Rattus norvegicus

14 known processes

Tpcn2

two pore segment channel 2

Tpcn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component biogenesisGO:00440853680.105
cellular component assemblyGO:00226073600.096
carboxylic acid metabolic processGO:00197522890.090
oxoacid metabolic processGO:00434362900.087
organic acid metabolic processGO:00060822920.084
intracellular signal transductionGO:00355563140.078
regulation of cellular component organizationGO:00511283680.070
cellular amino acid metabolic processGO:00065201070.065
cellular amine metabolic processGO:0044106380.064
neuron differentiationGO:00301823680.059
regulation of protein metabolic processGO:00512462890.058
cellular component movementGO:00069282480.056
cellular component morphogenesisGO:00329891550.054
cell motilityGO:00488702020.053
cellular ketone metabolic processGO:0042180510.051
regulation of hormone levelsGO:00108171870.050
negative regulation of metabolic processGO:00098923310.050
response to hypoxiaGO:00016662310.048
response to inorganic substanceGO:00100353770.048
regulation of neuron differentiationGO:00456642080.047
response to woundingGO:00096112540.047
single organism biosynthetic processGO:00447113420.046
organelle organizationGO:00069962660.045
regulation of nervous system developmentGO:00519602640.045
response to other organismGO:00517072200.045
regulation of signal transductionGO:00099663180.043
multi organism reproductive processGO:00447032620.042
regulation of anatomical structure morphogenesisGO:00226031410.041
cell projection morphogenesisGO:00488581230.041
regulation of cellular ketone metabolic processGO:0010565270.041
apoptotic processGO:00069153810.041
cellular response to nitrogen compoundGO:19016992100.040
response to carbohydrateGO:00097431830.040
cell migrationGO:00164771970.040
regulation of cellular component movementGO:00512701500.040
positive regulation of cell communicationGO:00106472710.040
single organism reproductive processGO:00447022970.040
response to oxygen levelsGO:00704822650.040
regulation of cellular amine metabolic processGO:003323880.039
amine metabolic processGO:0009308380.039
organophosphate metabolic processGO:00196373700.039
response to growth factorGO:00708481890.039
cell morphogenesisGO:00009021420.039
response to extracellular stimulusGO:00099913800.039
secretionGO:00469033070.039
macromolecule localizationGO:00330362520.038
reproductive processGO:00224143720.038
axon developmentGO:0061564960.038
neuron developmentGO:00486662860.038
regulation of cell developmentGO:00602842630.037
regulation of cell morphogenesis involved in differentiationGO:0010769720.037
cell part morphogenesisGO:00329901230.037
response to decreased oxygen levelsGO:00362932370.036
regulation of secretionGO:00510462240.036
response to molecule of bacterial originGO:00022371940.035
regulation of molecular functionGO:00650093980.035
positive regulation of cellular component organizationGO:00511302000.035
protein complex assemblyGO:00064612630.035
ion transmembrane transportGO:00342203650.035
Human
cell morphogenesis involved in differentiationGO:00009041190.035
single organism organelle organizationGO:19025891800.035
programmed cell deathGO:00125013920.034
secretion by cellGO:00329402480.034
regulation of cell projection organizationGO:00313441750.034
localization of cellGO:00516742020.034
negative regulation of cell deathGO:00605482290.034
locomotionGO:00400112370.033
regulation of cellular amino acid metabolic processGO:000652120.033
response to acid chemicalGO:00011012220.033
cellular response to organonitrogen compoundGO:00714171970.033
multicellular organismal reproductive processGO:00486092330.033
regulation of cell morphogenesisGO:0022604770.033
response to peptide hormoneGO:00434342780.032
central nervous system developmentGO:00074173110.032
positive regulation of signalingGO:00230562700.032
anatomical structure morphogenesisGO:00096532980.031
macromolecular complex subunit organizationGO:00439333390.031
multicellular organism reproductionGO:00325042330.031
regulation of neurogenesisGO:00507672470.031
positive regulation of transportGO:00510502450.031
positive regulation of signal transductionGO:00099671750.031
carbohydrate derivative metabolic processGO:19011353460.031
response to oxidative stressGO:00069791860.031
positive regulation of multicellular organismal processGO:00512403870.031
neuron projection developmentGO:00311752730.030
hormone transportGO:00099141210.030
regulation of cell proliferationGO:00421273590.030
protein oligomerizationGO:00512591910.030
positive regulation of cell proliferationGO:00082842490.030
reproductionGO:00000032450.030
regulation of cellular protein metabolic processGO:00322682670.029
catabolic processGO:00090563510.029
protein complex biogenesisGO:00702712630.029
protein phosphorylationGO:00064683450.029
regulation of cell migrationGO:00303341280.029
response to estrogenGO:00436272320.028
nitrogen compound transportGO:00717052290.028
transcription dna templatedGO:00063513770.028
lipid metabolic processGO:00066292830.028
anion transportGO:00068201780.028
cellular response to endogenous stimulusGO:00714953770.028
response to ketoneGO:19016541820.028
cell projection organizationGO:00300303020.028
protein complex subunit organizationGO:00718223020.027
regulation of intracellular signal transductionGO:19025312180.027
response to purine containing compoundGO:00140741260.027
regulation of cell differentiationGO:00455953200.027
regulation of secretion by cellGO:19035302080.027
regulation of body fluid levelsGO:0050878900.027
cytoskeleton organizationGO:00070101110.027
negative regulation of cell communicationGO:00106481580.026
head developmentGO:00603222470.026
nucleobase containing small molecule metabolic processGO:00550863160.026
regulation of apoptotic processGO:00429813350.026
positive regulation of cellular amino acid metabolic processGO:004576410.026
response to bacteriumGO:00096172000.026
negative regulation of molecular functionGO:00440921330.025
response to cytokineGO:00340972150.025
rhythmic processGO:00485111560.025
cellular macromolecule localizationGO:00707271220.025
ribose phosphate metabolic processGO:00196932350.025
regulation of anatomical structure sizeGO:00900661350.025
regulation of system processGO:00440572080.025
vasculogenesisGO:000157030.025
cellular response to oxygen containing compoundGO:19017013860.025
brain developmentGO:00074202470.025
regulation of cell motilityGO:20001451310.025
muscle cell proliferationGO:0033002840.025
membrane organizationGO:0061024940.024
gliogenesisGO:0042063930.024
transmembrane transportGO:00550854120.024
Human
ion homeostasisGO:00508012120.024
Human
regulation of neuron projection developmentGO:00109751610.024
negative regulation of macromolecule metabolic processGO:00106052600.023
positive regulation of phosphorus metabolic processGO:00105622620.023
regulation of rna biosynthetic processGO:20011413810.023
response to nutrientGO:00075842480.023
negative regulation of signalingGO:00230571570.023
circulatory system processGO:00030131830.023
cellular homeostasisGO:00197252520.023
Human
response to peptideGO:19016522920.023
cellular lipid metabolic processGO:00442552080.023
nucleic acid templated transcriptionGO:00976593790.023
regulation of programmed cell deathGO:00430673410.022
cell cell signalingGO:00072673350.022
cellular catabolic processGO:00442482950.022
homeostatic processGO:00425923310.022
Human
regulation of axonogenesisGO:0050770370.022
regulation of phosphate metabolic processGO:00192203490.022
neuron projection morphogenesisGO:00488121220.022
signal transduction by phosphorylationGO:00230141440.022
regulation of phosphorylationGO:00423252480.022
cellular protein localizationGO:00346131220.022
nucleotide metabolic processGO:00091172790.022
actin filament based processGO:0030029860.022
cellular response to cytokine stimulusGO:00713451270.022
cell morphogenesis involved in neuron differentiationGO:00486671060.022
purine containing compound metabolic processGO:00725212530.022
regulation of multicellular organismal developmentGO:20000263760.022
positive regulation of cell developmentGO:00107201760.021
nucleoside phosphate metabolic processGO:00067532830.021
blood circulationGO:00080151830.021
negative regulation of protein metabolic processGO:00512481140.021
response to corticosteroidGO:00319602350.021
positive regulation of cell differentiationGO:00455972170.021
protein localizationGO:00081041910.021
chemical homeostasisGO:00488782920.021
Human
positive regulation of developmental processGO:00510942830.020
organic hydroxy compound metabolic processGO:19016151150.020
anatomical structure formation involved in morphogenesisGO:0048646830.020
purine ribonucleotide metabolic processGO:00091502270.020
regulation of cellular localizationGO:00603412630.020
negative regulation of programmed cell deathGO:00430691830.020
eye developmentGO:0001654500.020
regulation of transcription dna templatedGO:00063553740.020
response to glucocorticoidGO:00513842230.020
agingGO:00075682410.020
negative regulation of gene expressionGO:00106291990.020
response to lipopolysaccharideGO:00324961910.020
behaviorGO:00076102050.019
positive regulation of cellular component movementGO:00512721020.019
dendrite developmentGO:0016358720.019
small gtpase mediated signal transductionGO:0007264360.019
positive regulation of cellular amine metabolic processGO:003324030.019
cation transportGO:00068123820.019
Human
regulation of smooth muscle cell proliferationGO:0048660750.019
purine nucleotide metabolic processGO:00061632290.019
regulation of locomotionGO:00400121480.019
regenerationGO:00310991630.019
b cell differentiationGO:003018320.019
cellular chemical homeostasisGO:00550822470.019
Human
positive regulation of neurogenesisGO:00507691650.019
cellular response to stressGO:00335542690.019
ribonucleoside metabolic processGO:00091191740.019
peptidyl tyrosine modificationGO:0018212720.019
peptidyl amino acid modificationGO:00181931260.019
positive regulation of neuron projection developmentGO:0010976990.018
regulation of membrane potentialGO:00423911100.018
positive regulation of biosynthetic processGO:00098913190.018
positive regulation of cell projection organizationGO:00313461110.018
sexual reproductionGO:00199531480.018
negative regulation of cellular protein metabolic processGO:00322691060.018
anion transmembrane transportGO:0098656770.018
positive regulation of nitrogen compound metabolic processGO:00511733340.018
organic substance catabolic processGO:19015753160.018
response to hexoseGO:00097461440.018
positive regulation of cellular biosynthetic processGO:00313282950.017
rna biosynthetic processGO:00327743800.017
negative regulation of transportGO:00510511360.017
rna metabolic processGO:00160704060.017
ribonucleotide metabolic processGO:00092592310.017
negative regulation of multicellular organismal processGO:00512412030.017
carbohydrate derivative biosynthetic processGO:19011371240.017
signal releaseGO:00230611450.017
neurological system processGO:00508772190.017
response to nutrient levelsGO:00316673700.017
negative regulation of apoptotic processGO:00430661810.017
regulation of catalytic activityGO:00507903040.017
negative regulation of response to stimulusGO:00485851550.017
positive regulation of cell migrationGO:0030335960.017
smooth muscle cell proliferationGO:0048659770.016
regulation of phosphorus metabolic processGO:00511743490.016
regulation of peptide hormone secretionGO:0090276800.016
response to insulinGO:00328681330.016
positive regulation of gene expressionGO:00106282440.016
negative regulation of cellular component organizationGO:0051129830.016
metal ion homeostasisGO:00550651860.016
Human
regulation of proteasomal protein catabolic processGO:006113640.016
oxidation reduction processGO:00551143040.016
mesoderm developmentGO:000749820.016
learning or memoryGO:0007611900.016
cellular ion homeostasisGO:00068731840.016
Human
inorganic cation transmembrane transportGO:00986622020.016
Human
response to external biotic stimulusGO:00432072210.016
glycosyl compound metabolic processGO:19016571820.016
response to reactive oxygen speciesGO:00003021200.015
divalent inorganic cation transportGO:00725111340.015
Human
cation transmembrane transportGO:00986552630.015
Human
organonitrogen compound biosynthetic processGO:19015661670.015
calcium ion transportGO:00068161310.015
Human
transmission of nerve impulseGO:0019226420.015
positive regulation of secretionGO:00510471400.015
gamete generationGO:00072761240.015
growthGO:00400071650.015
chromosome segregationGO:000705920.015
positive regulation of cellular protein metabolic processGO:00322701670.015
negative regulation of catalytic activityGO:00430861030.015
development of primary sexual characteristicsGO:00451371070.015
regulation of hormone secretionGO:00468831060.015
hormone secretionGO:00468791150.015
organic anion transportGO:00157111320.015
protein homooligomerizationGO:0051260910.015
positive regulation of response to stimulusGO:00485842850.015
cellular modified amino acid metabolic processGO:0006575610.015
positive regulation of neuron differentiationGO:00456661260.015
reproductive structure developmentGO:00486081280.015
regulation of mapk cascadeGO:00434081160.015
gland developmentGO:00487321550.015
response to glucoseGO:00097491360.015
regulation of protein modification processGO:00313991940.015
macromolecular complex assemblyGO:00650032730.015
regulation of protein phosphorylationGO:00019321830.015
small molecule biosynthetic processGO:00442831240.015
positive regulation of nucleobase containing compound metabolic processGO:00459353190.015
reactive oxygen species metabolic processGO:0072593370.015
synaptic growth at neuromuscular junctionGO:005112410.015
dephosphorylationGO:0016311980.015
single organism behaviorGO:00447081300.014
regulation of cellular component sizeGO:0032535510.014
cellular cation homeostasisGO:00300031800.014
Human
regulation of nucleic acid templated transcriptionGO:19035063800.014
negative regulation of developmental processGO:00510931250.014
response to metal ionGO:00100382530.014
negative regulation of cellular metabolic processGO:00313242810.014
axonogenesisGO:0007409710.014
inorganic ion transmembrane transportGO:00986602290.014
Human
protein processingGO:0016485680.014
multicellular organismal signalingGO:0035637440.014
single organism membrane organizationGO:0044802740.014
ras protein signal transductionGO:0007265290.014
monovalent inorganic cation transportGO:00156721720.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
nucleoside catabolic processGO:00091641260.014
cellular response to growth factor stimulusGO:00713631620.014
intracellular transportGO:00469071850.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
Human
regulation of hydrolase activityGO:00513361430.014
regulation of cytokine productionGO:0001817560.014
response to ethanolGO:00454711620.014
vesicle mediated transportGO:00161921810.014
regulation of cell growthGO:0001558850.014
single organism catabolic processGO:00447122830.014
cell activationGO:0001775970.014
positive regulation of protein phosphorylationGO:00019341350.013
purine ribonucleoside metabolic processGO:00461281680.013
circadian rhythmGO:0007623880.013
alpha amino acid metabolic processGO:1901605710.013
regulation of rna metabolic processGO:00512523910.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
immune system processGO:00023762040.013
defense responseGO:00069521940.013
peptidyl tyrosine phosphorylationGO:0018108720.013
response to monosaccharideGO:00342841590.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
regulation of peptide secretionGO:0002791820.013
nucleoside metabolic processGO:00091161790.013
multicellular organism growthGO:003526410.013
cellular response to external stimulusGO:00714961180.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
organic acid transportGO:00158491160.013
single organism intracellular transportGO:19025821660.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
coenzyme metabolic processGO:0006732860.013
reactive oxygen species biosynthetic processGO:190340980.013
divalent inorganic cation homeostasisGO:00725071650.013
Human
neuronal action potentialGO:0019228350.013
fatty acid metabolic processGO:0006631990.013
positive regulation of protein metabolic processGO:00512471780.013
negative regulation of cell differentiationGO:0045596990.013
regulation of growthGO:00400081050.013
organonitrogen compound catabolic processGO:19015651790.012
synaptic transmissionGO:00072682350.012
protein maturationGO:0051604680.012
salivary gland developmentGO:000743130.012
positive regulation of molecular functionGO:00440932300.012
regulation of transcription from rna polymerase ii promoterGO:00063572340.012
regulation of response to external stimulusGO:00321011060.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of macromolecule biosynthetic processGO:00105572470.012
positive regulation of cell deathGO:00109421840.012
purine nucleoside catabolic processGO:00061521240.012
positive regulation of cell motilityGO:2000147970.012
sensory organ developmentGO:0007423740.012
organophosphate biosynthetic processGO:00904071430.012
response to estradiolGO:00323551640.012
developmental process involved in reproductionGO:00030061590.012
wound healingGO:00420601220.012
amide transportGO:00428861050.012
positive regulation of secretion by cellGO:19035321280.012
regulation of protein maturationGO:1903317500.012
cell growthGO:00160491040.012
leukocyte activationGO:0045321760.012
protein heterooligomerizationGO:0051291890.012
purine ribonucleoside catabolic processGO:00461301240.012
regulation of cellular catabolic processGO:00313291010.012
regulation of ion transportGO:00432692450.012
actin filament organizationGO:0007015420.012
male gamete generationGO:0048232990.012
positive regulation of locomotionGO:00400171020.012
carboxylic acid transportGO:00469421150.012
b cell mediated immunityGO:001972440.012
negative regulation of cell proliferationGO:00082851190.012
heart morphogenesisGO:000300730.011
cofactor metabolic processGO:0051186950.011
glycosyl compound catabolic processGO:19016581260.011
axis specificationGO:000979840.011
peptide hormone secretionGO:0030072840.011
carboxylic acid biosynthetic processGO:0046394830.011
developmental growthGO:00485891000.011
ribonucleotide catabolic processGO:00092611360.011
regulation of dendrite developmentGO:0050773590.011
response to hydrogen peroxideGO:0042542890.011
positive regulation of nervous system developmentGO:00519621780.011
endomembrane system organizationGO:0010256480.011
metal ion transportGO:00300012890.011
Human
hepaticobiliary system developmentGO:0061008900.011
actin cytoskeleton organizationGO:0030036730.011
alcohol metabolic processGO:0006066770.011
regulation of axon extensionGO:0030516240.011
mapk cascadeGO:00001651400.011
gonad developmentGO:00084061040.011
motor neuron axon guidanceGO:000804510.011
cellular response to oxidative stressGO:0034599760.011
action potentialGO:0001508540.011
nucleotide catabolic processGO:00091661390.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
regulation of neuron deathGO:19012141150.011
regulation of transmembrane transportGO:00347621220.011
nucleobase containing compound catabolic processGO:00346551520.011
ovulation cycleGO:0042698670.011
cellular nitrogen compound catabolic processGO:00442701630.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
regulation of organelle organizationGO:0033043800.011
carbohydrate derivative catabolic processGO:19011361470.011
chemosensory behaviorGO:000763520.011
response to tumor necrosis factorGO:0034612560.011
purine ribonucleotide catabolic processGO:00091541360.011
regulation of blood pressureGO:0008217830.011
regulation of leukocyte activationGO:0002694450.011
cellular protein complex assemblyGO:0043623440.011
lipid storageGO:001991510.011
reproductive system developmentGO:00614581280.011
regulation of synaptic transmissionGO:00508041410.011
carbohydrate metabolic processGO:00059751300.011
nucleoside triphosphate metabolic processGO:00091411440.011
positive regulation of transcription dna templatedGO:00458931970.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
regulation of proteolysisGO:0030162660.011
embryonic pattern specificationGO:000988010.011
heterocycle catabolic processGO:00467001670.011
regulation of peptide transportGO:0090087870.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
organic acid biosynthetic processGO:0016053830.011
regulation of catabolic processGO:00098941130.011
hormone metabolic processGO:0042445690.010
response to axon injuryGO:0048678590.010
negative regulation of secretionGO:0051048820.010
gastrulationGO:000736920.010
cation homeostasisGO:00550801950.010
Human
reactive nitrogen species metabolic processGO:200105710.010
cardiovascular system developmentGO:00723581340.010
negative regulation of cell developmentGO:0010721820.010
negative regulation of neurogenesisGO:0050768780.010
establishment of protein localizationGO:00451841410.010
regulation of response to stressGO:00801341260.010
purine ribonucleoside triphosphate metabolic processGO:00092051400.010
epithelial cell differentiation involved in kidney developmentGO:003585030.010
cytokine biosynthetic processGO:004208930.010

Tpcn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.059
disease of anatomical entityDOID:700.059
sensory system diseaseDOID:005015500.024
musculoskeletal system diseaseDOID:1700.020
central nervous system diseaseDOID:33100.020
eye diseaseDOID:561400.016
eye and adnexa diseaseDOID:149200.016
retinal diseaseDOID:567900.014
retinitis pigmentosaDOID:1058400.013
retinal degenerationDOID:846600.013
disease of metabolismDOID:001466700.012
muscular diseaseDOID:008000000.012
myopathyDOID:42300.012
muscle tissue diseaseDOID:6600.012