IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Pdzk1

PDZ domain containing 1

(Aliases: Clamp)

Entrez: 65144
RGD: 70924
UniProtKB: Q9JJ40

Process Predictions
Disease Predictions

Pdzk1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
choline transport	GO:0015871	4	0.278
organic acid metabolic process	GO:0006082	292	0.270
transmembrane transport	GO:0055085	412	0.175
response to metal ion	GO:0010038	253	0.166
cation transport	GO:0006812	382	0.133
response to inorganic substance	GO:0010035	377	0.132
carboxylic acid metabolic process	GO:0019752	289	0.131
cellular response to nitrogen compound	GO:1901699	210	0.116
aromatic amino acid family catabolic process	GO:0009074	7	0.113
oxoacid metabolic process	GO:0043436	290	0.110
organic anion transport	GO:0015711	132	0.110
response to peptide	GO:1901652	292	0.100
protein complex assembly	GO:0006461	263	0.098
small molecule biosynthetic process	GO:0044283	124	0.095
aromatic amino acid family metabolic process	GO:0009072	9	0.093
anion transport	GO:0006820	178	0.090
nitrogen compound transport	GO:0071705	229	0.089
cellular amino acid metabolic process	GO:0006520	107	0.088
cellular response to endogenous stimulus	GO:0071495	377	0.087
alpha amino acid metabolic process	GO:1901605	71	0.087
response to corticosteroid	GO:0031960	235	0.084
hormone metabolic process	GO:0042445	69	0.083
neuron differentiation	GO:0030182	368	0.082
cellular response to peptide	GO:1901653	133	0.080
tripeptide transport	GO:0042939	2	0.077
single organism biosynthetic process	GO:0044711	342	0.077
ion transmembrane transport	GO:0034220	365	0.075
protein complex subunit organization	GO:0071822	302	0.075
cellular component biogenesis	GO:0044085	368	0.075
protein oligomerization	GO:0051259	191	0.075
cellular response to oxygen containing compound	GO:1901701	386	0.075
response to glucocorticoid	GO:0051384	223	0.074
establishment or maintenance of transmembrane electrochemical gradient	GO:0010248	1	0.071
organophosphate metabolic process	GO:0019637	370	0.068
macromolecular complex subunit organization	GO:0043933	339	0.067
response to nutrient levels	GO:0031667	370	0.065
carboxylic acid transport	GO:0046942	115	0.065
coenzyme metabolic process	GO:0006732	86	0.065
nucleobase containing small molecule metabolic process	GO:0055086	316	0.064
single organism catabolic process	GO:0044712	283	0.063
cellular component assembly	GO:0022607	360	0.063
protein complex biogenesis	GO:0070271	263	0.061
homeostatic process	GO:0042592	331	0.060
catabolic process	GO:0009056	351	0.060
multicellular organism reproduction	GO:0032504	233	0.058
drug transmembrane transport	GO:0006855	13	0.058
regulation of neuron differentiation	GO:0045664	208	0.057
cation transmembrane transport	GO:0098655	263	0.057
oligopeptide transport	GO:0006857	4	0.057
head development	GO:0060322	247	0.057
cellular hormone metabolic process	GO:0034754	49	0.056
response to acid chemical	GO:0001101	222	0.055
organic hydroxy compound metabolic process	GO:1901615	115	0.055
indolalkylamine metabolic process	GO:0006586	5	0.053
cellular catabolic process	GO:0044248	295	0.053
central nervous system development	GO:0007417	311	0.053
sodium independent organic anion transport	GO:0043252	2	0.053
response to extracellular stimulus	GO:0009991	380	0.051
antibiotic transport	GO:0042891	2	0.050
macromolecular complex assembly	GO:0065003	273	0.050
organic substance catabolic process	GO:1901575	316	0.050
cellular response to stress	GO:0033554	269	0.049
cellular response to steroid hormone stimulus	GO:0071383	93	0.049
macromolecule localization	GO:0033036	252	0.047
aging	GO:0007568	241	0.047
glutathione transport	GO:0034635	2	0.044
reproductive process	GO:0022414	372	0.044
response to peptide hormone	GO:0043434	278	0.044
hormone transport	GO:0009914	121	0.044
oxidation reduction process	GO:0055114	304	0.044
circulatory system process	GO:0003013	183	0.044
single organism organelle organization	GO:1902589	180	0.043
regulation of cell development	GO:0060284	263	0.043
response to toxic substance	GO:0009636	133	0.042
brain development	GO:0007420	247	0.041
positive regulation of neuron projection development	GO:0010976	99	0.040
cellular response to hormone stimulus	GO:0032870	247	0.040
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.039
cofactor metabolic process	GO:0051186	95	0.039
response to estradiol	GO:0032355	164	0.038
regulation of multicellular organismal development	GO:2000026	376	0.038
divalent inorganic cation transport	GO:0072511	134	0.038
response to carbohydrate	GO:0009743	183	0.037
neuron development	GO:0048666	286	0.037
purine containing compound metabolic process	GO:0072521	253	0.037
organonitrogen compound catabolic process	GO:1901565	179	0.036
regulation of neuron projection development	GO:0010975	161	0.036
cytoskeleton organization	GO:0007010	111	0.035
response to growth factor	GO:0070848	189	0.035
synaptic transmission	GO:0007268	235	0.035
reproduction	GO:0000003	245	0.035
response to vitamin	GO:0033273	131	0.034
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.034
cyclic purine nucleotide metabolic process	GO:0052652	62	0.034
dicarboxylic acid metabolic process	GO:0043648	42	0.034
response to oxidative stress	GO:0006979	186	0.034
cellular homeostasis	GO:0019725	252	0.034
response to ethanol	GO:0045471	162	0.033
cellular response to organonitrogen compound	GO:0071417	197	0.033
response to estrogen	GO:0043627	232	0.033
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.032
amine metabolic process	GO:0009308	38	0.032
response to alkaloid	GO:0043279	132	0.031
rna metabolic process	GO:0016070	406	0.031
neurotransmitter transport	GO:0006836	42	0.031
regulation of ion transport	GO:0043269	245	0.030
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.030
single organism behavior	GO:0044708	130	0.030
cellular response to peptide hormone stimulus	GO:0071375	120	0.030
cellular response to glucocorticoid stimulus	GO:0071385	68	0.030
memory	GO:0007613	54	0.030
response to monosaccharide	GO:0034284	159	0.030
organophosphate biosynthetic process	GO:0090407	143	0.029
sorbitol biosynthetic process	GO:0006061	1	0.029
regulation of nervous system development	GO:0051960	264	0.029
positive regulation of nucleotide metabolic process	GO:0045981	91	0.029
organelle organization	GO:0006996	266	0.029
positive regulation of cellular biosynthetic process	GO:0031328	295	0.029
inorganic ion transmembrane transport	GO:0098660	229	0.029
positive regulation of neuron differentiation	GO:0045666	126	0.028
growth	GO:0040007	165	0.028
regulation of cellular component organization	GO:0051128	368	0.028
alcohol metabolic process	GO:0006066	77	0.028
multi organism reproductive process	GO:0044703	262	0.028
modified amino acid transport	GO:0072337	12	0.028
rhythmic process	GO:0048511	156	0.028
organic hydroxy compound transport	GO:0015850	77	0.028
positive regulation of transcription dna templated	GO:0045893	197	0.027
protein localization	GO:0008104	191	0.027
secretion	GO:0046903	307	0.027
actin filament based process	GO:0030029	86	0.027
negative regulation of signaling	GO:0023057	157	0.027
regulation of programmed cell death	GO:0043067	341	0.027
cellular response to organic cyclic compound	GO:0071407	202	0.027
cellular macromolecule localization	GO:0070727	122	0.027
neurological system process	GO:0050877	219	0.026
response to glucose	GO:0009749	136	0.026
regulation of cell differentiation	GO:0045595	320	0.026
nucleoside phosphate biosynthetic process	GO:1901293	102	0.026
cellular lipid metabolic process	GO:0044255	208	0.026
nucleoside phosphate metabolic process	GO:0006753	283	0.025
regulation of hormone levels	GO:0010817	187	0.025
protein homooligomerization	GO:0051260	91	0.025
sulfur compound transport	GO:0072348	8	0.025
toxin transport	GO:1901998	3	0.025
metal ion transport	GO:0030001	289	0.025
monocarboxylic acid transport	GO:0015718	52	0.024
regulation of nucleic acid templated transcription	GO:1903506	380	0.024
hormone mediated signaling pathway	GO:0009755	23	0.024
purine ribonucleotide metabolic process	GO:0009150	227	0.024
negative regulation of gene expression	GO:0010629	199	0.024
regulation of cell projection organization	GO:0031344	175	0.024
positive regulation of ion transport	GO:0043270	94	0.024
neuron projection development	GO:0031175	273	0.024
drug transport	GO:0015893	18	0.023
cellular amine metabolic process	GO:0044106	38	0.023
regulation of nucleotide metabolic process	GO:0006140	117	0.023
terpenoid metabolic process	GO:0006721	37	0.023
isoprenoid metabolic process	GO:0006720	45	0.023
multicellular organismal reproductive process	GO:0048609	233	0.023
single organism nuclear import	GO:1902593	35	0.023
carbohydrate derivative metabolic process	GO:1901135	346	0.022
cellular modified amino acid metabolic process	GO:0006575	61	0.022
organic cyclic compound catabolic process	GO:1901361	175	0.022
organonitrogen compound biosynthetic process	GO:1901566	167	0.022
positive regulation of neurogenesis	GO:0050769	165	0.022
response to nutrient	GO:0007584	248	0.022
purine nucleotide metabolic process	GO:0006163	229	0.022
nicotinamide nucleotide metabolic process	GO:0046496	28	0.022
regulation of blood volume by renal aldosterone	GO:0002017	1	0.022
alpha amino acid biosynthetic process	GO:1901607	23	0.022
sulfur compound metabolic process	GO:0006790	70	0.022
response to molecule of fungal origin	GO:0002238	3	0.022
cellular chemical homeostasis	GO:0055082	247	0.021
rna biosynthetic process	GO:0032774	380	0.021
exploration behavior	GO:0035640	1	0.021
negative regulation of macromolecule metabolic process	GO:0010605	260	0.021
cell projection organization	GO:0030030	302	0.021
positive regulation of rna biosynthetic process	GO:1902680	197	0.020
cellular ketone metabolic process	GO:0042180	51	0.020
lipid transport	GO:0006869	61	0.020
response to blue light	GO:0009637	1	0.020
negative regulation of transport	GO:0051051	136	0.020
response to light stimulus	GO:0009416	52	0.020
negative regulation of metabolic process	GO:0009892	331	0.019
regulation of response to stress	GO:0080134	126	0.019
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.019
locomotory exploration behavior	GO:0035641	1	0.019
response to wounding	GO:0009611	254	0.019
actin cytoskeleton organization	GO:0030036	73	0.019
carboxylic acid catabolic process	GO:0046395	49	0.019
positive regulation of transport	GO:0051050	245	0.018
negative regulation of cell communication	GO:0010648	158	0.018
cell cell signaling	GO:0007267	335	0.018
epinephrine transport	GO:0048241	7	0.018
intracellular transport	GO:0046907	185	0.018
ribonucleotide biosynthetic process	GO:0009260	85	0.018
regulation of rna biosynthetic process	GO:2001141	381	0.018
androgen metabolic process	GO:0008209	14	0.018
cellular response to hexose stimulus	GO:0071331	65	0.018
positive regulation of cellular component organization	GO:0051130	200	0.018
positive regulation of rna metabolic process	GO:0051254	203	0.018
defecation	GO:0030421	1	0.018
reactive oxygen species metabolic process	GO:0072593	37	0.017
response to herbicide	GO:0009635	16	0.017
lipid localization	GO:0010876	62	0.017
response to bacterium	GO:0009617	200	0.017
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.017
aromatic compound catabolic process	GO:0019439	168	0.017
cellular response to corticosteroid stimulus	GO:0071384	69	0.017
nucleotide biosynthetic process	GO:0009165	98	0.017
cellular metal ion homeostasis	GO:0006875	172	0.017
regulation of cellular component biogenesis	GO:0044087	86	0.017
negative regulation of innate immune response	GO:0045824	4	0.017
cellular response to fluid shear stress	GO:0071498	4	0.017
retinal metabolic process	GO:0042574	3	0.017
response to hexose	GO:0009746	144	0.017
regulation of protein transport	GO:0051223	68	0.017
transcription from rna polymerase ii promoter	GO:0006366	252	0.017
response to calcium ion	GO:0051592	59	0.017
regulation of cellular amino acid metabolic process	GO:0006521	2	0.017
carboxylic acid biosynthetic process	GO:0046394	83	0.017
positive regulation of biosynthetic process	GO:0009891	319	0.017
intracellular signal transduction	GO:0035556	314	0.017
blood circulation	GO:0008015	183	0.016
organic acid catabolic process	GO:0016054	49	0.016
quaternary ammonium group transport	GO:0015697	6	0.016
positive regulation of cell projection organization	GO:0031346	111	0.016
positive regulation of response to stimulus	GO:0048584	285	0.016
membrane organization	GO:0061024	94	0.016
regulation of cellular catabolic process	GO:0031329	101	0.016
heterocycle catabolic process	GO:0046700	167	0.016
divalent inorganic cation homeostasis	GO:0072507	165	0.016
transcription dna templated	GO:0006351	377	0.016
response to insulin	GO:0032868	133	0.016
regulation of cellular amine metabolic process	GO:0033238	8	0.016
positive regulation of cell proliferation	GO:0008284	249	0.016
insecticide metabolic process	GO:0017143	4	0.016
indole containing compound metabolic process	GO:0042430	11	0.016
calcitriol biosynthetic process from calciol	GO:0036378	2	0.016
regulation of cellular localization	GO:0060341	263	0.016
immune response	GO:0006955	104	0.016
regulation of ion transmembrane transport	GO:0034765	121	0.015
positive regulation of developmental process	GO:0051094	283	0.015
response to retinoic acid	GO:0032526	63	0.015
regulation of phosphorus metabolic process	GO:0051174	349	0.015
xenobiotic metabolic process	GO:0006805	19	0.015
protein import	GO:0017038	37	0.015
regulation of catalytic activity	GO:0050790	304	0.015
regulation of transcription dna templated	GO:0006355	374	0.015
apoptotic process	GO:0006915	381	0.015
cellular nitrogen compound catabolic process	GO:0044270	163	0.015
small molecule catabolic process	GO:0044282	59	0.015
carbohydrate biosynthetic process	GO:0016051	42	0.015
single organism reproductive process	GO:0044702	297	0.014
alpha amino acid catabolic process	GO:1901606	20	0.014
intracellular protein transport	GO:0006886	79	0.014
male gamete generation	GO:0048232	99	0.014
response to organophosphorus	GO:0046683	102	0.014
multi multicellular organism process	GO:0044706	138	0.014
response to radiation	GO:0009314	137	0.014
cellular response to lipid	GO:0071396	201	0.014
amide transport	GO:0042886	105	0.014
cation homeostasis	GO:0055080	195	0.014
regulation of neurogenesis	GO:0050767	247	0.014
organic acid biosynthetic process	GO:0016053	83	0.014
cellular amino acid biosynthetic process	GO:0008652	32	0.014
response to camp	GO:0051591	91	0.014
liver development	GO:0001889	90	0.014
ribose phosphate biosynthetic process	GO:0046390	87	0.014
negative regulation of natural killer cell mediated cytotoxicity	GO:0045953	4	0.014
immune effector process	GO:0002252	53	0.014
sexual reproduction	GO:0019953	148	0.014
ribose phosphate metabolic process	GO:0019693	235	0.014
response to fungicide	GO:0060992	20	0.014
positive regulation of multicellular organismal process	GO:0051240	387	0.014
positive regulation of molecular function	GO:0044093	230	0.014
rhythmic behavior	GO:0007622	24	0.014
cellular protein localization	GO:0034613	122	0.014
cellular amino acid catabolic process	GO:0009063	21	0.013
nucleotide metabolic process	GO:0009117	279	0.013
visual learning	GO:0008542	8	0.013
negative regulation of cellular biosynthetic process	GO:0031327	161	0.013
monovalent inorganic cation transport	GO:0015672	172	0.013
positive regulation of phosphorus metabolic process	GO:0010562	262	0.013
regulation of signal transduction	GO:0009966	318	0.013
behavior	GO:0007610	205	0.013
vesicle mediated transport	GO:0016192	181	0.013
nucleic acid templated transcription	GO:0097659	379	0.013
response to hydrogen peroxide	GO:0042542	89	0.013
organic hydroxy compound biosynthetic process	GO:1901617	51	0.013
glucose homeostasis	GO:0042593	75	0.013
single organism cellular localization	GO:1902580	102	0.013
monocarboxylic acid metabolic process	GO:0032787	152	0.013
cellular response to glucose stimulus	GO:0071333	65	0.013
ras protein signal transduction	GO:0007265	29	0.013
purine ribonucleotide biosynthetic process	GO:0009152	81	0.013
response to xenobiotic stimulus	GO:0009410	23	0.013
cyclic nucleotide metabolic process	GO:0009187	80	0.013
learning	GO:0007612	33	0.013
positive regulation of cell development	GO:0010720	176	0.013
cellular glucose homeostasis	GO:0001678	66	0.013
negative regulation of signal transduction	GO:0009968	83	0.013
carbohydrate derivative biosynthetic process	GO:1901137	124	0.013
lipid storage	GO:0019915	1	0.013
response to tumor cell	GO:0002347	4	0.012
monoamine transport	GO:0015844	43	0.012
chromosome segregation	GO:0007059	2	0.012
regulation of cellular ketone metabolic process	GO:0010565	27	0.012
amino acid betaine transport	GO:0015838	1	0.012
vitamin a metabolic process	GO:0006776	2	0.012
cellular response to oxidative stress	GO:0034599	76	0.012
cellular response to external stimulus	GO:0071496	118	0.012
acetyl coa metabolic process	GO:0006084	17	0.012
regulation of dendrite development	GO:0050773	59	0.012
single organism intracellular transport	GO:1902582	166	0.012
cellular response to monosaccharide stimulus	GO:0071326	67	0.012
cellular response to inorganic substance	GO:0071241	65	0.012
hepaticobiliary system development	GO:0061008	90	0.012
adult locomotory behavior	GO:0008344	4	0.012
cellular response to xenobiotic stimulus	GO:0071466	19	0.012
cytoplasmic transport	GO:0016482	115	0.012
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.012
positive regulation of nucleotide biosynthetic process	GO:0030810	36	0.012
alcohol biosynthetic process	GO:0046165	38	0.012
regulation of protein localization	GO:0032880	81	0.012
response to amino acid	GO:0043200	75	0.012
metal ion homeostasis	GO:0055065	186	0.012
cellular response to ketone	GO:1901655	51	0.012
neuron death	GO:0070997	127	0.012
establishment of protein localization	GO:0045184	141	0.012
maintenance of location	GO:0051235	17	0.012
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.012
regulation of catabolic process	GO:0009894	113	0.012
response to ketone	GO:1901654	182	0.011
negative regulation of response to external stimulus	GO:0032102	37	0.011
response to electrical stimulus	GO:0051602	56	0.011
cellular carbohydrate metabolic process	GO:0044262	72	0.011
regulation of anion transport	GO:0044070	43	0.011
lipid biosynthetic process	GO:0008610	128	0.011
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
regulation of transmembrane transport	GO:0034762	122	0.011
asymmetric protein localization	GO:0008105	2	0.011
tryptophan catabolic process	GO:0006569	5	0.011
negative regulation of cellular component organization	GO:0051129	83	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.011
response to biotic stimulus	GO:0009607	226	0.011
response to reactive oxygen species	GO:0000302	120	0.011
carnitine transport	GO:0015879	1	0.011
catecholamine transport	GO:0051937	37	0.011
response to oxygen levels	GO:0070482	265	0.011
programmed cell death	GO:0012501	392	0.011
insulin secretion	GO:0030073	69	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.011
thioester metabolic process	GO:0035383	28	0.011
cellular cation homeostasis	GO:0030003	180	0.011
establishment of synaptic vesicle localization	GO:0097480	23	0.011
estrogen metabolic process	GO:0008210	11	0.011
cytoplasmic sequestering of protein	GO:0051220	3	0.011
negative regulation of biosynthetic process	GO:0009890	168	0.011
axis specification	GO:0009798	4	0.011
regulation of blood circulation	GO:1903522	110	0.011
organelle localization	GO:0051640	55	0.010
meiotic cell cycle process	GO:1903046	3	0.010
negative regulation of response to stimulus	GO:0048585	155	0.010
nuclear import	GO:0051170	35	0.010
inorganic cation transmembrane transport	GO:0098662	202	0.010
cellular response to carbohydrate stimulus	GO:0071322	72	0.010
response to hypoxia	GO:0001666	231	0.010
response to external biotic stimulus	GO:0043207	221	0.010
positive regulation of cyclase activity	GO:0031281	15	0.010
cellular response to growth factor stimulus	GO:0071363	162	0.010
spermatogenesis	GO:0007283	99	0.010
protein tetramerization	GO:0051262	38	0.010
tissue development	GO:0009888	252	0.010
peptide transport	GO:0015833	97	0.010
regulation of response to wounding	GO:1903034	69	0.010
response to molecule of bacterial origin	GO:0002237	194	0.010
regulation of cyclic nucleotide metabolic process	GO:0030799	51	0.010
positive regulation of cell differentiation	GO:0045597	217	0.010
response to epidermal growth factor	GO:0070849	18	0.010
purine containing compound biosynthetic process	GO:0072522	85	0.010
embryonic pattern specification	GO:0009880	1	0.010
sex differentiation	GO:0007548	113	0.010
hepatocyte proliferation	GO:0072574	3	0.010
regulation of notch signaling pathway	GO:0008593	3	0.010

Pdzk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of metabolism	DOID:0014667	0	0.025
	inherited metabolic disorder	DOID:655	0	0.014

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