Rattus norvegicus

38 known processes

Hdac6

histone deacetylase 6

Hdac6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.098
locomotionGO:00400112370.096
Human
regulation of multicellular organismal developmentGO:20000263760.087
rna biosynthetic processGO:00327743800.084
Fly
cellular component movementGO:00069282480.077
Human
rna metabolic processGO:00160704060.066
Fly
lipid metabolic processGO:00066292830.064
cell cell signalingGO:00072673350.063
Fly
anatomical structure morphogenesisGO:00096532980.062
secretion by cellGO:00329402480.059
Fly
intracellular signal transductionGO:00355563140.058
response to nutrient levelsGO:00316673700.057
Human
response to extracellular stimulusGO:00099913800.051
Human
carboxylic acid metabolic processGO:00197522890.050
localization of cellGO:00516742020.048
Human
organic acid metabolic processGO:00060822920.047
regulation of cellular component organizationGO:00511283680.047
Human
regulation of transcription dna templatedGO:00063553740.046
Fly
positive regulation of developmental processGO:00510942830.045
macromolecular complex subunit organizationGO:00439333390.045
Human Fly
neuron differentiationGO:00301823680.045
cellular catabolic processGO:00442482950.044
Human
cellular lipid metabolic processGO:00442552080.044
ion transmembrane transportGO:00342203650.044
tissue developmentGO:00098882520.043
response to peptideGO:19016522920.040
regulation of rna metabolic processGO:00512523910.038
Fly
positive regulation of multicellular organismal processGO:00512403870.038
Human
regulation of nervous system developmentGO:00519602640.037
cell motilityGO:00488702020.037
Human
synaptic growth at neuromuscular junctionGO:005112410.037
catabolic processGO:00090563510.037
Human
glycerolipid metabolic processGO:0046486670.037
regulation of programmed cell deathGO:00430673410.036
Human
macromolecule localizationGO:00330362520.036
Human
cellular component morphogenesisGO:00329891550.036
blood circulationGO:00080151830.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
Fly
regulation of cell proliferationGO:00421273590.034
nucleic acid templated transcriptionGO:00976593790.034
Fly
single organism catabolic processGO:00447122830.034
Human
secretionGO:00469033070.034
Fly
regulation of rna biosynthetic processGO:20011413810.033
Fly
neurological system processGO:00508772190.033
response to peptide hormoneGO:00434342780.033
response to oxygen levelsGO:00704822650.032
positive regulation of transportGO:00510502450.031
cation homeostasisGO:00550801950.031
organic anion transportGO:00157111320.031
transcription dna templatedGO:00063513770.031
Fly
anion transportGO:00068201780.031
synaptic transmissionGO:00072682350.031
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
single organism biosynthetic processGO:00447113420.030
dna metabolic processGO:0006259960.030
programmed cell deathGO:00125013920.029
Human
cation transportGO:00068123820.029
positive regulation of nervous system developmentGO:00519621780.029
regulation of synaptic growth at neuromuscular junctionGO:000858210.029
head developmentGO:00603222470.029
positive regulation of response to stimulusGO:00485842850.029
Human
regulation of anatomical structure morphogenesisGO:00226031410.029
regulation of secretionGO:00510462240.029
ras protein signal transductionGO:0007265290.028
cellular response to cytokine stimulusGO:00713451270.028
transmembrane transportGO:00550854120.028
cellular component biogenesisGO:00440853680.028
Human
response to nutrientGO:00075842480.028
chemical homeostasisGO:00488782920.027
circulatory system processGO:00030131830.027
positive regulation of nitrogen compound metabolic processGO:00511733340.027
protein oligomerizationGO:00512591910.026
transcription from rna polymerase ii promoterGO:00063662520.026
regulation of apoptotic processGO:00429813350.026
negative regulation of transportGO:00510511360.026
lipid modificationGO:0030258520.026
nitrogen compound transportGO:00717052290.026
cellular response to oxygen containing compoundGO:19017013860.025
Human
macromolecular complex assemblyGO:00650032730.025
Human
regulation of system processGO:00440572080.025
growthGO:00400071650.025
central nervous system developmentGO:00074173110.025
Rat
protein complex subunit organizationGO:00718223020.025
Human
organic substance catabolic processGO:19015753160.024
Human
regulation of cellular ketone metabolic processGO:0010565270.024
response to cytokineGO:00340972150.024
small gtpase mediated signal transductionGO:0007264360.024
cellular component assemblyGO:00226073600.024
Human
regulation of cell differentiationGO:00455953200.024
nucleotide metabolic processGO:00091172790.023
positive regulation of cell differentiationGO:00455972170.023
apoptotic processGO:00069153810.023
response to growth factorGO:00708481890.023
Human
g protein coupled receptor signaling pathwayGO:00071862420.023
vesicle mediated transportGO:00161921810.023
cellular response to endogenous stimulusGO:00714953770.023
cellular ion homeostasisGO:00068731840.023
organelle organizationGO:00069962660.023
Human Fly
response to acid chemicalGO:00011012220.023
establishment of protein localizationGO:00451841410.023
Human
amine metabolic processGO:0009308380.023
reproductive processGO:00224143720.023
cellular amino acid metabolic processGO:00065201070.022
monocarboxylic acid metabolic processGO:00327871520.022
positive regulation of biosynthetic processGO:00098913190.022
Human
cation transmembrane transportGO:00986552630.022
cellular amine metabolic processGO:0044106380.022
response to corticosteroidGO:00319602350.022
regulation of cellular component movementGO:00512701500.021
Human
metal ion homeostasisGO:00550651860.021
regulation of blood pressureGO:0008217830.021
organophosphate metabolic processGO:00196373700.021
cellular metal ion homeostasisGO:00068751720.021
ion homeostasisGO:00508012120.021
regulation of phosphate metabolic processGO:00192203490.021
inorganic ion transmembrane transportGO:00986602290.020
regulation of phosphorylationGO:00423252480.020
cellular chemical homeostasisGO:00550822470.020
regulation of neurogenesisGO:00507672470.020
nucleobase containing small molecule metabolic processGO:00550863160.020
homeostatic processGO:00425923310.020
developmental growthGO:00485891000.020
carbohydrate derivative metabolic processGO:19011353460.020
regulation of cellular localizationGO:00603412630.020
ribose phosphate metabolic processGO:00196932350.020
positive regulation of rna metabolic processGO:00512542030.019
cellular response to stressGO:00335542690.019
Human
regulation of phosphorus metabolic processGO:00511743490.019
brain developmentGO:00074202470.019
positive regulation of macromolecule biosynthetic processGO:00105572470.019
Human
divalent metal ion transportGO:00708381320.019
positive regulation of rna biosynthetic processGO:19026801970.019
response to decreased oxygen levelsGO:00362932370.019
multi organism reproductive processGO:00447032620.019
cell morphogenesis involved in differentiationGO:00009041190.019
regulation of cell developmentGO:00602842630.019
cardiovascular system developmentGO:00723581340.019
single organism intracellular transportGO:19025821660.019
Human
cellular homeostasisGO:00197252520.019
positive regulation of phosphorus metabolic processGO:00105622620.018
single organism cellular localizationGO:19025801020.018
multicellular organismal reproductive processGO:00486092330.018
regulation of secretion by cellGO:19035302080.018
positive regulation of cellular component movementGO:00512721020.018
Human
cell morphogenesisGO:00009021420.018
multicellular organism growthGO:003526410.018
cell migrationGO:00164771970.018
Human
cellular response to hormone stimulusGO:00328702470.018
regulation of ion transportGO:00432692450.018
organic acid transportGO:00158491160.017
vasculature developmentGO:0001944700.017
developmental process involved in reproductionGO:00030061590.017
protein complex assemblyGO:00064612630.017
Human
carboxylic acid transportGO:00469421150.017
neuron projection developmentGO:00311752730.017
negative regulation of response to stimulusGO:00485851550.017
regulation of cell projection organizationGO:00313441750.017
response to other organismGO:00517072200.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
regulation of neuron projection developmentGO:00109751610.017
positive regulation of cellular component organizationGO:00511302000.017
Human
negative regulation of metabolic processGO:00098923310.017
Human
carbohydrate metabolic processGO:00059751300.017
regulation of cellular amino acid metabolic processGO:000652120.017
endocytosisGO:0006897840.016
neuron developmentGO:00486662860.016
regulation of signal transductionGO:00099663180.016
Human
cell morphogenesis involved in neuron differentiationGO:00486671060.016
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
multicellular organism reproductionGO:00325042330.016
calcium ion homeostasisGO:00550741620.016
protein complex biogenesisGO:00702712630.016
Human
negative regulation of cell communicationGO:00106481580.016
positive regulation of transcription dna templatedGO:00458931970.016
regulation of synaptic transmissionGO:00508041410.016
negative regulation of signalingGO:00230571570.016
regulation of growthGO:00400081050.016
agingGO:00075682410.016
protein phosphorylationGO:00064683450.016
positive regulation of cellular biosynthetic processGO:00313282950.015
positive regulation of cell developmentGO:00107201760.015
response to hypoxiaGO:00016662310.015
purine containing compound metabolic processGO:00725212530.015
cellular cation homeostasisGO:00300031800.015
regulation of developmental growthGO:0048638450.015
inorganic cation transmembrane transportGO:00986622020.015
insulin like growth factor receptor signaling pathwayGO:004800930.015
nucleoside phosphate metabolic processGO:00067532830.015
axonogenesisGO:0007409710.015
response to estrogenGO:00436272320.015
neuron projection morphogenesisGO:00488121220.015
female sex differentiationGO:0046660590.015
organic hydroxy compound metabolic processGO:19016151150.015
positive regulation of molecular functionGO:00440932300.015
regulation of molecular functionGO:00650093980.015
Human
organonitrogen compound biosynthetic processGO:19015661670.015
cellular ketone metabolic processGO:0042180510.015
behaviorGO:00076102050.014
metal ion transportGO:00300012890.014
cellular response to lipidGO:00713962010.014
forebrain developmentGO:0030900980.014
regulation of cellular amine metabolic processGO:003323880.014
hexose metabolic processGO:0019318580.014
positive regulation of cellular amine metabolic processGO:003324030.014
defense responseGO:00069521940.014
cell projection organizationGO:00300303020.014
response to oxidative stressGO:00069791860.014
Human
regulation of response to stressGO:00801341260.014
Human
response to hexoseGO:00097461440.014
morphogenesis of a polarized epitheliumGO:000173810.014
reproductionGO:00000032450.014
positive regulation of cell migrationGO:0030335960.014
Human
regulation of hormone levelsGO:00108171870.014
divalent inorganic cation homeostasisGO:00725071650.014
monoamine transportGO:0015844430.014
regulation of cellular protein metabolic processGO:00322682670.014
Human
organophosphate biosynthetic processGO:00904071430.014
negative regulation of macromolecule metabolic processGO:00106052600.014
Human
negative regulation of programmed cell deathGO:00430691830.014
regulation of vesicle mediated transportGO:0060627810.014
regulation of neuron differentiationGO:00456642080.014
cell projection morphogenesisGO:00488581230.014
axon developmentGO:0061564960.014
positive regulation of cell proliferationGO:00082842490.013
eye morphogenesisGO:004859240.013
response to carbohydrateGO:00097431830.013
small molecule biosynthetic processGO:00442831240.013
spindle organizationGO:000705120.013
nucleotide biosynthetic processGO:0009165980.013
rhythmic processGO:00485111560.013
circulatory system developmentGO:00723591340.013
response to interleukin 1GO:0070555550.013
organic hydroxy compound transportGO:0015850770.013
regulation of intracellular signal transductionGO:19025312180.013
intracellular protein transportGO:0006886790.013
Human
regulation of catalytic activityGO:00507903040.013
negative regulation of innate immune responseGO:004582440.013
negative regulation of multicellular organismal processGO:00512412030.013
cellular response to growth factor stimulusGO:00713631620.013
response to inorganic substanceGO:00100353770.013
Human
single organism reproductive processGO:00447022970.013
purine nucleotide metabolic processGO:00061632290.013
protein dna complex disassemblyGO:003298610.013
neuron deathGO:00709971270.013
protein heterooligomerizationGO:0051291890.013
regulation of membrane potentialGO:00423911100.012
neural crest cell developmentGO:001403220.012
gland developmentGO:00487321550.012
response to ketoneGO:19016541820.012
regulation of neuron deathGO:19012141150.012
positive regulation of phosphorylationGO:00423271770.012
response to fatty acidGO:0070542650.012
negative regulation of cellular metabolic processGO:00313242810.012
Human
reproductive structure developmentGO:00486081280.012
blood vessel developmentGO:0001568690.012
positive regulation of phosphate metabolic processGO:00459372620.012
positive regulation of neurogenesisGO:00507691650.012
positive regulation of signalingGO:00230562700.012
Human
response to reactive oxygen speciesGO:00003021200.012
Human
regulation of transmembrane transportGO:00347621220.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
negative regulation of gene expressionGO:00106291990.012
Human
epithelium developmentGO:0060429960.012
chemotaxisGO:0006935660.012
positive regulation of signal transductionGO:00099671750.012
Human
inflammatory responseGO:00069541500.012
pigment biosynthetic processGO:004614840.012
positive regulation of secretionGO:00510471400.012
synapse organizationGO:0050808460.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
fatty acid metabolic processGO:0006631990.012
response to estradiolGO:00323551640.012
cellular response to organonitrogen compoundGO:00714171970.012
cerebral cortex cell migrationGO:002179540.012
ovulation cycleGO:0042698670.012
neural crest cell differentiationGO:001403320.012
ribose phosphate biosynthetic processGO:0046390870.012
reproductive system developmentGO:00614581280.011
phospholipid metabolic processGO:0006644610.011
acute inflammatory responseGO:0002526580.011
ribonucleotide metabolic processGO:00092592310.011
nucleoside phosphate biosynthetic processGO:19012931020.011
regulation of ion transmembrane transportGO:00347651210.011
cellular calcium ion homeostasisGO:00068741600.011
carbohydrate derivative biosynthetic processGO:19011371240.011
immune system processGO:00023762040.011
response to glucoseGO:00097491360.011
purine ribonucleotide metabolic processGO:00091502270.011
positive regulation of ion transportGO:0043270940.011
protein homooligomerizationGO:0051260910.011
cellular response to nitrogen compoundGO:19016992100.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
lipid localizationGO:0010876620.011
lipid transportGO:0006869610.011
axis specificationGO:000979840.011
cellular carbohydrate metabolic processGO:0044262720.011
signal releaseGO:00230611450.011
Fly
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
synaptic vesicle endocytosisGO:004848840.011
response to lipopolysaccharideGO:00324961910.011
alternative mrna splicing via spliceosomeGO:000038040.011
anterior posterior pattern specificationGO:000995210.011
response to toxic substanceGO:00096361330.011
Human
aromatic compound catabolic processGO:00194391680.010
response to insulinGO:00328681330.010
mapk cascadeGO:00001651400.010
muscle structure developmentGO:0061061870.010
regulation of locomotionGO:00400121480.010
Human
oxidation reduction processGO:00551143040.010
Fly
establishment of tissue polarityGO:000716420.010
negative regulation of protein metabolic processGO:00512481140.010
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
immune responseGO:00069551040.010
cellular macromolecule localizationGO:00707271220.010
Human
response to mechanical stimulusGO:00096121340.010
positive regulation of locomotionGO:00400171020.010
Human
neural crest cell migrationGO:000175510.010
response to ethanolGO:00454711620.010
calcium ion transportGO:00068161310.010
cytoplasmic transportGO:00164821150.010
negative regulation of cell deathGO:00605482290.010
positive regulation of neuron differentiationGO:00456661260.010

Hdac6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.042
disease of anatomical entityDOID:700.042
muscle tissue diseaseDOID:6600.020
musculoskeletal system diseaseDOID:1700.020
muscular diseaseDOID:008000000.020
central nervous system diseaseDOID:33100.017
myopathyDOID:42300.017
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
muscular dystrophyDOID:988400.013
cardiovascular system diseaseDOID:128700.010