Rattus norvegicus

0 known processes

Tpcn1

two pore segment channel 1

Tpcn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.163
Human
ion transmembrane transportGO:00342203650.134
Human
catabolic processGO:00090563510.097
nucleobase containing small molecule metabolic processGO:00550863160.093
response to extracellular stimulusGO:00099913800.089
Rat
reproductive processGO:00224143720.085
regulation of molecular functionGO:00650093980.081
nucleotide metabolic processGO:00091172790.080
nucleoside phosphate metabolic processGO:00067532830.078
regulation of cellular component organizationGO:00511283680.075
regulation of catalytic activityGO:00507903040.074
negative regulation of metabolic processGO:00098923310.071
cation transportGO:00068123820.071
Human
positive regulation of multicellular organismal processGO:00512403870.069
organic acid metabolic processGO:00060822920.069
anion transportGO:00068201780.069
organonitrogen compound catabolic processGO:19015651790.069
single organism biosynthetic processGO:00447113420.068
organic substance catabolic processGO:19015753160.067
oxoacid metabolic processGO:00434362900.067
reproductionGO:00000032450.062
negative regulation of nitrogen compound metabolic processGO:00511721610.061
organic cyclic compound catabolic processGO:19013611750.061
ribose phosphate metabolic processGO:00196932350.060
protein phosphorylationGO:00064683450.060
apoptotic processGO:00069153810.059
glycosyl compound metabolic processGO:19016571820.059
organophosphate metabolic processGO:00196373700.058
purine nucleotide metabolic processGO:00061632290.058
neuron differentiationGO:00301823680.056
cellular component assemblyGO:00226073600.054
regulation of protein metabolic processGO:00512462890.053
protein complex biogenesisGO:00702712630.053
carbohydrate derivative metabolic processGO:19011353460.053
lipid metabolic processGO:00066292830.052
positive regulation of cell communicationGO:00106472710.052
cellular lipid metabolic processGO:00442552080.051
coenzyme metabolic processGO:0006732860.051
nucleoside triphosphate metabolic processGO:00091411440.051
carboxylic acid metabolic processGO:00197522890.050
response to peptideGO:19016522920.050
purine containing compound metabolic processGO:00725212530.050
cell projection organizationGO:00300303020.048
anatomical structure morphogenesisGO:00096532980.047
multicellular organism reproductionGO:00325042330.047
negative regulation of cellular metabolic processGO:00313242810.046
cellular catabolic processGO:00442482950.045
tissue developmentGO:00098882520.045
negative regulation of gene expressionGO:00106291990.045
developmental process involved in reproductionGO:00030061590.043
negative regulation of cellular biosynthetic processGO:00313271610.042
positive regulation of signalingGO:00230562700.041
regulation of apoptotic processGO:00429813350.041
secretionGO:00469033070.041
cellular homeostasisGO:00197252520.041
programmed cell deathGO:00125013920.040
neuron projection developmentGO:00311752730.040
cellular ketone metabolic processGO:0042180510.040
organic hydroxy compound metabolic processGO:19016151150.040
negative regulation of rna biosynthetic processGO:19026791180.039
positive regulation of cell deathGO:00109421840.039
aromatic compound catabolic processGO:00194391680.039
cellular response to oxygen containing compoundGO:19017013860.038
purine ribonucleoside triphosphate metabolic processGO:00092051400.038
negative regulation of rna metabolic processGO:00512531230.038
negative regulation of protein import into nucleus translocationGO:003315910.038
anion transmembrane transportGO:0098656770.038
nucleic acid templated transcriptionGO:00976593790.038
negative regulation of macromolecule metabolic processGO:00106052600.038
regulation of signal transductionGO:00099663180.037
purine ribonucleotide catabolic processGO:00091541360.037
cellular response to stressGO:00335542690.036
locomotionGO:00400112370.036
positive regulation of nitrogen compound metabolic processGO:00511733340.036
negative regulation of multicellular organismal processGO:00512412030.036
neuron developmentGO:00486662860.036
carbohydrate derivative catabolic processGO:19011361470.036
purine containing compound catabolic processGO:00725231380.036
gland developmentGO:00487321550.036
cation transmembrane transportGO:00986552630.035
Human
negative regulation of nucleobase containing compound metabolic processGO:00459341530.035
peptide hormone secretionGO:0030072840.034
cellular amine metabolic processGO:0044106380.034
single organism behaviorGO:00447081300.034
inorganic ion transmembrane transportGO:00986602290.034
Human
nucleoside phosphate catabolic processGO:19012921400.033
positive regulation of biosynthetic processGO:00098913190.033
ribonucleoside triphosphate catabolic processGO:00092031220.033
secretion by cellGO:00329402480.033
macromolecule localizationGO:00330362520.033
positive regulation of phosphate metabolic processGO:00459372620.033
regulation of cellular ketone metabolic processGO:0010565270.032
vesicle mediated transportGO:00161921810.032
metal ion transportGO:00300012890.032
Human
single organism reproductive processGO:00447022970.031
regulation of cellular localizationGO:00603412630.031
purine nucleoside monophosphate metabolic processGO:0009126840.031
nucleobase containing compound catabolic processGO:00346551520.031
purine ribonucleotide metabolic processGO:00091502270.031
positive regulation of cellular biosynthetic processGO:00313282950.031
cellular component biogenesisGO:00440853680.030
ribonucleotide metabolic processGO:00092592310.030
positive regulation of cell proliferationGO:00082842490.030
cell morphogenesisGO:00009021420.030
regulation of transcription from rna polymerase ii promoterGO:00063572340.030
organic anion transportGO:00157111320.030
organophosphate catabolic processGO:00464341480.030
single organism cellular localizationGO:19025801020.030
intracellular signal transductionGO:00355563140.030
organic acid biosynthetic processGO:0016053830.029
regulation of intracellular signal transductionGO:19025312180.029
multicellular organismal reproductive processGO:00486092330.029
multicellular organismal signalingGO:0035637440.029
regulation of hormone levelsGO:00108171870.029
negative regulation of macromolecule biosynthetic processGO:00105581480.029
chemical homeostasisGO:00488782920.029
small gtpase mediated signal transductionGO:0007264360.029
fatty acid metabolic processGO:0006631990.029
response to glucocorticoidGO:00513842230.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
nitrogen compound transportGO:00717052290.029
organelle organizationGO:00069962660.028
regulation of secretionGO:00510462240.028
negative regulation of transportGO:00510511360.028
multi organism reproductive processGO:00447032620.028
regulation of cell developmentGO:00602842630.028
multicellular organism growthGO:003526410.028
response to corticosteroidGO:00319602350.028
regulation of neurogenesisGO:00507672470.028
heterocycle catabolic processGO:00467001670.028
cellular amino acid metabolic processGO:00065201070.028
positive regulation of molecular functionGO:00440932300.027
homeostatic processGO:00425923310.027
negative regulation of nucleic acid templated transcriptionGO:19035071170.027
cell cell signalingGO:00072673350.027
regulation of programmed cell deathGO:00430673410.027
regulation of growthGO:00400081050.027
regulation of nucleic acid templated transcriptionGO:19035063800.027
positive regulation of macromolecule biosynthetic processGO:00105572470.027
response to peptide hormoneGO:00434342780.026
negative regulation of biosynthetic processGO:00098901680.026
cellular nitrogen compound catabolic processGO:00442701630.026
response to radiationGO:00093141370.026
nucleoside monophosphate metabolic processGO:0009123930.026
cellular component morphogenesisGO:00329891550.026
ribonucleoside metabolic processGO:00091191740.026
positive regulation of programmed cell deathGO:00430681570.025
agingGO:00075682410.025
hormone transportGO:00099141210.025
regulation of cellular amino acid metabolic processGO:000652120.025
rna metabolic processGO:00160704060.025
heart morphogenesisGO:000300730.025
intracellular transportGO:00469071850.025
head developmentGO:00603222470.025
purine nucleotide catabolic processGO:00061951360.025
single organism catabolic processGO:00447122830.025
oxidation reduction processGO:00551143040.024
regulation of anatomical structure morphogenesisGO:00226031410.024
response to metal ionGO:00100382530.024
negative regulation of transcription dna templatedGO:00458921160.024
nucleoside metabolic processGO:00091161790.024
cofactor metabolic processGO:0051186950.024
spindle organizationGO:000705120.024
behaviorGO:00076102050.024
response to carbohydrateGO:00097431830.023
negative regulation of cell deathGO:00605482290.023
regulation of secretion by cellGO:19035302080.023
regulation of membrane repolarizationGO:006030610.023
response to nutrient levelsGO:00316673700.023
Rat
neurological system processGO:00508772190.023
positive regulation of developmental processGO:00510942830.023
peptide transportGO:0015833970.023
organophosphate biosynthetic processGO:00904071430.023
amine metabolic processGO:0009308380.022
regulation of cellular protein metabolic processGO:00322682670.022
regulation of neuron differentiationGO:00456642080.022
positive regulation of cellular component organizationGO:00511302000.022
carboxylic acid biosynthetic processGO:0046394830.022
ras protein signal transductionGO:0007265290.022
purine ribonucleoside catabolic processGO:00461301240.022
macromolecular complex assemblyGO:00650032730.022
brain developmentGO:00074202470.022
reproductive structure developmentGO:00486081280.022
regulation of nervous system developmentGO:00519602640.022
purine nucleoside metabolic processGO:00422781690.022
response to growth factorGO:00708481890.022
protein oligomerizationGO:00512591910.021
purine nucleoside triphosphate metabolic processGO:00091441410.021
ribonucleoside monophosphate metabolic processGO:0009161880.021
regulation of cell motilityGO:20001451310.021
purine ribonucleoside monophosphate metabolic processGO:0009167840.021
response to woundingGO:00096112540.021
signal releaseGO:00230611450.021
cellular chemical homeostasisGO:00550822470.021
multi multicellular organism processGO:00447061380.021
peptide secretionGO:0002790860.021
lipid biosynthetic processGO:00086101280.021
regulation of phosphorus metabolic processGO:00511743490.020
regulation of ion transportGO:00432692450.020
cell adhesionGO:00071551100.020
regulation of phosphate metabolic processGO:00192203490.020
response to organophosphorusGO:00466831020.020
negative regulation of signalingGO:00230571570.020
carbohydrate metabolic processGO:00059751300.020
regulation of hormone secretionGO:00468831060.020
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252410.020
carbohydrate derivative biosynthetic processGO:19011371240.020
regulation of multicellular organismal developmentGO:20000263760.020
purine ribonucleoside metabolic processGO:00461281680.020
calcium ion transportGO:00068161310.019
Human
regulation of cell differentiationGO:00455953200.019
nucleoside catabolic processGO:00091641260.019
ribonucleoside catabolic processGO:00424541260.019
negative regulation of cell differentiationGO:0045596990.019
regulation of rna biosynthetic processGO:20011413810.019
carboxylic acid transportGO:00469421150.019
regulation of cell projection organizationGO:00313441750.019
action potentialGO:0001508540.019
regulation of neuron projection developmentGO:00109751610.019
asymmetric protein localizationGO:000810520.019
transcription dna templatedGO:00063513770.019
blood circulationGO:00080151830.019
ribonucleotide catabolic processGO:00092611360.019
growthGO:00400071650.019
regulation of transcription regulatory region dna bindingGO:200067740.018
purine nucleoside triphosphate catabolic processGO:00091461220.018
localization of cellGO:00516742020.018
circulatory system processGO:00030131830.018
cellular component movementGO:00069282480.018
cellular response to hormone stimulusGO:00328702470.018
cell fate determinationGO:000170920.018
regulation of system processGO:00440572080.018
negative regulation of molecular functionGO:00440921330.018
organic acid transportGO:00158491160.018
protein localization to membraneGO:0072657360.018
negative regulation of nervous system developmentGO:0051961790.018
regulation of protein phosphorylationGO:00019321830.018
atp metabolic processGO:0046034720.018
gliogenesisGO:0042063930.018
organonitrogen compound biosynthetic processGO:19015661670.018
response to ethanolGO:00454711620.018
proteolysisGO:00065081750.018
heart developmentGO:0007507720.018
response to acid chemicalGO:00011012220.018
embryonic appendage morphogenesisGO:003511340.018
regulation of membrane potentialGO:00423911100.018
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
regulation of cell morphogenesisGO:0022604770.018
sensory organ developmentGO:0007423740.018
regulation of anatomical structure sizeGO:00900661350.017
protein complex subunit organizationGO:00718223020.017
purine nucleoside catabolic processGO:00061521240.017
inorganic cation transmembrane transportGO:00986622020.017
Human
response to insulinGO:00328681330.017
monocarboxylic acid transportGO:0015718520.017
cellular metal ion homeostasisGO:00068751720.017
reproductive system developmentGO:00614581280.017
response to nutrientGO:00075842480.017
Rat
regulation of peptide secretionGO:0002791820.017
response to estrogenGO:00436272320.017
rna biosynthetic processGO:00327743800.017
gonad developmentGO:00084061040.017
macromolecular complex subunit organizationGO:00439333390.017
regulation of cellular amine metabolic processGO:003323880.017
retinal ganglion cell axon guidanceGO:003129010.017
cell motilityGO:00488702020.017
nucleotide catabolic processGO:00091661390.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
amide transportGO:00428861050.017
divalent inorganic cation homeostasisGO:00725071650.016
cellular ion homeostasisGO:00068731840.016
cellular response to alcoholGO:0097306870.016
ion homeostasisGO:00508012120.016
cation homeostasisGO:00550801950.016
positive regulation of response to stimulusGO:00485842850.016
positive regulation of gene expressionGO:00106282440.016
transcription from rna polymerase ii promoterGO:00063662520.016
regulation of ion transmembrane transportGO:00347651210.016
purine nucleoside monophosphate catabolic processGO:0009128550.016
positive regulation of cell differentiationGO:00455972170.016
metal ion homeostasisGO:00550651860.016
positive regulation of phosphorus metabolic processGO:00105622620.016
alcohol metabolic processGO:0006066770.016
small molecule catabolic processGO:0044282590.016
positive regulation of nervous system developmentGO:00519621780.016
regulation of homeostatic processGO:00328441010.016
response to glucoseGO:00097491360.016
negative regulation of protein metabolic processGO:00512481140.016
response to ketoneGO:19016541820.016
chromosome segregationGO:000705920.015
sensory perceptionGO:00076001010.015
cellular response to endogenous stimulusGO:00714953770.015
lipid localizationGO:0010876620.015
sex differentiationGO:00075481130.015
embryo developmentGO:0009790490.015
regulation of phosphorylationGO:00423252480.015
negative regulation of cell developmentGO:0010721820.015
positive regulation of phosphorylationGO:00423271770.015
divalent metal ion transportGO:00708381320.015
Human
monovalent inorganic cation transportGO:00156721720.015
cardiac chamber developmentGO:000320510.015
nucleoside triphosphate catabolic processGO:00091431230.015
positive regulation of apoptotic processGO:00430651540.015
positive regulation of catalytic activityGO:00430851840.015
response to hexoseGO:00097461440.015
membrane organizationGO:0061024940.015
negative regulation of neurogenesisGO:0050768780.015
regulation of response to woundingGO:1903034690.015
cellular response to growth factor stimulusGO:00713631620.015
purine ribonucleoside monophosphate catabolic processGO:0009169550.014
positive regulation of neuron differentiationGO:00456661260.014
regulation of cell adhesionGO:0030155520.014
regulation of metal ion transportGO:00109591180.014
ribonucleoside monophosphate catabolic processGO:0009158550.014
purine ribonucleoside triphosphate catabolic processGO:00092071220.014
positive regulation of protein phosphorylationGO:00019341350.014
positive regulation of protein modification processGO:00314011420.014
regulation of hydrolase activityGO:00513361430.014
epithelial cell differentiationGO:0030855710.014
muscle structure developmentGO:0061061870.014
protein complex assemblyGO:00064612630.014
cell cycleGO:00070491010.014
hormone secretionGO:00468791150.014
cellular response to nitrogen compoundGO:19016992100.014
regulation of insulin secretionGO:0050796650.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
response to inorganic substanceGO:00100353770.014
intracellular protein transportGO:0006886790.014
transmission of nerve impulseGO:0019226420.014
peptidyl amino acid modificationGO:00181931260.014
regulation of activation of jak2 kinase activityGO:001053410.014
cellular calcium ion homeostasisGO:00068741600.014
regulation of protein modification processGO:00313991940.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
negative regulation of cellular protein metabolic processGO:00322691060.013
carboxylic acid catabolic processGO:0046395490.013
cellular protein localizationGO:00346131220.013
cell morphogenesis involved in differentiationGO:00009041190.013
response to other organismGO:00517072200.013
negative regulation of cell communicationGO:00106481580.013
response to monosaccharideGO:00342841590.013
negative regulation of response to stimulusGO:00485851550.013
negative regulation of cell proliferationGO:00082851190.013
endocytosisGO:0006897840.013
peptidyl tyrosine phosphorylationGO:0018108720.013
circulatory system developmentGO:00723591340.013
monocarboxylic acid biosynthetic processGO:0072330480.013
regulation of locomotionGO:00400121480.013
regulation of peptide hormone secretionGO:0090276800.013
regulation of cell proliferationGO:00421273590.013
receptor metabolic processGO:0043112180.013
response to cytokineGO:00340972150.013
small molecule biosynthetic processGO:00442831240.012
vascular process in circulatory systemGO:0003018960.012
negative regulation of cell projection organizationGO:0031345500.012
cellular macromolecule localizationGO:00707271220.012
axis specificationGO:000979840.012
positive regulation of lipid biosynthetic processGO:0046889250.012
cellular response to hexose stimulusGO:0071331650.012
cellular cation homeostasisGO:00300031800.012
negative regulation of developmental processGO:00510931250.012
regulation of purine nucleotide metabolic processGO:19005421150.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
divalent inorganic cation transportGO:00725111340.012
Human
central nervous system developmentGO:00074173110.012
establishment of protein localizationGO:00451841410.012
blood vessel morphogenesisGO:0048514580.012
regulation of transcription dna templatedGO:00063553740.012
urogenital system developmentGO:0001655780.012
lipid storageGO:001991510.012
b cell differentiationGO:003018320.012
nicotinamide nucleotide metabolic processGO:0046496280.012
positive regulation of ion transportGO:0043270940.012
actin filament based processGO:0030029860.012
regulation of transferase activityGO:00513381230.012
cell cycle checkpointGO:000007520.012
regulation of small gtpase mediated signal transductionGO:0051056480.012
synaptic transmissionGO:00072682350.012
defense responseGO:00069521940.012
negative regulation of neuron differentiationGO:0045665620.012
atp catabolic processGO:0006200540.012
protein homooligomerizationGO:0051260910.012
positive regulation of rna biosynthetic processGO:19026801970.012
regulation of lipid metabolic processGO:0019216680.012
inflammatory responseGO:00069541500.012
neuronal action potentialGO:0019228350.012
positive regulation of cellular amine metabolic processGO:003324030.012
negative regulation of activation of jak2 kinase activityGO:190256910.012
regulation of cell migrationGO:00303341280.012
positive regulation of cell developmentGO:00107201760.012
positive regulation of transcription dna templatedGO:00458931970.012
nucleoside phosphate biosynthetic processGO:19012931020.012
salivary gland developmentGO:000743130.012
single organism intracellular transportGO:19025821660.012
epithelium developmentGO:0060429960.012
nucleoside monophosphate catabolic processGO:0009125560.012
positive regulation of secretionGO:00510471400.011
glycerol 3 phosphate metabolic processGO:000607220.011
regulation of response to stressGO:00801341260.011
pyridine containing compound metabolic processGO:0072524320.011
regulation of catabolic processGO:00098941130.011
monocarboxylic acid metabolic processGO:00327871520.011
cell part morphogenesisGO:00329901230.011
positive regulation of neuron projection developmentGO:0010976990.011
cytoplasmic transportGO:00164821150.011
dna metabolic processGO:0006259960.011
regulation of peptide transportGO:0090087870.011
insulin secretionGO:0030073690.011
response to oxidative stressGO:00069791860.011
glycerolipid metabolic processGO:0046486670.011
regulation of response to external stimulusGO:00321011060.011
eye morphogenesisGO:004859240.011
positive regulation of cell projection organizationGO:00313461110.011
sodium ion transportGO:0006814820.011
calcium ion homeostasisGO:00550741620.011
positive regulation of cellular protein metabolic processGO:00322701670.011
organic acid catabolic processGO:0016054490.011
developmental growthGO:00485891000.011
cardiac conductionGO:006133720.011
positive regulation of intracellular signal transductionGO:19025331380.011
negative regulation of transcription regulatory region dna bindingGO:200067820.011
single organism membrane organizationGO:0044802740.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
regulation of nucleotide metabolic processGO:00061401170.011
response to cgmpGO:007030530.011
protein autophosphorylationGO:0046777660.011
mechanoreceptor differentiationGO:004249020.011
axon developmentGO:0061564960.011
positive regulation of triglyceride biosynthetic processGO:001086740.011
positive regulation of receptor activityGO:200027340.011
renal system processGO:0003014400.010
positive regulation of transportGO:00510502450.010
purine containing compound biosynthetic processGO:0072522850.010
cellular response to organic cyclic compoundGO:00714072020.010
microvillus assemblyGO:003003320.010
positive regulation of fatty acid beta oxidationGO:003200040.010
response to transition metal nanoparticleGO:19902671220.010
response to estradiolGO:00323551640.010
negative regulation of catalytic activityGO:00430861030.010
glial cell differentiationGO:0010001650.010
wound healingGO:00420601220.010
regulation of protein kinase activityGO:00458591050.010
biological adhesionGO:00226101100.010
fatty acid biosynthetic processGO:0006633330.010
response to campGO:0051591910.010
single organism carbohydrate metabolic processGO:00447231180.010

Tpcn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
nervous system diseaseDOID:86300.057
disease of metabolismDOID:001466700.027
musculoskeletal system diseaseDOID:1700.025
inherited metabolic disorderDOID:65500.021
sensory system diseaseDOID:005015500.020
central nervous system diseaseDOID:33100.012
muscular diseaseDOID:008000000.011
brain diseaseDOID:93600.010