Rattus norvegicus

50 known processes

Mkl1

megakaryoblastic leukemia (translocation) 1

(Aliases: Mrtf-a)

Mkl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna biosynthetic processGO:00327743800.156
regulation of nucleic acid templated transcriptionGO:19035063800.122
rna metabolic processGO:00160704060.114
regulation of rna metabolic processGO:00512523910.113
regulation of rna biosynthetic processGO:20011413810.108
transcription dna templatedGO:00063513770.105
positive regulation of multicellular organismal processGO:00512403870.102
nucleic acid templated transcriptionGO:00976593790.093
response to extracellular stimulusGO:00099913800.093
regulation of multicellular organismal developmentGO:20000263760.092
anatomical structure morphogenesisGO:00096532980.091
protein complex subunit organizationGO:00718223020.089
positive regulation of nucleobase containing compound metabolic processGO:00459353190.088
Human
positive regulation of rna biosynthetic processGO:19026801970.086
Human
cellular component assemblyGO:00226073600.085
cellular component biogenesisGO:00440853680.085
cell motilityGO:00488702020.075
regulation of molecular functionGO:00650093980.073
positive regulation of nitrogen compound metabolic processGO:00511733340.068
Human
regulation of signal transductionGO:00099663180.066
locomotionGO:00400112370.064
positive regulation of molecular functionGO:00440932300.064
programmed cell deathGO:00125013920.064
macromolecular complex subunit organizationGO:00439333390.063
cell morphogenesis involved in differentiationGO:00009041190.062
regulation of programmed cell deathGO:00430673410.062
positive regulation of developmental processGO:00510942830.061
regulation of transcription dna templatedGO:00063553740.061
response to oxygen levelsGO:00704822650.061
positive regulation of macromolecule biosynthetic processGO:00105572470.061
Human
cell projection morphogenesisGO:00488581230.059
cell morphogenesis involved in neuron differentiationGO:00486671060.058
response to nutrient levelsGO:00316673700.058
positive regulation of biosynthetic processGO:00098913190.057
Human
regulation of cell differentiationGO:00455953200.057
apoptotic processGO:00069153810.057
tissue developmentGO:00098882520.056
localization of cellGO:00516742020.056
positive regulation of transcription dna templatedGO:00458931970.056
Human
regulation of cellular component organizationGO:00511283680.054
cell part morphogenesisGO:00329901230.053
biological adhesionGO:00226101100.052
reproductive processGO:00224143720.052
cellular component movementGO:00069282480.052
neuron projection morphogenesisGO:00488121220.051
regulation of cell motilityGO:20001451310.049
cell morphogenesisGO:00009021420.049
regulation of cellular protein metabolic processGO:00322682670.047
positive regulation of cellular component organizationGO:00511302000.047
cellular component morphogenesisGO:00329891550.047
positive regulation of cell differentiationGO:00455972170.046
cellular response to oxygen containing compoundGO:19017013860.046
regulation of catalytic activityGO:00507903040.046
negative regulation of metabolic processGO:00098923310.045
regulation of apoptotic processGO:00429813350.045
regulation of cell proliferationGO:00421273590.045
positive regulation of nucleic acid templated transcriptionGO:19035081970.044
Human
regulation of nervous system developmentGO:00519602640.044
response to hypoxiaGO:00016662310.043
positive regulation of phosphate metabolic processGO:00459372620.043
negative regulation of cellular metabolic processGO:00313242810.043
cell projection organizationGO:00300303020.043
cell migrationGO:00164771970.042
protein phosphorylationGO:00064683450.042
catabolic processGO:00090563510.042
regulation of system processGO:00440572080.042
single organism organelle organizationGO:19025891800.042
mapk cascadeGO:00001651400.041
negative regulation of cell deathGO:00605482290.041
regulation of protein metabolic processGO:00512462890.041
neuron projection developmentGO:00311752730.040
regulation of cell developmentGO:00602842630.040
regulation of phosphate metabolic processGO:00192203490.040
positive regulation of phosphorus metabolic processGO:00105622620.039
response to acid chemicalGO:00011012220.039
positive regulation of cellular biosynthetic processGO:00313282950.039
Human
positive regulation of response to stimulusGO:00485842850.037
cellular response to stressGO:00335542690.037
single organism reproductive processGO:00447022970.037
regulation of transcription from rna polymerase ii promoterGO:00063572340.037
organelle organizationGO:00069962660.036
positive regulation of catalytic activityGO:00430851840.036
organic substance catabolic processGO:19015753160.036
regulation of locomotionGO:00400121480.036
nucleotide metabolic processGO:00091172790.036
negative regulation of multicellular organismal processGO:00512412030.035
purine ribonucleoside metabolic processGO:00461281680.035
single organism catabolic processGO:00447122830.034
central nervous system developmentGO:00074173110.034
response to decreased oxygen levelsGO:00362932370.034
regulation of intracellular signal transductionGO:19025312180.033
positive regulation of rna metabolic processGO:00512542030.033
Human
protein complex biogenesisGO:00702712630.033
regulation of cellular component movementGO:00512701500.033
regulation of phosphorus metabolic processGO:00511743490.033
positive regulation of cell proliferationGO:00082842490.033
positive regulation of cell communicationGO:00106472710.033
cell type specific apoptotic processGO:00972851340.032
neurological system processGO:00508772190.032
transcription from rna polymerase ii promoterGO:00063662520.032
intracellular signal transductionGO:00355563140.032
positive regulation of protein metabolic processGO:00512471780.032
protein complex assemblyGO:00064612630.032
organic acid metabolic processGO:00060822920.031
positive regulation of protein phosphorylationGO:00019341350.031
macromolecular complex assemblyGO:00650032730.031
organophosphate metabolic processGO:00196373700.031
positive regulation of programmed cell deathGO:00430681570.031
positive regulation of nervous system developmentGO:00519621780.031
oxoacid metabolic processGO:00434362900.030
neuron developmentGO:00486662860.030
axonogenesisGO:0007409710.030
regulation of cellular ketone metabolic processGO:0010565270.030
positive regulation of phosphorylationGO:00423271770.030
response to peptide hormoneGO:00434342780.030
negative regulation of apoptotic processGO:00430661810.030
nucleoside triphosphate metabolic processGO:00091411440.029
positive regulation of gene expressionGO:00106282440.029
Human
gastrulationGO:000736920.029
negative regulation of macromolecule biosynthetic processGO:00105581480.029
ribonucleotide metabolic processGO:00092592310.029
cellular response to endogenous stimulusGO:00714953770.028
neuron differentiationGO:00301823680.028
regulation of neurogenesisGO:00507672470.028
small gtpase mediated signal transductionGO:0007264360.028
cell adhesionGO:00071551100.028
cell growthGO:00160491040.028
regulation of hydrolase activityGO:00513361430.028
cellular nitrogen compound catabolic processGO:00442701630.028
ribonucleoside metabolic processGO:00091191740.028
head developmentGO:00603222470.028
enzyme linked receptor protein signaling pathwayGO:00071671160.028
purine ribonucleotide metabolic processGO:00091502270.028
regulation of cell projection organizationGO:00313441750.027
cellular catabolic processGO:00442482950.027
positive regulation of signalingGO:00230562700.027
regulation of cell migrationGO:00303341280.027
cellular ketone metabolic processGO:0042180510.027
regulation of cell adhesionGO:0030155520.027
single organism biosynthetic processGO:00447113420.027
heterocycle catabolic processGO:00467001670.027
purine ribonucleotide catabolic processGO:00091541360.026
positive regulation of cell developmentGO:00107201760.026
ras protein signal transductionGO:0007265290.026
behaviorGO:00076102050.026
positive regulation of neurogenesisGO:00507691650.026
regulation of phosphorylationGO:00423252480.026
cellular response to hormone stimulusGO:00328702470.026
purine nucleoside metabolic processGO:00422781690.026
organic cyclic compound catabolic processGO:19013611750.025
protein localizationGO:00081041910.025
negative regulation of rna metabolic processGO:00512531230.025
response to inorganic substanceGO:00100353770.025
negative regulation of macromolecule metabolic processGO:00106052600.025
purine ribonucleoside catabolic processGO:00461301240.024
negative regulation of nitrogen compound metabolic processGO:00511721610.024
organonitrogen compound catabolic processGO:19015651790.024
chemotaxisGO:0006935660.024
response to metal ionGO:00100382530.024
aromatic compound catabolic processGO:00194391680.024
positive regulation of locomotionGO:00400171020.023
salivary gland developmentGO:000743130.023
brain developmentGO:00074202470.023
metal ion transportGO:00300012890.023
regulation of anatomical structure sizeGO:00900661350.023
protein autophosphorylationGO:0046777660.023
nucleoside phosphate metabolic processGO:00067532830.023
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
Human
regulation of cell morphogenesis involved in differentiationGO:0010769720.023
response to nutrientGO:00075842480.023
regulation of protein modification processGO:00313991940.023
regulation of protein phosphorylationGO:00019321830.023
positive regulation of apoptotic processGO:00430651540.023
immune system processGO:00023762040.023
nucleobase containing small molecule metabolic processGO:00550863160.022
growthGO:00400071650.022
ribonucleotide catabolic processGO:00092611360.022
positive regulation of protein modification processGO:00314011420.022
regulation of cellular amine metabolic processGO:003323880.022
negative regulation of programmed cell deathGO:00430691830.022
nucleobase containing compound catabolic processGO:00346551520.022
ribonucleoside catabolic processGO:00424541260.022
negative regulation of rna biosynthetic processGO:19026791180.022
multi organism reproductive processGO:00447032620.022
nucleoside triphosphate catabolic processGO:00091431230.022
synaptic growth at neuromuscular junctionGO:005112410.022
response to corticosteroidGO:00319602350.022
ribose phosphate metabolic processGO:00196932350.022
cytoskeleton organizationGO:00070101110.022
negative regulation of growthGO:0045926370.021
regulation of neuron differentiationGO:00456642080.021
positive regulation of cell motilityGO:2000147970.021
ribonucleoside triphosphate catabolic processGO:00092031220.021
regulation of kinase activityGO:00435491170.021
carbohydrate metabolic processGO:00059751300.021
regulation of protein kinase activityGO:00458591050.021
heart morphogenesisGO:000300730.021
response to cytokineGO:00340972150.021
response to carbohydrateGO:00097431830.021
glycosyl compound metabolic processGO:19016571820.021
positive regulation of transportGO:00510502450.021
carboxylic acid metabolic processGO:00197522890.020
lipid metabolic processGO:00066292830.020
nucleotide catabolic processGO:00091661390.020
regulation of growthGO:00400081050.020
agingGO:00075682410.020
regulation of cell growthGO:0001558850.020
negative regulation of cell communicationGO:00106481580.020
sexual reproductionGO:00199531480.020
positive regulation of cellular component movementGO:00512721020.020
regulation of cellular amino acid metabolic processGO:000652120.020
positive regulation of cellular protein metabolic processGO:00322701670.020
ribonucleoside triphosphate metabolic processGO:00091991410.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
learning or memoryGO:0007611900.020
response to peptideGO:19016522920.020
response to woundingGO:00096112540.020
cellular response to peptide hormone stimulusGO:00713751200.020
regulation of transferase activityGO:00513381230.020
positive regulation of intracellular signal transductionGO:19025331380.020
synapse organizationGO:0050808460.019
cellular amine metabolic processGO:0044106380.019
cellular response to peptideGO:19016531330.019
purine nucleoside catabolic processGO:00061521240.019
homeostatic processGO:00425923310.019
macromolecule localizationGO:00330362520.019
negative regulation of transcription dna templatedGO:00458921160.019
cardiovascular system developmentGO:00723581340.019
vesicle mediated transportGO:00161921810.019
actin filament based processGO:0030029860.019
epithelial cell differentiationGO:0030855710.019
negative regulation of gene expressionGO:00106291990.019
axon developmentGO:0061564960.019
single organism behaviorGO:00447081300.019
endocytosisGO:0006897840.019
cellular response to extracellular stimulusGO:0031668730.019
purine nucleotide catabolic processGO:00061951360.019
regulation of canonical wnt signaling pathwayGO:006082840.019
negative regulation of cellular component organizationGO:0051129830.019
taxisGO:0042330670.019
purine ribonucleoside triphosphate catabolic processGO:00092071220.019
proteolysisGO:00065081750.018
reproductionGO:00000032450.018
single organism cellular localizationGO:19025801020.018
positive regulation of mapk cascadeGO:0043410920.018
purine nucleotide metabolic processGO:00061632290.018
regulation of neuron apoptotic processGO:0043523830.018
carbohydrate derivative catabolic processGO:19011361470.018
regulation of neuron projection developmentGO:00109751610.018
regulation of cellular component biogenesisGO:0044087860.018
actin cytoskeleton organizationGO:0030036730.018
ameboidal type cell migrationGO:0001667260.018
nucleoside phosphate catabolic processGO:19012921400.018
positive regulation of cell deathGO:00109421840.018
positive regulation of signal transductionGO:00099671750.018
regulation of anatomical structure morphogenesisGO:00226031410.017
ion transmembrane transportGO:00342203650.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
glycosyl compound catabolic processGO:19016581260.017
nucleoside catabolic processGO:00091641260.017
sex differentiationGO:00075481130.017
cellular response to lipidGO:00713962010.017
forebrain developmentGO:0030900980.017
response to monosaccharideGO:00342841590.017
nucleoside metabolic processGO:00091161790.017
developmental process involved in reproductionGO:00030061590.017
formation of primary germ layerGO:000170410.017
reactive oxygen species metabolic processGO:0072593370.017
signal transduction by phosphorylationGO:00230141440.017
single organism cell adhesionGO:0098602460.017
negative regulation of biosynthetic processGO:00098901680.017
cation transportGO:00068123820.017
transmembrane transportGO:00550854120.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
dna metabolic processGO:0006259960.017
response to oxidative stressGO:00069791860.017
positive regulation of kinase activityGO:0033674770.017
negative regulation of nervous system developmentGO:0051961790.017
single organism carbohydrate metabolic processGO:00447231180.017
neuron deathGO:00709971270.017
purine containing compound catabolic processGO:00725231380.017
embryonic pattern specificationGO:000988010.017
cellular response to external stimulusGO:00714961180.017
response to growth factorGO:00708481890.017
amine metabolic processGO:0009308380.017
organ morphogenesisGO:0009887750.016
multicellular organism reproductionGO:00325042330.016
positive regulation of neuron projection developmentGO:0010976990.016
wound healingGO:00420601220.016
cellular response to nitrogen compoundGO:19016992100.016
positive regulation of hydrolase activityGO:0051345860.016
cellular response to organonitrogen compoundGO:00714171970.016
dendrite developmentGO:0016358720.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
negative regulation of signalingGO:00230571570.016
protein oligomerizationGO:00512591910.016
cellular homeostasisGO:00197252520.016
reproductive structure developmentGO:00486081280.016
multicellular organismal reproductive processGO:00486092330.016
muscle system processGO:00030121150.015
organophosphate catabolic processGO:00464341480.015
cellular amino acid metabolic processGO:00065201070.015
gliogenesisGO:0042063930.015
regulation of reactive oxygen species metabolic processGO:2000377260.015
cellular response to growth factor stimulusGO:00713631620.015
development of primary sexual characteristicsGO:00451371070.015
secretionGO:00469033070.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
salivary gland morphogenesisGO:000743510.015
purine containing compound metabolic processGO:00725212530.015
carbohydrate derivative metabolic processGO:19011353460.015
eye morphogenesisGO:004859240.015
chemosensory behaviorGO:000763520.015
embryo developmentGO:0009790490.015
negative regulation of cellular biosynthetic processGO:00313271610.015
regulation of proteasomal protein catabolic processGO:006113640.014
gamete generationGO:00072761240.014
olfactory behaviorGO:004204820.014
appendage morphogenesisGO:003510740.014
positive regulation of map kinase activityGO:0043406460.014
anatomical structure formation involved in morphogenesisGO:0048646830.014
reproductive system developmentGO:00614581280.014
spindle organizationGO:000705120.014
regulation of cellular catabolic processGO:00313291010.014
regulation of mapk cascadeGO:00434081160.014
positive regulation of cellular amine metabolic processGO:003324030.014
lipid biosynthetic processGO:00086101280.014
regulation of catabolic processGO:00098941130.014
anion transportGO:00068201780.014
epithelium developmentGO:0060429960.014
regulation of membrane potentialGO:00423911100.014
neuron apoptotic processGO:0051402880.014
developmental growthGO:00485891000.013
single organism intracellular transportGO:19025821660.013
peptidyl amino acid modificationGO:00181931260.013
gonad developmentGO:00084061040.013
cell cell signalingGO:00072673350.013
negative regulation of cell proliferationGO:00082851190.013
regulation of cell cycleGO:0051726730.013
negative regulation of developmental processGO:00510931250.013
negative regulation of response to stimulusGO:00485851550.013
cellular chemical homeostasisGO:00550822470.013
gland developmentGO:00487321550.013
camera type eye developmentGO:0043010480.013
circulatory system developmentGO:00723591340.013
cell substrate adhesionGO:0031589290.013
chemical homeostasisGO:00488782920.013
regulation of muscle system processGO:0090257790.013
defense responseGO:00069521940.013
positive regulation of cell projection organizationGO:00313461110.013
cognitionGO:0050890920.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
neuron projection guidanceGO:0097485240.013
negative regulation of molecular functionGO:00440921330.013
cell junction organizationGO:0034330210.013
response to estrogenGO:00436272320.013
sensory organ developmentGO:0007423740.013
erythrocyte differentiationGO:003021810.013
positive regulation of nucleoside metabolic processGO:0045979550.013
memoryGO:0007613540.013
response to hexoseGO:00097461440.012
regulation of protein serine threonine kinase activityGO:0071900640.012
cellular response to organic cyclic compoundGO:00714072020.012
cytoplasmic transportGO:00164821150.012
gtp catabolic processGO:0006184710.012
regulation of neuron deathGO:19012141150.012
heart developmentGO:0007507720.012
cellular carbohydrate metabolic processGO:0044262720.012
axis specificationGO:000979840.012
cell cell junction organizationGO:0045216200.012
urogenital system developmentGO:0001655780.012
regulation of purine nucleotide metabolic processGO:19005421150.012
positive regulation of cellular component biogenesisGO:0044089550.012
ossificationGO:0001503700.012
negative regulation of signal transductionGO:0009968830.012
response to ketoneGO:19016541820.012
limb morphogenesisGO:003510840.012
nitrogen compound transportGO:00717052290.012
reactive oxygen species biosynthetic processGO:190340980.012
regulation of secretionGO:00510462240.012
regulation of nucleotide metabolic processGO:00061401170.012
blood circulationGO:00080151830.012
regulation of vesicle mediated transportGO:0060627810.012
regulation of establishment of protein localizationGO:0070201690.012
regulation of ion transportGO:00432692450.012
positive regulation of gtpase activityGO:0043547470.012
response to transition metal nanoparticleGO:19902671220.012
lens fiber cell differentiationGO:007030630.012
negative regulation of protein metabolic processGO:00512481140.012
divalent inorganic cation transportGO:00725111340.012
positive regulation of neuron differentiationGO:00456661260.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
response to glucoseGO:00097491360.011
response to biotic stimulusGO:00096072260.011
chromatin assembly or disassemblyGO:000633310.011
regulation of organelle organizationGO:0033043800.011
intracellular transportGO:00469071850.011
calcium ion transportGO:00068161310.011
dendrite morphogenesisGO:0048813430.011
positive regulation of protein kinase activityGO:0045860730.011
negative regulation of cell differentiationGO:0045596990.011
muscle structure developmentGO:0061061870.011
Human
negative regulation of cell developmentGO:0010721820.011
reactive nitrogen species metabolic processGO:200105710.011
positive regulation of cell adhesionGO:0045785300.011
motor neuron axon guidanceGO:000804510.011
response to reactive oxygen speciesGO:00003021200.011
chromatin organizationGO:0006325340.011
axon guidanceGO:0007411240.011
response to toxic substanceGO:00096361330.011
rho protein signal transductionGO:0007266110.011
establishment of protein localizationGO:00451841410.011
anterior posterior pattern specificationGO:000995210.010
cellular response to nutrient levelsGO:0031669600.010
positive regulation of immune system processGO:0002684900.010
cellular lipid metabolic processGO:00442552080.010
regulation of proteolysisGO:0030162660.010
muscle contractionGO:0006936880.010
negative regulation of catalytic activityGO:00430861030.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
regulation of calcium ion transportGO:0051924770.010
negative regulation of neurogenesisGO:0050768780.010
divalent metal ion transportGO:00708381320.010
regulation of hormone levelsGO:00108171870.010

Mkl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.028
muscular diseaseDOID:008000000.015
muscle tissue diseaseDOID:6600.014
myopathyDOID:42300.014
nervous system diseaseDOID:86300.013