Rattus norvegicus

20 known processes

Pdk2

pyruvate dehydrogenase kinase, isozyme 2

Pdk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.748
Mouse
oxoacid metabolic processGO:00434362900.611
Mouse
carbohydrate catabolic processGO:0016052400.535
generation of precursor metabolites and energyGO:0006091620.503
single organism carbohydrate catabolic processGO:0044724400.475
organic acid metabolic processGO:00060822920.388
Mouse
single organism catabolic processGO:00447122830.372
catabolic processGO:00090563510.363
carboxylic acid catabolic processGO:0046395490.317
organic acid catabolic processGO:0016054490.305
cellular amino acid metabolic processGO:00065201070.301
regulation of cell maturationGO:190342930.284
regulation of cell developmentGO:00602842630.249
pyruvate metabolic processGO:0006090270.241
Mouse
glycogen metabolic processGO:0005977230.195
monocarboxylic acid metabolic processGO:00327871520.193
Mouse
cellular catabolic processGO:00442482950.184
glucan metabolic processGO:0044042230.182
energy derivation by oxidation of organic compoundsGO:0015980460.174
organic acid biosynthetic processGO:0016053830.172
response to extracellular stimulusGO:00099913800.167
Mouse
cellular glucan metabolic processGO:0006073230.159
organic substance catabolic processGO:19015753160.146
neuron developmentGO:00486662860.143
response to purine containing compoundGO:00140741260.131
cellular polysaccharide metabolic processGO:0044264230.131
polysaccharide metabolic processGO:0005976250.130
oxidation reduction processGO:00551143040.129
regulation of neurogenesisGO:00507672470.123
fatty acid metabolic processGO:0006631990.119
Mouse
neuron projection developmentGO:00311752730.119
cellular response to endogenous stimulusGO:00714953770.116
Mouse
cellular response to stressGO:00335542690.115
Human
carboxylic acid biosynthetic processGO:0046394830.114
response to hexoseGO:00097461440.108
regulation of multicellular organismal developmentGO:20000263760.107
response to nutrient levelsGO:00316673700.107
Mouse
regulation of cellular ketone metabolic processGO:0010565270.107
Mouse
neuron differentiationGO:00301823680.101
cellular carbohydrate metabolic processGO:0044262720.101
Mouse
response to nutrientGO:00075842480.094
Mouse
cellular response to oxygen containing compoundGO:19017013860.092
Human Mouse
cellular ketone metabolic processGO:0042180510.091
Mouse
hormone transportGO:00099141210.090
cation homeostasisGO:00550801950.090
Mouse
regulation of cell differentiationGO:00455953200.089
carbohydrate metabolic processGO:00059751300.089
Mouse
response to monosaccharideGO:00342841590.084
central nervous system developmentGO:00074173110.083
cellular homeostasisGO:00197252520.080
cellular lipid metabolic processGO:00442552080.079
Mouse
negative regulation of multicellular organismal processGO:00512412030.078
regulation of nucleic acid templated transcriptionGO:19035063800.078
regulation of phosphorylationGO:00423252480.078
brain developmentGO:00074202470.077
single organism carbohydrate metabolic processGO:00447231180.072
Mouse
positive regulation of multicellular organismal processGO:00512403870.072
cellular component biogenesisGO:00440853680.072
nitrogen compound transportGO:00717052290.072
protein phosphorylationGO:00064683450.071
regulation of response to stressGO:00801341260.068
intracellular signal transductionGO:00355563140.065
Human
signal releaseGO:00230611450.065
cellular amine metabolic processGO:0044106380.064
negative regulation of cell communicationGO:00106481580.064
macromolecular complex assemblyGO:00650032730.063
cation transportGO:00068123820.062
regulation of cellular amine metabolic processGO:003323880.060
regulation of cellular catabolic processGO:00313291010.059
negative regulation of metabolic processGO:00098923310.059
cellular component assemblyGO:00226073600.058
response to organophosphorusGO:00466831020.056
response to carbohydrateGO:00097431830.055
negative regulation of signalingGO:00230571570.055
regulation of rna biosynthetic processGO:20011413810.055
single organism biosynthetic processGO:00447113420.054
Mouse
hormone secretionGO:00468791150.054
regulation of cellular component organizationGO:00511283680.054
small molecule catabolic processGO:0044282590.053
regulation of cellular amino acid metabolic processGO:000652120.053
transcription dna templatedGO:00063513770.053
lipid biosynthetic processGO:00086101280.053
cellular chemical homeostasisGO:00550822470.053
regulation of intracellular signal transductionGO:19025312180.052
cellular calcium ion homeostasisGO:00068741600.051
organic anion transportGO:00157111320.050
organophosphate metabolic processGO:00196373700.050
positive regulation of transportGO:00510502450.050
cellular metal ion homeostasisGO:00068751720.048
signal transduction by phosphorylationGO:00230141440.048
peptide hormone secretionGO:0030072840.048
ion homeostasisGO:00508012120.047
Mouse
cellular component maintenanceGO:004395440.047
response to estrogenGO:00436272320.046
negative regulation of intracellular signal transductionGO:1902532380.046
protein complex assemblyGO:00064612630.046
response to estradiolGO:00323551640.045
metal ion transportGO:00300012890.045
response to woundingGO:00096112540.045
peptidyl amino acid modificationGO:00181931260.045
response to inorganic substanceGO:00100353770.044
response to ketoneGO:19016541820.043
transmembrane transportGO:00550854120.042
cellular response to external stimulusGO:00714961180.042
Mouse
regulation of chromosome segregationGO:005198310.041
multi organism reproductive processGO:00447032620.041
regulation of ion transportGO:00432692450.040
regulation of system processGO:00440572080.040
blood circulationGO:00080151830.039
secretionGO:00469033070.039
reproductive processGO:00224143720.039
cellular response to organonitrogen compoundGO:00714171970.039
Mouse
regulation of programmed cell deathGO:00430673410.038
monocarboxylic acid biosynthetic processGO:0072330480.038
negative regulation of macromolecule metabolic processGO:00106052600.038
ion transmembrane transportGO:00342203650.038
regulation of cellular localizationGO:00603412630.038
response to glucoseGO:00097491360.037
fatty acid oxidationGO:0019395290.037
negative regulation of phosphorus metabolic processGO:0010563800.037
cellular response to peptideGO:19016531330.037
Mouse
phospholipid metabolic processGO:0006644610.037
amine metabolic processGO:0009308380.037
response to temperature stimulusGO:0009266940.036
regulation of lipid metabolic processGO:0019216680.036
Mouse
macromolecule localizationGO:00330362520.036
regulation of nervous system developmentGO:00519602640.036
regulation of meiotic cell cycleGO:005144530.036
positive regulation of cell developmentGO:00107201760.035
cation transmembrane transportGO:00986552630.035
head developmentGO:00603222470.034
metal ion homeostasisGO:00550651860.034
cellular carbohydrate catabolic processGO:0044275200.034
regulation of mapk cascadeGO:00434081160.034
positive regulation of catabolic processGO:0009896780.033
positive regulation of cell differentiationGO:00455972170.033
positive regulation of gene expressionGO:00106282440.033
neurological system processGO:00508772190.033
heart processGO:0003015570.033
cellular cation homeostasisGO:00300031800.033
peptide secretionGO:0002790860.033
homeostatic processGO:00425923310.032
Mouse
neuron projection morphogenesisGO:00488121220.032
macromolecule catabolic processGO:0009057580.032
regulation of protein metabolic processGO:00512462890.032
positive regulation of developmental processGO:00510942830.032
protein tetramerizationGO:0051262380.032
response to oxidative stressGO:00069791860.031
Human
regulation of apoptotic processGO:00429813350.030
anterior posterior pattern specificationGO:000995210.030
negative regulation of gene expressionGO:00106291990.030
negative regulation of response to stimulusGO:00485851550.030
transcription from rna polymerase ii promoterGO:00063662520.029
negative regulation of erk1 and erk2 cascadeGO:007037390.029
chemical homeostasisGO:00488782920.029
Mouse
ras protein signal transductionGO:0007265290.029
cellular amino acid catabolic processGO:0009063210.029
amide transportGO:00428861050.028
regulation of proteasomal protein catabolic processGO:006113640.028
response to nitrosative stressGO:005140920.028
response to toxic substanceGO:00096361330.028
cell fate commitment involved in pattern specificationGO:006058120.028
cell projection organizationGO:00300303020.028
divalent inorganic cation homeostasisGO:00725071650.028
regulation of neuron differentiationGO:00456642080.027
cell cell signalingGO:00072673350.027
positive regulation of nucleic acid templated transcriptionGO:19035081970.027
response to oxygen levelsGO:00704822650.027
positive regulation of rna metabolic processGO:00512542030.027
heart contractionGO:0060047570.027
hexose metabolic processGO:0019318580.027
Mouse
agingGO:00075682410.027
single organism reproductive processGO:00447022970.027
secretion by cellGO:00329402480.027
action potentialGO:0001508540.027
regulation of peptide hormone secretionGO:0090276800.027
protein homooligomerizationGO:0051260910.026
growthGO:00400071650.026
response to alkaloidGO:00432791320.026
programmed cell deathGO:00125013920.026
Human
positive regulation of triglyceride metabolic processGO:009020840.026
dicarboxylic acid metabolic processGO:0043648420.026
positive regulation of neurogenesisGO:00507691650.026
energy reserve metabolic processGO:0006112250.026
synaptic transmissionGO:00072682350.025
positive regulation of cellular amine metabolic processGO:003324030.025
negative regulation of phosphate metabolic processGO:0045936800.025
monovalent inorganic cation transportGO:00156721720.025
rna metabolic processGO:00160704060.025
positive regulation of nitrogen compound metabolic processGO:00511733340.025
carbohydrate biosynthetic processGO:0016051420.025
Mouse
regulation of hormone secretionGO:00468831060.025
protein complex subunit organizationGO:00718223020.024
axis specificationGO:000979840.024
embryonic pattern specificationGO:000988010.024
lipid metabolic processGO:00066292830.024
Mouse
developmental maturationGO:0021700250.024
regulation of rna metabolic processGO:00512523910.024
regulation of neurotransmitter levelsGO:0001505420.024
negative regulation of signal transductionGO:0009968830.024
maintenance of locationGO:0051235170.023
response to axon injuryGO:0048678590.023
regulation of protein modification processGO:00313991940.023
transmission of nerve impulseGO:0019226420.023
positive regulation of cellular biosynthetic processGO:00313282950.023
muscle structure developmentGO:0061061870.023
insulin secretionGO:0030073690.023
peptide transportGO:0015833970.022
regulation of membrane potentialGO:00423911100.022
positive regulation of phosphorylationGO:00423271770.022
rna localizationGO:000640340.022
negative regulation of programmed cell deathGO:00430691830.022
regulation of phosphorus metabolic processGO:00511743490.022
Mouse
organophosphate biosynthetic processGO:00904071430.022
microtubule cytoskeleton organizationGO:0000226250.022
positive regulation of cellular component organizationGO:00511302000.022
organic hydroxy compound metabolic processGO:19016151150.022
positive regulation of hormone secretionGO:0046887650.021
positive regulation of intracellular signal transductionGO:19025331380.021
fatty acid beta oxidationGO:0006635220.021
cellular response to organic cyclic compoundGO:00714072020.021
organelle organizationGO:00069962660.021
cellular sodium ion homeostasisGO:000688340.021
small molecule biosynthetic processGO:00442831240.021
positive regulation of programmed cell deathGO:00430681570.021
glucose metabolic processGO:0006006520.021
Mouse
sequestering of triglycerideGO:003073010.021
purine nucleoside diphosphate metabolic processGO:000913590.021
response to antibioticGO:0046677390.021
multi multicellular organism processGO:00447061380.021
circulatory system processGO:00030131830.021
regulation of secretion by cellGO:19035302080.020
cellular potassium ion transportGO:0071804720.020
regulation of homeostatic processGO:00328441010.020
oxaloacetate metabolic processGO:000610760.020
anatomical structure morphogenesisGO:00096532980.020
cofactor metabolic processGO:0051186950.020
Mouse
positive regulation of rna biosynthetic processGO:19026801970.020
cellular response to lipidGO:00713962010.020
response to external biotic stimulusGO:00432072210.020
smooth muscle cell proliferationGO:0048659770.020
regulation of erk1 and erk2 cascadeGO:0070372410.020
positive regulation of transcription dna templatedGO:00458931970.020
regulation of phosphate metabolic processGO:00192203490.020
positive regulation of biosynthetic processGO:00098913190.020
carbohydrate derivative metabolic processGO:19011353460.020
macromolecular complex subunit organizationGO:00439333390.020
proteolysis involved in cellular protein catabolic processGO:0051603190.020
inorganic cation transmembrane transportGO:00986622020.019
positive regulation of ion transportGO:0043270940.019
regulation of response to woundingGO:1903034690.019
multicellular organismal reproductive processGO:00486092330.019
negative regulation of rna metabolic processGO:00512531230.019
response to other organismGO:00517072200.019
glycosyl compound metabolic processGO:19016571820.018
nucleobase containing small molecule metabolic processGO:00550863160.018
regulation of molecular functionGO:00650093980.018
embryonic axis specificationGO:000057810.018
monosaccharide metabolic processGO:0005996610.018
Mouse
regulation of cell projection organizationGO:00313441750.018
axon developmentGO:0061564960.018
regulation of neuron projection developmentGO:00109751610.018
protein complex biogenesisGO:00702712630.018
cellular response to growth factor stimulusGO:00713631620.018
regulation of signal transductionGO:00099663180.018
apoptotic signaling pathwayGO:0097190270.018
Human
response to genisteinGO:003359540.018
regulation of response to external stimulusGO:00321011060.017
sexual reproductionGO:00199531480.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
nucleoside phosphate biosynthetic processGO:19012931020.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
positive regulation of secretionGO:00510471400.017
regulation of cellular component biogenesisGO:0044087860.017
calcium ion homeostasisGO:00550741620.017
negative regulation of cellular metabolic processGO:00313242810.017
cellular response to hormone stimulusGO:00328702470.017
Mouse
regulation of cellular response to stressGO:0080135490.017
apoptotic processGO:00069153810.017
Human
regulation of insulin secretionGO:0050796650.017
learning or memoryGO:0007611900.016
regulation of cell proliferationGO:00421273590.016
regulation of anatomical structure sizeGO:00900661350.016
regulation of synaptic transmissionGO:00508041410.016
protein catabolic processGO:0030163300.016
immune system processGO:00023762040.016
positive regulation of lipid metabolic processGO:0045834330.016
positive regulation of phosphorus metabolic processGO:00105622620.016
positive regulation of ion transmembrane transportGO:0034767240.016
regulation of secretionGO:00510462240.016
sodium ion transportGO:0006814820.016
axon ensheathmentGO:0008366400.016
single organism cellular localizationGO:19025801020.016
hormone mediated signaling pathwayGO:0009755230.016
intracellular transportGO:00469071850.016
nucleic acid templated transcriptionGO:00976593790.015
negative regulation of cell deathGO:00605482290.015
cellular macromolecule localizationGO:00707271220.015
regulation of metal ion transportGO:00109591180.015
response to ethanolGO:00454711620.015
cytoplasmic transportGO:00164821150.015
developmental process involved in reproductionGO:00030061590.015
positive regulation of peptide hormone secretionGO:0090277500.015
necroptotic processGO:007026620.015
regulation of protein phosphorylationGO:00019321830.015
response to decreased oxygen levelsGO:00362932370.015
cell morphogenesis involved in differentiationGO:00009041190.015
response to reactive oxygen speciesGO:00003021200.015
Human
regulation of peptide transportGO:0090087870.015
neuronal action potentialGO:0019228350.015
regulation of catabolic processGO:00098941130.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
purine ribonucleotide biosynthetic processGO:0009152810.015
single organism organelle organizationGO:19025891800.015
ubiquitin dependent protein catabolic processGO:0006511140.015
negative regulation of cell developmentGO:0010721820.015
negative regulation of nervous system developmentGO:0051961790.015
carboxylic acid transportGO:00469421150.015
cellular response to nitrogen compoundGO:19016992100.015
Mouse
response to heatGO:0009408600.015
carbohydrate derivative biosynthetic processGO:19011371240.014
vascular process in circulatory systemGO:0003018960.014
regulation of ossificationGO:0030278320.014
positive regulation of peptide secretionGO:0002793520.014
divalent inorganic cation transportGO:00725111340.014
positive regulation of molecular functionGO:00440932300.014
microtubule based processGO:0007017360.014
positive regulation of cell maturationGO:190343130.014
ribonucleoside metabolic processGO:00091191740.014
purine containing compound biosynthetic processGO:0072522850.014
alpha amino acid catabolic processGO:1901606200.014
regulation of lipid biosynthetic processGO:0046890380.014
inflammatory responseGO:00069541500.014
hexose transportGO:0008645290.014
regulation of transcription dna templatedGO:00063553740.014
cellular response to nutrient levelsGO:0031669600.014
Mouse
regulation of peptide secretionGO:0002791820.014
chromosome segregationGO:000705920.014
response to starvationGO:0042594590.014
cellular response to oxygen levelsGO:0071453600.014
udp glucose metabolic processGO:000601130.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
cell junction maintenanceGO:003433110.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
dicarboxylic acid catabolic processGO:004364910.013
ribose phosphate metabolic processGO:00196932350.013
single organism intracellular transportGO:19025821660.013
cellular response to hexose stimulusGO:0071331650.013
regulation of fatty acid metabolic processGO:0019217180.013
Mouse
multicellular organismal signalingGO:0035637440.013
response to growth factorGO:00708481890.013
negative regulation of mapk cascadeGO:0043409200.013
inorganic ion transmembrane transportGO:00986602290.013
eye developmentGO:0001654500.013
regulation of cytokine productionGO:0001817560.013
cellular modified amino acid metabolic processGO:0006575610.013
purine containing compound metabolic processGO:00725212530.013
regulation of microtubule cytoskeleton organizationGO:0070507140.013
cellular ion homeostasisGO:00068731840.013
positive regulation of response to stimulusGO:00485842850.013
calcium ion transportGO:00068161310.013
regulation of intracellular transportGO:0032386650.013
cellular response to biotic stimulusGO:0071216590.013
detection of visible lightGO:000958430.012
branched chain amino acid metabolic processGO:000908140.012
cell part morphogenesisGO:00329901230.012
negative regulation of protein phosphorylationGO:0001933440.012
glucose homeostasisGO:0042593750.012
Mouse
regulation of blood vessel sizeGO:0050880890.012
regulation of tube sizeGO:0035150890.012
regulation of anion transportGO:0044070430.012
regulation of gluconeogenesisGO:000611140.012
Mouse
regulation of immune responseGO:0050776550.012
mitotic cell cycleGO:0000278490.012
multicellular organism reproductionGO:00325042330.012
reproductionGO:00000032450.012
negative regulation of cellular component organizationGO:0051129830.012
branched chain amino acid catabolic processGO:000908340.012
response to acid chemicalGO:00011012220.012
regulation of cellular protein metabolic processGO:00322682670.012
acetyl coa metabolic processGO:0006084170.012
Mouse
gamete generationGO:00072761240.012
regulation of cell cycle processGO:0010564310.012
cytokine productionGO:0001816610.012
positive regulation of cell communicationGO:00106472710.012
reactive oxygen species metabolic processGO:0072593370.012
anion transportGO:00068201780.012
lipid storageGO:001991510.012
response to corticosteroidGO:00319602350.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
small gtpase mediated signal transductionGO:0007264360.011
cellular response to acid chemicalGO:0071229750.011
phospholipid biosynthetic processGO:0008654290.011
cellular response to molecule of bacterial originGO:0071219560.011
cellular response to acidic phGO:007146820.011
protein transportGO:00150311320.011
cell projection morphogenesisGO:00488581230.011
negative regulation of response to biotic stimulusGO:000283240.011
regulation of calcium ion transportGO:0051924770.011
adp biosynthetic processGO:000617280.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
nucleotide metabolic processGO:00091172790.011
nucleoside phosphate metabolic processGO:00067532830.011
glucan biosynthetic processGO:0009250150.011
regulation of neural precursor cell proliferationGO:2000177160.011
cell junction organizationGO:0034330210.011
brain renin angiotensin systemGO:000203530.011
cholesterol homeostasisGO:004263230.011
negative regulation of cellular biosynthetic processGO:00313271610.011
immune responseGO:00069551040.011
digestive system developmentGO:0055123410.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
forebrain developmentGO:0030900980.011
endocrine system developmentGO:0035270300.011
hexose biosynthetic processGO:0019319150.011
Mouse
negative regulation of transportGO:00510511360.011
chromosome organizationGO:0051276360.011
mapk cascadeGO:00001651400.011
negative regulation of cellular amino acid metabolic processGO:004576300.011
purine ribonucleoside biosynthetic processGO:0046129210.011
rna biosynthetic processGO:00327743800.011
liver developmentGO:0001889900.011
positive regulation of cellular catabolic processGO:0031331710.011
fatty acid transportGO:0015908250.011
cellular response to cytokine stimulusGO:00713451270.011
erk1 and erk2 cascadeGO:0070371480.010
negative regulation of cellular amine metabolic processGO:003323930.010
response to osmotic stressGO:0006970420.010
tissue developmentGO:00098882520.010
negative regulation of cellular protein metabolic processGO:00322691060.010
adherens junction maintenanceGO:003433410.010
camera type eye developmentGO:0043010480.010
response to bacteriumGO:00096172000.010
negative regulation of phosphorylationGO:0042326570.010
muscle contractionGO:0006936880.010
negative regulation of reactive oxygen species metabolic processGO:200037870.010
regulation of transmembrane transportGO:00347621220.010
positive regulation of proteasomal protein catabolic processGO:190180030.010
purine nucleotide biosynthetic processGO:0006164830.010
cellular glucose homeostasisGO:0001678660.010
organic acid transportGO:00158491160.010
microtubule organizing center organizationGO:003102310.010
cellular response to carbohydrate stimulusGO:0071322720.010
triglyceride metabolic processGO:0006641210.010

Pdk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.232
inherited metabolic disorderDOID:65500.232
carbohydrate metabolic disorderDOID:297800.153
central nervous system diseaseDOID:33100.029
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
lysosomal storage diseaseDOID:321100.012
lipid storage diseaseDOID:945500.012
brain diseaseDOID:93600.012