Rattus norvegicus

131 known processes

Hdac4

histone deacetylase 4

Hdac4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal developmentGO:20000263760.148
Mouse
nucleic acid templated transcriptionGO:00976593790.122
Human Mouse Fly
rna metabolic processGO:00160704060.115
Human Mouse Fly
rna biosynthetic processGO:00327743800.109
Human Mouse Fly
anatomical structure morphogenesisGO:00096532980.105
positive regulation of nitrogen compound metabolic processGO:00511733340.094
Human Mouse
regulation of transcription dna templatedGO:00063553740.093
Human Mouse Fly
regulation of cellular component organizationGO:00511283680.087
positive regulation of rna metabolic processGO:00512542030.082
Human Mouse
regulation of nucleic acid templated transcriptionGO:19035063800.078
Human Mouse Fly
cell projection organizationGO:00300303020.078
behaviorGO:00076102050.072
Fly
positive regulation of multicellular organismal processGO:00512403870.071
cell part morphogenesisGO:00329901230.069
positive regulation of biosynthetic processGO:00098913190.067
reproductive processGO:00224143720.064
oxoacid metabolic processGO:00434362900.063
Mouse
regulation of rna biosynthetic processGO:20011413810.063
Human Mouse Fly
cell cell signalingGO:00072673350.063
synaptic growth at neuromuscular junctionGO:005112410.062
positive regulation of rna biosynthetic processGO:19026801970.061
Human Mouse
neuron projection developmentGO:00311752730.060
regulation of molecular functionGO:00650093980.060
Human
positive regulation of nucleic acid templated transcriptionGO:19035081970.058
Human Mouse
positive regulation of macromolecule biosynthetic processGO:00105572470.058
Human Mouse
regulation of signal transductionGO:00099663180.056
cell morphogenesisGO:00009021420.056
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
Human Mouse
neuron developmentGO:00486662860.054
carboxylic acid metabolic processGO:00197522890.054
Mouse
negative regulation of metabolic processGO:00098923310.053
Human Mouse
neuron differentiationGO:00301823680.051
Rat
locomotionGO:00400112370.051
cell morphogenesis involved in differentiationGO:00009041190.051
positive regulation of developmental processGO:00510942830.051
central nervous system developmentGO:00074173110.051
organic acid metabolic processGO:00060822920.049
Mouse
positive regulation of cellular biosynthetic processGO:00313282950.049
Human Mouse
cellular ketone metabolic processGO:0042180510.048
neuron projection morphogenesisGO:00488121220.048
single organism reproductive processGO:00447022970.047
regulation of rna metabolic processGO:00512523910.047
Human Mouse Fly
negative regulation of cellular metabolic processGO:00313242810.047
Human Mouse
cellular component morphogenesisGO:00329891550.047
negative regulation of macromolecule metabolic processGO:00106052600.046
Human Mouse
protein complex subunit organizationGO:00718223020.045
regulation of cell projection organizationGO:00313441750.045
cell morphogenesis involved in neuron differentiationGO:00486671060.045
transcription from rna polymerase ii promoterGO:00063662520.045
Human Mouse
positive regulation of cellular component organizationGO:00511302000.045
regulation of system processGO:00440572080.044
Mouse
regulation of nervous system developmentGO:00519602640.044
regulation of phosphate metabolic processGO:00192203490.043
cell migrationGO:00164771970.043
regulation of cell developmentGO:00602842630.043
Mouse
positive regulation of programmed cell deathGO:00430681570.043
regulation of neurogenesisGO:00507672470.042
positive regulation of cell communicationGO:00106472710.042
hormone transportGO:00099141210.041
macromolecular complex subunit organizationGO:00439333390.041
head developmentGO:00603222470.041
regulation of cell differentiationGO:00455953200.040
Human Mouse
cellular component movementGO:00069282480.039
dendrite developmentGO:0016358720.039
regulation of cell morphogenesisGO:0022604770.039
dendrite morphogenesisGO:0048813430.039
regulation of cellular amino acid metabolic processGO:000652120.039
signal releaseGO:00230611450.039
positive regulation of gene expressionGO:00106282440.039
Human Mouse
regulation of phosphorus metabolic processGO:00511743490.039
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.038
Human Mouse
tissue developmentGO:00098882520.038
Mouse
cellular component biogenesisGO:00440853680.038
protein complex biogenesisGO:00702712630.038
protein complex assemblyGO:00064612630.037
cellular amino acid metabolic processGO:00065201070.037
cell projection morphogenesisGO:00488581230.037
regulation of anatomical structure morphogenesisGO:00226031410.037
cellular response to endogenous stimulusGO:00714953770.036
regulation of secretion by cellGO:19035302080.036
positive regulation of signalingGO:00230562700.036
macromolecular complex assemblyGO:00650032730.035
negative regulation of gene expressionGO:00106291990.035
Human Mouse
regulation of cellular ketone metabolic processGO:0010565270.035
secretion by cellGO:00329402480.034
regulation of cellular amine metabolic processGO:003323880.034
secretionGO:00469033070.033
response to other organismGO:00517072200.033
Rat
positive regulation of molecular functionGO:00440932300.033
Human
cellular amine metabolic processGO:0044106380.033
developmental process involved in reproductionGO:00030061590.032
regulation of neuron differentiationGO:00456642080.032
regulation of synaptic growth at neuromuscular junctionGO:000858210.032
cellular response to oxygen containing compoundGO:19017013860.031
Rat
cellular component assemblyGO:00226073600.031
negative regulation of multicellular organismal processGO:00512412030.031
Mouse
transcription dna templatedGO:00063513770.031
Human Mouse Fly
intracellular signal transductionGO:00355563140.031
Mouse
positive regulation of transcription dna templatedGO:00458931970.030
Human Mouse
amine metabolic processGO:0009308380.030
carbohydrate derivative metabolic processGO:19011353460.030
regulation of intracellular signal transductionGO:19025312180.030
organic substance catabolic processGO:19015753160.029
Mouse
regulation of cellular localizationGO:00603412630.029
regulation of hormone levelsGO:00108171870.028
positive regulation of response to stimulusGO:00485842850.028
localization of cellGO:00516742020.028
negative regulation of cellular component organizationGO:0051129830.028
ribonucleoside triphosphate catabolic processGO:00092031220.028
cell motilityGO:00488702020.027
positive regulation of cell developmentGO:00107201760.027
gonad developmentGO:00084061040.026
response to extracellular stimulusGO:00099913800.026
multicellular organismal reproductive processGO:00486092330.026
positive regulation of catalytic activityGO:00430851840.026
organic cyclic compound catabolic processGO:19013611750.026
nucleoside phosphate metabolic processGO:00067532830.026
regulation of neuron projection developmentGO:00109751610.026
positive regulation of phosphorus metabolic processGO:00105622620.026
regulation of apoptotic processGO:00429813350.026
positive regulation of signal transductionGO:00099671750.025
programmed cell deathGO:00125013920.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
small gtpase mediated signal transductionGO:0007264360.025
nucleobase containing small molecule metabolic processGO:00550863160.025
multicellular organism reproductionGO:00325042330.025
regulation of protein metabolic processGO:00512462890.024
Human
reproductive structure developmentGO:00486081280.024
response to nutrient levelsGO:00316673700.024
muscle system processGO:00030121150.024
Mouse
response to woundingGO:00096112540.024
purine nucleotide metabolic processGO:00061632290.024
positive regulation of apoptotic processGO:00430651540.024
regulation of catalytic activityGO:00507903040.024
brain developmentGO:00074202470.024
cellular response to hormone stimulusGO:00328702470.024
positive regulation of phosphate metabolic processGO:00459372620.024
ras protein signal transductionGO:0007265290.024
vesicle mediated transportGO:00161921810.023
positive regulation of neurogenesisGO:00507691650.023
cellular response to stressGO:00335542690.023
single organism catabolic processGO:00447122830.023
Mouse
regulation of cellular protein metabolic processGO:00322682670.023
Human
cardiovascular system developmentGO:00723581340.023
macromolecule localizationGO:00330362520.023
protein phosphorylationGO:00064683450.022
regulation of hydrolase activityGO:00513361430.022
neurological system processGO:00508772190.022
Fly
apoptotic processGO:00069153810.022
cellular nitrogen compound catabolic processGO:00442701630.022
reproductionGO:00000032450.022
nucleotide metabolic processGO:00091172790.022
regulation of secretionGO:00510462240.022
negative regulation of cell communicationGO:00106481580.022
positive regulation of nervous system developmentGO:00519621780.022
purine containing compound metabolic processGO:00725212530.022
cation transportGO:00068123820.022
negative regulation of rna metabolic processGO:00512531230.022
Human Mouse
glycosyl compound metabolic processGO:19016571820.022
regulation of anatomical structure sizeGO:00900661350.021
positive regulation of cellular amine metabolic processGO:003324030.021
synaptic transmissionGO:00072682350.021
multi organism reproductive processGO:00447032620.021
cellular response to growth factor stimulusGO:00713631620.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
Human Mouse
purine ribonucleotide metabolic processGO:00091502270.021
ribonucleotide metabolic processGO:00092592310.021
purine containing compound catabolic processGO:00725231380.021
peptidyl amino acid modificationGO:00181931260.021
Human
purine ribonucleoside metabolic processGO:00461281680.021
ribose phosphate metabolic processGO:00196932350.020
forebrain developmentGO:0030900980.020
positive regulation of phosphorylationGO:00423271770.020
regulation of cell motilityGO:20001451310.020
axonogenesisGO:0007409710.020
purine nucleoside triphosphate metabolic processGO:00091441410.020
response to peptideGO:19016522920.020
regulation of synaptic plasticityGO:0048167700.020
nucleoside triphosphate metabolic processGO:00091411440.020
development of primary sexual characteristicsGO:00451371070.020
purine nucleoside catabolic processGO:00061521240.020
organonitrogen compound catabolic processGO:19015651790.020
transmembrane transportGO:00550854120.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.019
Human Mouse
homeostatic processGO:00425923310.019
regulation of protein modification processGO:00313991940.019
Human
metal ion transportGO:00300012890.019
sex differentiationGO:00075481130.019
negative regulation of response to stimulusGO:00485851550.019
negative regulation of rna biosynthetic processGO:19026791180.019
Human Mouse
regulation of locomotionGO:00400121480.019
hormone secretionGO:00468791150.019
response to growth factorGO:00708481890.019
cellular catabolic processGO:00442482950.019
Mouse
enzyme linked receptor protein signaling pathwayGO:00071671160.018
negative regulation of transportGO:00510511360.018
circulatory system developmentGO:00723591340.018
cell adhesionGO:00071551100.018
response to oxygen levelsGO:00704822650.018
cellular response to organonitrogen compoundGO:00714171970.018
regulation of cellular component movementGO:00512701500.018
protein oligomerizationGO:00512591910.018
negative regulation of transcription dna templatedGO:00458921160.018
Human Mouse
biological adhesionGO:00226101100.018
regulation of proteasomal protein catabolic processGO:006113640.018
epithelium developmentGO:0060429960.018
positive regulation of cell deathGO:00109421840.018
protein autophosphorylationGO:0046777660.017
growthGO:00400071650.017
cellular response to nitrogen compoundGO:19016992100.017
response to lipopolysaccharideGO:00324961910.017
Rat
nucleoside phosphate catabolic processGO:19012921400.017
regulation of dendrite developmentGO:0050773590.017
protein localizationGO:00081041910.017
divalent inorganic cation transportGO:00725111340.017
positive regulation of neuron differentiationGO:00456661260.017
response to metal ionGO:00100382530.017
regulation of transferase activityGO:00513381230.017
positive regulation of cell differentiationGO:00455972170.017
positive regulation of protein metabolic processGO:00512471780.017
Human
response to molecule of bacterial originGO:00022371940.017
Rat
regulation of protein kinase activityGO:00458591050.017
oxidation reduction processGO:00551143040.017
negative regulation of signalingGO:00230571570.017
response to external biotic stimulusGO:00432072210.017
Rat
cellular homeostasisGO:00197252520.017
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
Human Mouse
regulation of hormone secretionGO:00468831060.017
negative regulation of phosphate metabolic processGO:0045936800.016
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.016
Human Mouse
regulation of cell proliferationGO:00421273590.016
organophosphate metabolic processGO:00196373700.016
heterocycle catabolic processGO:00467001670.016
developmental growthGO:00485891000.016
embryonic pattern specificationGO:000988010.016
response to biotic stimulusGO:00096072260.016
Rat
regulation of programmed cell deathGO:00430673410.016
chemical homeostasisGO:00488782920.016
positive regulation of cellular protein metabolic processGO:00322701670.016
Human
regulation of cellular component biogenesisGO:0044087860.016
glycosyl compound catabolic processGO:19016581260.016
nucleotide catabolic processGO:00091661390.016
gastrulationGO:000736920.016
bmp signaling pathwayGO:003050940.016
response to glucoseGO:00097491360.016
chromosome segregationGO:000705920.015
response to hexoseGO:00097461440.015
taxisGO:0042330670.015
negative regulation of nervous system developmentGO:0051961790.015
aromatic compound catabolic processGO:00194391680.015
negative regulation of biosynthetic processGO:00098901680.015
Human Mouse
ribonucleoside metabolic processGO:00091191740.015
nucleoside triphosphate catabolic processGO:00091431230.015
appendage morphogenesisGO:003510740.015
nucleoside catabolic processGO:00091641260.015
nucleobase containing compound catabolic processGO:00346551520.015
gamete generationGO:00072761240.015
negative regulation of molecular functionGO:00440921330.015
Human
positive regulation of transportGO:00510502450.015
sexual reproductionGO:00199531480.015
positive regulation of neuron projection developmentGO:0010976990.015
reproductive system developmentGO:00614581280.015
catabolic processGO:00090563510.015
Mouse
purine nucleoside metabolic processGO:00422781690.015
nitrogen compound transportGO:00717052290.014
nucleoside metabolic processGO:00091161790.014
proteolysisGO:00065081750.014
single organism biosynthetic processGO:00447113420.014
regulation of catabolic processGO:00098941130.014
Mouse
actin filament based processGO:0030029860.014
organelle organizationGO:00069962660.014
response to decreased oxygen levelsGO:00362932370.014
urogenital system developmentGO:0001655780.014
mapk cascadeGO:00001651400.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
positive regulation of mapk cascadeGO:0043410920.014
cellular chemical homeostasisGO:00550822470.014
positive regulation of cell projection organizationGO:00313461110.014
response to glucocorticoidGO:00513842230.014
axon developmentGO:0061564960.014
motor neuron axon guidanceGO:000804510.014
negative regulation of cell proliferationGO:00082851190.014
Mouse
ribonucleoside triphosphate metabolic processGO:00091991410.014
response to acid chemicalGO:00011012220.014
response to hypoxiaGO:00016662310.014
response to inorganic substanceGO:00100353770.014
cell growthGO:00160491040.014
anterior posterior pattern specificationGO:000995210.014
positive regulation of protein modification processGO:00314011420.014
Human
response to carbohydrateGO:00097431830.013
response to ethanolGO:00454711620.013
limb morphogenesisGO:003510840.013
single organism behaviorGO:00447081300.013
Fly
cellular ion homeostasisGO:00068731840.013
embryonic appendage morphogenesisGO:003511340.013
regulation of protein phosphorylationGO:00019321830.013
mesoderm developmentGO:000749820.013
regulation of growthGO:00400081050.013
axis specificationGO:000979840.013
positive regulation of catabolic processGO:0009896780.013
positive regulation of protein phosphorylationGO:00019341350.013
response to monosaccharideGO:00342841590.013
ribonucleoside catabolic processGO:00424541260.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
Human Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051400.013
synapse assemblyGO:0007416290.013
regulation of phosphorylationGO:00423252480.013
regulation of organelle organizationGO:0033043800.013
agingGO:00075682410.013
dephosphorylationGO:0016311980.013
rhythmic processGO:00485111560.013
lipid metabolic processGO:00066292830.013
regulation of axonogenesisGO:0050770370.013
circulatory system processGO:00030131830.013
Mouse
response to nutrientGO:00075842480.013
ribonucleotide catabolic processGO:00092611360.013
salivary gland morphogenesisGO:000743510.012
negative regulation of neurogenesisGO:0050768780.012
cognitionGO:0050890920.012
Fly
olfactory behaviorGO:004204820.012
purine ribonucleotide catabolic processGO:00091541360.012
regulation of cell growthGO:0001558850.012
salivary gland developmentGO:000743130.012
multicellular organism growthGO:003526410.012
ion transmembrane transportGO:00342203650.012
rho protein signal transductionGO:0007266110.012
regulation of synaptic transmissionGO:00508041410.012
cellular protein localizationGO:00346131220.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.012
negative regulation of cell deathGO:00605482290.012
organonitrogen compound biosynthetic processGO:19015661670.012
regulation of purine nucleotide metabolic processGO:19005421150.012
cytoskeleton organizationGO:00070101110.012
regulation of response to stressGO:00801341260.012
regulation of cell migrationGO:00303341280.012
purine nucleotide catabolic processGO:00061951360.012
mitotic spindle organizationGO:000705220.012
response to cytokineGO:00340972150.012
regulation of vesicle mediated transportGO:0060627810.012
b cell differentiationGO:003018320.012
cell type specific apoptotic processGO:00972851340.012
ion homeostasisGO:00508012120.011
membrane organizationGO:0061024940.011
multi multicellular organism processGO:00447061380.011
carboxylic acid transportGO:00469421150.011
positive regulation of hydrolase activityGO:0051345860.011
carbohydrate derivative catabolic processGO:19011361470.011
amide transportGO:00428861050.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
Human Mouse
cellular response to organic cyclic compoundGO:00714072020.011
cellular response to peptideGO:19016531330.011
regulation of mapk cascadeGO:00434081160.011
embryo developmentGO:0009790490.011
negative regulation of secretionGO:0051048820.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
regulation of cellular catabolic processGO:00313291010.011
Mouse
male sex differentiationGO:0046661640.011
organophosphate catabolic processGO:00464341480.011
regulation of kinase activityGO:00435491170.011
regulation of nucleotide metabolic processGO:00061401170.011
non canonical wnt signaling pathwayGO:003556730.010
spindle organizationGO:000705120.010
negative regulation of programmed cell deathGO:00430691830.010
regulation of nucleoside metabolic processGO:0009118660.010
negative regulation of catalytic activityGO:00430861030.010
regulation of membrane potentialGO:00423911100.010
regulation of cell adhesionGO:0030155520.010
actin cytoskeleton organizationGO:0030036730.010
heart developmentGO:0007507720.010
male mating behaviorGO:006017930.010
cellular calcium ion homeostasisGO:00068741600.010
regulation of purine nucleotide catabolic processGO:0033121650.010
signal transduction by phosphorylationGO:00230141440.010
response to estradiolGO:00323551640.010
positive regulation of cell proliferationGO:00082842490.010
purine ribonucleoside catabolic processGO:00461301240.010
blood circulationGO:00080151830.010
Mouse
synapse organizationGO:0050808460.010
regulation of ion transportGO:00432692450.010

Hdac4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.019
disease of anatomical entityDOID:700.019
connective tissue diseaseDOID:6500.017
bone diseaseDOID:008000100.017
nervous system diseaseDOID:86300.014