Rattus norvegicus

32 known processes

Pdk1

pyruvate dehydrogenase kinase, isozyme 1

(Aliases: MGC108625)

Pdk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism biosynthetic processGO:00447113420.104
Mouse
organic acid metabolic processGO:00060822920.097
Mouse
oxoacid metabolic processGO:00434362900.097
Mouse
response to oxygen levelsGO:00704822650.096
Human
response to nutrient levelsGO:00316673700.095
catabolic processGO:00090563510.088
oxidation reduction processGO:00551143040.081
carbohydrate catabolic processGO:0016052400.079
response to hypoxiaGO:00016662310.078
Human
carboxylic acid metabolic processGO:00197522890.070
Mouse
carbohydrate metabolic processGO:00059751300.067
Human
single organism catabolic processGO:00447122830.066
single organism carbohydrate metabolic processGO:00447231180.061
Human
coenzyme metabolic processGO:0006732860.061
Mouse
organophosphate metabolic processGO:00196373700.060
response to nutrientGO:00075842480.058
response to decreased oxygen levelsGO:00362932370.056
Human
regulation of cellular component organizationGO:00511283680.055
programmed cell deathGO:00125013920.054
Human
regulation of apoptotic processGO:00429813350.052
organelle organizationGO:00069962660.050
response to ketoneGO:19016541820.050
reproductive processGO:00224143720.049
regulation of programmed cell deathGO:00430673410.048
central nervous system developmentGO:00074173110.046
single organism carbohydrate catabolic processGO:0044724400.046
lipid metabolic processGO:00066292830.046
Mouse
negative regulation of metabolic processGO:00098923310.044
cellular catabolic processGO:00442482950.044
cellular response to stressGO:00335542690.043
Human
reproductionGO:00000032450.042
positive regulation of cellular component organizationGO:00511302000.041
negative regulation of cellular metabolic processGO:00313242810.041
regulation of multicellular organismal developmentGO:20000263760.040
neuron developmentGO:00486662860.040
single organism reproductive processGO:00447022970.039
response to glucocorticoidGO:00513842230.039
response to extracellular stimulusGO:00099913800.039
intracellular transportGO:00469071850.037
cellular amino acid metabolic processGO:00065201070.036
multicellular organism reproductionGO:00325042330.034
organophosphate biosynthetic processGO:00904071430.034
cellular response to oxygen containing compoundGO:19017013860.033
single organism organelle organizationGO:19025891800.033
secretionGO:00469033070.033
positive regulation of biosynthetic processGO:00098913190.032
apoptotic processGO:00069153810.032
Human
brain developmentGO:00074202470.032
positive regulation of multicellular organismal processGO:00512403870.032
cellular ketone metabolic processGO:0042180510.032
Mouse
response to corticosteroidGO:00319602350.031
multi organism reproductive processGO:00447032620.031
response to acid chemicalGO:00011012220.030
carbohydrate derivative metabolic processGO:19011353460.029
response to lipopolysaccharideGO:00324961910.029
multicellular organismal reproductive processGO:00486092330.029
regulation of cellular localizationGO:00603412630.028
response to other organismGO:00517072200.028
head developmentGO:00603222470.028
regulation of cell differentiationGO:00455953200.028
neuron differentiationGO:00301823680.027
neuron deathGO:00709971270.027
cellular response to external stimulusGO:00714961180.027
regulation of cell proliferationGO:00421273590.026
positive regulation of developmental processGO:00510942830.026
cellular response to oxidative stressGO:0034599760.026
Human
cell type specific apoptotic processGO:00972851340.026
nucleobase containing small molecule metabolic processGO:00550863160.026
macromolecule localizationGO:00330362520.026
cell cell signalingGO:00072673350.026
response to carbohydrateGO:00097431830.026
negative regulation of macromolecule metabolic processGO:00106052600.025
tissue developmentGO:00098882520.025
response to biotic stimulusGO:00096072260.025
positive regulation of cellular biosynthetic processGO:00313282950.025
rna biosynthetic processGO:00327743800.024
response to bacteriumGO:00096172000.024
organic substance catabolic processGO:19015753160.024
cellular amine metabolic processGO:0044106380.024
anatomical structure morphogenesisGO:00096532980.024
transcription dna templatedGO:00063513770.024
neuron apoptotic processGO:0051402880.024
regulation of nervous system developmentGO:00519602640.024
secretion by cellGO:00329402480.024
response to insulinGO:00328681330.024
chemical homeostasisGO:00488782920.024
monocarboxylic acid metabolic processGO:00327871520.024
Mouse
protein phosphorylationGO:00064683450.023
regenerationGO:00310991630.023
cellular chemical homeostasisGO:00550822470.023
positive regulation of nitrogen compound metabolic processGO:00511733340.023
response to peptide hormoneGO:00434342780.022
regulation of neuron differentiationGO:00456642080.022
negative regulation of cell deathGO:00605482290.022
positive regulation of neuron projection developmentGO:0010976990.022
synaptic transmissionGO:00072682350.022
nucleic acid templated transcriptionGO:00976593790.022
cytoplasmic transportGO:00164821150.022
positive regulation of neuron differentiationGO:00456661260.022
response to woundingGO:00096112540.022
amine metabolic processGO:0009308380.022
regulation of response to stressGO:00801341260.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
positive regulation of transportGO:00510502450.022
negative regulation of programmed cell deathGO:00430691830.022
lipid biosynthetic processGO:00086101280.021
positive regulation of cell deathGO:00109421840.021
response to inorganic substanceGO:00100353770.021
positive regulation of cell projection organizationGO:00313461110.021
regulation of system processGO:00440572080.021
single organism intracellular transportGO:19025821660.021
neuron projection developmentGO:00311752730.021
positive regulation of nervous system developmentGO:00519621780.021
response to ethanolGO:00454711620.021
single organism cellular localizationGO:19025801020.021
cellular carbohydrate metabolic processGO:0044262720.020
Human
regulation of neurogenesisGO:00507672470.020
cytosolic calcium ion homeostasisGO:00514801400.020
regulation of nucleic acid templated transcriptionGO:19035063800.020
negative regulation of signalingGO:00230571570.020
regulation of secretionGO:00510462240.020
regulation of transcription dna templatedGO:00063553740.020
gamete generationGO:00072761240.020
negative regulation of response to stimulusGO:00485851550.020
positive regulation of cell proliferationGO:00082842490.020
developmental process involved in reproductionGO:00030061590.020
rna metabolic processGO:00160704060.019
regulation of rna biosynthetic processGO:20011413810.019
behaviorGO:00076102050.019
sexual reproductionGO:00199531480.019
ion homeostasisGO:00508012120.019
cellular component assemblyGO:00226073600.019
nucleoside phosphate metabolic processGO:00067532830.019
phospholipid metabolic processGO:0006644610.019
regulation of cell developmentGO:00602842630.019
response to estrogenGO:00436272320.019
homeostatic processGO:00425923310.019
ribose phosphate metabolic processGO:00196932350.019
regulation of rna metabolic processGO:00512523910.019
cellular cation homeostasisGO:00300031800.019
agingGO:00075682410.018
regulation of cell projection organizationGO:00313441750.018
positive regulation of neurogenesisGO:00507691650.018
maintenance of locationGO:0051235170.018
response to molecule of bacterial originGO:00022371940.018
response to mechanical stimulusGO:00096121340.018
regulation of neuron projection developmentGO:00109751610.018
regulation of molecular functionGO:00650093980.018
neurological system processGO:00508772190.018
regulation of catabolic processGO:00098941130.018
small molecule catabolic processGO:0044282590.018
cellular component biogenesisGO:00440853680.018
intracellular signal transductionGO:00355563140.018
Human
regulation of metal ion transportGO:00109591180.018
calcium ion homeostasisGO:00550741620.018
cell projection organizationGO:00300303020.018
regulation of cellular ketone metabolic processGO:0010565270.017
Mouse
positive regulation of cell differentiationGO:00455972170.017
cellular response to hypoxiaGO:0071456510.017
Human
response to metal ionGO:00100382530.017
cellular homeostasisGO:00197252520.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
cellular ion homeostasisGO:00068731840.017
positive regulation of cellular amine metabolic processGO:003324030.017
positive regulation of cell developmentGO:00107201760.017
single organism behaviorGO:00447081300.017
purine ribonucleotide metabolic processGO:00091502270.017
response to estradiolGO:00323551640.017
negative regulation of apoptotic processGO:00430661810.017
regulation of cell motilityGO:20001451310.017
circulatory system processGO:00030131830.016
response to hexoseGO:00097461440.016
cellular calcium ion homeostasisGO:00068741600.016
protein complex assemblyGO:00064612630.016
positive regulation of ion transportGO:0043270940.016
generation of precursor metabolites and energyGO:0006091620.016
molting cycle processGO:002240420.016
hexose metabolic processGO:0019318580.016
Human
metal ion homeostasisGO:00550651860.016
macromolecular complex assemblyGO:00650032730.016
protein localization to organelleGO:0033365570.016
cellular response to hormone stimulusGO:00328702470.016
vesicle mediated transportGO:00161921810.016
blood circulationGO:00080151830.016
protein complex subunit organizationGO:00718223020.016
protein transportGO:00150311320.016
negative regulation of gene expressionGO:00106291990.016
negative regulation of transportGO:00510511360.016
establishment of protein localizationGO:00451841410.015
response to glucoseGO:00097491360.015
cellular response to oxygen levelsGO:0071453600.015
Human
protein complex biogenesisGO:00702712630.015
regulation of cellular catabolic processGO:00313291010.015
cation transportGO:00068123820.015
localization of cellGO:00516742020.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
membrane organizationGO:0061024940.015
monosaccharide metabolic processGO:0005996610.015
Human
negative regulation of multicellular organismal processGO:00512412030.015
cellular metal ion homeostasisGO:00068751720.015
cellular component movementGO:00069282480.015
ribose phosphate biosynthetic processGO:0046390870.015
heart morphogenesisGO:000300730.015
negative regulation of rna metabolic processGO:00512531230.015
negative regulation of cell proliferationGO:00082851190.015
cellular protein localizationGO:00346131220.014
response to peptideGO:19016522920.014
sequestering of calcium ionGO:005120880.014
divalent inorganic cation homeostasisGO:00725071650.014
response to oxidative stressGO:00069791860.014
Human
regulation of cellular amino acid metabolic processGO:000652120.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
response to external biotic stimulusGO:00432072210.014
regulation of growthGO:00400081050.014
cation homeostasisGO:00550801950.014
regulation of immune system processGO:00026821230.014
cellular response to lipidGO:00713962010.014
transcription from rna polymerase ii promoterGO:00063662520.014
negative regulation of cellular biosynthetic processGO:00313271610.014
regulation of phosphorus metabolic processGO:00511743490.014
Mouse
cellular macromolecule localizationGO:00707271220.014
nucleotide metabolic processGO:00091172790.014
carbohydrate derivative biosynthetic processGO:19011371240.013
positive regulation of rna metabolic processGO:00512542030.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
negative regulation of molecular functionGO:00440921330.013
purine nucleotide metabolic processGO:00061632290.013
cellular response to organonitrogen compoundGO:00714171970.013
ion transmembrane transportGO:00342203650.013
smooth muscle cell migrationGO:0014909360.013
regulation of catalytic activityGO:00507903040.013
protein processingGO:0016485680.013
male gamete generationGO:0048232990.013
sequestering of metal ionGO:005123890.013
glycosyl compound metabolic processGO:19016571820.013
organ regenerationGO:00311001010.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
chromosome segregationGO:000705920.013
alpha amino acid metabolic processGO:1901605710.013
response to campGO:0051591910.013
growthGO:00400071650.013
small gtpase mediated signal transductionGO:0007264360.012
alcohol metabolic processGO:0006066770.012
fatty acid metabolic processGO:0006631990.012
Mouse
regulation of secretion by cellGO:19035302080.012
carbohydrate biosynthetic processGO:0016051420.012
cellular response to nitrogen compoundGO:19016992100.012
response to vitaminGO:00332731310.012
response to toxic substanceGO:00096361330.012
positive regulation of cell communicationGO:00106472710.012
response to transition metal nanoparticleGO:19902671220.012
regulation of synaptic transmissionGO:00508041410.012
regulation of neuron deathGO:19012141150.012
intracellular protein transportGO:0006886790.012
response to purine containing compoundGO:00140741260.012
negative regulation of transcription dna templatedGO:00458921160.012
carbohydrate derivative catabolic processGO:19011361470.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
positive regulation of phosphorylationGO:00423271770.012
protein localizationGO:00081041910.012
regulation of phosphate metabolic processGO:00192203490.012
response to temperature stimulusGO:0009266940.012
ras protein signal transductionGO:0007265290.011
macromolecular complex subunit organizationGO:00439333390.011
positive regulation of phosphorus metabolic processGO:00105622620.011
regulation of cellular amine metabolic processGO:003323880.011
cellular response to endogenous stimulusGO:00714953770.011
cell motilityGO:00488702020.011
regulation of organelle organizationGO:0033043800.011
regulation of cell migrationGO:00303341280.011
cellular response to growth factor stimulusGO:00713631620.011
regulation of lipid metabolic processGO:0019216680.011
Mouse
fatty acid beta oxidationGO:0006635220.011
potassium ion transportGO:0006813970.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
response to cytokineGO:00340972150.011
regulation of muscle system processGO:0090257790.011
negative regulation of cell communicationGO:00106481580.011
positive regulation of rna biosynthetic processGO:19026801970.011
regulation of protein metabolic processGO:00512462890.011
regulation of signal transductionGO:00099663180.011
purine nucleoside metabolic processGO:00422781690.011
nitrogen compound transportGO:00717052290.011
regulation of ion transportGO:00432692450.011
protein oligomerizationGO:00512591910.011
response to hydrogen peroxideGO:0042542890.011
immune system processGO:00023762040.011
response to reactive oxygen speciesGO:00003021200.011
carboxylic acid biosynthetic processGO:0046394830.011
positive regulation of gene expressionGO:00106282440.011
regulation of cell growthGO:0001558850.011
peptidyl amino acid modificationGO:00181931260.011
transmembrane transportGO:00550854120.010
cellular modified amino acid metabolic processGO:0006575610.010
learning or memoryGO:0007611900.010
response to organophosphorusGO:00466831020.010
purine containing compound metabolic processGO:00725212530.010
purine nucleoside monophosphate metabolic processGO:0009126840.010
positive regulation of signalingGO:00230562700.010
g protein coupled receptor signaling pathwayGO:00071862420.010
glycerolipid metabolic processGO:0046486670.010
regulation of anatomical structure sizeGO:00900661350.010
regulation of intracellular signal transductionGO:19025312180.010
positive regulation of apoptotic processGO:00430651540.010
positive regulation of protein metabolic processGO:00512471780.010
nucleobase containing compound catabolic processGO:00346551520.010
actin filament based processGO:0030029860.010

Pdk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.014
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013