Rattus norvegicus

0 known processes

Izumo1

izumo sperm-egg fusion 1

Izumo1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.041
carbohydrate derivative metabolic processGO:19011353460.041
organic acid metabolic processGO:00060822920.040
organic substance catabolic processGO:19015753160.040
regulation of phosphorus metabolic processGO:00511743490.039
chemical homeostasisGO:00488782920.039
catabolic processGO:00090563510.039
positive regulation of nitrogen compound metabolic processGO:00511733340.038
regulation of multicellular organismal developmentGO:20000263760.038
neuron differentiationGO:00301823680.038
programmed cell deathGO:00125013920.038
oxoacid metabolic processGO:00434362900.038
response to extracellular stimulusGO:00099913800.038
cellular component assemblyGO:00226073600.037
regulation of molecular functionGO:00650093980.037
carboxylic acid metabolic processGO:00197522890.037
regulation of cell differentiationGO:00455953200.036
rna biosynthetic processGO:00327743800.036
regulation of phosphate metabolic processGO:00192203490.036
regulation of nucleic acid templated transcriptionGO:19035063800.035
cellular catabolic processGO:00442482950.035
cellular response to oxygen containing compoundGO:19017013860.035
cellular amino acid metabolic processGO:00065201070.035
cation transportGO:00068123820.035
response to inorganic substanceGO:00100353770.034
positive regulation of nucleobase containing compound metabolic processGO:00459353190.034
single organism biosynthetic processGO:00447113420.034
organophosphate metabolic processGO:00196373700.034
organelle organizationGO:00069962660.034
positive regulation of developmental processGO:00510942830.034
protein phosphorylationGO:00064683450.034
response to nutrient levelsGO:00316673700.034
regulation of rna biosynthetic processGO:20011413810.033
nucleic acid templated transcriptionGO:00976593790.033
single organism catabolic processGO:00447122830.033
apoptotic processGO:00069153810.033
transcription dna templatedGO:00063513770.033
positive regulation of multicellular organismal processGO:00512403870.032
cellular ketone metabolic processGO:0042180510.032
rna metabolic processGO:00160704060.032
nucleobase containing small molecule metabolic processGO:00550863160.032
amine metabolic processGO:0009308380.032
regulation of neurogenesisGO:00507672470.032
regulation of cell proliferationGO:00421273590.032
reproductive processGO:00224143720.032
homeostatic processGO:00425923310.031
regulation of cellular amino acid metabolic processGO:000652120.031
cellular amine metabolic processGO:0044106380.031
cellular component biogenesisGO:00440853680.031
macromolecular complex subunit organizationGO:00439333390.031
regulation of signal transductionGO:00099663180.030
regulation of apoptotic processGO:00429813350.030
positive regulation of cell communicationGO:00106472710.030
regulation of programmed cell deathGO:00430673410.030
positive regulation of biosynthetic processGO:00098913190.029
negative regulation of metabolic processGO:00098923310.029
regulation of cellular component organizationGO:00511283680.029
regulation of transcription dna templatedGO:00063553740.029
negative regulation of cellular metabolic processGO:00313242810.029
regulation of cellular protein metabolic processGO:00322682670.029
positive regulation of cellular biosynthetic processGO:00313282950.029
regulation of cell developmentGO:00602842630.029
regulation of rna metabolic processGO:00512523910.029
nucleoside phosphate metabolic processGO:00067532830.029
single organism reproductive processGO:00447022970.029
cell projection organizationGO:00300303020.028
secretionGO:00469033070.028
macromolecule localizationGO:00330362520.028
agingGO:00075682410.028
cellular homeostasisGO:00197252520.028
regulation of catalytic activityGO:00507903040.028
positive regulation of response to stimulusGO:00485842850.028
neuron projection developmentGO:00311752730.027
purine containing compound metabolic processGO:00725212530.027
response to oxygen levelsGO:00704822650.027
multi organism reproductive processGO:00447032620.027
transmembrane transportGO:00550854120.027
neuron developmentGO:00486662860.027
regulation of cellular amine metabolic processGO:003323880.027
transcription from rna polymerase ii promoterGO:00063662520.027
ion transmembrane transportGO:00342203650.027
positive regulation of cell proliferationGO:00082842490.027
regulation of phosphorylationGO:00423252480.026
regulation of intracellular signal transductionGO:19025312180.026
response to decreased oxygen levelsGO:00362932370.026
regulation of nervous system developmentGO:00519602640.026
nucleotide metabolic processGO:00091172790.026
cellular response to endogenous stimulusGO:00714953770.026
cellular response to stressGO:00335542690.026
cellular chemical homeostasisGO:00550822470.026
regulation of cellular ketone metabolic processGO:0010565270.026
positive regulation of cell differentiationGO:00455972170.026
response to other organismGO:00517072200.026
positive regulation of signalingGO:00230562700.025
response to peptideGO:19016522920.025
ribose phosphate metabolic processGO:00196932350.025
negative regulation of nitrogen compound metabolic processGO:00511721610.025
response to peptide hormoneGO:00434342780.025
aromatic compound catabolic processGO:00194391680.025
response to woundingGO:00096112540.025
regulation of cellular localizationGO:00603412630.025
anatomical structure morphogenesisGO:00096532980.025
response to hypoxiaGO:00016662310.025
regulation of membrane potentialGO:00423911100.024
response to metal ionGO:00100382530.024
regulation of neuron differentiationGO:00456642080.024
reproductionGO:00000032450.024
lipid metabolic processGO:00066292830.024
tissue developmentGO:00098882520.024
positive regulation of phosphate metabolic processGO:00459372620.024
regulation of protein metabolic processGO:00512462890.024
multicellular organism reproductionGO:00325042330.024
purine ribonucleotide metabolic processGO:00091502270.024
organic cyclic compound catabolic processGO:19013611750.023
protein complex biogenesisGO:00702712630.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
neurological system processGO:00508772190.023
muscle system processGO:00030121150.023
ribonucleotide metabolic processGO:00092592310.023
positive regulation of phosphorus metabolic processGO:00105622620.023
central nervous system developmentGO:00074173110.023
ion homeostasisGO:00508012120.023
response to corticosteroidGO:00319602350.023
response to glucocorticoidGO:00513842230.023
purine nucleotide metabolic processGO:00061632290.023
response to growth factorGO:00708481890.023
positive regulation of molecular functionGO:00440932300.022
nitrogen compound transportGO:00717052290.022
positive regulation of nervous system developmentGO:00519621780.022
negative regulation of macromolecule metabolic processGO:00106052600.022
regulation of system processGO:00440572080.022
macromolecular complex assemblyGO:00650032730.022
cell cell signalingGO:00072673350.022
cation homeostasisGO:00550801950.022
metal ion transportGO:00300012890.022
protein complex assemblyGO:00064612630.022
secretion by cellGO:00329402480.022
immune system processGO:00023762040.022
response to external biotic stimulusGO:00432072210.022
cation transmembrane transportGO:00986552630.022
cellular response to organic cyclic compoundGO:00714072020.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
head developmentGO:00603222470.022
positive regulation of transcription dna templatedGO:00458931970.022
defense responseGO:00069521940.022
response to estrogenGO:00436272320.021
cellular response to hormone stimulusGO:00328702470.021
positive regulation of rna metabolic processGO:00512542030.021
positive regulation of cell developmentGO:00107201760.021
positive regulation of gene expressionGO:00106282440.021
regulation of protein modification processGO:00313991940.021
purine nucleoside metabolic processGO:00422781690.021
positive regulation of cellular component organizationGO:00511302000.021
protein localizationGO:00081041910.021
heterocycle catabolic processGO:00467001670.021
negative regulation of cell deathGO:00605482290.021
cellular nitrogen compound catabolic processGO:00442701630.021
cellular response to nitrogen compoundGO:19016992100.021
negative regulation of apoptotic processGO:00430661810.021
response to bacteriumGO:00096172000.021
response to biotic stimulusGO:00096072260.021
protein complex subunit organizationGO:00718223020.021
cellular ion homeostasisGO:00068731840.021
ribonucleoside metabolic processGO:00091191740.020
glycosyl compound metabolic processGO:19016571820.020
nucleobase containing compound catabolic processGO:00346551520.020
heart morphogenesisGO:000300730.020
positive regulation of signal transductionGO:00099671750.020
positive regulation of neurogenesisGO:00507691650.020
multicellular organismal reproductive processGO:00486092330.020
regulation of protein phosphorylationGO:00019321830.020
positive regulation of phosphorylationGO:00423271770.020
nucleoside metabolic processGO:00091161790.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
cellular component movementGO:00069282480.020
response to nutrientGO:00075842480.020
organonitrogen compound biosynthetic processGO:19015661670.020
response to oxidative stressGO:00069791860.020
cellular response to organonitrogen compoundGO:00714171970.020
positive regulation of rna biosynthetic processGO:19026801970.020
positive regulation of transportGO:00510502450.020
inorganic ion transmembrane transportGO:00986602290.020
circulatory system processGO:00030131830.020
regulation of secretionGO:00510462240.020
response to carbohydrateGO:00097431830.020
metal ion homeostasisGO:00550651860.020
small gtpase mediated signal transductionGO:0007264360.020
organophosphate biosynthetic processGO:00904071430.019
blood circulationGO:00080151830.019
negative regulation of programmed cell deathGO:00430691830.019
purine ribonucleoside metabolic processGO:00461281680.019
regulation of secretion by cellGO:19035302080.019
single organism organelle organizationGO:19025891800.019
positive regulation of cellular amine metabolic processGO:003324030.019
organonitrogen compound catabolic processGO:19015651790.019
positive regulation of cell deathGO:00109421840.019
positive regulation of catalytic activityGO:00430851840.019
negative regulation of signalingGO:00230571570.019
regulation of response to stressGO:00801341260.019
response to acid chemicalGO:00011012220.019
negative regulation of gene expressionGO:00106291990.019
regulation of cell projection organizationGO:00313441750.019
regulation of neuron projection developmentGO:00109751610.019
negative regulation of cell communicationGO:00106481580.018
nucleoside phosphate catabolic processGO:19012921400.018
ras protein signal transductionGO:0007265290.018
divalent inorganic cation homeostasisGO:00725071650.018
organophosphate catabolic processGO:00464341480.018
cellular cation homeostasisGO:00300031800.018
brain developmentGO:00074202470.018
cellular lipid metabolic processGO:00442552080.018
regenerationGO:00310991630.018
cellular metal ion homeostasisGO:00068751720.018
cellular calcium ion homeostasisGO:00068741600.018
single organism intracellular transportGO:19025821660.017
purine containing compound catabolic processGO:00725231380.017
negative regulation of cellular biosynthetic processGO:00313271610.017
developmental process involved in reproductionGO:00030061590.017
regulation of ion transportGO:00432692450.017
response to ketoneGO:19016541820.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
response to toxic substanceGO:00096361330.017
behaviorGO:00076102050.017
synaptic transmissionGO:00072682350.017
inorganic cation transmembrane transportGO:00986622020.017
cellular response to growth factor stimulusGO:00713631620.017
negative regulation of natural killer cell mediated immunityGO:000271640.017
negative regulation of innate immune responseGO:004582440.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
intracellular transportGO:00469071850.017
sexual reproductionGO:00199531480.017
regulation of hydrolase activityGO:00513361430.017
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.017
growthGO:00400071650.017
monovalent inorganic cation transportGO:00156721720.017
g protein coupled receptor signaling pathwayGO:00071862420.017
response to monosaccharideGO:00342841590.016
carbohydrate derivative catabolic processGO:19011361470.016
positive regulation of neuron differentiationGO:00456661260.016
locomotionGO:00400112370.016
cell migrationGO:00164771970.016
calcium ion homeostasisGO:00550741620.016
positive regulation of apoptotic processGO:00430651540.016
negative regulation of transportGO:00510511360.016
proteolysisGO:00065081750.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
purine nucleotide catabolic processGO:00061951360.016
response to cytokineGO:00340972150.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
positive regulation of cellular protein metabolic processGO:00322701670.016
gland developmentGO:00487321550.016
nucleotide catabolic processGO:00091661390.016
positive regulation of secretionGO:00510471400.016
anion transportGO:00068201780.016
single organism behaviorGO:00447081300.016
purine ribonucleotide catabolic processGO:00091541360.016
protein transportGO:00150311320.016
response to hexoseGO:00097461440.016
response to molecule of bacterial originGO:00022371940.016
positive regulation of protein metabolic processGO:00512471780.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
response to estradiolGO:00323551640.015
cell type specific apoptotic processGO:00972851340.015
cellular response to lipidGO:00713962010.015
purine ribonucleoside catabolic processGO:00461301240.015
positive regulation of protein phosphorylationGO:00019341350.015
response to ethanolGO:00454711620.015
cytosolic calcium ion homeostasisGO:00514801400.015
muscle contractionGO:0006936880.015
vesicle mediated transportGO:00161921810.015
axis specificationGO:000979840.015
anterior posterior pattern specificationGO:000995210.015
negative regulation of multicellular organismal processGO:00512412030.015
localization of cellGO:00516742020.015
ribonucleotide catabolic processGO:00092611360.015
response to glucoseGO:00097491360.015
nucleoside triphosphate metabolic processGO:00091411440.015
protein oligomerizationGO:00512591910.015
negative regulation of response to stimulusGO:00485851550.015
regulation of hormone levelsGO:00108171870.015
positive regulation of intracellular signal transductionGO:19025331380.015
positive regulation of protein modification processGO:00314011420.014
reactive oxygen species metabolic processGO:0072593370.014
response to alkaloidGO:00432791320.014
action potentialGO:0001508540.014
response to reactive oxygen speciesGO:00003021200.014
nucleoside catabolic processGO:00091641260.014
positive regulation of cell projection organizationGO:00313461110.014
oxidation reduction processGO:00551143040.014
negative regulation of biosynthetic processGO:00098901680.014
regulation of anatomical structure sizeGO:00900661350.014
regulation of mapk cascadeGO:00434081160.014
response to lipopolysaccharideGO:00324961910.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
circulatory system developmentGO:00723591340.014
carbohydrate derivative biosynthetic processGO:19011371240.014
regulation of purine nucleotide metabolic processGO:19005421150.014
response to purine containing compoundGO:00140741260.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
response to transition metal nanoparticleGO:19902671220.014
positive regulation of programmed cell deathGO:00430681570.014
nucleoside triphosphate catabolic processGO:00091431230.014
inflammatory responseGO:00069541500.014
mapk cascadeGO:00001651400.013
gamete generationGO:00072761240.013
eye morphogenesisGO:004859240.013
negative regulation of molecular functionGO:00440921330.013
negative regulation of rna metabolic processGO:00512531230.013
regulation of nucleotide metabolic processGO:00061401170.013
purine nucleoside catabolic processGO:00061521240.013
cellular component morphogenesisGO:00329891550.013
establishment of protein localizationGO:00451841410.013
reproductive system developmentGO:00614581280.013
response to vitaminGO:00332731310.013
signal releaseGO:00230611450.013
glycosyl compound catabolic processGO:19016581260.013
regulation of cellular component movementGO:00512701500.013
cellular macromolecule localizationGO:00707271220.013
neuron deathGO:00709971270.013
regulation of cell migrationGO:00303341280.013
negative regulation of transcription dna templatedGO:00458921160.013
signal transduction by phosphorylationGO:00230141440.013
ribonucleoside triphosphate catabolic processGO:00092031220.013
cellular response to peptideGO:19016531330.013
cytoskeleton organizationGO:00070101110.013
immune responseGO:00069551040.013
regulation of immune system processGO:00026821230.013
response to radiationGO:00093141370.013
divalent metal ion transportGO:00708381320.013
divalent inorganic cation transportGO:00725111340.013
positive regulation of neuron projection developmentGO:0010976990.013
t cell tolerance inductionGO:000251730.013
regulation of cell motilityGO:20001451310.013
carbohydrate metabolic processGO:00059751300.013
regulation of transferase activityGO:00513381230.012
negative regulation of rna biosynthetic processGO:19026791180.012
cell motilityGO:00488702020.012
wound healingGO:00420601220.012
regulation of cellular catabolic processGO:00313291010.012
dephosphorylationGO:0016311980.012
rhythmic processGO:00485111560.012
regulation of anatomical structure morphogenesisGO:00226031410.012
sex differentiationGO:00075481130.012
embryonic pattern specificationGO:000988010.012
response to mechanical stimulusGO:00096121340.012
regulation of catabolic processGO:00098941130.012
reproductive structure developmentGO:00486081280.012
regulation of tube sizeGO:0035150890.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
negative regulation of cellular protein metabolic processGO:00322691060.012
regulation of neuron deathGO:19012141150.012
cell activationGO:0001775970.012
membrane organizationGO:0061024940.012
cellular protein localizationGO:00346131220.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
salivary gland developmentGO:000743130.012
response to insulinGO:00328681330.012
calcium ion transportGO:00068161310.012
cytoplasmic transportGO:00164821150.012
regulation of tolerance induction dependent upon immune responseGO:000265210.012
hepaticobiliary system developmentGO:0061008900.012
neuron projection morphogenesisGO:00488121220.012
chromosome segregationGO:000705920.012
negative regulation of phosphate metabolic processGO:0045936800.012
cellular response to external stimulusGO:00714961180.012
mesoderm developmentGO:000749820.012
cell part morphogenesisGO:00329901230.012
actin filament based processGO:0030029860.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
regulation of neuron apoptotic processGO:0043523830.012
positive regulation of secretion by cellGO:19035321280.012
regulation of canonical wnt signaling pathwayGO:006082840.012
gastrulationGO:000736920.012
organic anion transportGO:00157111320.012
regulation of locomotionGO:00400121480.012
regulation of blood vessel sizeGO:0050880890.011
negative regulation of protein metabolic processGO:00512481140.011
regulation of protein kinase activityGO:00458591050.011
regulation of muscle system processGO:0090257790.011
developmental growthGO:00485891000.011
liver developmentGO:0001889900.011
regulation of synaptic transmissionGO:00508041410.011
regulation of blood circulationGO:19035221100.011
hormone secretionGO:00468791150.011
lipid biosynthetic processGO:00086101280.011
development of primary sexual characteristicsGO:00451371070.011
reactive nitrogen species metabolic processGO:200105710.011
cell morphogenesisGO:00009021420.011
peptidyl amino acid modificationGO:00181931260.011
lipid storageGO:001991510.011
small molecule biosynthetic processGO:00442831240.011
single organism carbohydrate metabolic processGO:00447231180.011
regulation of kinase activityGO:00435491170.011
sensory organ developmentGO:0007423740.011
female pregnancyGO:00075651220.011
cellular response to steroid hormone stimulusGO:0071383930.011
regulation of organelle organizationGO:0033043800.011
dna metabolic processGO:0006259960.011
potassium ion transportGO:0006813970.011
learning or memoryGO:0007611900.011
positive regulation of mapk cascadeGO:0043410920.011
regulation of vesicle mediated transportGO:0060627810.011
spermatogenesisGO:0007283990.011
cellular response to peptide hormone stimulusGO:00713751200.011
peptide transportGO:0015833970.011
hormone transportGO:00099141210.011
amide transportGO:00428861050.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
organic acid transportGO:00158491160.011
male gamete generationGO:0048232990.011
regulation of growthGO:00400081050.011
gliogenesisGO:0042063930.011
positive regulation of immune system processGO:0002684900.011
circadian rhythmGO:0007623880.011
negative regulation of signal transductionGO:0009968830.011
cognitionGO:0050890920.011
ribose phosphate biosynthetic processGO:0046390870.011
rho protein signal transductionGO:0007266110.011
ribonucleoside catabolic processGO:00424541260.011
cellular response to alcoholGO:0097306870.011
gonad developmentGO:00084061040.011
multi multicellular organism processGO:00447061380.011
reactive oxygen species biosynthetic processGO:190340980.010
maintenance of locationGO:0051235170.010
nucleotide biosynthetic processGO:0009165980.010
cardiovascular system developmentGO:00723581340.010
regulation of metal ion transportGO:00109591180.010
neuronal action potentialGO:0019228350.010
negative regulation of catalytic activityGO:00430861030.010
multicellular organismal signalingGO:0035637440.010
response to organophosphorusGO:00466831020.010
negative regulation of phosphorus metabolic processGO:0010563800.010
vascular process in circulatory systemGO:0003018960.010
positive regulation of hydrolase activityGO:0051345860.010
gtp metabolic processGO:0046039720.010
defense response to gram negative bacteriumGO:005082930.010
muscle structure developmentGO:0061061870.010
negative regulation of neurogenesisGO:0050768780.010
positive regulation of tolerance inductionGO:000264510.010
cell morphogenesis involved in differentiationGO:00009041190.010
epithelium developmentGO:0060429960.010
negative regulation of secretionGO:0051048820.010
organ formationGO:004864530.010
carboxylic acid transportGO:00469421150.010
guanosine containing compound metabolic processGO:1901068740.010
multicellular organism growthGO:003526410.010
monocarboxylic acid metabolic processGO:00327871520.010
purine ribonucleotide biosynthetic processGO:0009152810.010
regulation of response to external stimulusGO:00321011060.010
sequestering of metal ionGO:005123890.010
cell projection morphogenesisGO:00488581230.010
regulation of reactive oxygen species metabolic processGO:2000377260.010
sequestering of calcium ionGO:005120880.010
striated muscle contractionGO:0006941440.010
negative regulation of cell developmentGO:0010721820.010
cell growthGO:00160491040.010

Izumo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.027
musculoskeletal system diseaseDOID:1700.026
sensory system diseaseDOID:005015500.017
disease of metabolismDOID:001466700.016
connective tissue diseaseDOID:6500.012
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
myopathyDOID:42300.012
bone diseaseDOID:008000100.011
central nervous system diseaseDOID:33100.010