Rattus norvegicus

76 known processes

Kcnj2

potassium inwardly-rectifying channel, subfamily J, member 2

(Aliases: Kir2.1)

Kcnj2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.361
oxoacid metabolic processGO:00434362900.272
organic acid metabolic processGO:00060822920.225
monocarboxylic acid metabolic processGO:00327871520.195
cellular chemical homeostasisGO:00550822470.125
Rat
single organism biosynthetic processGO:00447113420.119
cellular homeostasisGO:00197252520.110
Rat
regulation of cell differentiationGO:00455953200.102
reproductive processGO:00224143720.102
homeostatic processGO:00425923310.090
Rat
single organism carbohydrate metabolic processGO:00447231180.082
cellular response to oxygen containing compoundGO:19017013860.081
Rat
response to peptideGO:19016522920.077
negative regulation of macromolecule metabolic processGO:00106052600.077
regulation of molecular functionGO:00650093980.075
Rat
cellular amino acid metabolic processGO:00065201070.074
dephosphorylationGO:0016311980.070
immune system processGO:00023762040.070
signal releaseGO:00230611450.069
cellular response to endogenous stimulusGO:00714953770.068
Rat
carbohydrate metabolic processGO:00059751300.062
response to nutrient levelsGO:00316673700.055
cell cell signalingGO:00072673350.053
organophosphate metabolic processGO:00196373700.053
response to inorganic substanceGO:00100353770.052
positive regulation of immune system processGO:0002684900.051
ion homeostasisGO:00508012120.050
cellular response to organonitrogen compoundGO:00714171970.050
Rat
central nervous system developmentGO:00074173110.050
regulation of protein metabolic processGO:00512462890.049
positive regulation of cell projection organizationGO:00313461110.049
regulation of nervous system developmentGO:00519602640.049
cellular ketone metabolic processGO:0042180510.048
response to organophosphorusGO:00466831020.047
negative regulation of metabolic processGO:00098923310.047
glucose homeostasisGO:0042593750.047
Rat
cellular ion homeostasisGO:00068731840.047
regulation of cellular protein metabolic processGO:00322682670.047
positive regulation of cell differentiationGO:00455972170.044
single organism behaviorGO:00447081300.043
Fly
protein phosphorylationGO:00064683450.043
chemical homeostasisGO:00488782920.042
Rat
positive regulation of cellular protein metabolic processGO:00322701670.042
oxidation reduction processGO:00551143040.042
negative regulation of response to stimulusGO:00485851550.042
Fly
regulation of neuron projection developmentGO:00109751610.040
transcription from rna polymerase ii promoterGO:00063662520.040
lipid metabolic processGO:00066292830.040
positive regulation of neuron projection developmentGO:0010976990.039
regulation of cellular component organizationGO:00511283680.038
regulation of immune system processGO:00026821230.038
regulation of transcription dna templatedGO:00063553740.038
positive regulation of neurogenesisGO:00507691650.036
regulation of cellular ketone metabolic processGO:0010565270.035
agingGO:00075682410.034
regulation of cell projection organizationGO:00313441750.033
cellular response to stressGO:00335542690.033
response to fungicideGO:0060992200.033
divalent metal ion transportGO:00708381320.032
Mouse
carbohydrate derivative metabolic processGO:19011353460.031
single organism reproductive processGO:00447022970.031
response to decreased oxygen levelsGO:00362932370.031
positive regulation of nervous system developmentGO:00519621780.031
fatty acid metabolic processGO:0006631990.030
cellular response to peptideGO:19016531330.030
biological adhesionGO:00226101100.030
response to extracellular stimulusGO:00099913800.030
regulation of locomotionGO:00400121480.030
response to purine containing compoundGO:00140741260.029
mesoderm developmentGO:000749820.029
negative regulation of protein metabolic processGO:00512481140.029
negative regulation of cell communicationGO:00106481580.029
Fly
positive regulation of catalytic activityGO:00430851840.028
cellular response to lipidGO:00713962010.028
gland developmentGO:00487321550.028
response to monosaccharideGO:00342841590.027
Rat
negative regulation of multicellular organismal processGO:00512412030.027
organophosphate biosynthetic processGO:00904071430.027
cellular component morphogenesisGO:00329891550.026
Fly
regulation of metal ion transportGO:00109591180.026
negative regulation of transportGO:00510511360.026
positive regulation of multicellular organismal processGO:00512403870.026
inorganic ion transmembrane transportGO:00986602290.026
regulation of peptide transportGO:0090087870.026
cognitionGO:0050890920.026
metal ion transportGO:00300012890.025
positive regulation of biosynthetic processGO:00098913190.025
defense responseGO:00069521940.025
single organism intracellular transportGO:19025821660.025
hepaticobiliary system developmentGO:0061008900.025
intracellular signal transductionGO:00355563140.025
multi organism reproductive processGO:00447032620.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.025
cellular metal ion homeostasisGO:00068751720.025
regulation of protein modification processGO:00313991940.025
cellular response to nitrogen compoundGO:19016992100.025
Rat
response to carbohydrateGO:00097431830.025
Rat
response to vitaminGO:00332731310.024
response to cytokineGO:00340972150.024
Rat
protein localizationGO:00081041910.024
positive regulation of nitrogen compound metabolic processGO:00511733340.024
regulation of system processGO:00440572080.024
positive regulation of cell developmentGO:00107201760.024
cellular response to reactive oxygen speciesGO:0034614550.024
regulation of cellular amine metabolic processGO:003323880.024
regulation of multicellular organismal developmentGO:20000263760.023
brain developmentGO:00074202470.023
synaptic transmissionGO:00072682350.023
positive regulation of protein phosphorylationGO:00019341350.023
response to oxygen levelsGO:00704822650.022
response to growth factorGO:00708481890.022
steroid metabolic processGO:0008202730.022
lipid oxidationGO:0034440300.022
divalent inorganic cation transportGO:00725111340.021
Mouse
amine metabolic processGO:0009308380.021
immune responseGO:00069551040.021
organic hydroxy compound metabolic processGO:19016151150.021
liver developmentGO:0001889900.021
positive regulation of developmental processGO:00510942830.021
negative regulation of gene expressionGO:00106291990.021
rna biosynthetic processGO:00327743800.021
positive regulation of neuron differentiationGO:00456661260.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
reproductionGO:00000032450.021
regulation of catalytic activityGO:00507903040.021
regulation of neuron differentiationGO:00456642080.021
response to peptide hormoneGO:00434342780.020
positive regulation of programmed cell deathGO:00430681570.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
sequestering of metal ionGO:005123890.020
positive regulation of cell proliferationGO:00082842490.020
regulation of phosphorus metabolic processGO:00511743490.020
regulation of calcium ion transportGO:0051924770.020
response to glucoseGO:00097491360.020
Rat
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.020
cellular response to lipopolysaccharideGO:0071222550.020
positive regulation of phosphorus metabolic processGO:00105622620.020
negative regulation of cell differentiationGO:0045596990.019
regulation of blood pressureGO:0008217830.019
response to reactive oxygen speciesGO:00003021200.019
response to nutrientGO:00075842480.019
chemosensory behaviorGO:000763520.019
behaviorGO:00076102050.019
Fly
regulation of insulin secretionGO:0050796650.019
regulation of cell developmentGO:00602842630.019
regulation of homeostatic processGO:00328441010.019
positive regulation of cellular amine metabolic processGO:003324030.019
small molecule biosynthetic processGO:00442831240.019
response to woundingGO:00096112540.018
intracellular transportGO:00469071850.018
hemopoiesisGO:0030097340.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
mesoderm morphogenesisGO:004833210.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
negative regulation of cellular metabolic processGO:00313242810.018
multicellular organismal reproductive processGO:00486092330.017
developmental process involved in reproductionGO:00030061590.017
embryonic pattern specificationGO:000988010.017
cellular calcium ion homeostasisGO:00068741600.017
leukocyte differentiationGO:0002521300.017
eye morphogenesisGO:004859240.017
female pregnancyGO:00075651220.017
head developmentGO:00603222470.017
regulation of cell growthGO:0001558850.017
development of primary sexual characteristicsGO:00451371070.017
organic substance catabolic processGO:19015753160.016
cellular lipid metabolic processGO:00442552080.016
rna metabolic processGO:00160704060.016
regulation of rna metabolic processGO:00512523910.016
fatty acid oxidationGO:0019395290.016
programmed cell deathGO:00125013920.016
insulin secretionGO:0030073690.016
positive regulation of apoptotic processGO:00430651540.016
response to toxic substanceGO:00096361330.016
calcium ion homeostasisGO:00550741620.016
positive regulation of mapk cascadeGO:0043410920.016
cellular amine metabolic processGO:0044106380.016
nucleoside metabolic processGO:00091161790.016
negative regulation of cell deathGO:00605482290.016
response to oxidative stressGO:00069791860.016
tissue developmentGO:00098882520.016
sequestering of calcium ionGO:005120880.016
regulation of response to stressGO:00801341260.016
neuron differentiationGO:00301823680.016
Fly
insulin like growth factor receptor signaling pathwayGO:004800930.016
negative regulation of rna biosynthetic processGO:19026791180.015
positive regulation of cellular biosynthetic processGO:00313282950.015
metal ion homeostasisGO:00550651860.015
cellular response to cytokine stimulusGO:00713451270.015
Rat
locomotionGO:00400112370.015
sex differentiationGO:00075481130.015
negative regulation of programmed cell deathGO:00430691830.015
response to corticosteroidGO:00319602350.015
multicellular organismal homeostasisGO:0048871490.015
neuron developmentGO:00486662860.015
Fly
peptidyl amino acid modificationGO:00181931260.015
activation of cysteine type endopeptidase activityGO:009720240.015
dicarboxylic acid metabolic processGO:0043648420.014
response to hexoseGO:00097461440.014
Rat
adult locomotory behaviorGO:000834440.014
sexual reproductionGO:00199531480.014
cellular component movementGO:00069282480.014
regulation of rna biosynthetic processGO:20011413810.014
positive regulation of protein metabolic processGO:00512471780.014
regulation of cellular amino acid metabolic processGO:000652120.014
lipid biosynthetic processGO:00086101280.014
regulation of hydrolase activityGO:00513361430.014
cellular response to tumor necrosis factorGO:0071356460.014
Rat
positive regulation of phosphorylationGO:00423271770.014
erythrocyte differentiationGO:003021810.014
regulation of protein phosphorylationGO:00019321830.014
regulation of transferase activityGO:00513381230.014
cellular cation homeostasisGO:00300031800.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
response to activityGO:0014823730.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
purine containing compound metabolic processGO:00725212530.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
positive regulation of cellular component organizationGO:00511302000.013
nucleoside phosphate metabolic processGO:00067532830.013
cellular response to oxidative stressGO:0034599760.013
salivary gland developmentGO:000743130.013
regulation of potassium ion transportGO:0043266290.013
response to external biotic stimulusGO:00432072210.013
regulation of apoptotic processGO:00429813350.013
regulation of neurogenesisGO:00507672470.013
response to follicle stimulating hormoneGO:0032354180.013
gamete generationGO:00072761240.013
immunoglobulin secretionGO:004830510.013
apoptotic processGO:00069153810.013
regulation of transmembrane transportGO:00347621220.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
lipid modificationGO:0030258520.013
muscle tissue developmentGO:0060537580.013
peptide transportGO:0015833970.013
regulation of sodium ion transmembrane transporter activityGO:200064940.013
cellular response to interleukin 1GO:0071347370.013
cellular response to metal ionGO:0071248550.013
carbohydrate biosynthetic processGO:0016051420.013
cytokine mediated signaling pathwayGO:0019221430.013
regulation of peptide hormone secretionGO:0090276800.013
cellular response to inorganic substanceGO:0071241650.013
cation homeostasisGO:00550801950.013
negative regulation of secretion by cellGO:1903531720.012
regulation of nucleic acid templated transcriptionGO:19035063800.012
male gonad developmentGO:0008584590.012
positive regulation of gene expressionGO:00106282440.012
response to radiationGO:00093141370.012
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633930.012
negative regulation of secretionGO:0051048820.012
divalent inorganic cation homeostasisGO:00725071650.012
cell migrationGO:00164771970.012
glucose metabolic processGO:0006006520.012
nucleobase containing small molecule metabolic processGO:00550863160.012
neurological system processGO:00508772190.012
regulation of signal transductionGO:00099663180.012
Fly
calcium ion transportGO:00068161310.012
retina morphogenesis in camera type eyeGO:006004210.012
positive regulation of transferase activityGO:0051347810.012
t cell homeostasisGO:004302920.012
response to amineGO:0014075460.012
platelet aggregationGO:007052740.012
regulation of response to woundingGO:1903034690.012
sensory organ developmentGO:0007423740.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
localization of cellGO:00516742020.011
positive regulation of cell deathGO:00109421840.011
myeloid cell differentiationGO:0030099220.011
immune system developmentGO:0002520410.011
organonitrogen compound biosynthetic processGO:19015661670.011
positive regulation of purine nucleotide biosynthetic processGO:1900373360.011
regulation of kinase activityGO:00435491170.011
carboxylic acid catabolic processGO:0046395490.011
regulation of intracellular signal transductionGO:19025312180.011
neuron deathGO:00709971270.011
negative regulation of molecular functionGO:00440921330.011
secretion by cellGO:00329402480.011
regulation of protein serine threonine kinase activityGO:0071900640.011
response to increased oxygen levelsGO:0036296450.011
positive regulation of immune responseGO:0050778420.011
macromolecule localizationGO:00330362520.011
negative regulation of cellular component organizationGO:0051129830.011
olfactory behaviorGO:004204820.011
cellular response to hexose stimulusGO:0071331650.011
Rat
nucleic acid templated transcriptionGO:00976593790.011
striated muscle tissue developmentGO:0014706580.011
tissue remodelingGO:0048771400.011
organic acid catabolic processGO:0016054490.011
gonad developmentGO:00084061040.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
cellular response to growth factor stimulusGO:00713631620.010
cell adhesionGO:00071551100.010
regulation of ion transportGO:00432692450.010
regulation of immune responseGO:0050776550.010
catabolic processGO:00090563510.010
gastrulationGO:000736920.010
negative regulation of macromolecule biosynthetic processGO:00105581480.010
purine nucleotide metabolic processGO:00061632290.010
lymphocyte activation involved in immune responseGO:000228530.010
carbohydrate homeostasisGO:0033500750.010
Rat
negative regulation of signal transductionGO:0009968830.010
Fly
organ morphogenesisGO:0009887750.010
regulation of hormone secretionGO:00468831060.010
negative regulation of cellular protein metabolic processGO:00322691060.010
regenerationGO:00310991630.010
positive regulation of molecular functionGO:00440932300.010
Rat
cellular component assemblyGO:00226073600.010
Human
sensory perceptionGO:00076001010.010
positive regulation of protein modification processGO:00314011420.010
sodium ion transmembrane transportGO:0035725670.010
b cell differentiationGO:003018320.010

Kcnj2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
Human
disease of metabolismDOID:001466700.017
central nervous system diseaseDOID:33100.017
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
inherited metabolic disorderDOID:65500.011
kidney diseaseDOID:55700.010
urinary system diseaseDOID:1800.010