Rattus norvegicus

0 known processes

Plekhg3

pleckstrin homology domain containing, family G (with RhoGef domain) member 3

(Aliases: RGD1308089)

Plekhg3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure morphogenesisGO:00096532980.094
neuron differentiationGO:00301823680.076
regulation of cell differentiationGO:00455953200.066
neuron developmentGO:00486662860.062
regulation of signal transductionGO:00099663180.061
regulation of cell developmentGO:00602842630.061
cellular component movementGO:00069282480.056
regulation of anatomical structure morphogenesisGO:00226031410.055
positive regulation of multicellular organismal processGO:00512403870.055
central nervous system developmentGO:00074173110.052
regulation of molecular functionGO:00650093980.052
cell morphogenesis involved in neuron differentiationGO:00486671060.052
regulation of nervous system developmentGO:00519602640.052
cell projection organizationGO:00300303020.049
regulation of neurogenesisGO:00507672470.049
positive regulation of nitrogen compound metabolic processGO:00511733340.048
regulation of cellular component organizationGO:00511283680.048
amine metabolic processGO:0009308380.048
intracellular signal transductionGO:00355563140.047
positive regulation of developmental processGO:00510942830.045
regulation of neuron differentiationGO:00456642080.044
regulation of phosphorus metabolic processGO:00511743490.044
organic acid metabolic processGO:00060822920.044
cell morphogenesis involved in differentiationGO:00009041190.044
catabolic processGO:00090563510.043
negative regulation of metabolic processGO:00098923310.043
positive regulation of neurogenesisGO:00507691650.042
regulation of cell projection organizationGO:00313441750.042
regulation of neuron projection developmentGO:00109751610.041
neuron projection developmentGO:00311752730.041
lipid metabolic processGO:00066292830.040
organophosphate metabolic processGO:00196373700.040
regulation of transcription dna templatedGO:00063553740.040
tissue developmentGO:00098882520.039
head developmentGO:00603222470.038
cellular response to endogenous stimulusGO:00714953770.038
positive regulation of phosphate metabolic processGO:00459372620.037
cellular amino acid metabolic processGO:00065201070.037
rna biosynthetic processGO:00327743800.036
regulation of rna metabolic processGO:00512523910.036
regulation of multicellular organismal developmentGO:20000263760.036
positive regulation of cell developmentGO:00107201760.036
regulation of phosphorylationGO:00423252480.035
transcription dna templatedGO:00063513770.035
secretionGO:00469033070.035
positive regulation of cell differentiationGO:00455972170.035
programmed cell deathGO:00125013920.035
carboxylic acid metabolic processGO:00197522890.035
regulation of proteasomal protein catabolic processGO:006113640.035
oxoacid metabolic processGO:00434362900.035
apoptotic processGO:00069153810.035
cellular amine metabolic processGO:0044106380.034
negative regulation of cell communicationGO:00106481580.034
regulation of phosphate metabolic processGO:00192203490.034
regulation of rna biosynthetic processGO:20011413810.034
regulation of programmed cell deathGO:00430673410.034
regulation of canonical wnt signaling pathwayGO:006082840.033
regulation of cellular amino acid metabolic processGO:000652120.033
single organism catabolic processGO:00447122830.033
regulation of protein metabolic processGO:00512462890.033
positive regulation of phosphorus metabolic processGO:00105622620.033
protein complex subunit organizationGO:00718223020.033
cellular component morphogenesisGO:00329891550.032
regulation of cellular amine metabolic processGO:003323880.032
regulation of apoptotic processGO:00429813350.032
carbohydrate derivative metabolic processGO:19011353460.031
nucleic acid templated transcriptionGO:00976593790.031
regulation of intracellular signal transductionGO:19025312180.031
positive regulation of cellular component organizationGO:00511302000.031
cellular component assemblyGO:00226073600.030
organic substance catabolic processGO:19015753160.030
negative regulation of multicellular organismal processGO:00512412030.030
single organism organelle organizationGO:19025891800.029
nucleobase containing small molecule metabolic processGO:00550863160.029
cellular component biogenesisGO:00440853680.029
cell motilityGO:00488702020.029
negative regulation of cellular metabolic processGO:00313242810.029
brain developmentGO:00074202470.029
positive regulation of nervous system developmentGO:00519621780.029
mesoderm developmentGO:000749820.029
cellular response to oxygen containing compoundGO:19017013860.029
positive regulation of macromolecule biosynthetic processGO:00105572470.028
positive regulation of signalingGO:00230562700.028
cellular lipid metabolic processGO:00442552080.028
response to peptide hormoneGO:00434342780.028
regulation of protein modification processGO:00313991940.027
glycosyl compound catabolic processGO:19016581260.027
organic cyclic compound catabolic processGO:19013611750.027
regulation of nucleic acid templated transcriptionGO:19035063800.026
negative regulation of macromolecule metabolic processGO:00106052600.026
nucleoside metabolic processGO:00091161790.026
regulation of cellular protein metabolic processGO:00322682670.026
regulation of cell proliferationGO:00421273590.026
response to extracellular stimulusGO:00099913800.026
cell morphogenesisGO:00009021420.026
organonitrogen compound catabolic processGO:19015651790.026
single organism biosynthetic processGO:00447113420.025
response to nutrient levelsGO:00316673700.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
axon developmentGO:0061564960.025
rna metabolic processGO:00160704060.025
positive regulation of apoptotic processGO:00430651540.025
positive regulation of biosynthetic processGO:00098913190.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.025
response to oxygen levelsGO:00704822650.025
cellular catabolic processGO:00442482950.025
positive regulation of cell projection organizationGO:00313461110.025
cell migrationGO:00164771970.024
positive regulation of cellular amine metabolic processGO:003324030.024
nucleobase containing compound catabolic processGO:00346551520.024
carbohydrate derivative catabolic processGO:19011361470.024
glycosyl compound metabolic processGO:19016571820.024
cellular ketone metabolic processGO:0042180510.024
cell cell signalingGO:00072673350.024
purine containing compound metabolic processGO:00725212530.024
localization of cellGO:00516742020.024
transcription from rna polymerase ii promoterGO:00063662520.024
synaptic transmissionGO:00072682350.024
positive regulation of cell deathGO:00109421840.023
positive regulation of neuron differentiationGO:00456661260.023
purine ribonucleoside metabolic processGO:00461281680.023
behaviorGO:00076102050.023
response to acid chemicalGO:00011012220.023
ribonucleotide metabolic processGO:00092592310.023
negative regulation of signal transductionGO:0009968830.023
organelle organizationGO:00069962660.022
nitrogen compound transportGO:00717052290.022
small gtpase mediated signal transductionGO:0007264360.022
regulation of system processGO:00440572080.022
gastrulationGO:000736920.022
ribose phosphate metabolic processGO:00196932350.022
nucleotide metabolic processGO:00091172790.022
positive regulation of neuron projection developmentGO:0010976990.022
negative regulation of molecular functionGO:00440921330.021
signal releaseGO:00230611450.021
cellular response to growth factor stimulusGO:00713631620.021
cell part morphogenesisGO:00329901230.021
cellular response to organonitrogen compoundGO:00714171970.021
regulation of cellular ketone metabolic processGO:0010565270.021
cation transportGO:00068123820.021
heterocycle catabolic processGO:00467001670.021
positive regulation of intracellular signal transductionGO:19025331380.021
response to growth factorGO:00708481890.021
transmembrane transportGO:00550854120.021
regulation of protein phosphorylationGO:00019321830.021
positive regulation of signal transductionGO:00099671750.020
single organism reproductive processGO:00447022970.020
epithelium developmentGO:0060429960.020
response to decreased oxygen levelsGO:00362932370.020
purine ribonucleotide metabolic processGO:00091502270.020
purine nucleotide metabolic processGO:00061632290.020
response to peptideGO:19016522920.020
regulation of membrane potentialGO:00423911100.020
nucleoside phosphate catabolic processGO:19012921400.020
positive regulation of transportGO:00510502450.020
positive regulation of molecular functionGO:00440932300.020
motor neuron axon guidanceGO:000804510.020
negative regulation of canonical wnt signaling pathwayGO:009009040.020
positive regulation of programmed cell deathGO:00430681570.020
purine ribonucleoside catabolic processGO:00461301240.020
response to inorganic substanceGO:00100353770.020
aromatic compound catabolic processGO:00194391680.020
protein phosphorylationGO:00064683450.020
cell projection morphogenesisGO:00488581230.020
single organism behaviorGO:00447081300.020
ribonucleoside metabolic processGO:00091191740.019
response to glucocorticoidGO:00513842230.019
gliogenesisGO:0042063930.019
macromolecule localizationGO:00330362520.019
regulation of cellular catabolic processGO:00313291010.019
negative regulation of cellular protein metabolic processGO:00322691060.019
cellular response to nitrogen compoundGO:19016992100.019
purine ribonucleotide catabolic processGO:00091541360.019
tube developmentGO:0035295890.019
positive regulation of cell communicationGO:00106472710.019
nucleoside phosphate metabolic processGO:00067532830.019
chemical homeostasisGO:00488782920.019
positive regulation of rna biosynthetic processGO:19026801970.019
oxidation reduction processGO:00551143040.019
nucleoside catabolic processGO:00091641260.019
protein complex assemblyGO:00064612630.019
locomotionGO:00400112370.019
negative regulation of response to stimulusGO:00485851550.019
positive regulation of response to stimulusGO:00485842850.018
positive regulation of gene expressionGO:00106282440.018
negative regulation of biosynthetic processGO:00098901680.018
positive regulation of catalytic activityGO:00430851840.018
regenerationGO:00310991630.018
macromolecular complex subunit organizationGO:00439333390.018
negative regulation of signalingGO:00230571570.018
negative regulation of cellular component organizationGO:0051129830.018
purine nucleoside catabolic processGO:00061521240.018
ras protein signal transductionGO:0007265290.018
nucleotide catabolic processGO:00091661390.018
positive regulation of phosphorylationGO:00423271770.018
negative regulation of cell proliferationGO:00082851190.018
regulation of hydrolase activityGO:00513361430.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
response to woundingGO:00096112540.018
positive regulation of cellular biosynthetic processGO:00313282950.018
negative regulation of nervous system developmentGO:0051961790.018
proteolysisGO:00065081750.017
heart morphogenesisGO:000300730.017
homeostatic processGO:00425923310.017
regulation of cellular localizationGO:00603412630.017
response to carbohydrateGO:00097431830.017
regulation of catalytic activityGO:00507903040.017
regulation of secretionGO:00510462240.017
cellular response to hormone stimulusGO:00328702470.017
regulation of cell morphogenesis involved in differentiationGO:0010769720.017
gonad developmentGO:00084061040.017
response to estrogenGO:00436272320.017
regulation of dendrite developmentGO:0050773590.016
secretion by cellGO:00329402480.016
regulation of hormone levelsGO:00108171870.016
regulation of catabolic processGO:00098941130.016
ion transmembrane transportGO:00342203650.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
negative regulation of developmental processGO:00510931250.016
cellular macromolecule localizationGO:00707271220.016
anion transportGO:00068201780.016
agingGO:00075682410.016
multicellular organism reproductionGO:00325042330.016
peptidyl tyrosine phosphorylationGO:0018108720.016
multicellular organismal reproductive processGO:00486092330.016
ribonucleoside catabolic processGO:00424541260.016
cellular nitrogen compound catabolic processGO:00442701630.016
single organism intracellular transportGO:19025821660.016
cytoplasmic transportGO:00164821150.016
reproductionGO:00000032450.016
purine nucleoside metabolic processGO:00422781690.016
negative regulation of macromolecule biosynthetic processGO:00105581480.015
intracellular transportGO:00469071850.015
regulation of cell morphogenesisGO:0022604770.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
positive regulation of protein metabolic processGO:00512471780.015
response to glucoseGO:00097491360.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
regulation of secretion by cellGO:19035302080.015
positive regulation of cell proliferationGO:00082842490.015
positive regulation of protein phosphorylationGO:00019341350.015
negative regulation of gene expressionGO:00106291990.015
nucleoside triphosphate metabolic processGO:00091411440.015
protein localizationGO:00081041910.015
growthGO:00400071650.015
response to nutrientGO:00075842480.015
anterior posterior pattern specificationGO:000995210.015
enzyme linked receptor protein signaling pathwayGO:00071671160.015
cellular protein localizationGO:00346131220.015
regulation of mesenchymal cell proliferationGO:001046440.015
blood circulationGO:00080151830.015
reproductive processGO:00224143720.015
negative regulation of protein metabolic processGO:00512481140.015
protein complex biogenesisGO:00702712630.015
organophosphate catabolic processGO:00464341480.015
regulation of mapk cascadeGO:00434081160.015
reproductive structure developmentGO:00486081280.015
negative regulation of cell differentiationGO:0045596990.015
ribonucleoside triphosphate metabolic processGO:00091991410.014
membrane organizationGO:0061024940.014
response to hexoseGO:00097461440.014
regulation of kinase activityGO:00435491170.014
actin filament based processGO:0030029860.014
positive regulation of cellular protein metabolic processGO:00322701670.014
action potentialGO:0001508540.014
response to monosaccharideGO:00342841590.014
female sex differentiationGO:0046660590.014
peptidyl amino acid modificationGO:00181931260.014
cellular response to peptideGO:19016531330.014
circulatory system developmentGO:00723591340.014
transmission of nerve impulseGO:0019226420.014
mapk cascadeGO:00001651400.014
cytoskeleton organizationGO:00070101110.014
establishment of tissue polarityGO:000716420.014
response to oxidative stressGO:00069791860.014
positive regulation of rna metabolic processGO:00512542030.014
neurological system processGO:00508772190.014
single organism membrane organizationGO:0044802740.014
dendrite developmentGO:0016358720.014
negative regulation of cell developmentGO:0010721820.014
cell communication involved in cardiac conductionGO:008606520.014
circulatory system processGO:00030131830.014
macromolecular complex assemblyGO:00650032730.014
regulation of cell growthGO:0001558850.014
response to insulinGO:00328681330.014
limb morphogenesisGO:003510840.013
response to other organismGO:00517072200.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
positive regulation of protein modification processGO:00314011420.013
metal ion transportGO:00300012890.013
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.013
organonitrogen compound biosynthetic processGO:19015661670.013
synaptic growth at neuromuscular junctionGO:005112410.013
negative regulation of osteoblast differentiationGO:004566820.013
sex differentiationGO:00075481130.013
regulation of anatomical structure sizeGO:00900661350.013
response to ketoneGO:19016541820.013
calcium ion homeostasisGO:00550741620.013
regulation of synaptic transmissionGO:00508041410.013
purine containing compound catabolic processGO:00725231380.013
response to estradiolGO:00323551640.013
regulation of establishment of planar polarityGO:009017520.013
cellular response to peptide hormone stimulusGO:00713751200.013
positive regulation of mapk cascadeGO:0043410920.013
axonogenesisGO:0007409710.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
negative regulation of catalytic activityGO:00430861030.013
neuron deathGO:00709971270.013
metal ion homeostasisGO:00550651860.013
peptidyl tyrosine modificationGO:0018212720.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
cell cycleGO:00070491010.013
regulation of axonogenesisGO:0050770370.012
purine nucleotide catabolic processGO:00061951360.012
negative regulation of cellular biosynthetic processGO:00313271610.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
cardiovascular system developmentGO:00723581340.012
regulation of nucleotide metabolic processGO:00061401170.012
neuronal action potentialGO:0019228350.012
chromosome segregationGO:000705920.012
cellular response to stressGO:00335542690.012
cellular chemical homeostasisGO:00550822470.012
developmental process involved in reproductionGO:00030061590.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
chemotaxisGO:0006935660.012
eye morphogenesisGO:004859240.012
small molecule biosynthetic processGO:00442831240.012
response to vitaminGO:00332731310.012
positive regulation of transcription dna templatedGO:00458931970.012
forebrain developmentGO:0030900980.012
ossificationGO:0001503700.012
coenzyme metabolic processGO:0006732860.012
regulation of transferase activityGO:00513381230.012
neuron projection morphogenesisGO:00488121220.012
establishment of protein localizationGO:00451841410.012
development of primary sexual characteristicsGO:00451371070.012
negative regulation of rna biosynthetic processGO:19026791180.012
regulation of g0 to g1 transitionGO:007031630.012
carboxylic acid biosynthetic processGO:0046394830.012
response to corticosteroidGO:00319602350.011
anatomical structure formation involved in morphogenesisGO:0048646830.011
negative regulation of phosphorus metabolic processGO:0010563800.011
axis specificationGO:000979840.011
response to metal ionGO:00100382530.011
organic hydroxy compound metabolic processGO:19016151150.011
carbohydrate derivative biosynthetic processGO:19011371240.011
negative regulation of phosphate metabolic processGO:0045936800.011
reproductive system developmentGO:00614581280.011
lipid biosynthetic processGO:00086101280.011
regulation of nucleotide catabolic processGO:0030811650.011
regulation of response to stressGO:00801341260.011
hormone secretionGO:00468791150.011
energy derivation by oxidation of organic compoundsGO:0015980460.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
morphogenesis of a polarized epitheliumGO:000173810.011
nucleoside triphosphate catabolic processGO:00091431230.011
ion homeostasisGO:00508012120.011
monovalent inorganic cation transportGO:00156721720.011
ribonucleotide catabolic processGO:00092611360.011
organ morphogenesisGO:0009887750.011
negative regulation of neurogenesisGO:0050768780.011
cellular homeostasisGO:00197252520.011
multicellular organism growthGO:003526410.011
signal transduction by phosphorylationGO:00230141440.011
single organism cellular localizationGO:19025801020.011
regulation of response to external stimulusGO:00321011060.011
wound healingGO:00420601220.011
monocarboxylic acid metabolic processGO:00327871520.011
cellular cation homeostasisGO:00300031800.011
developmental growthGO:00485891000.011
divalent inorganic cation homeostasisGO:00725071650.011
response to external biotic stimulusGO:00432072210.011
positive regulation of mesenchymal cell proliferationGO:000205340.011
actin cytoskeleton organizationGO:0030036730.011
regulation of gtpase activityGO:0043087570.011
regulation of purine nucleotide metabolic processGO:19005421150.011
cellular response to lipidGO:00713962010.011
response to biotic stimulusGO:00096072260.010
rhythmic processGO:00485111560.010
morphogenesis of embryonic epitheliumGO:001633130.010
carbohydrate metabolic processGO:00059751300.010
sexual reproductionGO:00199531480.010
gland developmentGO:00487321550.010
hair cycleGO:004263330.010
embryonic skeletal system developmentGO:004870630.010
reactive oxygen species metabolic processGO:0072593370.010
regulation of growthGO:00400081050.010
gamete generationGO:00072761240.010
mechanoreceptor differentiationGO:004249020.010
organic acid transportGO:00158491160.010
negative regulation of programmed cell deathGO:00430691830.010
bmp signaling pathwayGO:003050940.010
negative regulation of cell deathGO:00605482290.010
appendage morphogenesisGO:003510740.010
response to bacteriumGO:00096172000.010
regulation of cell migrationGO:00303341280.010
regulation of purine nucleotide catabolic processGO:0033121650.010
amide transportGO:00428861050.010
negative regulation of rna metabolic processGO:00512531230.010
erk1 and erk2 cascadeGO:0070371480.010
non canonical wnt signaling pathwayGO:003556730.010
rho protein signal transductionGO:0007266110.010
divalent inorganic cation transportGO:00725111340.010
cellular response to nutrient levelsGO:0031669600.010
negative regulation of apoptotic processGO:00430661810.010

Plekhg3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.034
disease of anatomical entityDOID:700.034
sensory system diseaseDOID:005015500.018
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
organ system cancerDOID:005068600.016
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.013
gastrointestinal system cancerDOID:311900.012