| positive regulation of intracellular signal transduction | GO:1902533 | 138 | 0.189 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.167 | |
| rna metabolic process | GO:0016070 | 406 | 0.159 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.153 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.105 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.102 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.095 | |
| transcription dna templated | GO:0006351 | 377 | 0.094 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.091 | |
| positive regulation of signaling | GO:0023056 | 270 | 0.091 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.071 | |
| cellular component assembly | GO:0022607 | 360 | 0.070 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.064 | |
| protein phosphorylation | GO:0006468 | 345 | 0.063 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.060 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.060 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.059 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.056 | |
| lipid metabolic process | GO:0006629 | 283 | 0.056 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.056 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.055 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.052 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.050 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.048 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.048 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.047 | |
| reproduction | GO:0000003 | 245 | 0.045 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.045 | |
| amine metabolic process | GO:0009308 | 38 | 0.043 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.042 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.042 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.042 | |
| positive regulation of protein phosphorylation | GO:0001934 | 135 | 0.042 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.040 | |
| regulation of molecular function | GO:0065009 | 398 | 0.040 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.038 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.038 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.038 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.037 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.037 | |
| negative regulation of tyrosine phosphorylation of stat5 protein | GO:0042524 | 1 | 0.037 | |
| programmed cell death | GO:0012501 | 392 | 0.037 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.036 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.035 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.034 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.034 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.034 | Fly |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.034 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.033 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.033 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.032 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.032 | |
| secretion | GO:0046903 | 307 | 0.032 | |
| cellular protein localization | GO:0034613 | 122 | 0.031 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.031 | |
| neuron apoptotic process | GO:0051402 | 88 | 0.030 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.029 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.029 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.029 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.029 | |
| cell projection organization | GO:0030030 | 302 | 0.029 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.028 | Mouse |
| regulation of catalytic activity | GO:0050790 | 304 | 0.028 | |
| single organism reproductive process | GO:0044702 | 297 | 0.028 | |
| defense response | GO:0006952 | 194 | 0.028 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.028 | |
| reproductive process | GO:0022414 | 372 | 0.028 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.028 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.027 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.027 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.027 | |
| muscle structure development | GO:0061061 | 87 | 0.027 | |
| protein oligomerization | GO:0051259 | 191 | 0.026 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.026 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.026 | |
| regulation of cellular component biogenesis | GO:0044087 | 86 | 0.026 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.026 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.026 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.026 | |
| organelle organization | GO:0006996 | 266 | 0.026 | |
| apoptotic process | GO:0006915 | 381 | 0.026 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.026 | |
| cellular response to stress | GO:0033554 | 269 | 0.025 | |
| positive regulation of protein modification process | GO:0031401 | 142 | 0.025 | |
| positive regulation of transferase activity | GO:0051347 | 81 | 0.025 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.025 | |
| cellular catabolic process | GO:0044248 | 295 | 0.025 | |
| catabolic process | GO:0009056 | 351 | 0.024 | Mouse |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.024 | |
| anterior posterior pattern specification | GO:0009952 | 1 | 0.024 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.024 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.024 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.023 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.023 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.023 | |
| intracellular protein transport | GO:0006886 | 79 | 0.023 | |
| behavior | GO:0007610 | 205 | 0.023 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 167 | 0.022 | |
| neuron projection development | GO:0031175 | 273 | 0.022 | |
| response to glucose | GO:0009749 | 136 | 0.022 | |
| protein complex assembly | GO:0006461 | 263 | 0.022 | |
| regulation of cellular catabolic process | GO:0031329 | 101 | 0.022 | |
| regulation of protein kinase activity | GO:0045859 | 105 | 0.021 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.021 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.021 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.021 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.021 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.021 | Mouse |
| regulation of apoptotic process | GO:0042981 | 335 | 0.021 | |
| negative regulation of activation of jak2 kinase activity | GO:1902569 | 1 | 0.021 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.021 | |
| response to sorbitol | GO:0072708 | 4 | 0.020 | |
| response to ethanol | GO:0045471 | 162 | 0.020 | |
| chromosome segregation | GO:0007059 | 2 | 0.020 | |
| neuron death | GO:0070997 | 127 | 0.020 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 1 | 0.020 | |
| macromolecule localization | GO:0033036 | 252 | 0.020 | Fly |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.020 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.020 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.019 | |
| locomotion | GO:0040011 | 237 | 0.019 | |
| anion transport | GO:0006820 | 178 | 0.019 | |
| regulation of cell development | GO:0060284 | 263 | 0.019 | |
| positive regulation of catabolic process | GO:0009896 | 78 | 0.019 | Mouse |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.019 | |
| intracellular transport | GO:0046907 | 185 | 0.019 | Fly |
| cytoskeleton organization | GO:0007010 | 111 | 0.019 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.019 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.018 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.018 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.018 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.018 | |
| response to heat | GO:0009408 | 60 | 0.018 | |
| response to nutrient levels | GO:0031667 | 370 | 0.018 | |
| positive regulation of kinase activity | GO:0033674 | 77 | 0.018 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.017 | |
| positive regulation of cellular catabolic process | GO:0031331 | 71 | 0.017 | |
| aromatic compound catabolic process | GO:0019439 | 168 | 0.017 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.017 | |
| lipid storage | GO:0019915 | 1 | 0.017 | |
| negative regulation of developmental process | GO:0051093 | 125 | 0.017 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.017 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.017 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.017 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.016 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.016 | |
| central nervous system development | GO:0007417 | 311 | 0.016 | |
| muscle system process | GO:0003012 | 115 | 0.016 | |
| nucleotide catabolic process | GO:0009166 | 139 | 0.016 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.016 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.016 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.015 | |
| activation of protein kinase activity | GO:0032147 | 47 | 0.015 | |
| protein localization | GO:0008104 | 191 | 0.015 | Fly |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.015 | |
| positive regulation of mitochondrion organization | GO:0010822 | 4 | 0.015 | |
| single organism cellular localization | GO:1902580 | 102 | 0.015 | |
| asymmetric protein localization | GO:0008105 | 2 | 0.015 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.015 | |
| cell cycle | GO:0007049 | 101 | 0.015 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.015 | |
| regulation of cell projection organization | GO:0031344 | 175 | 0.015 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.015 | |
| lipid biosynthetic process | GO:0008610 | 128 | 0.015 | |
| regulation of activation of janus kinase activity | GO:0010533 | 1 | 0.015 | |
| peptide biosynthetic process | GO:0043043 | 3 | 0.014 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.014 | |
| lipid localization | GO:0010876 | 62 | 0.014 | |
| gamete generation | GO:0007276 | 124 | 0.014 | |
| response to cytokine | GO:0034097 | 215 | 0.014 | |
| brain development | GO:0007420 | 247 | 0.014 | |
| positive regulation of gluconeogenesis | GO:0045722 | 3 | 0.014 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.014 | |
| regulation of map kinase activity | GO:0043405 | 53 | 0.013 | |
| heart morphogenesis | GO:0003007 | 3 | 0.013 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.013 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.013 | |
| actin filament based process | GO:0030029 | 86 | 0.013 | |
| protein localization to organelle | GO:0033365 | 57 | 0.013 | |
| sexual reproduction | GO:0019953 | 148 | 0.013 | |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.013 | |
| positive regulation of nervous system development | GO:0051962 | 178 | 0.013 | |
| response to metal ion | GO:0010038 | 253 | 0.013 | |
| homeostatic process | GO:0042592 | 331 | 0.013 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 106 | 0.013 | |
| aging | GO:0007568 | 241 | 0.013 | |
| cell motility | GO:0048870 | 202 | 0.013 | |
| jak stat cascade | GO:0007259 | 26 | 0.013 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 148 | 0.013 | |
| negative regulation of protein import into nucleus translocation | GO:0033159 | 1 | 0.013 | |
| cardiac chamber development | GO:0003205 | 1 | 0.013 | |
| neurological system process | GO:0050877 | 219 | 0.013 | |
| single organism catabolic process | GO:0044712 | 283 | 0.013 | |
| olfactory behavior | GO:0042048 | 2 | 0.012 | |
| regulation of growth | GO:0040008 | 105 | 0.012 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.012 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.012 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.012 | |
| spindle organization | GO:0007051 | 2 | 0.012 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.012 | |
| embryonic pattern specification | GO:0009880 | 1 | 0.012 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.012 | |
| response to ketone | GO:1901654 | 182 | 0.012 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.012 | |
| establishment of tissue polarity | GO:0007164 | 2 | 0.012 | |
| chemical homeostasis | GO:0048878 | 292 | 0.012 | |
| rho protein signal transduction | GO:0007266 | 11 | 0.012 | |
| response to monosaccharide | GO:0034284 | 159 | 0.012 | |
| response to wounding | GO:0009611 | 254 | 0.012 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.012 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 48 | 0.012 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 144 | 0.012 | |
| mapk cascade | GO:0000165 | 140 | 0.012 | |
| regulation of neuron apoptotic process | GO:0043523 | 83 | 0.012 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.012 | |
| peptidyl amino acid modification | GO:0018193 | 126 | 0.012 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.012 | |
| glial cell differentiation | GO:0010001 | 65 | 0.012 | |
| intracellular receptor signaling pathway | GO:0030522 | 35 | 0.011 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.011 | |
| chemosensory behavior | GO:0007635 | 2 | 0.011 | |
| activation of jak2 kinase activity | GO:0042977 | 2 | 0.011 | |
| ribonucleotide catabolic process | GO:0009261 | 136 | 0.011 | |
| response to radiation | GO:0009314 | 137 | 0.011 | |
| actin cytoskeleton organization | GO:0030036 | 73 | 0.011 | |
| head development | GO:0060322 | 247 | 0.011 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.011 | |
| muscle tissue development | GO:0060537 | 58 | 0.011 | |
| peptide hormone secretion | GO:0030072 | 84 | 0.011 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.011 | |
| response to carbohydrate | GO:0009743 | 183 | 0.011 | |
| negative regulation of molecular function | GO:0044092 | 133 | 0.011 | |
| single organism organelle organization | GO:1902589 | 180 | 0.011 | |
| muscle cell differentiation | GO:0042692 | 52 | 0.011 | |
| single organism carbohydrate metabolic process | GO:0044723 | 118 | 0.011 | |
| inflammatory response | GO:0006954 | 150 | 0.011 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.011 | Mouse |
| organic hydroxy compound metabolic process | GO:1901615 | 115 | 0.011 | |
| regulation of neuron death | GO:1901214 | 115 | 0.011 | |
| positive regulation of protein kinase activity | GO:0045860 | 73 | 0.011 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.011 | |
| neuron development | GO:0048666 | 286 | 0.010 | |
| negative regulation of nervous system development | GO:0051961 | 79 | 0.010 | |
| axis specification | GO:0009798 | 4 | 0.010 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 4 | 0.010 | |
| regulation of kinase activity | GO:0043549 | 117 | 0.010 | |
| single organism behavior | GO:0044708 | 130 | 0.010 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.010 | |
| neuron differentiation | GO:0030182 | 368 | 0.010 | |
| neuromuscular synaptic transmission | GO:0007274 | 2 | 0.010 | |
| carbohydrate homeostasis | GO:0033500 | 75 | 0.010 | |
| single organism membrane organization | GO:0044802 | 74 | 0.010 | |
| action potential | GO:0001508 | 54 | 0.010 | |