Rattus norvegicus

46 known processes

H2afx

H2A histone family, member X

(Aliases: RGD1566119)

H2afx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.091
nucleic acid templated transcriptionGO:00976593790.088
negative regulation of gene expressionGO:00106291990.088
negative regulation of metabolic processGO:00098923310.079
negative regulation of macromolecule metabolic processGO:00106052600.078
negative regulation of nitrogen compound metabolic processGO:00511721610.070
negative regulation of cellular metabolic processGO:00313242810.070
negative regulation of cellular biosynthetic processGO:00313271610.063
organelle organizationGO:00069962660.060
negative regulation of biosynthetic processGO:00098901680.060
positive regulation of nucleobase containing compound metabolic processGO:00459353190.053
single organism organelle organizationGO:19025891800.051
negative regulation of nucleobase containing compound metabolic processGO:00459341530.049
positive regulation of nitrogen compound metabolic processGO:00511733340.049
regulation of nucleic acid templated transcriptionGO:19035063800.048
response to peptide hormoneGO:00434342780.048
rna biosynthetic processGO:00327743800.047
macromolecular complex subunit organizationGO:00439333390.047
cellular response to stressGO:00335542690.045
regulation of cellular protein metabolic processGO:00322682670.045
positive regulation of biosynthetic processGO:00098913190.044
cell cycle checkpointGO:000007520.043
regulation of rna biosynthetic processGO:20011413810.041
negative regulation of macromolecule biosynthetic processGO:00105581480.041
regulation of protein metabolic processGO:00512462890.039
cellular homeostasisGO:00197252520.038
cellular component assemblyGO:00226073600.038
response to peptideGO:19016522920.037
chemical homeostasisGO:00488782920.037
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.036
negative regulation of protein metabolic processGO:00512481140.036
response to inorganic substanceGO:00100353770.035
regulation of molecular functionGO:00650093980.035
negative regulation of rna metabolic processGO:00512531230.035
positive regulation of macromolecule biosynthetic processGO:00105572470.034
intracellular signal transductionGO:00355563140.034
positive regulation of rna biosynthetic processGO:19026801970.033
ion homeostasisGO:00508012120.033
regulation of transcription from rna polymerase ii promoterGO:00063572340.032
cellular ion homeostasisGO:00068731840.032
regulation of rna metabolic processGO:00512523910.031
negative regulation of rna biosynthetic processGO:19026791180.031
response to biotic stimulusGO:00096072260.031
negative regulation of cell deathGO:00605482290.031
cation homeostasisGO:00550801950.030
dna metabolic processGO:0006259960.030
reproductionGO:00000032450.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.029
cell projection organizationGO:00300303020.029
positive regulation of gene expressionGO:00106282440.029
negative regulation of rna splicingGO:003311930.029
protein complex subunit organizationGO:00718223020.029
head developmentGO:00603222470.028
cellular protein localizationGO:00346131220.028
nitrogen compound transportGO:00717052290.028
central nervous system developmentGO:00074173110.028
tissue developmentGO:00098882520.027
transcription dna templatedGO:00063513770.027
meiotic cell cycle processGO:190304630.027
translationGO:0006412350.027
macromolecular complex assemblyGO:00650032730.026
positive regulation of cellular biosynthetic processGO:00313282950.026
regulation of dna metabolic processGO:0051052600.026
ion transmembrane transportGO:00342203650.025
cell cycleGO:00070491010.025
protein localization to organelleGO:0033365570.025
cellular catabolic processGO:00442482950.025
rhythmic processGO:00485111560.025
positive regulation of rna metabolic processGO:00512542030.024
regulation of cellular localizationGO:00603412630.024
cellular chemical homeostasisGO:00550822470.024
reproductive processGO:00224143720.024
multi organism reproductive processGO:00447032620.024
transcription from rna polymerase ii promoterGO:00063662520.024
anatomical structure morphogenesisGO:00096532980.024
cellular amine metabolic processGO:0044106380.023
catabolic processGO:00090563510.023
protein localizationGO:00081041910.023
macromolecule localizationGO:00330362520.023
response to other organismGO:00517072200.023
transmembrane transportGO:00550854120.022
regulation of cellular component organizationGO:00511283680.021
cellular amino acid metabolic processGO:00065201070.021
regulation of transcription dna templatedGO:00063553740.021
negative regulation of programmed cell deathGO:00430691830.021
regulation of cell cycleGO:0051726730.021
homeostatic processGO:00425923310.021
regulation of signal transductionGO:00099663180.021
cellular component biogenesisGO:00440853680.020
regulation of cell differentiationGO:00455953200.020
dna integrity checkpointGO:003157020.020
response to purine containing compoundGO:00140741260.020
cellular response to cytokine stimulusGO:00713451270.020
posttranscriptional regulation of gene expressionGO:0010608370.019
negative regulation of apoptotic processGO:00430661810.019
cellular metal ion homeostasisGO:00068751720.019
chromatin modificationGO:0016568330.019
neuron developmentGO:00486662860.019
programmed cell deathGO:00125013920.019
positive regulation of molecular functionGO:00440932300.018
protein complex assemblyGO:00064612630.018
cell migrationGO:00164771970.018
negative regulation of cellular protein metabolic processGO:00322691060.018
cell cycle processGO:0022402570.018
regulation of apoptotic processGO:00429813350.018
neuron differentiationGO:00301823680.018
cellular cation homeostasisGO:00300031800.018
nucleobase containing small molecule metabolic processGO:00550863160.018
double strand break repairGO:000630210.018
regulation of proteasomal protein catabolic processGO:006113640.017
anterior posterior pattern specificationGO:000995210.017
regulation of translationGO:0006417270.017
protein phosphorylationGO:00064683450.017
response to external biotic stimulusGO:00432072210.017
chromosome segregationGO:000705920.017
positive regulation of transcription dna templatedGO:00458931970.017
single organism biosynthetic processGO:00447113420.017
positive regulation of cell developmentGO:00107201760.017
multicellular organism reproductionGO:00325042330.017
metal ion homeostasisGO:00550651860.017
multicellular organismal reproductive processGO:00486092330.016
regulation of organelle organizationGO:0033043800.016
response to transition metal nanoparticleGO:19902671220.016
chromosome organizationGO:0051276360.016
response to oxidative stressGO:00069791860.016
cellular response to oxygen containing compoundGO:19017013860.016
nucleobase containing compound catabolic processGO:00346551520.016
agingGO:00075682410.016
regulation of phosphorus metabolic processGO:00511743490.016
protein complex biogenesisGO:00702712630.016
histone h3 acetylationGO:004396620.016
positive regulation of cellular component organizationGO:00511302000.016
divalent inorganic cation homeostasisGO:00725071650.016
axis specificationGO:000979840.016
negative regulation of nucleic acid templated transcriptionGO:19035071170.016
carboxylic acid transportGO:00469421150.016
organic cyclic compound catabolic processGO:19013611750.016
regulation of homeostatic processGO:00328441010.016
regulation of cell proliferationGO:00421273590.015
response to cytokineGO:00340972150.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
negative regulation of cell cycle phase transitionGO:190198840.015
regulation of cellular amino acid metabolic processGO:000652120.015
brain developmentGO:00074202470.015
response to decreased oxygen levelsGO:00362932370.015
single organism reproductive processGO:00447022970.015
covalent chromatin modificationGO:0016569300.015
neuron projection developmentGO:00311752730.014
regulation of catalytic activityGO:00507903040.014
heterocycle catabolic processGO:00467001670.014
amine metabolic processGO:0009308380.014
mrna metabolic processGO:0016071200.014
negative regulation of signalingGO:00230571570.014
regulation of mrna splicing via spliceosomeGO:004802430.014
regulation of protein modification processGO:00313991940.014
single organism intracellular transportGO:19025821660.014
positive regulation of signal transductionGO:00099671750.014
organic substance catabolic processGO:19015753160.014
gland developmentGO:00487321550.014
regulation of programmed cell deathGO:00430673410.014
cellular response to endogenous stimulusGO:00714953770.014
organonitrogen compound biosynthetic processGO:19015661670.014
response to oxygen levelsGO:00704822650.014
peptidyl amino acid modificationGO:00181931260.014
circadian rhythmGO:0007623880.014
negative regulation of cell communicationGO:00106481580.013
gastrulationGO:000736920.013
mrna processingGO:0006397140.013
response to metal ionGO:00100382530.013
intracellular transportGO:00469071850.013
response to glucoseGO:00097491360.013
cellular macromolecule localizationGO:00707271220.013
positive regulation of protein modification processGO:00314011420.013
organic anion transportGO:00157111320.013
positive regulation of catalytic activityGO:00430851840.013
positive regulation of nervous system developmentGO:00519621780.013
response to extracellular stimulusGO:00099913800.013
response to hypoxiaGO:00016662310.013
cytoplasmic transportGO:00164821150.013
cell motilityGO:00488702020.013
cation transportGO:00068123820.013
proteolysisGO:00065081750.013
positive regulation of apoptotic processGO:00430651540.013
cellular response to nitrogen compoundGO:19016992100.013
cell cell signalingGO:00072673350.012
cellular component movementGO:00069282480.012
regulation of neurogenesisGO:00507672470.012
organic acid metabolic processGO:00060822920.012
response to reactive oxygen speciesGO:00003021200.012
cellular response to insulin stimulusGO:0032869810.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
response to ethanolGO:00454711620.012
microtubule organizing center organizationGO:003102310.012
negative regulation of transcription dna templatedGO:00458921160.012
vesicle mediated transportGO:00161921810.012
positive regulation of programmed cell deathGO:00430681570.012
regulation of intracellular signal transductionGO:19025312180.012
regulation of multicellular organismal developmentGO:20000263760.012
embryonic pattern specificationGO:000988010.012
nucleotide metabolic processGO:00091172790.012
regulation of ion transportGO:00432692450.012
negative regulation of signal transductionGO:0009968830.012
centrosome organizationGO:005129710.012
positive regulation of cell proliferationGO:00082842490.012
negative regulation of response to stimulusGO:00485851550.012
spermatogenesisGO:0007283990.012
regulation of neuron differentiationGO:00456642080.012
small gtpase mediated signal transductionGO:0007264360.012
protein oligomerizationGO:00512591910.012
positive regulation of cellular protein metabolic processGO:00322701670.012
response to estradiolGO:00323551640.011
regulation of cellular amine metabolic processGO:003323880.011
protein homooligomerizationGO:0051260910.011
organophosphate biosynthetic processGO:00904071430.011
epithelium developmentGO:0060429960.011
positive regulation of phosphorus metabolic processGO:00105622620.011
cell morphogenesisGO:00009021420.011
negative regulation of mitotic cell cycle phase transitionGO:190199130.011
regulation of cell developmentGO:00602842630.011
positive regulation of developmental processGO:00510942830.011
regulation of neuron projection developmentGO:00109751610.011
cellular response to interleukin 1GO:0071347370.011
mitotic cell cycleGO:0000278490.011
cellular response to organonitrogen compoundGO:00714171970.011
response to organophosphorusGO:00466831020.011
regulation of alternative mrna splicing via spliceosomeGO:000038120.011
positive regulation of neuron differentiationGO:00456661260.011
cytosolic calcium ion homeostasisGO:00514801400.011
single organism cellular localizationGO:19025801020.011
response to acid chemicalGO:00011012220.011
spindle organizationGO:000705120.011
positive regulation of catabolic processGO:0009896780.011
regulation of cell projection organizationGO:00313441750.011
protein targetingGO:0006605610.011
regulation of cellular ketone metabolic processGO:0010565270.011
g protein coupled receptor signaling pathwayGO:00071862420.011
organophosphate metabolic processGO:00196373700.011
chromatin organizationGO:0006325340.011
response to nutrient levelsGO:00316673700.011
response to woundingGO:00096112540.011
response to hexoseGO:00097461440.011
growthGO:00400071650.011
positive regulation of protein metabolic processGO:00512471780.011
regulation of nervous system developmentGO:00519602640.010
positive regulation of response to stimulusGO:00485842850.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
epithelial cell differentiationGO:0030855710.010
gamete generationGO:00072761240.010
positive regulation of phosphate metabolic processGO:00459372620.010
mrna stabilizationGO:004825520.010
response to toxic substanceGO:00096361330.010
dna damage checkpointGO:000007720.010
carboxylic acid metabolic processGO:00197522890.010
cytoskeleton dependent cytokinesisGO:006164020.010
regulation of phosphorylationGO:00423252480.010
cellular response to organic cyclic compoundGO:00714072020.010
negative regulation of cellular component organizationGO:0051129830.010

H2afx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
organ system cancerDOID:005068600.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
intestinal cancerDOID:1015500.012
colorectal cancerDOID:925600.012
gastrointestinal system cancerDOID:311900.012
colon cancerDOID:21900.012
large intestine cancerDOID:567200.012