IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Mark4

MAP/microtubule affinity-regulating kinase 4

Entrez: 680407
RGD: 1591792
Ensembl: ENSRNOG00000017069
UniProtKB: D4A6T9

Process Predictions
Disease Predictions

Mark4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
head development	GO:0060322	247	0.183
neuron development	GO:0048666	286	0.150
central nervous system development	GO:0007417	311	0.149
regulation of rna metabolic process	GO:0051252	391	0.147
regulation of rna biosynthetic process	GO:2001141	381	0.122
regulation of transcription dna templated	GO:0006355	374	0.105
regulation of nucleic acid templated transcription	GO:1903506	380	0.103
brain development	GO:0007420	247	0.095
cell part morphogenesis	GO:0032990	123	0.088
transcription from rna polymerase ii promoter	GO:0006366	252	0.082
regulation of multicellular organismal development	GO:2000026	376	0.071
carbohydrate derivative metabolic process	GO:1901135	346	0.071
nucleobase containing small molecule metabolic process	GO:0055086	316	0.070
cellular response to oxygen containing compound	GO:1901701	386	0.065
chemical homeostasis	GO:0048878	292	0.064
regulation of membrane potential	GO:0042391	110	0.064
nucleic acid templated transcription	GO:0097659	379	0.063
response to nutrient levels	GO:0031667	370	0.061
regulation of cell differentiation	GO:0045595	320	0.061
neuron differentiation	GO:0030182	368	0.061
neuron projection morphogenesis	GO:0048812	122	0.053
cell projection organization	GO:0030030	302	0.052
regulation of molecular function	GO:0065009	398	0.050
purine containing compound metabolic process	GO:0072521	253	0.048
neuron projection development	GO:0031175	273	0.048
metal ion homeostasis	GO:0055065	186	0.047
positive regulation of rna metabolic process	GO:0051254	203	0.044
glycosyl compound metabolic process	GO:1901657	182	0.044
organelle organization	GO:0006996	266	0.043
cell projection morphogenesis	GO:0048858	123	0.043
positive regulation of cell differentiation	GO:0045597	217	0.042
response to extracellular stimulus	GO:0009991	380	0.042
protein complex subunit organization	GO:0071822	302	0.041
regulation of neuron projection development	GO:0010975	161	0.040
regulation of nervous system development	GO:0051960	264	0.039
adult locomotory behavior	GO:0008344	4	0.039
cellular component assembly	GO:0022607	360	0.038
monovalent inorganic cation transport	GO:0015672	172	0.037
ion transmembrane transport	GO:0034220	365	0.034
positive regulation of neurogenesis	GO:0050769	165	0.034
rna biosynthetic process	GO:0032774	380	0.034
locomotion	GO:0040011	237	0.033
action potential	GO:0001508	54	0.033
ion homeostasis	GO:0050801	212	0.033
cellular chemical homeostasis	GO:0055082	247	0.033
neuronal action potential	GO:0019228	35	0.033
transmission of nerve impulse	GO:0019226	42	0.032
regulation of cell projection organization	GO:0031344	175	0.032
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.031
regulation of peptide transport	GO:0090087	87	0.030
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.029
cation transmembrane transport	GO:0098655	263	0.029
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.029
single organism reproductive process	GO:0044702	297	0.029
positive regulation of gene expression	GO:0010628	244	0.029
positive regulation of phosphorus metabolic process	GO:0010562	262	0.029
nucleoside phosphate metabolic process	GO:0006753	283	0.029
cellular calcium ion homeostasis	GO:0006874	160	0.028
neurological system process	GO:0050877	219	0.028
cation homeostasis	GO:0055080	195	0.028
purine ribonucleotide biosynthetic process	GO:0009152	81	0.028
positive regulation of neuron differentiation	GO:0045666	126	0.027
cell morphogenesis involved in differentiation	GO:0000904	119	0.027
regulation of signal transduction	GO:0009966	318	0.027
transmembrane transport	GO:0055085	412	0.027
cellular cation homeostasis	GO:0030003	180	0.027
glutamate receptor signaling pathway	GO:0007215	43	0.026
cellular component morphogenesis	GO:0032989	155	0.026
rna metabolic process	GO:0016070	406	0.025
negative regulation of transport	GO:0051051	136	0.025
cell morphogenesis	GO:0000902	142	0.025
organophosphate metabolic process	GO:0019637	370	0.025
regulation of neurogenesis	GO:0050767	247	0.025
calcium ion homeostasis	GO:0055074	162	0.025
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.024
transcription dna templated	GO:0006351	377	0.024
cellular homeostasis	GO:0019725	252	0.024
cellular component biogenesis	GO:0044085	368	0.024
signal release	GO:0023061	145	0.024
aging	GO:0007568	241	0.023
cellular metal ion homeostasis	GO:0006875	172	0.023
regulation of neuron differentiation	GO:0045664	208	0.023
myelination	GO:0042552	39	0.023
cellular potassium ion transport	GO:0071804	72	0.023
cytoskeleton organization	GO:0007010	111	0.023
inorganic ion transmembrane transport	GO:0098660	229	0.022
nucleotide metabolic process	GO:0009117	279	0.022
positive regulation of developmental process	GO:0051094	283	0.022
organonitrogen compound biosynthetic process	GO:1901566	167	0.022
response to oxidative stress	GO:0006979	186	0.021
negative regulation of cell development	GO:0010721	82	0.021
secretion by cell	GO:0032940	248	0.021
cellular response to external stimulus	GO:0071496	118	0.021
oxoacid metabolic process	GO:0043436	290	0.020
protein complex assembly	GO:0006461	263	0.020
regulation of cell development	GO:0060284	263	0.020
single organism behavior	GO:0044708	130	0.020
localization of cell	GO:0051674	202	0.020
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.020
circulatory system process	GO:0003013	183	0.020
cellular amino acid metabolic process	GO:0006520	107	0.020
hormone transport	GO:0009914	121	0.020
regeneration	GO:0031099	163	0.019
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.019
positive regulation of rna biosynthetic process	GO:1902680	197	0.018
forebrain development	GO:0030900	98	0.018
motor neuron axon guidance	GO:0008045	1	0.018
cellular catabolic process	GO:0044248	295	0.018
cellular component movement	GO:0006928	248	0.018
protein oligomerization	GO:0051259	191	0.018
response to vitamin	GO:0033273	131	0.018
cellular response to growth factor stimulus	GO:0071363	162	0.017
carbohydrate derivative biosynthetic process	GO:1901137	124	0.017
cell cycle	GO:0007049	101	0.017
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity	GO:2000311	11	0.017
ribose phosphate biosynthetic process	GO:0046390	87	0.017
positive regulation of neuron projection development	GO:0010976	99	0.017
negative regulation of response to stimulus	GO:0048585	155	0.017
positive regulation of nervous system development	GO:0051962	178	0.017
regulation of hormone levels	GO:0010817	187	0.016
bmp signaling pathway	GO:0030509	4	0.016
organic acid metabolic process	GO:0006082	292	0.016
response to cgmp	GO:0070305	3	0.016
dendrite development	GO:0016358	72	0.016
response to hexose	GO:0009746	144	0.016
axon development	GO:0061564	96	0.016
homeostatic process	GO:0042592	331	0.016
regulation of phosphate metabolic process	GO:0019220	349	0.016
negative regulation of cell communication	GO:0010648	158	0.015
regulation of cellular component organization	GO:0051128	368	0.015
cell adhesion	GO:0007155	110	0.015
nucleoside phosphate biosynthetic process	GO:1901293	102	0.015
cell cell signaling	GO:0007267	335	0.015
anterior posterior pattern specification	GO:0009952	1	0.015
cellular ion homeostasis	GO:0006873	184	0.015
blood circulation	GO:0008015	183	0.015
response to nutrient	GO:0007584	248	0.015
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.015
multicellular organismal signaling	GO:0035637	44	0.015
positive regulation of response to stimulus	GO:0048584	285	0.015
cell cycle checkpoint	GO:0000075	2	0.015
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.015
positive regulation of cell projection organization	GO:0031346	111	0.014
sexual reproduction	GO:0019953	148	0.014
reproductive process	GO:0022414	372	0.014
positive regulation of phosphate metabolic process	GO:0045937	262	0.014
multicellular organismal reproductive process	GO:0048609	233	0.014
positive regulation of transcription dna templated	GO:0045893	197	0.014
response to monosaccharide	GO:0034284	159	0.014
axon guidance	GO:0007411	24	0.014
peptide secretion	GO:0002790	86	0.014
regulation of peptide hormone secretion	GO:0090276	80	0.014
response to growth factor	GO:0070848	189	0.014
cell cycle process	GO:0022402	57	0.014
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.013
positive regulation of biosynthetic process	GO:0009891	319	0.013
nucleoside catabolic process	GO:0009164	126	0.013
vesicle mediated transport	GO:0016192	181	0.013
positive regulation of nucleotide metabolic process	GO:0045981	91	0.013
negative regulation of signal transduction	GO:0009968	83	0.013
purine ribonucleotide metabolic process	GO:0009150	227	0.013
heart process	GO:0003015	57	0.013
synaptic growth at neuromuscular junction	GO:0051124	1	0.013
regulation of cellular amine metabolic process	GO:0033238	8	0.013
positive regulation of cell proliferation	GO:0008284	249	0.013
guanosine containing compound metabolic process	GO:1901068	74	0.013
cell growth	GO:0016049	104	0.013
response to insulin	GO:0032868	133	0.013
regulation of gtpase activity	GO:0043087	57	0.013
cation transport	GO:0006812	382	0.013
negative regulation of developmental process	GO:0051093	125	0.013
embryonic pattern specification	GO:0009880	1	0.013
regulation of system process	GO:0044057	208	0.013
cytosolic calcium ion homeostasis	GO:0051480	140	0.012
negative regulation of signaling	GO:0023057	157	0.012
intracellular signal transduction	GO:0035556	314	0.012
dna integrity checkpoint	GO:0031570	2	0.012
response to glucocorticoid	GO:0051384	223	0.012
multi organism reproductive process	GO:0044703	262	0.012
peptide hormone secretion	GO:0030072	84	0.012
muscle system process	GO:0003012	115	0.012
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.012
ras protein signal transduction	GO:0007265	29	0.012
purine nucleotide metabolic process	GO:0006163	229	0.012
positive regulation of cellular biosynthetic process	GO:0031328	295	0.011
developmental process involved in reproduction	GO:0003006	159	0.011
regulation of glutamate receptor signaling pathway	GO:1900449	17	0.011
response to corticosteroid	GO:0031960	235	0.011
cellular response to cgmp	GO:0071321	2	0.011
peptide transport	GO:0015833	97	0.011
ribose phosphate metabolic process	GO:0019693	235	0.011
rhythmic process	GO:0048511	156	0.011
amide transport	GO:0042886	105	0.011
response to glucose	GO:0009749	136	0.011
regulation of phosphorus metabolic process	GO:0051174	349	0.011
regulation of blood pressure	GO:0008217	83	0.011
negative regulation of cellular component organization	GO:0051129	83	0.011
regulation of kinase activity	GO:0043549	117	0.011
cellular response to stress	GO:0033554	269	0.010
cellular response to nitrogen compound	GO:1901699	210	0.010
inorganic cation transmembrane transport	GO:0098662	202	0.010
regulation of gtp catabolic process	GO:0033124	58	0.010
glycosyl compound catabolic process	GO:1901658	126	0.010
negative regulation of macromolecule metabolic process	GO:0010605	260	0.010

Mark4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.033
	disease of anatomical entity	DOID:7	0	0.033

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