth factor	GO:0070848	189	0.031
regulation of transcription dna templated	GO:0006355	374	0.031
metal ion transport	GO:0030001	289	0.031
catabolic process	GO:0009056	351	0.031
transcription from rna polymerase ii promoter	GO:0006366	252	0.031
cellular amino acid metabolic process	GO:0006520	107	0.031
regulation of multicellular organismal development	GO:2000026	376	0.031
response to extracellular stimulus	GO:0009991	380	0.031
regulation of programmed cell death	GO:0043067	341	0.031
positive regulation of phosphorus metabolic process	GO:0010562	262	0.030
regulation of cellular component organization	GO:0051128	368	0.030
regulation of intracellular signal transduction	GO:1902531	218	0.030
regulation of cellular amine metabolic process	GO:0033238	8	0.030
central nervous system development	GO:0007417	311	0.029
positive regulation of developmental process	GO:0051094	283	0.029
positive regulation of multicellular organismal process	GO:0051240	387	0.029
transcription dna templated	GO:0006351	377	0.029
chemical homeostasis	GO:0048878	292	0.029
regulation of cellular ketone metabolic process	GO:0010565	27	0.028
head development	GO:0060322	247	0.027
transmembrane transport	GO:0055085	412	0.027
nitrogen compound transport	GO:0071705	229	0.027
nucleobase containing small molecule metabolic process	GO:0055086	316	0.027
positive regulation of biosynthetic process	GO:0009891	319	0.027
negative regulation of gene expression	GO:0010629	199	0.027
positive regulation of protein metabolic process	GO:0051247	178	0.027
single organism catabolic process	GO:0044712	283	0.026
positive regulation of cellular biosynthetic process	GO:0031328	295	0.026
cation transport	GO:0006812	382	0.026
regulation of hydrolase activity	GO:0051336	143	0.026
rna metabolic process	GO:0016070	406	0.025
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.025
homeostatic process	GO:0042592	331	0.025
positive regulation of rna metabolic process	GO:0051254	203	0.025
regulation of ion transport	GO:0043269	245	0.025
negative regulation of cell death	GO:0060548	229	0.025
cellular response to nitrogen compound	GO:1901699	210	0.025
small gtpase mediated signal transduction	GO:0007264	36	0.024
negative regulation of response to stimulus	GO:0048585	155	0.024
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.024
single organism reproductive process	GO:0044702	297	0.024
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.024
ras protein signal transduction	GO:0007265	29	0.024
response to nutrient levels	GO:0031667	370	0.024
oxoacid metabolic process	GO:0043436	290	0.024	Human
mapk cascade	GO:0000165	140	0.024
ribose phosphate metabolic process	GO:0019693	235	0.023
carbohydrate derivative metabolic process	GO:1901135	346	0.023	Human
regulation of neurogenesis	GO:0050767	247	0.023
positive regulation of gene expression	GO:0010628	244	0.023
cellular calcium ion homeostasis	GO:0006874	160	0.023
carbohydrate metabolic process	GO:0005975	130	0.023	Human
cellular catabolic process	GO:0044248	295	0.023
positive regulation of cell proliferation	GO:0008284	249	0.023
negative regulation of programmed cell death	GO:0043069	183	0.023
cellular ion homeostasis	GO:0006873	184	0.022
carboxylic acid transport	GO:0046942	115	0.022
regulation of cell proliferation	GO:0042127	359	0.022
reproduction	GO:0000003	245	0.022
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.022
protein complex subunit organization	GO:0071822	302	0.022
regulation of protein phosphorylation	GO:0001932	183	0.022
protein complex biogenesis	GO:0070271	263	0.022
cellular component biogenesis	GO:0044085	368	0.022
cellular response to stress	GO:0033554	269	0.022	Rat
negative regulation of apoptotic process	GO:0043066	181	0.022
protein complex assembly	GO:0006461	263	0.021
cellular component assembly	GO:0022607	360	0.021
response to oxygen levels	GO:0070482	265	0.021
ion homeostasis	GO:0050801	212	0.021
positive regulation of protein phosphorylation	GO:0001934	135	0.021
cellular response to growth factor stimulus	GO:0071363	162	0.021
regulation of cell differentiation	GO:0045595	320	0.021
multicellular organismal reproductive process	GO:0048609	233	0.021
response to peptide	GO:1901652	292	0.021
regulation of transferase activity	GO:0051338	123	0.021
regulation of hormone levels	GO:0010817	187	0.021
cell cell signaling	GO:0007267	335	0.021
secretion	GO:0046903	307	0.021
inorganic cation transmembrane transport	GO:0098662	202	0.021
regulation of system process	GO:0044057	208	0.021
ribonucleotide metabolic process	GO:0009259	231	0.021
positive regulation of rna biosynthetic process	GO:1902680	197	0.021
cellular chemical homeostasis	GO:0055082	247	0.021
positive regulation of cellular amine metabolic process	GO:0033240	3	0.020
regulation of secretion by cell	GO:1903530	208	0.020
cellular homeostasis	GO:0019725	252	0.020
positive regulation of cellular protein metabolic process	GO:0032270	167	0.020
regulation of kinase activity	GO:0043549	117	0.020
macromolecular complex assembly	GO:0065003	273	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.020
multicellular organism reproduction	GO:0032504	233	0.020
regulation of cellular catabolic process	GO:0031329	101	0.020
cellular response to hormone stimulus	GO:0032870	247	0.020
brain development	GO:0007420	247	0.020
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.019
nucleotide metabolic process	GO:0009117	279	0.019
positive regulation of protein kinase activity	GO:0045860	73	0.019
developmental process involved in reproduction	GO:0003006	159	0.019
cellular lipid metabolic process	GO:0044255	208	0.019
regulation of metal ion transport	GO:0010959	118	0.019
circulatory system process	GO:0003013	183	0.019
negative regulation of signal transduction	GO:0009968	83	0.019
anatomical structure morphogenesis	GO:0009653	298	0.019
negative regulation of molecular function	GO:0044092	133	0.019
organelle organization	GO:0006996	266	0.019
muscle system process	GO:0003012	115	0.019
positive regulation of cell communication	GO:0010647	271	0.019
negative regulation of rna metabolic process	GO:0051253	123	0.018
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.018
positive regulation of cell differentiation	GO:0045597	217	0.018
regulation of catabolic process	GO:0009894	113	0.018
response to cytokine	GO:0034097	215	0.018
anion transport	GO:0006820	178	0.018
single organism carbohydrate metabolic process	GO:0044723	118	0.018	Human
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.018
purine containing compound metabolic process	GO:0072521	253	0.018
hormone transport	GO:0009914	121	0.018
regulation of secretion	GO:0051046	224	0.018
positive regulation of signaling	GO:0023056	270	0.018
response to wounding	GO:0009611	254	0.018	Rat
metal ion homeostasis	GO:0055065	186	0.018
positive regulation of kinase activity	GO:0033674	77	0.018
synaptic transmission	GO:0007268	235	0.018
chromosome segregation	GO:0007059	2	0.018
multi organism reproductive process	GO:0044703	262	0.017
response to peptide hormone	GO:0043434	278	0.017
inorganic ion transmembrane transport	GO:0098660	229	0.017
cellular response to organonitrogen compound	GO:0071417	197	0.017
regulation of cell development	GO:0060284	263	0.017
positive regulation of protein modification process	GO:0031401	142	0.017
negative regulation of neurogenesis	GO:0050768	78	0.017
positive regulation of response to stimulus	GO:0048584	285	0.017
negative regulation of rna biosynthetic process	GO:1902679	118	0.017
cellular metal ion homeostasis	GO:0006875	172	0.017
regulation of anatomical structure size	GO:0090066	135	0.017
secretion by cell	GO:0032940	248	0.017
peptidyl amino acid modification	GO:0018193	126	0.017
heterocycle catabolic process	GO:0046700	167	0.017
organophosphate catabolic process	GO:0046434	148	0.017
purine ribonucleoside metabolic process	GO:0046128	168	0.016
cellular response to lipid	GO:0071396	201	0.016
cation homeostasis	GO:0055080	195	0.016
positive regulation of intracellular signal transduction	GO:1902533	138	0.016
cellular cation homeostasis	GO:0030003	180	0.016
response to decreased oxygen levels	GO:0036293	237	0.016
regulation of canonical wnt signaling pathway	GO:0060828	4	0.016
positive regulation of transcription dna templated	GO:0045893	197	0.016
nucleoside phosphate metabolic process	GO:0006753	283	0.016
single organism biosynthetic process	GO:0044711	342	0.016
regulation of cellular component movement	GO:0051270	150	0.016	Rat
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.016
response to nutrient	GO:0007584	248	0.016
cellular response to peptide	GO:1901653	133	0.016
calcium ion homeostasis	GO:0055074	162	0.016
cell motility	GO:0048870	202	0.016
positive regulation of transport	GO:0051050	245	0.016
regulation of protein kinase activity	GO:0045859	105	0.016
nucleoside phosphate catabolic process	GO:1901292	140	0.016
negative regulation of phosphate metabolic process	GO:0045936	80	0.016
organonitrogen compound catabolic process	GO:1901565	179	0.015
organic cyclic compound catabolic process	GO:1901361	175	0.015
g protein coupled receptor signaling pathway	GO:0007186	242	0.015
sexual reproduction	GO:0019953	148	0.015
negative regulation of protein metabolic process	GO:0051248	114	0.015
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.015
cellular component movement	GO:0006928	248	0.015	Rat
monovalent inorganic cation transport	GO:0015672	172	0.015
carbohydrate derivative catabolic process	GO:1901136	147	0.015
nucleoside metabolic process	GO:0009116	179	0.015
signal transduction by phosphorylation	GO:0023014	144	0.015
response to hypoxia	GO:0001666	231	0.015
regulation of neuron projection development	GO:0010975	161	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.015
cytosolic calcium ion homeostasis	GO:0051480	140	0.015
organic anion transport	GO:0015711	132	0.015
cellular response to organic cyclic compound	GO:0071407	202	0.015
anterior posterior pattern specification	GO:0009952	1	0.015
negative regulation of multicellular organismal process	GO:0051241	203	0.014
regulation of cell projection organization	GO:0031344	175	0.014
lipid biosynthetic process	GO:0008610	128	0.014
divalent inorganic cation transport	GO:0072511	134	0.014
calcium ion transport	GO:0006816	131	0.014
axis specification	GO:0009798	4	0.014
positive regulation of cellular component movement	GO:0051272	102	0.014	Rat
negative regulation of catalytic activity	GO:0043086	103	0.014
glycosyl compound metabolic process	GO:1901657	182	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.014
mitotic spindle organization	GO:0007052	2	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
negative regulation of cell differentiation	GO:0045596	99	0.014
response to corticosteroid	GO:0031960	235	0.014
response to carbohydrate	GO:0009743	183	0.014
cellular response to cytokine stimulus	GO:0071345	127	0.014
positive regulation of cell projection organization	GO:0031346	111	0.014
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.014
positive regulation of cell death	GO:0010942	184	0.014
ribonucleoside metabolic process	GO:0009119	174	0.014
cellular nitrogen compound catabolic process	GO:0044270	163	0.014
nucleobase containing compound catabolic process	GO:0034655	152	0.014
divalent inorganic cation homeostasis	GO:0072507	165	0.013
cell migration	GO:0016477	197	0.013
heart morphogenesis	GO:0003007	3	0.013
purine ribonucleotide catabolic process	GO:0009154	136	0.013
negative regulation of phosphorus metabolic process	GO:0010563	80	0.013
regulation of neuron differentiation	GO:0045664	208	0.013
response to oxidative stress	GO:0006979	186	0.013
locomotion	GO:0040011	237	0.013
response to acid chemical	GO:0001101	222	0.013
positive regulation of neurogenesis	GO:0050769	165	0.013
regulation of cell migration	GO:0030334	128	0.013
response to monosaccharide	GO:0034284	159	0.013
positive regulation of signal transduction	GO:0009967	175	0.013
regulation of membrane potential	GO:0042391	110	0.013
negative regulation of cell development	GO:0010721	82	0.013
organic acid transport	GO:0015849	116	0.013
positive regulation of secretion by cell	GO:1903532	128	0.013
purine nucleotide metabolic process	GO:0006163	229	0.013
regeneration	GO:0031099	163	0.013	Rat
regulation of proteasomal protein catabolic process	GO:0061136	4	0.013
response to ketone	GO:1901654	182	0.013
reactive oxygen species biosynthetic process	GO:1903409	8	0.013
cell morphogenesis involved in differentiation	GO:0000904	119	0.013
localization of cell	GO:0051674	202	0.013
negative regulation of nervous system development	GO:0051961	79	0.013
response to purine containing compound	GO:0014074	126	0.013
behavior	GO:0007610	205	0.013
ion transmembrane transport	GO:0034220	365	0.013
positive regulation of transferase activity	GO:0051347	81	0.013
response to glucose	GO:0009749	136	0.013
cell cycle	GO:0007049	101	0.013
amide transport	GO:0042886	105	0.013
purine ribonucleotide metabolic process	GO:0009150	227	0.013
neuron projection morphogenesis	GO:0048812	122	0.012
regulation of cytoskeleton organization	GO:0051493	49	0.012
neural crest cell development	GO:0014032	2	0.012
regulation of purine nucleotide metabolic process	GO:1900542	115	0.012
divalent metal ion transport	GO:0070838	132	0.012
positive regulation of nervous system development	GO:0051962	178	0.012
response to reactive oxygen species	GO:0000302	120	0.012
response to inorganic substance	GO:0010035	377	0.012
negative regulation of transcription dna templated	GO:0045892	116	0.012
reactive nitrogen species metabolic process	GO:2001057	1	0.012
gamete generation	GO:0007276	124	0.012
regulation of gtpase activity	GO:0043087	57	0.012
cell cycle checkpoint	GO:0000075	2	0.012
circulatory system development	GO:0072359	134	0.012
response to hexose	GO:0009746	144	0.012
embryonic pattern specification	GO:0009880	1	0.012
cellular response to acid chemical	GO:0071229	75	0.012
cellular response to external stimulus	GO:0071496	118	0.012
dephosphorylation	GO:0016311	98	0.012
positive regulation of mapk cascade	GO:0043410	92	0.012
ribonucleotide catabolic process	GO:0009261	136	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.012
response to vitamin	GO:0033273	131	0.012
eye morphogenesis	GO:0048592	4	0.012
rho protein signal transduction	GO:0007266	11	0.012
negative regulation of cellular protein metabolic process	GO:0032269	106	0.012
purine nucleoside metabolic process	GO:0042278	169	0.012
peptide transport	GO:0015833	97	0.012
bmp signaling pathway	GO:0030509	4	0.012
regulation of nucleotide catabolic process	GO:0030811	65	0.012
regulation of nucleotide metabolic process	GO:0006140	117	0.012
regulation of locomotion	GO:0040012	148	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.011
blood circulation	GO:0008015	183	0.011
regulation of cell cycle	GO:0051726	73	0.011
carbohydrate catabolic process	GO:0016052	40	0.011
nucleotide catabolic process	GO:0009166	139	0.011
erk1 and erk2 cascade	GO:0070371	48	0.011
positive regulation of neuron differentiation	GO:0045666	126	0.011
tissue development	GO:0009888	252	0.011
negative regulation of canonical wnt signaling pathway	GO:0090090	4	0.011
gastrulation	GO:0007369	2	0.011
reactive oxygen species metabolic process	GO:0072593	37	0.011
growth	GO:0040007	165	0.011
response to estrogen	GO:0043627	232	0.011
positive regulation of catabolic process	GO:0009896	78	0.011
positive regulation of cell development	GO:0010720	176	0.011
defense response	GO:0006952	194	0.011
proteolysis	GO:0006508	175	0.011
guanosine containing compound catabolic process	GO:1901069	71	0.011
positive regulation of gtp catabolic process	GO:0033126	48	0.011
sequestering of metal ion	GO:0051238	9	0.011
regulation of cellular localization	GO:0060341	263	0.011
regulation of nucleoside metabolic process	GO:0009118	66	0.011
purine nucleotide catabolic process	GO:0006195	136	0.011
reproductive structure development	GO:0048608	128	0.011
aromatic compound catabolic process	GO:0019439	168	0.011
regulation of lipid metabolic process	GO:0019216	68	0.011
neural crest cell differentiation	GO:0014033	2	0.011
vesicle mediated transport	GO:0016192	181	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.011
regulation of muscle system process	GO:0090257	79	0.011
single organism intracellular transport	GO:1902582	166	0.011
cell type specific apoptotic process	GO:0097285	134	0.011
peptidyl tyrosine modification	GO:0018212	72	0.011
peptidyl tyrosine phosphorylation	GO:0018108	72	0.011
immune system process	GO:0002376	204	0.011
synaptic growth at neuromuscular junction	GO:0051124	1	0.011
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.011
regulation of peptide secretion	GO:0002791	82	0.011
regulation of cell growth	GO:0001558	85	0.010
spindle organization	GO:0007051	2	0.010
regulation of synaptic transmission	GO:0050804	141	0.010
regulation of purine nucleotide catabolic process	GO:0033121	65	0.010
positive regulation of programmed cell death	GO:0043068	157	0.010
response to insulin	GO:0032868	133	0.010
intracellular transport	GO:0046907	185	0.010
regulation of tube size	GO:0035150	89	0.010
regulation of blood circulation	GO:1903522	110	0.010
camera type eye morphogenesis	GO:0048593	2	0.010
cytoskeleton organization	GO:0007010	111	0.010
regulation of stem cell differentiation	GO:2000736	2	0.010
regulation of mapk cascade	GO:0043408	116	0.010
negative regulation of developmental process	GO:0051093	125	0.010
regulation of body fluid levels	GO:0050878	90	0.010
neurological system process	GO:0050877	219	0.010
regulation of homeostatic process	GO:0032844	101	0.010
cell morphogenesis	GO:0000902	142	0.010
cell growth	GO:0016049	104	0.010
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.010
purine containing compound catabolic process	GO:0072523	138	0.010
cellular response to peptide hormone stimulus	GO:0071375	120	0.010

Chst1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.028
nervous system disease	DOID:863	0.028
disease of metabolism	DOID:0014667	0.013
gastrointestinal system disease	DOID:77	0.012

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