Rattus norvegicus

0 known processes

Psap

prosaposin

(Aliases: SGP1A,SGP-1)

Psap biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
autophagic cell deathGO:004810240.286
catabolic processGO:00090563510.246
regulation of angiotensin metabolic processGO:006017730.233
single organism catabolic processGO:00447122830.198
cell growthGO:00160491040.175
cellular catabolic processGO:00442482950.161
organic substance catabolic processGO:19015753160.145
regulation of protein metabolic processGO:00512462890.140
positive regulation of multicellular organismal processGO:00512403870.135
response to cgmpGO:007030530.133
cellular component biogenesisGO:00440853680.132
organophosphate metabolic processGO:00196373700.129
negative regulation of nervous system developmentGO:0051961790.124
positive regulation of gene expressionGO:00106282440.113
cell type specific apoptotic processGO:00972851340.111
cellular response to external stimulusGO:00714961180.100
Rat
reproductive processGO:00224143720.100
cellular ketone metabolic processGO:0042180510.100
lipid metabolic processGO:00066292830.099
programmed cell deathGO:00125013920.097
oxoacid metabolic processGO:00434362900.097
negative regulation of cell developmentGO:0010721820.097
negative regulation of cell deathGO:00605482290.092
response to extracellular stimulusGO:00099913800.089
Rat
response to mechanical stimulusGO:00096121340.089
Rat
proteolysisGO:00065081750.089
regulation of cell differentiationGO:00455953200.087
carboxylic acid metabolic processGO:00197522890.085
angiotensin maturationGO:000200320.085
translationGO:0006412350.084
neuron projection developmentGO:00311752730.083
negative regulation of neuron differentiationGO:0045665620.082
growthGO:00400071650.081
multi organism reproductive processGO:00447032620.080
apoptotic processGO:00069153810.079
hormone metabolic processGO:0042445690.079
organic acid metabolic processGO:00060822920.079
blood circulationGO:00080151830.078
axon choice point recognitionGO:001619820.076
regulation of cell developmentGO:00602842630.075
regulation of blood pressureGO:0008217830.073
cell projection morphogenesisGO:00488581230.072
antigen processing and presentationGO:001988220.072
regulation of nervous system developmentGO:00519602640.071
regulation of hormone levelsGO:00108171870.070
cellular component assemblyGO:00226073600.066
regulation of growthGO:00400081050.062
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.062
ribose phosphate metabolic processGO:00196932350.062
positive regulation of nervous system developmentGO:00519621780.059
regulation of cellular amine metabolic processGO:003323880.058
multicellular organismal reproductive processGO:00486092330.058
response to nutrient levelsGO:00316673700.057
Rat
response to peptideGO:19016522920.057
regulation of multicellular organismal developmentGO:20000263760.057
protein phosphorylationGO:00064683450.057
developmental growthGO:00485891000.056
response to hexoseGO:00097461440.055
Rat
negative regulation of neurogenesisGO:0050768780.055
cellular lipid metabolic processGO:00442552080.055
retina development in camera type eyeGO:0060041270.055
negative regulation of developmental processGO:00510931250.054
regulation of neuron differentiationGO:00456642080.054
nucleobase containing small molecule metabolic processGO:00550863160.053
regulation of nucleic acid templated transcriptionGO:19035063800.053
carboxylic acid biosynthetic processGO:0046394830.052
regulation of cellular amino acid metabolic processGO:000652120.051
positive regulation of cell developmentGO:00107201760.050
reproductionGO:00000032450.050
endocytosisGO:0006897840.050
lipid biosynthetic processGO:00086101280.050
synaptic growth at neuromuscular junctionGO:005112410.050
single organism reproductive processGO:00447022970.049
sexual reproductionGO:00199531480.049
nucleotide metabolic processGO:00091172790.049
regulation of neurogenesisGO:00507672470.049
behaviorGO:00076102050.049
negative regulation of cell differentiationGO:0045596990.048
regulation of cellular component organizationGO:00511283680.047
regulation of cellular ketone metabolic processGO:0010565270.047
positive regulation of neurogenesisGO:00507691650.047
regulation of developmental growthGO:0048638450.047
negative regulation of multicellular organismal processGO:00512412030.046
neuromuscular processGO:005090520.045
response to campGO:0051591910.045
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988610.045
cellular calcium ion homeostasisGO:00068741600.045
multicellular organism reproductionGO:00325042330.045
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.045
response to organophosphorusGO:00466831020.043
ribonucleotide metabolic processGO:00092592310.042
cellular macromolecule catabolic processGO:0044265290.042
neuron differentiationGO:00301823680.042
organic hydroxy compound metabolic processGO:19016151150.041
cellular response to hormone stimulusGO:00328702470.041
alcohol metabolic processGO:0006066770.040
macromolecule catabolic processGO:0009057580.039
nitrogen compound transportGO:00717052290.039
glial cell differentiationGO:0010001650.038
homeostatic processGO:00425923310.038
rna biosynthetic processGO:00327743800.038
transcription from rna polymerase ii promoterGO:00063662520.037
transcription dna templatedGO:00063513770.037
response to oxygen levelsGO:00704822650.037
Rat
multicellular organismal catabolic processGO:004424320.037
single organism biosynthetic processGO:00447113420.037
adult locomotory behaviorGO:000834440.037
neuron developmentGO:00486662860.036
cell projection organizationGO:00300303020.036
regulation of apoptotic processGO:00429813350.036
axon cargo transportGO:000808810.035
protein maturationGO:0051604680.035
anatomical structure morphogenesisGO:00096532980.035
response to cytokineGO:00340972150.035
Rat
cellular chemical homeostasisGO:00550822470.034
positive regulation of rna metabolic processGO:00512542030.034
negative regulation of cellular component organizationGO:0051129830.034
regulation of cell growthGO:0001558850.034
positive regulation of developmental processGO:00510942830.033
response to glucoseGO:00097491360.033
Rat
response to starvationGO:0042594590.033
regulation of systemic arterial blood pressureGO:0003073300.033
steroid metabolic processGO:0008202730.033
response to external biotic stimulusGO:00432072210.033
Rat
protein catabolic processGO:0030163300.032
carbohydrate derivative catabolic processGO:19011361470.032
positive regulation of biosynthetic processGO:00098913190.032
cellular amide metabolic processGO:0043603440.031
regulation of signal transductionGO:00099663180.031
purine containing compound metabolic processGO:00725212530.031
cellular amine metabolic processGO:0044106380.031
amine metabolic processGO:0009308380.031
organelle assemblyGO:0070925220.031
nucleoside phosphate metabolic processGO:00067532830.030
proteolysis involved in cellular protein catabolic processGO:0051603190.030
cation transportGO:00068123820.030
multicellular organism growthGO:003526410.030
negative regulation of growthGO:0045926370.030
protein processingGO:0016485680.030
glycosyl compound catabolic processGO:19016581260.029
protein complex assemblyGO:00064612630.029
vesicle mediated transportGO:00161921810.029
head developmentGO:00603222470.029
protein complex subunit organizationGO:00718223020.029
purine nucleoside triphosphate metabolic processGO:00091441410.028
glycosyl compound metabolic processGO:19016571820.027
reproductive system developmentGO:00614581280.027
cellular ion homeostasisGO:00068731840.027
response to acid chemicalGO:00011012220.027
regulation of proteasomal protein catabolic processGO:006113640.027
cellular cation homeostasisGO:00300031800.027
cell morphogenesis involved in differentiationGO:00009041190.027
positive regulation of neuron differentiationGO:00456661260.027
neuron apoptotic processGO:0051402880.026
response to purine containing compoundGO:00140741260.026
regulation of cell projection organizationGO:00313441750.026
cellular response to endogenous stimulusGO:00714953770.026
developmental process involved in reproductionGO:00030061590.026
central nervous system developmentGO:00074173110.026
carbohydrate derivative metabolic processGO:19011353460.025
synaptic vesicle endocytosisGO:004848840.025
cellular response to nutrient levelsGO:0031669600.025
cellular response to extracellular stimulusGO:0031668730.025
defense responseGO:00069521940.025
tissue remodelingGO:0048771400.025
positive regulation of molecular functionGO:00440932300.025
purine ribonucleotide metabolic processGO:00091502270.025
response to oxidative stressGO:00069791860.025
Rat
enzyme linked receptor protein signaling pathwayGO:00071671160.024
positive regulation of cell differentiationGO:00455972170.024
regulation of protein phosphorylationGO:00019321830.023
purine nucleotide metabolic processGO:00061632290.023
antigen processing and presentation of peptide antigen via mhc class iiGO:000249510.023
regulation of rna biosynthetic processGO:20011413810.023
response to decreased oxygen levelsGO:00362932370.023
Rat
oxidation reduction processGO:00551143040.023
gamete generationGO:00072761240.023
antigen processing and presentation of exogenous antigenGO:001988410.023
organophosphate biosynthetic processGO:00904071430.023
negative regulation of neuron projection developmentGO:0010977460.023
positive regulation of protein metabolic processGO:00512471780.022
single organism carbohydrate metabolic processGO:00447231180.022
epithelial cell proliferationGO:0050673540.022
negative regulation of innate immune responseGO:004582440.022
single organism carbohydrate catabolic processGO:0044724400.022
response to hypoxiaGO:00016662310.022
Rat
epithelium developmentGO:0060429960.022
neuron deathGO:00709971270.022
response to carbohydrateGO:00097431830.022
Rat
ion homeostasisGO:00508012120.022
regulation of neuron projection developmentGO:00109751610.022
immune responseGO:00069551040.022
neuron projection extensionGO:1990138260.022
single organism intracellular transportGO:19025821660.022
positive regulation of cellular protein metabolic processGO:00322701670.022
axon midline choice point recognitionGO:001619920.022
regulation of transcription dna templatedGO:00063553740.022
positive regulation of programmed cell deathGO:00430681570.021
calcium ion transportGO:00068161310.021
muscle contractionGO:0006936880.021
metal ion transportGO:00300012890.021
autophagyGO:0006914190.021
glycogen metabolic processGO:0005977230.021
organic acid biosynthetic processGO:0016053830.021
regulation of protein modification processGO:00313991940.020
positive regulation of cellular biosynthetic processGO:00313282950.020
monocarboxylic acid metabolic processGO:00327871520.020
cell cycle phase transitionGO:0044770210.020
early endosome to late endosome transportGO:004502220.020
cell cycleGO:00070491010.020
chemical homeostasisGO:00488782920.020
cation homeostasisGO:00550801950.019
positive regulation of catalytic activityGO:00430851840.019
developmental programmed cell deathGO:001062320.019
regulation of programmed cell deathGO:00430673410.019
cellular homeostasisGO:00197252520.019
nucleoside triphosphate catabolic processGO:00091431230.019
positive regulation of cell projection organizationGO:00313461110.019
cellular response to stressGO:00335542690.019
Rat
positive regulation of cellular amine metabolic processGO:003324030.019
cellular amino acid biosynthetic processGO:0008652320.019
regulation of cell sizeGO:0008361370.019
antigen processing and presentation of exogenous peptide antigenGO:000247810.019
reproductive behaviorGO:0019098100.019
positive regulation of cell cycle g2 m phase transitionGO:190275110.019
regulation of system processGO:00440572080.018
respiratory system developmentGO:0060541450.018
cell part morphogenesisGO:00329901230.018
organophosphate catabolic processGO:00464341480.018
positive regulation of neuron projection developmentGO:0010976990.018
cellular metal ion homeostasisGO:00068751720.018
regulation of cell cycle g2 m phase transitionGO:190274940.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
cellular nitrogen compound catabolic processGO:00442701630.018
organelle organizationGO:00069962660.018
regulation of phosphorus metabolic processGO:00511743490.018
organonitrogen compound biosynthetic processGO:19015661670.018
wound healingGO:00420601220.018
transmembrane transportGO:00550854120.018
negative regulation of natural killer cell mediated immunityGO:000271640.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
regulation of g2 m transition of mitotic cell cycleGO:001038940.017
positive regulation of rna biosynthetic processGO:19026801970.017
regulation of protein kinase activityGO:00458591050.017
cellular protein catabolic processGO:0044257190.017
neuron projection morphogenesisGO:00488121220.017
gliogenesisGO:0042063930.017
nucleotide biosynthetic processGO:0009165980.017
cellular amino acid metabolic processGO:00065201070.017
protein complex biogenesisGO:00702712630.017
organonitrogen compound catabolic processGO:19015651790.017
response to amineGO:0014075460.017
intracellular transportGO:00469071850.017
mitotic spindle organizationGO:000705220.017
nucleobase containing compound catabolic processGO:00346551520.017
regenerationGO:00310991630.017
response to cadmium ionGO:0046686350.016
regulation of fat cell differentiationGO:004559830.016
cell morphogenesisGO:00009021420.016
response to amino acidGO:0043200750.016
rna metabolic processGO:00160704060.016
posttranscriptional regulation of gene expressionGO:0010608370.016
cellular response to growth factor stimulusGO:00713631620.016
reproductive structure developmentGO:00486081280.016
regulation of cell proliferationGO:00421273590.016
regulation of transferase activityGO:00513381230.016
peptide metabolic processGO:0006518320.016
positive regulation of growthGO:0045927550.016
collagen catabolic processGO:003057420.016
mrna 3 end processingGO:003112410.016
axonogenesisGO:0007409710.016
synaptic transmissionGO:00072682350.016
organelle inheritanceGO:004830820.015
purine nucleoside metabolic processGO:00422781690.015
carbohydrate metabolic processGO:00059751300.015
dendrite developmentGO:0016358720.015
calcium ion homeostasisGO:00550741620.015
peptidyl amino acid modificationGO:00181931260.015
positive regulation of cell proliferationGO:00082842490.015
camera type eye developmentGO:0043010480.015
gastrulationGO:000736920.015
regulation of ion transportGO:00432692450.015
regulation of kinase activityGO:00435491170.015
regulation of phosphorylationGO:00423252480.015
purine containing compound catabolic processGO:00725231380.015
nucleotide catabolic processGO:00091661390.015
response to radiationGO:00093141370.015
multi multicellular organism processGO:00447061380.015
endocrine processGO:0050886320.015
synapse organizationGO:0050808460.015
positive regulation of g2 m transition of mitotic cell cycleGO:001097110.014
regulation of transcription regulatory region dna bindingGO:200067740.014
muscle system processGO:00030121150.014
female pregnancyGO:00075651220.014
purine nucleoside catabolic processGO:00061521240.014
positive regulation of cellular component organizationGO:00511302000.014
sterol metabolic processGO:0016125180.014
chromatin organizationGO:0006325340.014
striated muscle tissue developmentGO:0014706580.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
developmental inductionGO:003112820.014
negative regulation of response to stimulusGO:00485851550.014
ribonucleotide biosynthetic processGO:0009260850.014
protection from natural killer cell mediated cytotoxicityGO:004227020.014
response to glucocorticoidGO:00513842230.014
Rat
cellular response to organonitrogen compoundGO:00714171970.014
agingGO:00075682410.014
axon developmentGO:0061564960.014
cellular response to drugGO:0035690300.013
nucleoside catabolic processGO:00091641260.013
purine ribonucleoside catabolic processGO:00461301240.013
negative regulation of cell cycle phase transitionGO:190198840.013
neurological system processGO:00508772190.013
regulation of axonogenesisGO:0050770370.013
positive regulation of hydrolase activityGO:0051345860.013
nucleoside phosphate biosynthetic processGO:19012931020.013
metal ion homeostasisGO:00550651860.013
purine nucleoside triphosphate catabolic processGO:00091461220.013
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:000250410.013
sex differentiationGO:00075481130.013
negative regulation of apoptotic processGO:00430661810.013
secretion by cellGO:00329402480.013
response to light stimulusGO:0009416520.013
transmission of nerve impulseGO:0019226420.013
male mating behaviorGO:006017930.013
aromatic compound catabolic processGO:00194391680.013
multicellular organismal homeostasisGO:0048871490.013
regulation of rna metabolic processGO:00512523910.013
ionotropic glutamate receptor signaling pathwayGO:0035235340.013
response to biotic stimulusGO:00096072260.013
Rat
regulation of blood circulationGO:19035221100.013
response to growth factorGO:00708481890.013
Rat
nucleoside metabolic processGO:00091161790.013
polysaccharide metabolic processGO:0005976250.013
regulation of organelle organizationGO:0033043800.013
germ cell migrationGO:000835410.013
synaptic vesicle localizationGO:0097479240.013
autophagic vacuole assemblyGO:000004540.013
cellular response to mechanical stimulusGO:0071260480.013
Rat
epithelial cell differentiationGO:0030855710.012
membrane organizationGO:0061024940.012
insulin like growth factor receptor signaling pathwayGO:004800930.012
regulation of immunoglobulin productionGO:000263740.012
glutamine family amino acid biosynthetic processGO:000908420.012
purine ribonucleotide biosynthetic processGO:0009152810.012
purine nucleotide biosynthetic processGO:0006164830.012
positive regulation of transcription dna templatedGO:00458931970.012
bmp signaling pathwayGO:003050940.012
spermatogenesisGO:0007283990.012
positive regulation of nucleic acid templated transcriptionGO:19035081970.012
response to nutrientGO:00075842480.012
Rat
macromolecular complex subunit organizationGO:00439333390.012
regulation of blood vessel sizeGO:0050880890.012
salivary gland developmentGO:000743130.012
regulation of molecular functionGO:00650093980.012
biological adhesionGO:00226101100.012
cellular component morphogenesisGO:00329891550.012
positive regulation of blood circulationGO:1903524650.012
positive regulation of apoptotic processGO:00430651540.012
epidermal growth factor receptor signaling pathwayGO:0007173230.012
dephosphorylationGO:0016311980.012
small molecule biosynthetic processGO:00442831240.012
cellular response to oxygen containing compoundGO:19017013860.012
Rat
intracellular signal transductionGO:00355563140.012
positive regulation of cell growthGO:0030307440.012
positive regulation of nucleobase containing compound metabolic processGO:00459353190.012
carbohydrate biosynthetic processGO:0016051420.012
positive regulation of cell deathGO:00109421840.011
mapk cascadeGO:00001651400.011
response to insulinGO:00328681330.011
chemotaxisGO:0006935660.011
single organism organelle organizationGO:19025891800.011
regulation of response to stressGO:00801341260.011
negative regulation of protein phosphorylationGO:0001933440.011
secretionGO:00469033070.011
coagulationGO:0050817280.011
peptidyl serine modificationGO:0018209340.011
multicellular organismal signalingGO:0035637440.011
protein homooligomerizationGO:0051260910.011
chemosensory behaviorGO:000763520.011
anion transmembrane transportGO:0098656770.011
glucose metabolic processGO:0006006520.011
regulation of protein complex assemblyGO:0043254330.011
protein oligomerizationGO:00512591910.011
positive regulation of muscle contractionGO:0045933220.011
cellular component movementGO:00069282480.011
response to vitaminGO:00332731310.011
Rat
cellular protein localizationGO:00346131220.011
organ inductionGO:000175910.011
regulation of organ formationGO:000315620.011
male gamete generationGO:0048232990.011
regulation of muscle system processGO:0090257790.011
protein transportGO:00150311320.010
peptidyl tyrosine modificationGO:0018212720.010
negative regulation of peptidase activityGO:0010466380.010
cellular response to cytokine stimulusGO:00713451270.010
ras protein signal transductionGO:0007265290.010
regulation of peptidase activityGO:0052547550.010
hormone secretionGO:00468791150.010
response to woundingGO:00096112540.010

Psap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
lysosomal storage diseaseDOID:321100.381
lipid storage diseaseDOID:945500.381
disease of metabolismDOID:001466700.381
inherited metabolic disorderDOID:65500.381
nervous system diseaseDOID:86300.061
disease of anatomical entityDOID:700.061
central nervous system diseaseDOID:33100.029
combined t cell and b cell immunodeficiencyDOID:62800.028
immune system diseaseDOID:291400.028
severe combined immunodeficiencyDOID:62700.028
primary immunodeficiency diseaseDOID:61200.028
musculoskeletal system diseaseDOID:1700.017
acquired metabolic diseaseDOID:006015800.014
bone diseaseDOID:008000100.012
connective tissue diseaseDOID:6500.012