Rattus norvegicus

0 known processes

Sgpl1

sphingosine-1-phosphate lyase 1

(Aliases: spl,Spgl1)

Sgpl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism biosynthetic processGO:00447113420.111
macromolecular complex subunit organizationGO:00439333390.097
cellular component assemblyGO:00226073600.084
regulation of multicellular organismal developmentGO:20000263760.070
response to extracellular stimulusGO:00099913800.070
regulation of protein metabolic processGO:00512462890.068
cellular response to endogenous stimulusGO:00714953770.063
cellular response to nitrogen compoundGO:19016992100.058
organic acid metabolic processGO:00060822920.057
organic substance catabolic processGO:19015753160.050
positive regulation of multicellular organismal processGO:00512403870.050
positive regulation of transportGO:00510502450.050
single organism catabolic processGO:00447122830.049
regulation of cellular ketone metabolic processGO:0010565270.046
organophosphate metabolic processGO:00196373700.045
macromolecular complex assemblyGO:00650032730.043
oxoacid metabolic processGO:00434362900.043
cellular component biogenesisGO:00440853680.042
response to nutrient levelsGO:00316673700.042
lipid metabolic processGO:00066292830.040
cellular catabolic processGO:00442482950.039
response to nutrientGO:00075842480.038
establishment of protein localizationGO:00451841410.037
protein localizationGO:00081041910.036
intracellular transportGO:00469071850.036
regulation of catalytic activityGO:00507903040.036
single organism intracellular transportGO:19025821660.036
homeostatic processGO:00425923310.036
carbohydrate derivative metabolic processGO:19011353460.035
cell cell signalingGO:00072673350.035
protein complex biogenesisGO:00702712630.035
cellular response to hormone stimulusGO:00328702470.035
regulation of cell developmentGO:00602842630.034
regulation of programmed cell deathGO:00430673410.034
catabolic processGO:00090563510.034
cellular ketone metabolic processGO:0042180510.034
lipid biosynthetic processGO:00086101280.033
carboxylic acid metabolic processGO:00197522890.033
positive regulation of response to stimulusGO:00485842850.032
regulation of molecular functionGO:00650093980.031
regulation of cellular component organizationGO:00511283680.031
purine containing compound metabolic processGO:00725212530.030
cellular response to organic cyclic compoundGO:00714072020.030
macromolecule localizationGO:00330362520.030
nucleoside phosphate metabolic processGO:00067532830.030
nucleotide metabolic processGO:00091172790.029
anatomical structure morphogenesisGO:00096532980.029
cellular amine metabolic processGO:0044106380.029
positive regulation of nitrogen compound metabolic processGO:00511733340.028
cellular amino acid metabolic processGO:00065201070.028
sterol transportGO:001591860.028
amine metabolic processGO:0009308380.028
nucleoside triphosphate catabolic processGO:00091431230.028
regulation of cell differentiationGO:00455953200.028
regulation of hormone levelsGO:00108171870.027
protein transportGO:00150311320.027
reproductive processGO:00224143720.027
negative regulation of multicellular organismal processGO:00512412030.027
head developmentGO:00603222470.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
telencephalon developmentGO:0021537620.026
central nervous system developmentGO:00074173110.025
regulation of cellular protein metabolic processGO:00322682670.025
positive regulation of signalingGO:00230562700.025
negative regulation of metabolic processGO:00098923310.025
positive regulation of phosphate metabolic processGO:00459372620.025
regulation of nervous system developmentGO:00519602640.024
positive regulation of neurogenesisGO:00507691650.024
programmed cell deathGO:00125013920.024
cellular lipid metabolic processGO:00442552080.024
regulation of cellular amino acid metabolic processGO:000652120.024
neuron developmentGO:00486662860.024
regulation of phosphate metabolic processGO:00192203490.023
regulation of apoptotic processGO:00429813350.023
positive regulation of developmental processGO:00510942830.023
positive regulation of cell deathGO:00109421840.023
protein phosphorylationGO:00064683450.023
response to metal ionGO:00100382530.023
synaptic growth at neuromuscular junctionGO:005112410.023
anion transportGO:00068201780.023
regulation of intracellular signal transductionGO:19025312180.023
organonitrogen compound catabolic processGO:19015651790.023
regulation of secretionGO:00510462240.023
nucleobase containing compound catabolic processGO:00346551520.022
purine containing compound catabolic processGO:00725231380.022
apoptotic processGO:00069153810.022
cellular component movementGO:00069282480.022
brain developmentGO:00074202470.022
ribose phosphate metabolic processGO:00196932350.022
positive regulation of protein metabolic processGO:00512471780.022
regulation of signal transductionGO:00099663180.022
anterior posterior pattern specificationGO:000995210.022
positive regulation of biosynthetic processGO:00098913190.022
positive regulation of phosphorus metabolic processGO:00105622620.021
protein complex subunit organizationGO:00718223020.021
positive regulation of apoptotic processGO:00430651540.021
response to peptideGO:19016522920.021
regulation of cell proliferationGO:00421273590.021
regulation of neurogenesisGO:00507672470.021
cell projection morphogenesisGO:00488581230.021
metal ion transportGO:00300012890.021
reproductionGO:00000032450.021
immune system processGO:00023762040.021
regulation of growthGO:00400081050.021
locomotionGO:00400112370.021
hormone metabolic processGO:0042445690.021
positive regulation of cell developmentGO:00107201760.021
organic cyclic compound catabolic processGO:19013611750.021
regulation of cellular amine metabolic processGO:003323880.021
cellular homeostasisGO:00197252520.021
neuron deathGO:00709971270.020
regulation of protein kinase activityGO:00458591050.020
regulation of protein modification processGO:00313991940.020
negative regulation of macromolecule metabolic processGO:00106052600.020
heterocycle catabolic processGO:00467001670.020
positive regulation of nervous system developmentGO:00519621780.020
regulation of neuron differentiationGO:00456642080.020
intracellular signal transductionGO:00355563140.020
positive regulation of molecular functionGO:00440932300.020
multicellular organism growthGO:003526410.020
oxidation reduction processGO:00551143040.020
positive regulation of cellular component organizationGO:00511302000.019
vesicle mediated transportGO:00161921810.019
protein heterooligomerizationGO:0051291890.019
regulation of phosphorylationGO:00423252480.019
positive regulation of cellular protein metabolic processGO:00322701670.019
cellular macromolecule localizationGO:00707271220.019
rna metabolic processGO:00160704060.019
regulation of phosphorus metabolic processGO:00511743490.019
cellular response to stressGO:00335542690.019
neuron projection developmentGO:00311752730.019
cellular response to organonitrogen compoundGO:00714171970.019
response to carbohydrateGO:00097431830.019
purine nucleoside triphosphate catabolic processGO:00091461220.019
neuron differentiationGO:00301823680.019
nucleoside metabolic processGO:00091161790.019
positive regulation of cellular biosynthetic processGO:00313282950.019
response to oxygen levelsGO:00704822650.019
lipid storageGO:001991510.018
neuron apoptotic processGO:0051402880.018
transmembrane transportGO:00550854120.018
cellular nitrogen compound catabolic processGO:00442701630.018
nucleobase containing small molecule metabolic processGO:00550863160.018
regulation of protein phosphorylationGO:00019321830.018
lipid localizationGO:0010876620.018
regulation of cell projection organizationGO:00313441750.018
negative regulation of cellular metabolic processGO:00313242810.018
endocytosisGO:0006897840.018
glycosyl compound metabolic processGO:19016571820.018
ion homeostasisGO:00508012120.017
response to estrogenGO:00436272320.017
intracellular protein transportGO:0006886790.017
cell projection organizationGO:00300303020.017
response to decreased oxygen levelsGO:00362932370.017
circulatory system processGO:00030131830.017
nucleoside triphosphate metabolic processGO:00091411440.017
protein complex assemblyGO:00064612630.017
negative regulation of gene expressionGO:00106291990.017
secretion by cellGO:00329402480.016
negative regulation of developmental processGO:00510931250.016
protein oligomerizationGO:00512591910.016
nucleoside phosphate catabolic processGO:19012921400.016
purine nucleotide metabolic processGO:00061632290.016
positive regulation of cell differentiationGO:00455972170.016
cellular response to oxygen containing compoundGO:19017013860.016
cellular protein localizationGO:00346131220.016
nucleoside catabolic processGO:00091641260.016
steroid metabolic processGO:0008202730.016
multicellular organismal reproductive processGO:00486092330.016
cellular response to lipidGO:00713962010.016
purine ribonucleoside metabolic processGO:00461281680.016
negative regulation of cell deathGO:00605482290.016
ribonucleoside metabolic processGO:00091191740.016
regulation of cellular localizationGO:00603412630.016
response to external biotic stimulusGO:00432072210.016
blood circulationGO:00080151830.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
cation transportGO:00068123820.016
negative regulation of transportGO:00510511360.016
embryonic pattern specificationGO:000988010.016
nucleotide catabolic processGO:00091661390.016
ras protein signal transductionGO:0007265290.015
glycerolipid metabolic processGO:0046486670.015
signal transduction by phosphorylationGO:00230141440.015
response to inorganic substanceGO:00100353770.015
positive regulation of cell communicationGO:00106472710.015
single organism reproductive processGO:00447022970.015
chemical homeostasisGO:00488782920.015
multi organism reproductive processGO:00447032620.015
response to hypoxiaGO:00016662310.015
negative regulation of programmed cell deathGO:00430691830.015
cell type specific apoptotic processGO:00972851340.015
organic anion transportGO:00157111320.015
growthGO:00400071650.015
aromatic compound catabolic processGO:00194391680.015
positive regulation of phosphorylationGO:00423271770.015
organic hydroxy compound transportGO:0015850770.015
negative regulation of protein metabolic processGO:00512481140.014
purine ribonucleotide metabolic processGO:00091502270.014
axis specificationGO:000979840.014
regulation of secretion by cellGO:19035302080.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
sterol homeostasisGO:005509230.014
response to insulinGO:00328681330.014
response to activityGO:0014823730.014
regulation of rna biosynthetic processGO:20011413810.014
purine nucleoside catabolic processGO:00061521240.014
single organism cellular localizationGO:19025801020.014
cellular response to insulin stimulusGO:0032869810.014
behaviorGO:00076102050.014
small molecule biosynthetic processGO:00442831240.014
carbohydrate derivative biosynthetic processGO:19011371240.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
small gtpase mediated signal transductionGO:0007264360.014
single organism carbohydrate metabolic processGO:00447231180.014
response to radiationGO:00093141370.014
response to peptide hormoneGO:00434342780.014
sexual reproductionGO:00199531480.014
secretionGO:00469033070.013
regulation of neuron deathGO:19012141150.013
maintenance of locationGO:0051235170.013
regulation of transcription dna templatedGO:00063553740.013
positive regulation of cellular amine metabolic processGO:003324030.013
regulation of system processGO:00440572080.013
regulation of rna metabolic processGO:00512523910.013
cellular response to external stimulusGO:00714961180.013
synaptic transmissionGO:00072682350.013
forebrain developmentGO:0030900980.013
cellular chemical homeostasisGO:00550822470.013
organophosphate catabolic processGO:00464341480.013
positive regulation of neuron differentiationGO:00456661260.013
gland developmentGO:00487321550.013
neuron projection morphogenesisGO:00488121220.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
positive regulation of programmed cell deathGO:00430681570.013
ribonucleotide metabolic processGO:00092592310.013
regulation of membrane potentialGO:00423911100.013
pallium developmentGO:0021543420.013
rna biosynthetic processGO:00327743800.013
eye morphogenesisGO:004859240.013
response to bacteriumGO:00096172000.013
multicellular organism reproductionGO:00325042330.012
regulation of neuron projection developmentGO:00109751610.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of signal transductionGO:00099671750.012
response to estradiolGO:00323551640.012
positive regulation of catalytic activityGO:00430851840.012
sulfur compound metabolic processGO:0006790700.012
vascular process in circulatory systemGO:0003018960.012
regulation of anatomical structure morphogenesisGO:00226031410.012
regulation of ion transportGO:00432692450.012
signal releaseGO:00230611450.012
nucleic acid templated transcriptionGO:00976593790.012
response to toxic substanceGO:00096361330.012
positive regulation of intracellular signal transductionGO:19025331380.012
lipid transportGO:0006869610.012
organelle organizationGO:00069962660.012
protein homooligomerizationGO:0051260910.012
response to vitaminGO:00332731310.012
cellular response to abiotic stimulusGO:0071214850.012
macromolecule catabolic processGO:0009057580.012
mapk cascadeGO:00001651400.012
negative regulation of molecular functionGO:00440921330.012
organic acid biosynthetic processGO:0016053830.012
regulation of response to stressGO:00801341260.012
localization of cellGO:00516742020.012
muscle structure developmentGO:0061061870.012
negative regulation of cellular protein metabolic processGO:00322691060.011
hormone biosynthetic processGO:0042446250.011
negative regulation of nervous system developmentGO:0051961790.011
response to other organismGO:00517072200.011
ion transmembrane transportGO:00342203650.011
cell morphogenesis involved in differentiationGO:00009041190.011
ribonucleoside catabolic processGO:00424541260.011
cell migrationGO:00164771970.011
metal ion homeostasisGO:00550651860.011
steroid biosynthetic processGO:0006694480.011
regulation of anatomical structure sizeGO:00900661350.011
agingGO:00075682410.011
organophosphate biosynthetic processGO:00904071430.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
cellular ion homeostasisGO:00068731840.011
response to alkaloidGO:00432791320.011
carboxylic acid biosynthetic processGO:0046394830.011
positive regulation of transcription dna templatedGO:00458931970.011
transcription dna templatedGO:00063513770.011
cellular metal ion homeostasisGO:00068751720.011
neuromuscular processGO:005090520.011
regulation of vesicle mediated transportGO:0060627810.011
cytoplasmic transportGO:00164821150.010
purine nucleotide catabolic processGO:00061951360.010
transcription from rna polymerase ii promoterGO:00063662520.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
response to acid chemicalGO:00011012220.010
chromosome segregationGO:000705920.010
nitrogen compound transportGO:00717052290.010
regulation of lipid metabolic processGO:0019216680.010
rhythmic processGO:00485111560.010
response to glucoseGO:00097491360.010
positive regulation of cell proliferationGO:00082842490.010
response to mechanical stimulusGO:00096121340.010
regulation of neuron apoptotic processGO:0043523830.010
developmental process involved in reproductionGO:00030061590.010
cell growthGO:00160491040.010
cell part morphogenesisGO:00329901230.010

Sgpl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
disease of anatomical entityDOID:700.018
musculoskeletal system diseaseDOID:1700.018
nervous system diseaseDOID:86300.014
inherited metabolic disorderDOID:65500.012